Armen Y Mulkidjanian

Summary

Country: Germany

Publications

  1. pmc Survival of the fittest before the beginning of life: selection of the first oligonucleotide-like polymers by UV light
    Armen Y Mulkidjanian
    Division of Biophysics, Department of Biology and Chemistry, Universitat Osnabruck, D 49069 Osnabruck, Germany
    BMC Evol Biol 3:12. 2003
  2. ncbi request reprint Proton translocation by the cytochrome bc1 complexes of phototrophic bacteria: introducing the activated Q-cycle
    Armen Y Mulkidjanian
    A N Belozersky Institute of Physico Chemical Biology, Moscow State University, 119899, Moscow, Russia
    Photochem Photobiol Sci 6:19-34. 2007
  3. ncbi request reprint Inventing the dynamo machine: the evolution of the F-type and V-type ATPases
    Armen Y Mulkidjanian
    School of Physics, University of Osnabruck, Osnabrück D 49069, Germany
    Nat Rev Microbiol 5:892-9. 2007
  4. pmc Evolutionary primacy of sodium bioenergetics
    Armen Y Mulkidjanian
    School of Physics, University of Osnabruck, D 49069 Osnabruck, Germany
    Biol Direct 3:13. 2008
  5. doi request reprint Open questions on the origin of life at anoxic geothermal fields
    Armen Y Mulkidjanian
    School of Physics, University of Osnabrueck, Barbarastrasse 7, 49076 Osnabrueck, Germany
    Orig Life Evol Biosph 42:507-16. 2012
  6. pmc Origin of first cells at terrestrial, anoxic geothermal fields
    Armen Y Mulkidjanian
    School of Physics, University of Osnabruck, D 49069 Osnabruck, Germany
    Proc Natl Acad Sci U S A 109:E821-30. 2012
  7. ncbi request reprint Physico-chemical and evolutionary constraints for the formation and selection of first biopolymers: towards the consensus paradigm of the abiogenic origin of life
    Armen Y Mulkidjanian
    School of Physics, Universitat Osnabruck, D 49069 Osnabruck
    Chem Biodivers 4:2003-15. 2007
  8. pmc The past and present of sodium energetics: may the sodium-motive force be with you
    Armen Y Mulkidjanian
    School of Physics, University of Osnabruck, D 49069 Osnabruck, Germany
    Biochim Biophys Acta 1777:985-92. 2008
  9. pmc Co-evolution of primordial membranes and membrane proteins
    Armen Y Mulkidjanian
    School of Physics, University of Osnabruck, D 49069 Osnabruck, Germany
    Trends Biochem Sci 34:206-15. 2009
  10. pmc On the origin of life in the zinc world: 1. Photosynthesizing, porous edifices built of hydrothermally precipitated zinc sulfide as cradles of life on Earth
    Armen Y Mulkidjanian
    School of Physics, Universitat Osnabruck, D 49069 Osnabruck, Germany
    Biol Direct 4:26. 2009

