Michael Mormann

Summary

Country: Germany

Publications

  1. ncbi Electron capture dissociation of O-glycosylated peptides: radical site-induced fragmentation of glycosidic bonds
    Michael Mormann
    Institute for Medical Physics and Biophysics, Biomedical Analysis Department, University of Munster, Robert Koch Str 31, D 48149 Munster, Germany
    Eur J Mass Spectrom (Chichester, Eng) 11:497-511. 2005
  2. ncbi Uncommon membrane distribution of Shiga toxin glycosphingolipid receptors in toxin-sensitive human glomerular microvascular endothelial cells
    Josefine Betz
    Institute for Hygiene, University of Munster, D 48149 Munster, Germany
    Biol Chem 393:133-47. 2012
  3. ncbi On the structural diversity of Shiga toxin glycosphingolipid receptors in lymphoid and myeloid cells determined by nanoelectrospray ionization tandem mass spectrometry
    Petra Hoffmann
    Institute of Hygiene, University of Munster, D 48149 Munster, Germany
    Rapid Commun Mass Spectrom 24:2295-304. 2010
  4. ncbi Sequencing of O-glycopeptides derived from an S-layer glycoprotein of Geobacillus stearothermophilus NRS 2004/3a containing up to 51 monosaccharide residues at a single glycosylation site by fourier transform ion cyclotron resonance infrared multiphoton d
    Laura Bindila
    Institute for Medical Physics and Biophysics, University of Munster, Robert Koch Strasse 31, D 48149 Munster, Germany
    Anal Chem 79:3271-9. 2007
  5. ncbi The human H3N2 influenza viruses A/Victoria/3/75 and A/Hiroshima/52/2005 preferentially bind to α2-3-sialylated monosialogangliosides with fucosylated poly-N-acetyllactosaminyl chains
    Iris Meisen
    Institute for Hygiene, Biophysics, University of Munster, D 48149 Munster, Germany
    Glycobiology 22:1055-76. 2012
  6. ncbi Shiga toxin glycosphingolipid receptor expression and toxin susceptibility of human pancreatic ductal adenocarcinomas of differing origin and differentiation
    Wiebke Storck
    Institute for Hygiene, University of Munster, D 48149 Munster, Germany
    Biol Chem 393:785-99. 2012
  7. ncbi Promiscuous Shiga toxin 2e and its intimate relationship to Forssman
    Johannes Muthing
    Institute for Hygiene, University of Munster, D 48149 Munster, Germany
    Glycobiology 22:849-62. 2012
  8. ncbi Improvement of electron capture efficiency by resonant excitation
    Michael Mormann
    Institute for Medical Physics and Biophysics, Biomedical Analysis Department, University of Munster, Robert Koch Str 31, D 48149 Munster, Germany
    Rapid Commun Mass Spectrom 17:2208-14. 2003
  9. ncbi The human CASQ2 mutation K206N is associated with hyperglycosylation and altered cellular calcium handling
    Uwe Kirchhefer
    Institut fur Pharmakologie und Toxikologie, Universitatsklinikum Munster, Domagkstr 12, 48149 Munster, Germany
    J Mol Cell Cardiol 49:95-105. 2010
  10. ncbi Direct coupling of high-performance thin-layer chromatography with UV spectroscopy and IR-MALDI orthogonal TOF MS for the analysis of cyanobacterial toxins
    Iris Meisen
    Institute for Hygiene, University of Munster, Robert Koch Strasse 41, D 48149 Munster, Germany
    Anal Chem 81:3858-66. 2009

