Horst Neubauer

Summary

Country: Germany

Publications

  1. ncbi Influence of glycaemic control on platelet bound CD40-CD40L system, P-selectin and soluble CD40 ligand in Type 2 diabetes
    H Neubauer
    Medical Clinic II, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    Diabet Med 27:384-90. 2010
  2. ncbi How to optimise clopidogrel therapy? Reducing the low-response incidence by aggregometry-guided therapy modification
    Horst Neubauer
    Clinic of Cardiology and Angiology, St Josef Hospital BG Kliniken Bergmannsheil, University Hospitals, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
    Thromb Haemost 99:357-62. 2008
  3. ncbi Comparing the antiplatelet effect of clopidogrel hydrogensulfate and clopidogrel besylate: a crossover study
    Horst Neubauer
    Cardiovascular Center, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791, Bochum, Germany
    Clin Res Cardiol 98:533-40. 2009
  4. ncbi Upregulation of platelet CD40, CD40 ligand (CD40L) and P-Selectin expression in cigarette smokers: a flow cytometry study
    Horst Neubauer
    Cardiovascular Center, Ruhr University Bochum, Germany
    Blood Coagul Fibrinolysis 20:694-8. 2009
  5. ncbi Pantoprazole does not influence the antiplatelet effect of clopidogrel-a whole blood aggregometry study after coronary stenting
    Horst Neubauer
    Ruhr University Bochum, Cardiovascular Center, St Josef Hospital, Bochum, Germany
    J Cardiovasc Pharmacol 56:91-7. 2010
  6. ncbi Tailored antiplatelet therapy can overcome clopidogrel and aspirin resistance--the BOchum CLopidogrel and Aspirin Plan (BOCLA-Plan) to improve antiplatelet therapy
    Horst Neubauer
    Cardiovascular Center, Ruhr University Bochum, St, Josef Hospital, Gudrunstr, 56, D 44791 Bochum, Germany
    BMC Med 9:3. 2011
  7. ncbi Which is the best anticoagulant for whole blood aggregometry platelet function testing? Comparison of six anticoagulants and diverse storage conditions
    Andreas Friedrich Christoph Kaiser
    Cardiovascular Center, Ruhr University Bochum, St Josef Hospital, Gudrunstraße 56, Bochum, Germany
    Platelets 23:359-67. 2012
  8. ncbi Dose-dependent effect of early antiplatelet therapy in acute ischaemic stroke
    Saskia H Meves
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, D 44791 Bochum, Germany
    Thromb Haemost 107:69-79. 2012
  9. ncbi The CYP2J2 G-50T polymorphism and myocardial infarction in patients with cardiovascular risk profile
    Jan Borgel
    Department of Cardiology, St, Josef Hospital Bergmannsheil, Ruhr University, Bochum, Germany
    BMC Cardiovasc Disord 8:41. 2008
  10. ncbi Lipophilic statins interfere with the inhibitory effects of clopidogrel on platelet function--a flow cytometry study
    Horst Neubauer
    Clinic of Cardiology and Angiology, Ruhr-University, Bochum, Germany
    Eur Heart J 24:1744-9. 2003

