Research Topics
| Matthias MoehrleSummaryCountry: Germany Publications
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Detail Information
Publications
Melanoma of the ear: prognostic factors and surgical strategiesV Jahn
Department of Dermatology, University of Tuebingen Clinics, , Liebermeisterstr. 25, D-72076 Tuebingen, Germany
Br J Dermatol 154:310-8. 2006..Smaller excision margins under 3D-histological control did not carry an increased risk of local recurrence. Our results do not permit conclusions regarding the prognostic impact of SLNB for patients with melanoma of the ear...
Wavelet analysis of skin blood flow in dermatosurgery using primary closure with tensionHans Martin Häfner
Department of Dermatology, University of Tubingen, Germany
Clin Hemorheol Microcirc 47:99-109. 2011..In dermatosurgery, wounds can be closed directly without changing the microcirculatory pattern in the direct area of the wound margins...
Rapid lump examination (RLE) - a new tool for Mohs surgery?Matthias Moehrle
Universitäts Hautklinik Tuebingen, Germany
J Dtsch Dermatol Ges 9:534-8. 2011..The presented technique is the rapid direct microscopy of the surface of a specimen (lump) for a pathological examination (RLE)...
Clinical risk factors and prognostic significance of local recurrence in cutaneous melanomaM Moehrle
Department of Dermatology, Universitaetsklinikum Tuebingen, Eberhard Karls Universitaet, Liebermeisterstr 25, D 72076 Tuebingen, Germany
Br J Dermatol 151:397-406. 2004..In the literature the term 'LR' has been used in a vague and inconsistent manner that may include satellite and in-transit metastasis...
Micrometastasis of a sentinel lymph node in cutaneous melanoma is a significant prognostic factor for disease-free survival, distant-metastasis-free survival, and overall survivalM Moehrle
Department of Dermatology, Universitaetsklinikum Tuebingen, Eberhard Karls Universitaet, Tuebingen, Germany
Dermatol Surg 30:1319-28. 2004..The aim of this work was to investigate the prognostic value of detection of micrometastasis by SLNB...
[Sentinel node biopsy. What are the facts?]M Möhrle
Universitäts Hautklinik, Klinikum der Eberhard Karls Universität Tübingen
Hautarzt 56:441-7. 2005..Issues include the usefulness of highly sensitive evaluation of SN using molecular biology or cytology techniques, as well as the therapeutic impact of the SNB per se and the associated combined surgical or medical adjuvant therapies...
[Skin and sports]Matthias Möhrle
Universitäts Hautklinik Tübingen
J Dtsch Dermatol Ges 2:695-702; quiz 703. 2004
[Micrographic controlled surgery (3D-histology) in cutaneous melanoma]Matthias Möhrle
Universitäts Hautklinik, Eberhard Karls Universitat, Tubingen
J Dtsch Dermatol Ges 1:869-75. 2003..In functionally and cosmetically important areas (face, hand, foot) 3D-histology may allow reduced safety margins in other histological types of cutaneous melanoma...
[Prognostic parameters and surgical strategies for facial melanomas]M Möhrle
Universitäts Hautklinik, Universitatsklinikum Tubingen, Eberhard Karls Universitat, Tubingen
J Dtsch Dermatol Ges 1:457-63. 2003....
Conventional histology vs. three-dimensional histology in lentigo maligna melanomaM Moehrle
Department of Dermatology, Universitatsklinikum Tubingen, Germany
Br J Dermatol 154:453-9. 2006..These can be specifically excised in tumour-positive areas with smaller excision margins, and better cosmesis and function. To date there have been no controlled studies of micrographic surgery of LMM...