Detail Information

Publications27

  1. pmc Survival of the fittest before the beginning of life: selection of the first oligonucleotide-like polymers by UV light
    Armen Y Mulkidjanian
    Division of Biophysics, Department of Biology and Chemistry, Universitat Osnabruck, D 49069 Osnabruck, Germany
    BMC Evol Biol 3:12. 2003
    ..However, so far there has been no explanation of how the first RNA-like biopolymers could originate and survive on the primordial Earth...
  2. ncbi request reprint Proton translocation by the cytochrome bc1 complexes of phototrophic bacteria: introducing the activated Q-cycle
    Armen Y Mulkidjanian
    A N Belozersky Institute of Physico Chemical Biology, Moscow State University, 119899, Moscow, Russia
    Photochem Photobiol Sci 6:19-34. 2007
    ..Then the oxidation of each ubiquinol molecule in center P is followed by ubiquinol formation in center N, proton translocation and generation of membrane voltage...
  3. ncbi request reprint Inventing the dynamo machine: the evolution of the F-type and V-type ATPases
    Armen Y Mulkidjanian
    School of Physics, University of Osnabruck, Osnabrück D 49069, Germany
    Nat Rev Microbiol 5:892-9. 2007
    ..We suggest that in these ancestral translocases, the position of the central stalk was occupied by the translocated polymer...
  4. pmc Evolutionary primacy of sodium bioenergetics
    Armen Y Mulkidjanian
    School of Physics, University of Osnabruck, D 49069 Osnabruck, Germany
    Biol Direct 3:13. 2008
    ..The prevalent proton-dependent ATPases are generally viewed as the primary form of the enzyme whereas the sodium-translocating ATPases of some prokaryotes are usually construed as an exotic adaptation to survival in extreme environments...
  5. doi request reprint Open questions on the origin of life at anoxic geothermal fields
    Armen Y Mulkidjanian
    School of Physics, University of Osnabrueck, Barbarastrasse 7, 49076 Osnabrueck, Germany
    Orig Life Evol Biosph 42:507-16. 2012
    ....
  6. pmc Origin of first cells at terrestrial, anoxic geothermal fields
    Armen Y Mulkidjanian
    School of Physics, University of Osnabruck, D 49069 Osnabruck, Germany
    Proc Natl Acad Sci U S A 109:E821-30. 2012
    ....
  7. ncbi request reprint Physico-chemical and evolutionary constraints for the formation and selection of first biopolymers: towards the consensus paradigm of the abiogenic origin of life
    Armen Y Mulkidjanian
    School of Physics, Universitat Osnabruck, D 49069 Osnabruck
    Chem Biodivers 4:2003-15. 2007
    ..The key feature of the scenario is the participation of the UV irradiation both as driving and selecting forces during the earlier stages of evolution...
  8. pmc The past and present of sodium energetics: may the sodium-motive force be with you
    Armen Y Mulkidjanian
    School of Physics, University of Osnabruck, D 49069 Osnabruck, Germany
    Biochim Biophys Acta 1777:985-92. 2008
    ....
  9. pmc Co-evolution of primordial membranes and membrane proteins
    Armen Y Mulkidjanian
    School of Physics, University of Osnabruck, D 49069 Osnabruck, Germany
    Trends Biochem Sci 34:206-15. 2009
    ..We argue that evolution of biological membranes occurred as a process of co-evolution of lipid bilayers, membrane proteins and membrane bioenergetics...
  10. pmc On the origin of life in the zinc world: 1. Photosynthesizing, porous edifices built of hydrothermally precipitated zinc sulfide as cradles of life on Earth
    Armen Y Mulkidjanian
    School of Physics, Universitat Osnabruck, D 49069 Osnabruck, Germany
    Biol Direct 4:26. 2009
    ..Their number, however, can be dramatically reduced by the simultaneous consideration of various bioenergetic, physical, and geological constraints...
  11. pmc On the origin of life in the zinc world. 2. Validation of the hypothesis on the photosynthesizing zinc sulfide edifices as cradles of life on Earth
    Armen Y Mulkidjanian
    School of Physics, Universitat Osnabruck, D 49069 Osnabruck, Germany
    Biol Direct 4:27. 2009
    ..The hypothesis suggests that life emerged within compartmentalized, photosynthesizing ZnS formations of hydrothermal origin (the Zn world), assembled in sub-aerial settings on the surface of the primeval Earth...
  12. doi request reprint Activated Q-cycle as a common mechanism for cytochrome bc1 and cytochrome b6f complexes
    Armen Y Mulkidjanian
    School of Physics, University of Osnabruck, D 49069 Osnabruck, Germany
    Biochim Biophys Acta 1797:1858-68. 2010
    ..Here it is argued that a similar pre-loading by two electrons can explain the available data on flash-induced reactions in cytochrome b(6)f-complexes of green plants and cyanobacteria...
  13. pmc The cyanobacterial genome core and the origin of photosynthesis
    Armen Y Mulkidjanian
    School of Physics, University of Osnabruck, D 49069 Osnabruck, Germany
    Proc Natl Acad Sci U S A 103:13126-31. 2006
    ..From procyanobacteria, photosynthesis spread to other phyla by way of lateral gene transfer...
  14. ncbi request reprint Proton in the well and through the desolvation barrier
    Armen Y Mulkidjanian
    A N Belozersky Institute of Physico Chemical Biology, Moscow State University, 119899, Moscow, Russia
    Biochim Biophys Acta 1757:415-27. 2006
    ..g., release of another proton from the membrane into the aqueous phase. It is argued that the proton transfer in the ATP synthase and the cytochrome bc complex could proceed in this way...
