Thomas Nickel

Summary

Country: Germany

Publications

  1. doi request reprint oxLDL uptake by dendritic cells induces upregulation of scavenger-receptors, maturation and differentiation
    Thomas Nickel
    Medizinische Klinik und Poliklinik I, University Hospital Munich Grosshadern, Ludwig Maximilians University, Munich, Germany
    Atherosclerosis 205:442-50. 2009
  2. pmc oxLDL downregulates the dendritic cell homing factors CCR7 and CCL21
    Thomas Nickel
    Medizinische Klinik und Poliklinik I, Campus Grosshadern, Ludwig Maximilians University, 81377 Munich, Germany
    Mediators Inflamm 2012:320953. 2012
  3. doi request reprint Modulation of dendritic cells and toll-like receptors by marathon running
    Thomas Nickel
    Medizinische Klinik und Poliklinik 1, Campus Grosshadern, Ludwig Maximilians Universitat Munchen, Marchioninistr 15, 81377 Munich, Germany
    Eur J Appl Physiol 112:1699-708. 2012
  4. doi request reprint Extreme exercise enhances chromogranin A levels correlating with stress levels but not with cardiac burden
    T Nickel
    Medizinische Klinik und Poliklinik 1, Campus Grosshadern, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Atherosclerosis 220:219-22. 2012
  5. doi request reprint Coronary dilatation after heart transplantation
    Thomas Nickel
    Medizinische Klinik und Poliklinik 1, Campus Großhadern, Ludwig Maximilians Universitat, Munich, Germany
    Transplantation 92:697-702. 2011
  6. doi request reprint Immunoregulatory effects of the flavonol quercetin in vitro and in vivo
    Thomas Nickel
    Medizinische Klinik und Poliklinik I, Campus Grosshadern, Ludwig Maximilians and University of Munich, 81377, Munich, Germany
    Eur J Nutr 50:163-72. 2011
  7. pmc Immunomodulatory effects of aerobic training in obesity
    Thomas Nickel
    Medizinische Klinik und Poliklinik I, Campus Grosshadern, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Mediators Inflamm 2011:308965. 2011
  8. doi request reprint Modification of endothelial biology by acute and chronic stress hormones
    T Nickel
    Medizinische Klinik und Poliklinik I, Campus Grosshadern, Ludwig Maximilians Universitat, Munchen, Germany
    Microvasc Res 78:364-9. 2009
  9. doi request reprint Impact of coronary endothelial dysfunction on adverse long-term outcome after heart transplantation
    Marion Kübrich
    Divisions of Cardiology and Cardiovascular Surgery, University Hospital Grosshadern, Ludwig Maximilians University of Munich, Munich, Germany
    Transplantation 85:1580-7. 2008
  10. ncbi request reprint Dual mode of HMG-CoA reductase inhibition on dendritic cell invasion
    Sieglinde Kofler
    Medizinische Klinik und Poliklinik I, University Medical Center Munich Grosshadern, Ludwig Maximilians University of Munich, Munich, Germany
    Atherosclerosis 197:105-10. 2008