[Modern investigation with historical methods. Objective structured clinical examination (OSCE) of moulages]M Möhrle
Universitäts Hautklinik, Tubingen
Hautarzt 57:528-31. 2006
[3D histology: a micrographic surgical technique suitable for French dermatologists and pathologists in private and hospital practice]M Moehrle
Service de Dermatologie, , , Liebermeisterstr. 25, , Allemagne
Ann Dermatol Venereol 134:87-93. 2007
A confusing world: what to call histology of three-dimensional tumour margins?M Moehrle
Department of Dermatology, University Hospital, Eberhard Karls University, Tubingen, Germany
J Eur Acad Dermatol Venereol 21:591-5. 2007..As an added advantage, 3D histology can also be used in other medical disciplines to confirm true R0 resection of, for example, breast cancer or intestinal cancer...
[Slow infusion tumescent anaesthesia]M Moehrle
, , , Allemagne
Ann Fr Anesth Reanim 26:821-5. 2007
[3D Histology: a protocol of micrographic surgery well fitted for French dermatologists and pathologists]M Moehrle
Service de Dermatologie, Universitäts Hautklinik, Eberhard Karls Universitat, Liebermeisterstr 25, D 72076 Tubingen, Allemagne
Ann Pathol 27:163-71. 2007..We have adapted the protocol created in Germany, at the University of Tuebingen, for French pathologists and dermatologists...
Outdoor sports and skin cancerMatthias Moehrle
Department of Dermatology, University Hospital Tuebingen, Liebermeisterstr 25, D 72076 Tubingen, Germany
Clin Dermatol 26:12-5. 2008..Protective means such as avoiding training and competition with considerable sun exposure, choosing adequate clothing, and applying water-resistant sunscreen still need to be propagated in the community of outdoor sportsmen...
[Operative therapy of acral melanomas]M Möhrle
Universitäts Hautklinik Tübingen, Tubingen, Germany
Hautarzt 62:362-7. 2011..Function and cosmesis of the finger or toe are preserved. Amputation in subungual melanoma is not recommended and should be reserved only for infiltrating melanomas with affection of the bone or joint...
Is sentinel lymph node biopsy of therapeutic relevance for melanoma?M Möhrle
Department of Dermatology, Universitatsklinikum Tubingen, Eberhard Karls Universitat, Tubingen, Germany
Dermatology 209:5-13. 2004..To date, no results from prospective, randomized studies of SLNB are available...
UV exposure in carsMatthias Moehrle
Department of Dermatology, University of Tuebingen, Germany
Photodermatol Photoimmunol Photomed 19:175-81. 2003..Although people spend a significant time in cars, data on UV exposure during traveling are lacking. The aim of this study was to obtain basic information on personal UV exposure in cars...
High prevalence of seborrhoeic dermatitis on the face and scalp in mountain guidesM Moehrle
Department of Dermatology, University of Tubingen, Germany
Dermatology 201:146-7. 2000..High incidence rates of seborrhoeic dermatitis (SD) have been reported in HIV-infected individuals, indicating immunosuppression to be involved in the pathogenesis...
Bacillus subtilis spore film dosimeters in personal dosimetry for occupational solar ultraviolet exposureM Moehrle
Department of Dermatology, Eberhard Karls University, Tuebingen, Germany
Int Arch Occup Environ Health 73:575-80. 2000....
Extreme UV exposure of professional cyclistsM Moehrle
Department of Dermatology, University of Tubingen, Germany
Dermatology 201:44-5. 2000..To date there is no quantification of the UV exposure of outdoor sports professionals training and competing at high solar UV levels...
Reduction of minimal erythema dose by sweatingM Moehrle
Department of Dermatology, University of Tuebingen, Germany
Photodermatol Photoimmunol Photomed 16:260-2. 2000..The aim of the present study was to determine the influence of sweating from heat or from physical activity on the photosensitivity of the skin...
Ultraviolet exposure in the Ironman triathlonM Moehrle
Department of Dermatology, University of Tuebingen, Germany
Med Sci Sports Exerc 33:1385-6. 2001..Skin cancer is increasing worldwide and exposure to ultraviolet (UV) radiation is thought to be the most important environmental risk factor. People practicing outdoor sports are exposed to considerable amounts of UV radiation from the sun...
