Research Topics
| Ralph MosgesSummaryCountry: Germany Publications
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Detail Information
Publications
Liposomes: a new non-pharmacological therapy concept for seasonal-allergic-rhinoconjunctivitisM Bohm
Institute of Medical Statistics, Informatics and Epidemiology IMSIE, University of Cologne, 50924, Cologne, Germany
Eur Arch Otorhinolaryngol 269:495-502. 2012..This study indicates that liposomal-based treatment for SAR may be a comparable alternative to cromoglycate therapy. Further studies are needed to verify these findings...
The effectiveness of levocetirizine in comparison with loratadine in treatment of allergic rhinitis--a meta-analysisRalph Mosges
Institute of Medical Statistics, Informatics and Epidemiology IMSIE, University of Cologne, Cologne, Germany
Allergol Int 60:541-6. 2011..Only double-blind, placebo-controlled (DBPC) studies involving monotherapy with the active substances levocetirizine and loratadine were included in the meta-analysis...- Quality of life in patients with idiopathic sudden hearing loss: comparison of different therapies using the Medical Outcome Short Form (36) Health Survey questionnaireRalph Mosges
Institute for Medical Statistics, Informatics and Epidemiology, University of Cologne, Cologne, Germany
Otol Neurotol 29:769-75. 2008..Quality of life (QoL) can provide helpful additional information when selecting the most appropriate therapy within current options... - Rheopheresis for idiopathic sudden hearing loss: results from a large prospective, multicenter, randomized, controlled clinical trialRalph Mosges
Institute of Medical Statistics, Informatics und Epidemiology, University of Cologne, Lindenburger Allee 42, 50931, Cologne, Germany
Eur Arch Otorhinolaryngol 266:943-53. 2009..Also, this may be a second line treatment option for patients refractory to i.v. corticosteroids or hemodilution... 
Safety of ultra-rush titration of sublingual immunotherapy in asthmatic children with tree-pollen allergyRalph Mosges
Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne, Cologne, Germany
Pediatr Allergy Immunol 21:1135-8. 2010..Neither anaphylactic shock nor else serious systemic reactions to the study drug occurred. No serious adverse event assessed by the investigator as related to study drug treatment was reported...- Hemorrhage rate after coblation tonsillectomy: a meta-analysis of published trialsRalph Mosges
Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne, 50924 Cologne, Germany
Eur Arch Otorhinolaryngol 268:807-16. 2011..1% found in this meta-analysis shows that coblation is a safe and effective technique for tonsillectomies with a secondary bleeding rate similar to what is reported for comparable techniques such as bipolar diathermia... - Assessment of the antiobstructive effect of fexofenadine on nasal allergy challenge in patients with seasonal allergic rhinitisRalph Mosges
Institute of Medical Statistics, Informatics and Epidemiology, University Hospital Cologne, Germany
Asian Pac J Allergy Immunol 27:181-90. 2009..041). In this double-blind, placebo-controlled trial, subjective patient ratings as well as objective investigator assessments demonstrate the anti-obstructive effect of fexofenadine in nasal allergen challenge... - [Hemorrhage rates following coblation tonsillectomy. A meta-analysis of published trials]R Mosges
Institut für Medizinische Statistik, Informatik und Epidemiologie IMSIE, Universitat zu Koln, Kerpener Str 62, 50924, Koln, Deutschland
HNO 58:799-805. 2010..Hemorrhage ranks among its serious postoperative complications. In this systematic review, we analyze hemorrhage following tonsillectomies performed using coblation technique... - Efficacy and safety of mometasone furoate nasal spray in the treatment of chronic rhinosinusitisR Mosges
University of Cologne, Institute of Medical Statistics, Informatics and Epidemiology, Medical Faculty, University at Cologne, 50924 Cologne, Germany