Collaborators

Detail Information

Publications19

  1. doi request reprint oxLDL uptake by dendritic cells induces upregulation of scavenger-receptors, maturation and differentiation
    Thomas Nickel
    Medizinische Klinik und Poliklinik I, University Hospital Munich Grosshadern, Ludwig Maximilians University, Munich, Germany
    Atherosclerosis 205:442-50. 2009
    ..In addition, we analyzed the impact of oxLDL on the nuclear transcription factor-kappa B (NF-kappaB)-pathway...
  2. pmc oxLDL downregulates the dendritic cell homing factors CCR7 and CCL21
    Thomas Nickel
    Medizinische Klinik und Poliklinik I, Campus Grosshadern, Ludwig Maximilians University, 81377 Munich, Germany
    Mediators Inflamm 2012:320953. 2012
    ..Our aim was to investigate the role of oxLDL in the modulation of the DC homing-receptor CCR7 and endothelial-ligand CCL21...
  3. doi request reprint Modulation of dendritic cells and toll-like receptors by marathon running
    Thomas Nickel
    Medizinische Klinik und Poliklinik 1, Campus Grosshadern, Ludwig Maximilians Universitat Munchen, Marchioninistr 15, 81377 Munich, Germany
    Eur J Appl Physiol 112:1699-708. 2012
    ..Myeloid and plasmacytoid DCs are differently affected by the excessive physical stress. Immunomodulatory mechanisms seem to play a key role in the response and adaptation to acute excessive exercise...
  4. doi request reprint Extreme exercise enhances chromogranin A levels correlating with stress levels but not with cardiac burden
    T Nickel
    Medizinische Klinik und Poliklinik 1, Campus Grosshadern, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Atherosclerosis 220:219-22. 2012
    ..Stress and heart failure are associated with increased systemic levels of chromogranin A (CGA). Here we analyzed the effects of marathon running on systemic CGA levels and the association with cardiac burden and stress...
  5. doi request reprint Coronary dilatation after heart transplantation
    Thomas Nickel
    Medizinische Klinik und Poliklinik 1, Campus Großhadern, Ludwig Maximilians Universitat, Munich, Germany
    Transplantation 92:697-702. 2011
    ..2% to 5%. The endothelial-dependent and -independent causes for CD are postulated. So far, the incidence and prognosis of CD after heart transplantation is unknown...
  6. doi request reprint Immunoregulatory effects of the flavonol quercetin in vitro and in vivo
    Thomas Nickel
    Medizinische Klinik und Poliklinik I, Campus Grosshadern, Ludwig Maximilians and University of Munich, 81377, Munich, Germany
    Eur J Nutr 50:163-72. 2011
    ..We aimed to characterize the impact of the flavonol quercetin on DC activity and differentiation in vitro and in vivo...
  7. pmc Immunomodulatory effects of aerobic training in obesity
    Thomas Nickel
    Medizinische Klinik und Poliklinik I, Campus Grosshadern, Ludwig Maximilians Universitat Munchen, Munich, Germany
    Mediators Inflamm 2011:308965. 2011
    ..Markers of the innate immune response were investigated in obese (ONE: ET≤40 km/week) and lean athletes (LNE: ET≤40 km/week and LE: ET≥55 km/week)...
  8. doi request reprint Modification of endothelial biology by acute and chronic stress hormones
    T Nickel
    Medizinische Klinik und Poliklinik I, Campus Grosshadern, Ludwig Maximilians Universitat, Munchen, Germany
    Microvasc Res 78:364-9. 2009
    ..The present study was designed to evaluate the relationship between acute (epi- and norepinephrine) and chronic stress hormones (dexamethasone, beta-endorphin, corticotropin releasing hormone) and endothelial dysfunction...
  9. doi request reprint Impact of coronary endothelial dysfunction on adverse long-term outcome after heart transplantation
    Marion Kübrich
    Divisions of Cardiology and Cardiovascular Surgery, University Hospital Grosshadern, Ludwig Maximilians University of Munich, Munich, Germany
    Transplantation 85:1580-7. 2008
    ..The present prospective study tested whether endothelial dysfunction independently predicts cardiovascular-related events and death after heart transplantation (HTx)...
  10. ncbi request reprint Dual mode of HMG-CoA reductase inhibition on dendritic cell invasion
    Sieglinde Kofler
    Medizinische Klinik und Poliklinik I, University Medical Center Munich Grosshadern, Ludwig Maximilians University of Munich, Munich, Germany
    Atherosclerosis 197:105-10. 2008