Does mountaineering increase the incidence of cutaneous melanoma? A hypothesis based on cancer registry dataM Moehrle
Section of Dermatologic Oncology, Department of Dermatology, Eberhard Karls University, Tubingen, Germany
Dermatology 199:201-3. 1999....
Tattoo pigment mimics positive sentinel lymph node in melanomaM Moehrle
Department of Dermatology, University of Tubingen, Germany
Dermatology 203:342-4. 2001..However, histopathological examination of the lymph nodes did not detect micrometastases. The pigmentation of the lymph nodes was due to decorative tattoos of the scapular skin...
Primary malignant melanoma arising in a cystic necrotic ovarian teratomaM Moehrle
Department of Dermatology, University of Tuebingen, Liebermeisterstr 25, 72076, Tubingen, Germany
Eur J Obstet Gynecol Reprod Biol 99:268-71. 2001..After 7 months of operation metastasis to the vertebral column occurred, 2 months later liver metastases were diagnosed. The patient died of the disease 14 months after initial diagnosis...
"Functional" surgery in subungual melanomaMatthias Moehrle
Department of Dermatology, University of Tuebingen, Tuebingen, Germany
Dermatol Surg 29:366-74. 2003..Recently, we introduced for acral melanomas, similar to lentigo maligna melanoma, limited excision and complete histology of excisional margins (three-dimensional histology)...
Continuous long-term monitoring of UV radiation in professional mountain guides reveals extremely high exposureMatthias Moehrle
Department of Dermatology, Eberhard Karls University, Tuebingen, Germany
Int J Cancer 103:775-8. 2003..These extremely high exposure values are suggestive for an increased risk of skin cancer and thorough epidemiologic studies in the collectives of professional and recreational mountaineering are required...
[Removal of ticks with scalpel or disposable razor]M Möhrle
Hautklinik der Universität Tübingen, Germany
Hautarzt 53:579-80. 2002
Is subungual melanoma related to trauma?M Möhrle
Department of Dermatology, University of Tubingen, Germany
Dermatology 204:259-61. 2002..Squamous cell carcinoma is known to occur in sites of chronic trauma. Trauma could be an etiologic factor in subungual melanoma as well...
Cerebriform giant melanocytic nevus of the scalp: report of two cases with different surgical approachesMatthias Moehrle
Department of Dermatology, Eberhard Karls University, Tuebingen, Germany
Dermatol Surg 28:75-9. 2002..The nevus also contained areas of fetid maceration. After implanting a tissue expander under general anesthesia the nevus was excised. The defect was closed using a rotation flap...
Dermatosurgery using subcutaneous infusion anesthesia with prilocaine and ropivacaine in childrenM Moehrle
Department of Dermatology, University of Tuebingen, Tuebingen, Germany
Pediatr Dermatol 18:469-72. 2001..The additional use of ropivacaine resulted in prolonged postoperative analgesia. SIA in children is a well-accepted, safe anesthesia that in some cases offers an alternative to general anesthesia...
Sentinel lymph node dissection in primary melanoma reduces subsequent regional lymph node metastasis as well as distant metastasis after nodal involvementUlrike Leiter
Department of Dermatology, Eberhard Karls University, Center for Dermato Oncology, Tuebingen, Germany
Ann Surg Oncol 17:129-37. 2010..However, the potential survival benefit of SLND is still controversial...
Confocal laser scanning microscopy vs 3-dimensional histologic imaging in basal cell carcinomaSarah Ziefle
Department of Dermatology, University Hospital, Eberhard Karls University, Liebermeisterstrasse 25, Tubingen, Germany
Arch Dermatol 146:843-7. 2010....