Adv Ther 28:238-49. 2011..This study evaluated the efficacy and safety of mometasone furoate nasal spray (MFNS) in patients with chronic sinusitis... - [Allergic rhinitis and sinusitis--more than only a coincidence]R Mosges
Institut für Medizinische Statistik, Informatik und Epidemiologie IMSIE, Koln
Dtsch Med Wochenschr 133:S84-7. 2008 - Dexamethasone phosphate in antibiotic ear drops for the treatment of acute bacterial otitis externaRalph Mosges
Institute of Medical Statistics, Informatics and Epidemiology, Faculty of Medicine, University of Cologne, Germany
Curr Med Res Opin 24:2339-47. 2008..1% (PN+Dx) otic solution with polymyxin sulfate 7500 IU/neomycin sulfate 3500 IU (PN-Dx) in patients with acute bacterial otitis externa (AOE), in order to determine the possible benefit of the addition of dexamethasone... - Topical treatment of rhinosinusitis with fusafungine nasal spray. A double-blind, placebo-controlled, parallel-group study in 20 patientsRalph Mosges
Institut für Medizinische Statistik, Informatik und Epidemiologie, Medizinische Fakultat, Universitat zu Koln, Lindenburger Allee 42, 50931 Koln, Germany
Arzneimittelforschung 52:877-83. 2002..0342). Side effects such as reactions at the application site mainly occurred in patients in the placebo group, who rated tolerability markedly worse than patients taking fusafungine (p = 0.0304; patient diaries, p = 0.0170)... - Comparison of the biological activity of the most common sublingual allergen solutions made by two European manufacturersRalph Mosges
Institute of Medical Statistics, Informatics, and Epidemiology, Medical Faculty, University of Cologne, Cologne, Germany
Int Arch Allergy Immunol 139:325-9. 2006..What is still lacking is a 'conversion rate' between the biological activities of different allergen solutions to determine the one with the higher concentration... - A meta-analysis of the efficacy of quinolone containing otics in comparison to antibiotic-steroid combination drugs in the local treatment of otitis externaR Mosges
Institute of Medical Statistics, Informatics and Epidemiology, Faculty of Medicine, University of Cologne, Germany
Curr Med Res Opin 27:2053-60. 2011..The term otitis externa denotes the inflammation of the external auditory canal and can be treated locally in the form of monotherapy or a combination drug... - [The RHINASTHMA-Quality of Life Scale German Adapted Version: validation of a new disease specific quality of life scale for patients suffering from allergic rhinitis and bronchial hyperreactivity]R Mosges
Institut für Medizinische Statistik, Informatik und Epidemiologie der Universität zu Köln
HNO 55:357-64. 2007..The aim of our study was to create a valid version of this questionnaire adapted for use with German-speaking subjects... - [New generation antihistamines as monotherapy or in combination. What is the relevance for daily clinical routine for allergic rhinoconjunctivitis]R Mosges
Institut für Medizinische Statistik, Informatik und Epidemiologie der Universität zu Köln IMSIE, Kerpener Str 62, 50937, Koln, Deutschland
HNO 55:457-64. 2007..Furthermore, it has been shown that improved clinical efficacy can be attained with an increased dosage of 20 mg daily in comparison to the usual dosage of 10 mg/day without increasing the rate of side effects... - Sublingual immunotherapy in pollen-induced seasonal rhinitis and conjunctivitis: a randomized controlled trialR Mosges
IMSIE Klinikum der Universität zu Köln, D 50924 Cologne, Germany
Acta Dermatovenerol Alp Panonica Adriat 16:143-8. 2007..Sublingual immunotherapy (SLIT) is a recognized and safe treatment for allergic rhinitis and conjunctivitis. The aim was to evaluate the efficacy and safety of tablets for grass and rye pollen- induced rhinitis and conjunctivitis... - [Otitis externa]R Mosges
Institut für Med Statistik, Informatik und Epidemiologie, Med Fakultät, Universitat zu Koln
MMW Fortschr Med 150:41-3. 2008 - Topical treatment of acute otitis externa: clinical comparison of an antibiotics ointment alone or in combination with hydrocortisone acetateRalph Mosges