    ..As DCs control immunity, regulating DC/endothelial cell interaction by statins may have relevance to inflammation and atherogenesis...
  11. doi request reprint Magnetic resonance imaging of myocardial injury and ventricular torsion after marathon running
    Henner Hanssen
    Department of Prevention and Sports Medicine, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Clin Sci (Lond) 120:143-52. 2011
    ..The stress of marathon running seems to be better described as a burden of myocardial overstimulation rather than cardiac injury...
  12. ncbi request reprint Gender-based analysis of outcome after heart transplantation
    Sandra Eifert
    Department for Cardiac Surgery, Ludwig Maximilians University, Munich, Germany
    Exp Clin Transplant 10:368-74. 2012
    ..Literature and registries reveal controversial results. We reviewed 1000 heart transplantations at our center focusing on the influence of gender differences on short- and long-term outcome after heart transplantation...
  13. doi request reprint Tacrolimus with mycophenolate mofetil or sirolimus compared with calcineurin inhibitor-free immunosuppression (sirolimus/mycophenolate mofetil) after heart transplantation: 5-year results
    Ingo Kaczmarek
    Transplantation Center Munich, Ludwig Maximilians University, Munich, Germany
    J Heart Lung Transplant 32:277-84. 2013
    ..This randomized controlled trial was performed to evaluate the efficacy and safety of 3 immunosuppressive protocols...
  14. doi request reprint Cell matrix contact modifies endothelial major histocompatibility complex class II expression in high-glucose environment
    Markus Nickmann
    Department of Internal Medicine Cardiology, University Hospital Grosshadern, Ludwig Maximilians University, Munich, Germany
    Am J Physiol Heart Circ Physiol 305:H1592-9. 2013
    ..Increased SOCS expression raises the threshold for IFN-γ to induce HLA-DR expression in a 3-D environment. This immunoprotective effect is maintained even in states of experimental hyperglycemia...
  15. ncbi request reprint Combination antifungal therapy for invasive pulmonary aspergillosis in a heart transplant recipient
    Andres Beiras-Fernandez
    Department of Cardiac Surgery, Klinikum Grosshadern, Ludwig Maximilians University, D 81377 Munich, Germany
    Exp Clin Transplant 9:279-83. 2011
    ..This case report highlights the importance of a high degree of clinical suspicion to allow curative treatment of invasive aspergillosis and the efficiency of new antifungal drugs...
  16. ncbi request reprint Role of cytokines in cardiovascular diseases: a focus on endothelial responses to inflammation
    Sieglinde Kofler
    Department of Cardiology, University Hospital Munich Grosshadern, Ludwig Maximilians University of Munich, 81377 Munich, Germany
    Clin Sci (Lond) 108:205-13. 2005
    ..This review will focus on the vascular mechanisms orchestrated by cytokines and summarizes the current knowledge concerning the contribution of cytokines to cardiovascular diseases...
  17. ncbi request reprint Drugs modulating endothelial function after transplantation
    Thomas Nickel
    Medizinische Klinik und Poliklinik I, University Hospital Munich Grosshadern, Ludwig Maximilians University of Munich, Germany
    Transplantation 82:S41-6. 2006
    ..We briefly review the evidence supporting their use as protection for endothelial cells in transplant recipients...
  18. doi request reprint Modified serum profiles of inflammatory and vasoconstrictive factors in patients with emotional stress-induced acute coronary syndrome during World Cup Soccer 2006
    Ute Wilbert-Lampen
    Medizinische Klinik und Poliklinik I, Ludwig Maximilians Universitat Munchen, Munich, Germany
    J Am Coll Cardiol 55:637-42. 2010
    ..We sought to assess whether emotional stress-induced acute coronary syndrome (ACS) is mediated by increased inflammatory and vasoconstrictive mediators...
  19. pmc Cardiac Output Measurements in Septic Patients: Comparing the Accuracy of USCOM to PiCCO
    Sophia Horster
    Medical Department II, Ludwig Maximilian University of Munich, Campus Großhadern, Marchioninistrase 15, 81377 Munich, Germany
    Crit Care Res Pract 2012:270631. 2012
    ..USCOM does reliably represent CO values as compared to the reference technique based on thermodilution (PiCCO). It seems to be appropriate in situations where CO measurements are most pertinent to patient management...