Age and gender are significant independent predictors of survival in primary cutaneous melanomaKonstantinos Lasithiotakis
Division of Dermatologic Oncology, Department of Dermatology, University of Tuebingen, Central Malignant Melanoma Registry of the German Dermatological Society, Tuebingen, Germany
Cancer 112:1795-804. 2008..The aim was to identify age- related and gender-related differences in the clinical presentation and outcome of patients with primary cutaneous melanoma (CM)...
Extramammary Paget's disease: extended subclinical growth detected using three-dimensional histology in routine paraffin procedure and course of the diseaseAlexandra Boehringer
Department of Dermatology, Eberhard Karls University, Tuebingen, Germany
Dermatol Surg 37:1417-26. 2011..Extramammary Paget's disease (EMPD) is a rare tumor of the skin characterized by extended irregular subclinical growth and high recurrence rates after surgery...
Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprineEmmanuella Guenova
Department of Dermatology, Eberhard Karls University, Liebermeister Strasse, 25, Tuebingen, Germany
Melanoma Res 19:271-3. 2009..Our case illustrates the necessity of close dermatological surveillance of allograft recipients, to assure an early recognition of any malignant skin tumor and to reduce the risk of systemic metastatic disease...
Melanoma of the nose: prognostic factors, three-dimensional histology, and surgical strategiesVerena Jahn
Department of Dermatology, University Hospital, Eberhard-Karls-Universitaet, Tuebingen, Germany
Laryngoscope 116:1204-11. 2006..Excision of LMM using 3D histology allowed the reduction of excision margins for better cosmesis and function. Our results do not permit conclusions regarding the prognostic impact of SLNB...
Changes in acral blood flux under local application of ropivacaine and lidocaine with and without an adrenaline additive: a double-blind, randomized, placebo-controlled studyHans Martin Häfner
Department of Dermatology, University of Tubingen, Germany
Clin Hemorheol Microcirc 38:279-88. 2008..Following these results an adrenaline additive can be safely used for anesthetic blocks at the acra in healthy persons...
Acral lentiginous melanoma: conventional histology vs. three-dimensional histologyV Lichte
Department of Dermatology, Universitatsklinikum Tubingen, Eberhard Karls Universitat, Liebermeisterstr 25, D 72076 Tubingen, Germany
Br J Dermatol 160:591-9. 2009..Surgery is mostly based on conventional histological evaluation. With micrographic surgery, continuously spreading tumours can be excised with smaller excision margins for better cosmesis and function...
3D-Histological evaluation of surgery in dermatofibrosarcoma protuberans and malignant fibrous histiocytoma: differences in growth patterns and outcomeH M Häfner
Department of Dermatology, University of Tuebingen, School of Medicine UKT, Liebermeisterstrasse 25, D 72076 Tuebingen, Germany
Eur J Surg Oncol 34:680-6. 2008....
Detection of melanoma cells in sentinel lymph nodes, bone marrow and peripheral blood by a reverse transcription-polymerase chain reaction assay in patients with primary cutaneous melanoma: association with Breslow's tumour thicknessH J Blaheta
Department of Dermatology, Skin Cancer Programme, Eberhard Karls University, Liebermeister Str 25, 72076 Tubingen, Germany
Br J Dermatol 145:195-202. 2001..Tyrosinase reverse transcription-polymerase chain reaction (RT-PCR) has been shown to be highly sensitive in detecting tumour cells in melanoma patients...
Professional risk for skin cancer development in male mountain guides--a cross-sectional studyV Lichte
Department of Dermatology, Eberhard Karls University, Tuebingen, Germany
J Eur Acad Dermatol Venereol 24:797-804. 2010..For reasons of their outdoor work, mountain guides (MG) are heavily exposed to ultraviolet radiation during their work...
Sun protection by red wine?Matthias Moehrle
Department of Dermatology, University Hospital Tuebingen
J Dtsch Dermatol Ges 7:29-32, 29-33. 2009..The UVB-protective potential of wine polyphenols has not been studied so far in humans...
