Ralph Mosges

Summary

Country: Germany

Publications

  1. pmc Treatment of acute otitis externa with ciprofloxacin otic 0.2% antibiotic ear solution
    R Mosges
    Institute of Medical Statistics, Informatics and Epidemiology, Faculty of Medicine, University of Cologne, Germany
    Ther Clin Risk Manag 7:325-36. 2011
  2. pmc Tolerability and effects on quality of life of liposomal nasal spray treatment compared to nasal ointment containing dexpanthenol or isotonic NaCl spray in patients with rhinitis sicca
    C Hahn
    Institute of Medical Statistics, Informatics and Epidemiology IMSIE, University of Cologne, 50924 Cologne, Germany
    Eur Arch Otorhinolaryngol 270:2465-72. 2013
  3. pmc EAACI: A European Declaration on Immunotherapy. Designing the future of allergen specific immunotherapy
    Moises A Calderon
    Section of Allergy and Clinical Immunology, Imperial College, National Heart and Lung Institute, Dovehouse Street, London, SW3 6LY, UK
    Clin Transl Allergy 2:20. 2012
  4. doi request reprint The effectiveness of modern antihistamines for treatment of allergic rhinitis - an IPD meta-analysis of 140,853 patients
    Ralph Mosges
    Institute of Medical Statistics, Informatics and Epidemiology IMSIE, University of Cologne, Cologne, Germany
    Allergol Int 62:215-22. 2013
  5. pmc Liposomes: a new non-pharmacological therapy concept for seasonal-allergic-rhinoconjunctivitis
    M Bohm
    Institute of Medical Statistics, Informatics and Epidemiology IMSIE, University of Cologne, 50924, Cologne, Germany
    Eur Arch Otorhinolaryngol 269:495-502. 2012
  6. doi request reprint The effectiveness of levocetirizine in comparison with loratadine in treatment of allergic rhinitis--a meta-analysis
    Ralph Mosges
    Institute of Medical Statistics, Informatics and Epidemiology IMSIE, University of Cologne, Cologne, Germany
    Allergol Int 60:541-6. 2011
  7. ncbi request reprint [The RHINASTHMA-Quality of Life Scale German Adapted Version: validation of a new disease specific quality of life scale for patients suffering from allergic rhinitis and bronchial hyperreactivity]
    R Mosges
    Institut für Medizinische Statistik, Informatik und Epidemiologie der Universität zu Köln
    HNO 55:357-64. 2007
  8. doi request reprint Efficacy and safety of mometasone furoate nasal spray in the treatment of chronic rhinosinusitis
    R Mosges
    University of Cologne, Institute of Medical Statistics, Informatics and Epidemiology, Medical Faculty, University at Cologne, 50924 Cologne, Germany
    Adv Ther 28:238-49. 2011
  9. ncbi request reprint Safety of ultra-rush titration of sublingual immunotherapy in asthmatic children with tree-pollen allergy
    Ralph Mosges
    Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne, Cologne, Germany
    Pediatr Allergy Immunol 21:1135-8. 2010
  10. ncbi request reprint Topical treatment of rhinosinusitis with fusafungine nasal spray. A double-blind, placebo-controlled, parallel-group study in 20 patients
    Ralph Mosges
    Institut für Medizinische Statistik, Informatik und Epidemiologie, Medizinische Fakultat, Universitat zu Koln, Lindenburger Allee 42, 50931 Koln, Germany
    Arzneimittelforschung 52:877-83. 2002