Collaborators

Detail Information

Publications17

  1. ncbi Electron capture dissociation of O-glycosylated peptides: radical site-induced fragmentation of glycosidic bonds
    Michael Mormann
    Institute for Medical Physics and Biophysics, Biomedical Analysis Department, University of Munster, Robert Koch Str 31, D 48149 Munster, Germany
    Eur J Mass Spectrom (Chichester, Eng) 11:497-511. 2005
    ..The different sugar core types exhibit different fragmentation patterns driven by the stability of the resulting fragments allowing the discrimination of isomeric glycans...
  2. ncbi Uncommon membrane distribution of Shiga toxin glycosphingolipid receptors in toxin-sensitive human glomerular microvascular endothelial cells
    Josefine Betz
    Institute for Hygiene, University of Munster, D 48149 Munster, Germany
    Biol Chem 393:133-47. 2012
    ..Our finding opens new questions on the microdomain association of Stx receptors and the functional role of GSLs in the membrane assembly of GMVECs...
  3. ncbi On the structural diversity of Shiga toxin glycosphingolipid receptors in lymphoid and myeloid cells determined by nanoelectrospray ionization tandem mass spectrometry
    Petra Hoffmann
    Institute of Hygiene, University of Munster, D 48149 Munster, Germany
    Rapid Commun Mass Spectrom 24:2295-304. 2010
    ....
  4. ncbi Sequencing of O-glycopeptides derived from an S-layer glycoprotein of Geobacillus stearothermophilus NRS 2004/3a containing up to 51 monosaccharide residues at a single glycosylation site by fourier transform ion cyclotron resonance infrared multiphoton d
    Laura Bindila
    Institute for Medical Physics and Biophysics, University of Munster, Robert Koch Strasse 31, D 48149 Munster, Germany
    Anal Chem 79:3271-9. 2007
    ..The microheterogeneity of carbohydrate chains at the same glycosylation site, containing largely rhamnose, could have been reliably assessed...
  5. ncbi The human H3N2 influenza viruses A/Victoria/3/75 and A/Hiroshima/52/2005 preferentially bind to α2-3-sialylated monosialogangliosides with fucosylated poly-N-acetyllactosaminyl chains
    Iris Meisen
    Institute for Hygiene, Biophysics, University of Munster, D 48149 Munster, Germany
    Glycobiology 22:1055-76. 2012
    ..In addition, our results pose new questions on the biological and clinical relevance of this unexpected specificity of a subtype of influenza A viruses...
  6. ncbi Shiga toxin glycosphingolipid receptor expression and toxin susceptibility of human pancreatic ductal adenocarcinomas of differing origin and differentiation
    Wiebke Storck
    Institute for Hygiene, University of Munster, D 48149 Munster, Germany
    Biol Chem 393:785-99. 2012
    ....
  7. ncbi Promiscuous Shiga toxin 2e and its intimate relationship to Forssman
    Johannes Muthing
    Institute for Hygiene, University of Munster, D 48149 Munster, Germany
    Glycobiology 22:849-62. 2012
    ....
  8. ncbi Improvement of electron capture efficiency by resonant excitation
    Michael Mormann
    Institute for Medical Physics and Biophysics, Biomedical Analysis Department, University of Munster, Robert Koch Str 31, D 48149 Munster, Germany
    Rapid Commun Mass Spectrom 17:2208-14. 2003
    ..In addition to amino acid sequence information, the attachment site of the labile glycan moiety is determined, and also radical-site-induced fragmentations of the glycosidic bonds are observed...
  9. ncbi The human CASQ2 mutation K206N is associated with hyperglycosylation and altered cellular calcium handling
    Uwe Kirchhefer
    Institut fur Pharmakologie und Toxikologie, Universitatsklinikum Munster, Domagkstr 12, 48149 Munster, Germany
    J Mol Cell Cardiol 49:95-105. 2010
    ..This may then contribute to the increased propensity to trigger spontaneous Ca(2+) transients in CSQ(K206N)-expressing myocytes...
  10. ncbi Direct coupling of high-performance thin-layer chromatography with UV spectroscopy and IR-MALDI orthogonal TOF MS for the analysis of cyanobacterial toxins
    Iris Meisen
    Institute for Hygiene, University of Munster, Robert Koch Strasse 41, D 48149 Munster, Germany
    Anal Chem 81:3858-66. 2009
    ..It was successfully applied to the detection and quantification of MC LR and Nod in a spiked, processed environmental water sample...
  11. ncbi Normal silica gel and reversed phase thin-layer chromatography coupled with UV spectroscopy and IR-MALDI-o-TOF-MS for the detection of tetracycline antibiotics
    Iris Meisen
    Institute for Hygiene, University of Munster, Robert Koch Str 41, 48149 Munster, Germany
    Anal Bioanal Chem 398:2821-31. 2010
    ..An approximate detection limit of 5 ng of individual TCs in mixtures by combining RP-18W HPTLC with IR-MALDI-o-TOF-MS offers a novel timely and cost-efficient method for tracing TCs...
  12. ncbi Direct analysis of α- and β-chains of hemoglobins from mammalian blood samples by nanoESI mass spectrometry during in-capillary proteolytic digestion
    Stefanie Henning
    Institute of Medical Physics and Biophysics, University of Munster, Robert Koch Strasse 31, 48149, Munster, Germany
    Amino Acids 41:343-50. 2011
    ..The present study demonstrates that in-capillary digestion allows fast characterization and/or sequencing of hemoglobin chains directly from blood samples...
  13. ncbi Fragmentation of intra-peptide and inter-peptide disulfide bonds of proteolytic peptides by nanoESI collision-induced dissociation
    Michael Mormann
    Institute for Medical Physics und Biophysics, University of Munster, Robert Koch Str 31, 48149, Munster, Germany
    Anal Bioanal Chem 392:831-8. 2008
    ..These fragmentations are preceded by proton-induced asymmetric cleavage of the disulfide bridge giving rise to a modified cysteine containing a disulfohydryl substituent and a dehydroalanine residue on the C-S cleavage site...
  14. ncbi Analysis of oversulfation in a chondroitin sulfate oligosaccharide fraction from bovine aorta by nanoelectrospray ionization quadrupole time-of-flight and Fourier-transform ion cyclotron resonance mass spectrometry
    Michael Mormann
    Institute for Medical Physics and Biophysics, Biomedical Analysis Department, University of Munster, Munster, Germany
    J Am Soc Mass Spectrom 18:179-87. 2007
    ..Cleavage of glycosidic bonds gave rise to B- and C-type ions and their respective complementary Y- and Z-type fragment ions...
  15. ncbi Thin-layer chromatography, overlay technique and mass spectrometry: a versatile triad advancing glycosphingolipidomics
    Iris Meisen
    Institute for Hygiene, University of Munster, Munster, Germany
    Biochim Biophys Acta 1811:875-96. 2011
    ..We believe that the combinatorial approach using conventional TLC and modern mass spectrometry provides a developmental advance in exploring the glycosphingolipidome of biological material...
  16. ncbi Identification of glycoconjugates in the urine of a patient with congenital disorder of glycosylation by high-resolution mass spectrometry
    Sergey Y Vakhrushev
    Institute for Medical Physics and Biophysics, Biomedical Analysis Department, , , Germany
    Proteomics 6:983-92. 2006
    ..Taking advantage of this strategy, the number of compositions assigned to mass peaks was significantly increased in a fraction obtained from urine by size exclusion and anion exchange chromatography...
  17. ncbi Neutral glycosphingolipids in human blood: a precise mass spectrometry analysis with special reference to lipoprotein-associated Shiga toxin receptors
    Christian H Schweppe
    Institute for Hygiene, University of Munster, D 48149 Munster, Germany
    J Lipid Res 51:2282-94. 2010
    ..Our findings provide the basis for exploring the functional role of lipoprotein-associated Stx-receptors in human blood...