Collaborators

Detail Information

Publications14

  1. ncbi Influence of glycaemic control on platelet bound CD40-CD40L system, P-selectin and soluble CD40 ligand in Type 2 diabetes
    H Neubauer
    Medical Clinic II, St Josef Hospital, Ruhr University Bochum, Bochum, Germany
    Diabet Med 27:384-90. 2010
    ..The purpose of this study was to investigate whether platelet-bound CD40-CD40L signalling, P-selectin expression and soluble CD40L were increased in patients with diabetes mellitus and can be normalized by improving glycaemic control...
  2. ncbi How to optimise clopidogrel therapy? Reducing the low-response incidence by aggregometry-guided therapy modification
    Horst Neubauer
    Clinic of Cardiology and Angiology, St Josef Hospital BG Kliniken Bergmannsheil, University Hospitals, Ruhr University Bochum, Gudrunstrasse 56, 44791 Bochum, Germany
    Thromb Haemost 99:357-62. 2008
    ..6% to 5.0%. Our aggregometer-guided therapeutic algorithm reduced the relative percentage of clopidogrel LR by 78.9%. This approach could prove to be helpful in achieving a further decrease in the incidence of clopidogrel resistance...
  3. ncbi Comparing the antiplatelet effect of clopidogrel hydrogensulfate and clopidogrel besylate: a crossover study
    Horst Neubauer
    Cardiovascular Center, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, 44791, Bochum, Germany
    Clin Res Cardiol 98:533-40. 2009
    ....
  4. ncbi Upregulation of platelet CD40, CD40 ligand (CD40L) and P-Selectin expression in cigarette smokers: a flow cytometry study
    Horst Neubauer
    Cardiovascular Center, Ruhr University Bochum, Germany
    Blood Coagul Fibrinolysis 20:694-8. 2009
    ..These findings emphasize that cigarette smoking leads to a proinflammatory and prothrombotic state thus contributing to accelerated atherosclerosis...
  5. ncbi Pantoprazole does not influence the antiplatelet effect of clopidogrel-a whole blood aggregometry study after coronary stenting
    Horst Neubauer
    Ruhr University Bochum, Cardiovascular Center, St Josef Hospital, Bochum, Germany
    J Cardiovasc Pharmacol 56:91-7. 2010
    ..Therefore, the use of pantoprazole seems preferable in patients treated with clopidogrel when a concomitant medication with a PPI is indicated...
  6. ncbi Tailored antiplatelet therapy can overcome clopidogrel and aspirin resistance--the BOchum CLopidogrel and Aspirin Plan (BOCLA-Plan) to improve antiplatelet therapy
    Horst Neubauer
    Cardiovascular Center, Ruhr University Bochum, St, Josef Hospital, Gudrunstr, 56, D 44791 Bochum, Germany
    BMC Med 9:3. 2011
    ..The aim of this single-center prospective study was to reduce the low response incidence of dual antiplatelet therapy with ASA and clopidogrel according to a prespecified therapy algorithm...
  7. ncbi Which is the best anticoagulant for whole blood aggregometry platelet function testing? Comparison of six anticoagulants and diverse storage conditions
    Andreas Friedrich Christoph Kaiser
    Cardiovascular Center, Ruhr University Bochum, St Josef Hospital, Gudrunstraße 56, Bochum, Germany
    Platelets 23:359-67. 2012
    ..In conclusion, sodium heparin and 45 µg/mL r-hirudin as anticoagulants guarantee the longest storage time for impedance aggregometry...
  8. ncbi Dose-dependent effect of early antiplatelet therapy in acute ischaemic stroke
    Saskia H Meves
    Department of Neurology, St Josef Hospital, Ruhr University Bochum, Gudrunstrasse 56, D 44791 Bochum, Germany
    Thromb Haemost 107:69-79. 2012
    ..Our findings suggest using a loading dose of 500 mg ASA intravenously as this seems to be favourable when a sufficient early platelet inhibitory effect is wanted...
  9. ncbi The CYP2J2 G-50T polymorphism and myocardial infarction in patients with cardiovascular risk profile
    Jan Borgel
    Department of Cardiology, St, Josef Hospital Bergmannsheil, Ruhr University, Bochum, Germany
    BMC Cardiovasc Disord 8:41. 2008
    ..In the present study, we investigated the influence of this polymorphism on survived myocardial infarction in two study groups of patients with on average high cardiovascular risk profile...
  10. ncbi Lipophilic statins interfere with the inhibitory effects of clopidogrel on platelet function--a flow cytometry study
    Horst Neubauer
    Clinic of Cardiology and Angiology, Ruhr-University, Bochum, Germany
    Eur Heart J 24:1744-9. 2003
    ..It may be reasonable to test the therapeutic efficacy of clopidogrel in those patients who require long-term treatment...
  11. ncbi BAPA, a synthetic dual inhibitor of Factor Xa and Thrombin, extends the storage-time to a maximum of 12 hours in ADP- and 24 hours in arachidonic acid-induced impedance aggregometry
    Andreas F C Kaiser
    Cardiovascular Center, St Josef Hospital, Ruhr University, Bochum, Germany
    Scand J Clin Lab Invest 71:253-6. 2011
    ..Further studies including blood samples of patients and the comparison of BAPA to other anticoagulants are necessary to define the potential role of BAPA anticoagulated samples...
  12. ncbi Unrecognized secondary causes of hypertension in patients with hypertensive urgency/emergency: prevalence and co-prevalence
    Jan Borgel
    Department of Cardiology and Angiology, University Clinic St Josef Hospital, Heart Center, University of Bochum, Germany
    Clin Res Cardiol 99:499-506. 2010
    ..Hypertensive urgency/emergency occurs frequently, yet no prospective data on common secondary causes, including sleep apnea (SA), renal artery stenosis (RAS), and hyperaldosteronism, are available...
  13. ncbi Ventricular tachycardia during basilar-type migraine attack
    Kalliopi Pitarokoili
    Department of Neurology, Ruhr University, St Josef Hospital, Bochum, Germany
    Ther Adv Neurol Disord 6:35-40. 2013
    ..The therapeutic implications of such a co-occurrence as well as a possible relationship between ventricular tachycardia and the underlying biology of basilar-type migraine are discussed...
  14. ncbi Is there an ideal way to initiate antiplatelet therapy with aspirin? A crossover study on healthy volunteers evaluating different dosing schemes with whole blood aggregometry
    Saskia H Meves
    Ruhr University Bochum, Department of Neurology, St, Josef Hospital, Gudrunstrasse 56, D 44791 Bochum, Germany
    BMC Res Notes 4:106. 2011
    ..This study evaluated the platelet inhibitory effect in healthy volunteers by using three different aspirin loading doses to gain a model for initiating antiplatelet treatment in acute strokes patients...