Collaborators

  • Reinhard Klingel
  • Julia Vent
  • M Hellmich
  • H P Zenner
  • Andrea Eichel
  • Rainer K Weber
  • K Hormann
  • Desiderio Passali
  • M Schmidt
  • H Scherer
  • W Zidek
  • L Klimek
  • J Köberlein
  • Bodo Niggemann
  • H Scholz
  • Ulrich Wahn
  • G Rasp
  • P G Holt
  • Nils Achilles
  • M Bohm
  • Phillipp Maximilian Eichen
  • C Hahn
  • Moises A Calderon
  • Kristina E Hermelingmeier
  • Andreas Koop
  • Bastian Himpe
  • Volker König
  • Rainer Kirchner
  • S Allekotte
  • Jean Bousquet
  • Antonio Nieto
  • G Avgitidou
  • Jocelyne Just
  • Johannes C Virchow
  • Hans J Malling
  • Giovanni Pajno
  • Claus Bachert
  • E el Hassan
  • Lars Jacobsen
  • Stephen R Durham
  • Anthony Frew
  • Peter Eng
  • Jan Lotvall
  • Rudolph Valenta
  • Erkka Valovirta
  • Aziz Sheikh
  • Albrecht Bufe
  • Walter G Canonica
  • Giovanni Passalacqua
  • Emilio Alvarez-Cuesta
  • Alain Didier
  • Ronald Dahl
  • Glenis Scadding
  • Sabina Rak
  • Victoria Cardona
  • Marianne van Hage
  • Roy Gerth van Wijk
  • Carmen Moreno
  • Nikolaos Papadopoulos
  • Eva M Varga
  • Cezmi Akdis
  • Marek Jutel
  • Jörg Kleine-Tebbe
  • Gabriela Senti
  • Pascal Demoly
  • Antonella Muraro
  • Oliver Pfaar
  • Carmen Vidal
  • Montserrat Fernandez-Rivas
  • Beatrice Bilo
  • Gianenrico Senna
  • Barbara Bohle
  • Christine P Heubach