Institute of Medical Statistics, Informatics and Epidemiology, Faculty of Medicine, University of Cologne, Lindenburger Allee 42, 50931 Cologne, Germany
Eur Arch Otorhinolaryngol 264:1087-94. 2007..No serious adverse events occurred. Both ointments are effective and safe in the topical treatment of AOE. Hydrocortisone acetate combined with the antibiotics improved individual symptoms better as did the steroid-free ointment... - Nasal saline irrigations for the symptoms of acute and chronic rhinosinusitisNils Achilles
Institute of Medical Statistics, Informatics and Epidemiology, University Hospital of Cologne, Cologne, Germany
Curr Allergy Asthma Rep 13:229-35. 2013..5 %). Conclusive proof of the efficacy of SNI in the treatment of ARS is still pending. In CRS, SNI is one of the cornerstones of treatment... - [Survey of sensory perception and patients' subjective assessment of the application of nasal sprays - the nasal-spray-sensoric-scale]Ralph Mosges
Institut für Medizinische Statistik, Informatik und Epidemiologie IMSIE, Universitätsklinikum Köln, Koln
Laryngorhinootologie 88:587-91. 2009..Three nasal sprays were tested and the questionnaire was used to estimate sensory hedonicity. Finally, the questionnaire was improved and can now serve as a standardized means to measure nasal sensory perceptions... - Why do we treat allergies with antibiotics?Ralph Mosges
IMSIE, Klinikum of the University of Koln, Cologne, Germany
Curr Opin Allergy Clin Immunol 6:144-5. 2006 - Glycerol lidocaine eardrops for the treatment of acute abacterial otitis externaRalph Mosges
Institute of Medical Statistics, Informatics and Epidemiology IMSIE, University Hospital of Cologne, Germany
Arzneimittelforschung 60:427-31. 2010..The advantage regarding efficacy of this combination compared with glycerol eardrops must be demonstrated in an adequately powered clinical trial... - Rheopheresis for sudden sensorineural hearing lossReinhard Klingel
Apheresis Research Institute, Cologne, Germany
Atheroscler Suppl 10:102-6. 2009..Patients can apply for individual reimbursement or must pay the cost for the treatment. Refractory patients hopefully will profit by growing experiences... - [Sublingual immunotherapy (SLIT) in the allergologist's practice]Ralph Mosges
Institut für Medizinische Statistik, Informatik und Epidemiologie der Universität zu Köln
MMW Fortschr Med 150:79-84. 2008 - Sublingual specific immunotherapyRalph Mosges
Institute of Medical Statistics, Informatics and Epidemiology, Cologne University Hospital, Cologne 50931, Germany
Discov Med 10:348-54. 2010..The complexity of the treatment of this condition mandates expert care by an experienced allergologist... - On the sustainability of guideline implementationJuliane Köberlein
From the 1Institute of Medical Statistics, Informatics and Epidemiology, Faculty of Medicine, University of Cologne, Cologne, Germany 2Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne Medical Center, Cologne, Germany
World Allergy Organ J 3:258-61. 2010..The objective of the present analysis was to estimate the compliance with guidelines among ear, nose and throat (ENT) specialists and general practitioners... - The use of handheld computers in clinical trialsAndreas Koop
Institute for Medical Statistics, Informatics, and Epidemiology, University of Cologne, Cologne, Germany
Control Clin Trials 23:469-80. 2002..We conclude that mobile devices are very useful in most cases, especially when design and software validation aspects have been taken into account... - Nasal irrigation as an adjunctive treatment in allergic rhinitis: a systematic review and meta-analysisKristina E Hermelingmeier
Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne, Cologne, Germany
Am J Rhinol Allergy 26:e119-25. 2012..To date, however, no systematic review or meta-analysis exists showing the influence of SNI on allergic rhinitis (AR). This study aimed to establish the impact of SNI on symptoms of AR in different patient groups...