  15. ncbi request reprint Probing biological interfaces by tracing proton passage across them
    Armen Y Mulkidjanian
    A N Belozersky Institute of Physico Chemical Biology, Moscow State University, Moscow 119899, Russia
    Photochem Photobiol Sci 5:577-87. 2006
    ..It is discussed how the interfacial potential barrier can affect the reactions at interface, especially those coupled with biological energy conversion and membrane transport...
  16. ncbi request reprint Protons @ interfaces: implications for biological energy conversion
    Armen Y Mulkidjanian
    AN Belozersky Institute of Physico Chemical Biology, Moscow State University, Moscow, Russia
    Biochim Biophys Acta 1757:913-30. 2006
    ..This trait should increase the driving force for ATP synthesis, especially in the case of alkaliphilic bacteria...
  17. ncbi request reprint Met23Lys mutation in subunit gamma of F(O)F(1)-ATP synthase from Rhodobacter capsulatus impairs the activation of ATP hydrolysis by protonmotive force
    Boris A Feniouk
    Division of Biophysics, School of Biology Chemistry, University of Osnabruck, D 49069, Osnabruck, Germany
    Biochim Biophys Acta 1767:1319-30. 2007
    ....
  18. ncbi request reprint Proton slip in the ATP synthase of Rhodobacter capsulatus: induction, proton conduction, and nucleotide dependence
    Boris A Feniouk
    Division of Biophysics, Faculty of Biology Chemistry, University of Osnabruck, D 49069 Osnabruck, Germany
    Biochim Biophys Acta 1706:184-94. 2005
    ..Proton slip probably presents the free-wheeling of the central rotary shaft, subunit gamma, in an open structure of the (alphabeta)3 hexagon with no nucleotides in the catalytic sites...
  19. pmc Proton transfer dynamics at the membrane/water interface: dependence on the fixed and mobile pH buffers, on the size and form of membrane particles, and on the interfacial potential barrier
    Dmitry A Cherepanov
    Division of Biophysics, Faculty of Biology Chemistry, University of Osnabruck, D 49069 Osnabruck, Germany
    Biophys J 86:665-80. 2004
    ....
  20. doi request reprint The role of energy in the emergence of biology from chemistry
    Daria V Dibrova
    School of Physics, University of Osnabruck, 49069 Osnabruck, Germany
    Orig Life Evol Biosph 42:459-68. 2012
    ..We argue that, in the course of evolution, sodium-dependent membrane energetics preceded the proton-based energetics which evolved independently in bacteria and archaea...
  21. pmc Characterization of the N-ATPase, a distinct, laterally transferred Na+-translocating form of the bacterial F-type membrane ATPase
    Daria V Dibrova
    School of Physics, University of Osnabruck, D 49069 Osnabruck, Germany
    Bioinformatics 26:1473-6. 2010
    ..We argue that N-ATPases are an early-diverging branch of membrane ATPases that, similarly to the eukaryotic V-type ATPases, do not synthesize ATP. Supplementary information: Supplementary data are available at Bioinformatics online...
  22. ncbi request reprint Flash-induced turnover of the cytochrome bc1 complex in chromatophores of Rhodobacter capsulatus: binding of Zn2+ decelerates likewise the oxidation of cytochrome b, the reduction of cytochrome c1 and the voltage generation
    Sergey S Klishin
    Division of Biophysics, Department of Biology and Chemistry, University of Osnabruck, D 49069, Osnabruck, Germany
    Biochim Biophys Acta 1553:177-82. 2002
    ....
  23. pmc Chromatophore vesicles of Rhodobacter capsulatus contain on average one F(O)F(1)-ATP synthase each
    Boris A Feniouk
    Division of Biophysics, Faculty of Biology Chemistry, University of Osnabruck, D 49069 Osnabruck, Germany
    Biophys J 82:1115-22. 2002
    ..Thereby chromatophores of Rhodobacter capsulatus provide a system where the coupling of proton transfer to ATP synthesis can be studied in a single enzyme/single vesicle mode...
  24. ncbi request reprint Proton transfer in the photosynthetic reaction center of Blastochloris viridis
    Maria A Kozlova
    A N Belozersky Institute of Physico Chemical Biology, Moscow State University, Moscow, Russia
    FEBS Lett 582:238-42. 2008
    ..The kinetics after the second flash featured temperature-independent components of 5 micros and 200 micros followed by a component of 600 micros with E(a) approximately 60 kJ/mol...
  25. pmc The proton-driven rotor of ATP synthase: ohmic conductance (10 fS), and absence of voltage gating
    Boris A Feniouk
    Division of Biophysics, Faculty of Biology Chemistry, University of Osnabruck, Osnabruck, Germany
    Biophys J 86:4094-109. 2004
    ..The data fit attributed pK values of approximately 6 and approximately 10 to these relays, and placed them close to the membrane/electrolyte interface...
  26. pmc Low dielectric permittivity of water at the membrane interface: effect on the energy coupling mechanism in biological membranes
    Dmitry A Cherepanov
    Division of Biophysics, Faculty of Biology Chemistry, University of Osnabruck, Osnabruck, Germany
    Biophys J 85:1307-16. 2003
    ..These results provide a rationale to solve the long-lasting problem of the seemingly insufficient protonmotive force in mesophilic and alkaliphilic bacteria...
  27. ncbi request reprint Ubiquinol oxidation in the cytochrome bc1 complex: reaction mechanism and prevention of short-circuiting
    Armen Y Mulkidjanian
    Max Planck Institute of Biophysics, Department of Biophysical Chemistry, Max von Laue Str 3, D 60438 Frankfurt am Main, Germany
    Biochim Biophys Acta 1709:5-34. 2005
    ....