Detail Information

Publications36

  1. pmc Treatment of acute otitis externa with ciprofloxacin otic 0.2% antibiotic ear solution
    R Mosges
    Institute of Medical Statistics, Informatics and Epidemiology, Faculty of Medicine, University of Cologne, Germany
    Ther Clin Risk Manag 7:325-36. 2011
    ..This systematic review compares the efficacy of treatment using a ciprofloxacin 0.2% solution with other therapeutic options...
  2. pmc Tolerability and effects on quality of life of liposomal nasal spray treatment compared to nasal ointment containing dexpanthenol or isotonic NaCl spray in patients with rhinitis sicca
    C Hahn
    Institute of Medical Statistics, Informatics and Epidemiology IMSIE, University of Cologne, 50924 Cologne, Germany
    Eur Arch Otorhinolaryngol 270:2465-72. 2013
    ..LipoNasal therefore constitutes a good treatment for patients suffering from dry nose...
  3. pmc EAACI: A European Declaration on Immunotherapy. Designing the future of allergen specific immunotherapy
    Moises A Calderon
    Section of Allergy and Clinical Immunology, Imperial College, National Heart and Lung Institute, Dovehouse Street, London, SW3 6LY, UK
    Clin Transl Allergy 2:20. 2012
    ....
  4. doi request reprint The effectiveness of modern antihistamines for treatment of allergic rhinitis - an IPD meta-analysis of 140,853 patients
    Ralph Mosges
    Institute of Medical Statistics, Informatics and Epidemiology IMSIE, University of Cologne, Cologne, Germany
    Allergol Int 62:215-22. 2013
    ..The prevalence is increasing. The aim of this study was to analyse the correlation between the severity of allergic rhinitis and an adequate treatment dose of modern oral antihistamines...
  5. pmc Liposomes: a new non-pharmacological therapy concept for seasonal-allergic-rhinoconjunctivitis
    M Bohm
    Institute of Medical Statistics, Informatics and Epidemiology IMSIE, University of Cologne, 50924, Cologne, Germany
    Eur Arch Otorhinolaryngol 269:495-502. 2012
    ..This study indicates that liposomal-based treatment for SAR may be a comparable alternative to cromoglycate therapy. Further studies are needed to verify these findings...
  6. doi request reprint The effectiveness of levocetirizine in comparison with loratadine in treatment of allergic rhinitis--a meta-analysis
    Ralph Mosges
    Institute of Medical Statistics, Informatics and Epidemiology IMSIE, University of Cologne, Cologne, Germany
    Allergol Int 60:541-6. 2011
    ..Only double-blind, placebo-controlled (DBPC) studies involving monotherapy with the active substances levocetirizine and loratadine were included in the meta-analysis...
  7. ncbi request reprint [The RHINASTHMA-Quality of Life Scale German Adapted Version: validation of a new disease specific quality of life scale for patients suffering from allergic rhinitis and bronchial hyperreactivity]
    R Mosges
    Institut für Medizinische Statistik, Informatik und Epidemiologie der Universität zu Köln
    HNO 55:357-64. 2007
    ..The aim of our study was to create a valid version of this questionnaire adapted for use with German-speaking subjects...
  8. doi request reprint Efficacy and safety of mometasone furoate nasal spray in the treatment of chronic rhinosinusitis
    R Mosges
    University of Cologne, Institute of Medical Statistics, Informatics and Epidemiology, Medical Faculty, University at Cologne, 50924 Cologne, Germany
    Adv Ther 28:238-49. 2011
    ..This study evaluated the efficacy and safety of mometasone furoate nasal spray (MFNS) in patients with chronic sinusitis...
  9. ncbi request reprint Safety of ultra-rush titration of sublingual immunotherapy in asthmatic children with tree-pollen allergy
    Ralph Mosges
    Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne, Cologne, Germany
    Pediatr Allergy Immunol 21:1135-8. 2010
    ..Neither anaphylactic shock nor else serious systemic reactions to the study drug occurred. No serious adverse event assessed by the investigator as related to study drug treatment was reported...
  10. ncbi request reprint Topical treatment of rhinosinusitis with fusafungine nasal spray. A double-blind, placebo-controlled, parallel-group study in 20 patients
    Ralph Mosges
    Institut für Medizinische Statistik, Informatik und Epidemiologie, Medizinische Fakultat, Universitat zu Koln, Lindenburger Allee 42, 50931 Koln, Germany
    Arzneimittelforschung 52:877-83. 2002
    ..0342). Side effects such as reactions at the application site mainly occurred in patients in the placebo group, who rated tolerability markedly worse than patients taking fusafungine (p = 0.0304; patient diaries, p = 0.0170)...
  11. doi request reprint [Hemorrhage rates following coblation tonsillectomy. A meta-analysis of published trials]
    R Mosges
    Institut für Medizinische Statistik, Informatik und Epidemiologie IMSIE, Universitat zu Koln, Kerpener Str 62, 50924, Koln, Deutschland
    HNO 58:799-805. 2010
    ..Hemorrhage ranks among its serious postoperative complications. In this systematic review, we analyze hemorrhage following tonsillectomies performed using coblation technique...
  12. ncbi request reprint Assessment of the antiobstructive effect of fexofenadine on nasal allergy challenge in patients with seasonal allergic rhinitis
    Ralph Mosges
