- Ten years of gene targeting: targeted mouse mutants, from vector design to phenotype analysisU Muller
Max Planck Institute for Brain Research, Deutschordenstr 46, D 60528, Frankfurt, Germany
Mech Dev 82:3-21. 1999..Many examples from different areas of biomedical research are given to illustrate the purpose and limitations of the employed experimental approaches...
- Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family membersS Heber
Department of Neurochemistry, Max Planck Institute for Brain Research, D 60528 Frankfurt, Germany
J Neurosci 20:7951-63. 2000..Moreover, cortical neurons from single or combined mutant mice showed unaltered survival rates under basal culture conditions and unaltered susceptibility to glutamate excitotoxicity in vitro...