    Institute of Medical Statistics, Informatics and Epidemiology, University Hospital Cologne, Germany
    Asian Pac J Allergy Immunol 27:181-90. 2009
    ..041). In this double-blind, placebo-controlled trial, subjective patient ratings as well as objective investigator assessments demonstrate the anti-obstructive effect of fexofenadine in nasal allergen challenge...
  13. ncbi request reprint Comparison of the biological activity of the most common sublingual allergen solutions made by two European manufacturers
    Ralph Mosges
    Institute of Medical Statistics, Informatics, and Epidemiology, Medical Faculty, University of Cologne, Cologne, Germany
    Int Arch Allergy Immunol 139:325-9. 2006
    ..What is still lacking is a 'conversion rate' between the biological activities of different allergen solutions to determine the one with the higher concentration...
  14. doi request reprint Rheopheresis for idiopathic sudden hearing loss: results from a large prospective, multicenter, randomized, controlled clinical trial
    Ralph Mosges
    Institute of Medical Statistics, Informatics und Epidemiology, University of Cologne, Lindenburger Allee 42, 50931, Cologne, Germany
    Eur Arch Otorhinolaryngol 266:943-53. 2009
    ..Also, this may be a second line treatment option for patients refractory to i.v. corticosteroids or hemodilution...
  15. doi request reprint Quality of life in patients with idiopathic sudden hearing loss: comparison of different therapies using the Medical Outcome Short Form (36) Health Survey questionnaire
    Ralph Mosges
    Institute for Medical Statistics, Informatics and Epidemiology, University of Cologne, Cologne, Germany
    Otol Neurotol 29:769-75. 2008
    ..Quality of life (QoL) can provide helpful additional information when selecting the most appropriate therapy within current options...
  16. doi request reprint A meta-analysis of the efficacy of quinolone containing otics in comparison to antibiotic-steroid combination drugs in the local treatment of otitis externa
    R Mosges
    Institute of Medical Statistics, Informatics and Epidemiology, Faculty of Medicine, University of Cologne, Germany
    Curr Med Res Opin 27:2053-60. 2011
    ..The term otitis externa denotes the inflammation of the external auditory canal and can be treated locally in the form of monotherapy or a combination drug...
  17. doi request reprint [Allergic rhinitis and sinusitis--more than only a coincidence]
    R Mosges
    Institut für Medizinische Statistik, Informatik und Epidemiologie IMSIE, Koln
    Dtsch Med Wochenschr 133:S84-7. 2008
  18. doi request reprint Dexamethasone phosphate in antibiotic ear drops for the treatment of acute bacterial otitis externa
    Ralph Mosges
    Institute of Medical Statistics, Informatics and Epidemiology, Faculty of Medicine, University of Cologne, Germany
    Curr Med Res Opin 24:2339-47. 2008
    ..1% (PN+Dx) otic solution with polymyxin sulfate 7500 IU/neomycin sulfate 3500 IU (PN-Dx) in patients with acute bacterial otitis externa (AOE), in order to determine the possible benefit of the addition of dexamethasone...
  19. ncbi request reprint [Otitis externa]
    R Mosges
    Institut für Med Statistik, Informatik und Epidemiologie, Med Fakultät, Universitat zu Koln
    MMW Fortschr Med 150:41-3. 2008
  20. ncbi request reprint Sublingual immunotherapy in pollen-induced seasonal rhinitis and conjunctivitis: a randomized controlled trial
    R Mosges
    IMSIE Klinikum der Universität zu Köln, D 50924 Cologne, Germany
    Acta Dermatovenerol Alp Pannonica Adriat 16:143-8. 2007
    ..Sublingual immunotherapy (SLIT) is a recognized and safe treatment for allergic rhinitis and conjunctivitis. The aim was to evaluate the efficacy and safety of tablets for grass and rye pollen- induced rhinitis and conjunctivitis...
  21. ncbi request reprint [New generation antihistamines as monotherapy or in combination. What is the relevance for daily clinical routine for allergic rhinoconjunctivitis]
    R Mosges
    Institut für Medizinische Statistik, Informatik und Epidemiologie der Universität zu Köln IMSIE, Kerpener Str 62, 50937, Koln, Deutschland
    HNO 55:457-64. 2007
    ..Furthermore, it has been shown that improved clinical efficacy can be attained with an increased dosage of 20 mg daily in comparison to the usual dosage of 10 mg/day without increasing the rate of side effects...
  22. pmc Hemorrhage rate after coblation tonsillectomy: a meta-analysis of published trials
    Ralph Mosges
    Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne, 50924 Cologne, Germany
    Eur Arch Otorhinolaryngol 268:807-16. 2011
    ..1% found in this meta-analysis shows that coblation is a safe and effective technique for tonsillectomies with a secondary bleeding rate similar to what is reported for comparable techniques such as bipolar diathermia...
  23. ncbi request reprint Topical treatment of acute otitis externa: clinical comparison of an antibiotics ointment alone or in combination with hydrocortisone acetate
    Ralph Mosges
    Institute of Medical Statistics, Informatics and Epidemiology, Faculty of Medicine, University of Cologne, Lindenburger Allee 42, 50931 Cologne, Germany
    Eur Arch Otorhinolaryngol 264:1087-94. 2007
    ..No serious adverse events occurred. Both ointments are effective and safe in the topical treatment of AOE. Hydrocortisone acetate combined with the antibiotics improved individual symptoms better as did the steroid-free ointment...
  24. doi request reprint [Survey of sensory perception and patients' subjective assessment of the application of nasal sprays - the nasal-spray-sensoric-scale]
    Ralph Mosges
    Institut für Medizinische Statistik, Informatik und Epidemiologie IMSIE, Universitätsklinikum Köln, Koln
    Laryngorhinootologie 88:587-91. 2009
    ..Three nasal sprays were tested and the questionnaire was used to estimate sensory hedonicity. Finally, the questionnaire was improved and can now serve as a standardized means to measure nasal sensory perceptions...
  25. doi request reprint Nasal saline irrigations for the symptoms of acute and chronic rhinosinusitis
    Nils Achilles
    Institute of Medical Statistics, Informatics and Epidemiology, University Hospital of Cologne, Cologne, Germany
    Curr Allergy Asthma Rep 13:229-35. 2013
    ..5 %). Conclusive proof of the efficacy of SNI in the treatment of ARS is still pending. In CRS, SNI is one of the cornerstones of treatment...
  26. doi request reprint A prospective, controlled study of SNS01 (ectoine nasal spray) compared to BNO-101 (phytotherapeutic dragées) in patients with acute rhinosinusitis
    Andrea Eichel
    Institute of Medical Statistics, Informatics and Epidemiology, Faculty of Medicine, University of Cologne, Cologne, Germany
    Curr Med Res Opin 29:739-46. 2013
    ....
  27. doi request reprint Rheopheresis for sudden sensorineural hearing loss
    Reinhard Klingel
    Apheresis Research Institute, Cologne, Germany
    Atheroscler Suppl 10:102-6. 2009
    ..Patients can apply for individual reimbursement or must pay the cost for the treatment. Refractory patients hopefully will profit by growing experiences...
  28. doi request reprint Glycerol lidocaine eardrops for the treatment of acute abacterial otitis externa
    Ralph Mosges
    Institute of Medical Statistics, Informatics and Epidemiology IMSIE, University Hospital of Cologne, Germany
    Arzneimittelforschung 60:427-31. 2010
    ..The advantage regarding efficacy of this combination compared with glycerol eardrops must be demonstrated in an adequately powered clinical trial...
  29. ncbi request reprint Nucleoplasty, a minimally invasive procedure for disc decompression: a systematic review and meta-analysis of published clinical studies
    Phillipp Maximilian Eichen
    Institute of Medical Statistics, Informatics and Epidemiology IMSIE, University Hospital of Cologne, Germany
    Pain Physician 17:E149-73. 2014
    ..In the process, the central question was to statistically determine whether, and to what extent, nucleoplasty can positively affect pain relief and functional mobility as well as lower the complication rate...
  30. pmc Characterisation of patients receiving moxifloxacin for acute bacterial rhinosinusitis in clinical practice: results from an international, observational cohort study
    Ralph Mosges
    University Hospital Cologne, Cologne, Germany
    PLoS ONE 8:e61927. 2013
    ..Moxifloxacin was an effective and well-tolerated treatment option in the overall population. Registration: ClinicalTrials.gov Identifier: NCT00930488...
  31. ncbi request reprint Why do we treat allergies with antibiotics?
    Ralph Mosges
    IMSIE, Klinikum of the University of Koln, Cologne, Germany
    Curr Opin Allergy Clin Immunol 6:144-5. 2006
  32. ncbi request reprint [Sublingual immunotherapy (SLIT) in the allergologist's practice]
    Ralph Mosges
    Institut für Medizinische Statistik, Informatik und Epidemiologie der Universität zu Köln
    MMW Fortschr Med 150:79-84. 2008
  33. ncbi request reprint Sublingual specific immunotherapy
    Ralph Mosges
    Institute of Medical Statistics, Informatics and Epidemiology, Cologne University Hospital, Cologne 50931, Germany
    Discov Med 10:348-54. 2010
    ..The complexity of the treatment of this condition mandates expert care by an experienced allergologist...
  34. doi request reprint Nasal irrigation as an adjunctive treatment in allergic rhinitis: a systematic review and meta-analysis
    Kristina E Hermelingmeier
    Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne, Cologne, Germany
    Am J Rhinol Allergy 26:e119-25. 2012
    ..To date, however, no systematic review or meta-analysis exists showing the influence of SNI on allergic rhinitis (AR). This study aimed to establish the impact of SNI on symptoms of AR in different patient groups...
  35. pmc On the sustainability of guideline implementation
    Juliane Köberlein
    From the 1Institute of Medical Statistics, Informatics and Epidemiology, Faculty of Medicine, University of Cologne, Cologne, Germany 2Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne Medical Center, Cologne, Germany
    World Allergy Organ J 3:258-61. 2010
    ..The objective of the present analysis was to estimate the compliance with guidelines among ear, nose and throat (ENT) specialists and general practitioners...
  36. ncbi request reprint The use of handheld computers in clinical trials
    Andreas Koop
    Institute for Medical Statistics, Informatics, and Epidemiology, University of Cologne, Cologne, Germany
    Control Clin Trials 23:469-80. 2002
    ..We conclude that mobile devices are very useful in most cases, especially when design and software validation aspects have been taken into account...