Jörg Männer

Summary

Country: Germany

Publications

  1. doi request reprint On the form problem of embryonic heart loops, its geometrical solutions, and a new biophysical concept of cardiac looping
    Jörg Männer
    Department of Anatomy and Embryology, Georg August University of Gottingen, Germany
    Ann Anat 195:312-23. 2013
  2. doi request reprint The anatomy of cardiac looping: a step towards the understanding of the morphogenesis of several forms of congenital cardiac malformations
    Jörg Männer
    Department of Anatomy and Cell Biology, Georg August University of Gottingen, Kreuzbergring 36, Gottingen, Germany
    Clin Anat 22:21-35. 2009
  3. doi request reprint High-resolution in vivo imaging of the cross-sectional deformations of contracting embryonic heart loops using optical coherence tomography
    Jörg Männer
    Department of Anatomy and Embryology, Georg August University of Gottingen, Germany
    Dev Dyn 237:953-61. 2008
  4. ncbi request reprint Early morphogenesis of the sinuatrial region of the chick heart: a contribution to the understanding of the pathogenesis of direct pulmonary venous connections to the right atrium and atrial septal defects in hearts with right isomerism of the atrial appe
    Jörg Männer
    Department of Anatomy and Embryology, Georg August University, Gottingen, Germany
    Anat Rec (Hoboken) 290:168-80. 2007
  5. doi request reprint In vivo imaging of the cyclic changes in cross-sectional shape of the ventricular segment of pulsating embryonic chick hearts at stages 14 to 17: a contribution to the understanding of the ontogenesis of cardiac pumping function
    Jörg Männer
    Department of Anatomy and Embryology, Georg August University of Gottingen, Gottingen, Germany
    Dev Dyn 238:3273-84. 2009
  6. ncbi request reprint Extracardiac tissues and the epigenetic control of myocardial development in vertebrate embryos
    Jörg Männer
    Abteilung Anatomie und Embryologie, Georg August Universität zu Göttingen, Kreuzbergring 36, 37075 Gottingen, Germany
    Ann Anat 188:199-212. 2006
  7. ncbi request reprint Ontogenetic development of the helical heart: concepts and facts
    Jörg Männer
    Department of Anatomy Embryology, Georg August University of Gottingen, Kreuzbergring 36, 37075 Gottingen, Germany
    Eur J Cardiothorac Surg 29:S69-74. 2006
  8. ncbi request reprint The morphogenesis of the exstrophy-epispadias complex: a new concept based on observations made in early embryonic cases of cloacal exstrophy
    Jörg Männer
    Abteilung Anatomie Embryologie, Georg August Universität zu Göttingen, Kreuzbergring 36, 37075, Gottingen, Germany
    Anat Embryol (Berl) 210:51-7. 2005
  9. ncbi request reprint Experimental analyses of the function of the proepicardium using a new microsurgical procedure to induce loss-of-proepicardial-function in chick embryos
    Jörg Männer
    Department of Anatomy Embryology, Georg August University of Gottingen, Gottingen, Germany
    Dev Dyn 233:1454-63. 2005
  10. doi request reprint How does the tubular embryonic heart work? Looking for the physical mechanism generating unidirectional blood flow in the valveless embryonic heart tube
    Jörg Männer
    Department of Anatomy and Cell Biology, Georg August University of Gottingen, D 37075 Gottingen, Germany
    Dev Dyn 239:1035-46. 2010

Detail Information

Publications19

  1. doi request reprint On the form problem of embryonic heart loops, its geometrical solutions, and a new biophysical concept of cardiac looping
    Jörg Männer
    Department of Anatomy and Embryology, Georg August University of Gottingen, Germany
    Ann Anat 195:312-23. 2013
    ..Therefore, the present study was conducted to uncover the best geometrical solution of the form problem of embryonic heart loops. This approach may help to identify the biophysics of cardiac looping...
  2. doi request reprint The anatomy of cardiac looping: a step towards the understanding of the morphogenesis of several forms of congenital cardiac malformations
    Jörg Männer
    Department of Anatomy and Cell Biology, Georg August University of Gottingen, Kreuzbergring 36, Gottingen, Germany
    Clin Anat 22:21-35. 2009
    ....
  3. doi request reprint High-resolution in vivo imaging of the cross-sectional deformations of contracting embryonic heart loops using optical coherence tomography
    Jörg Männer
    Department of Anatomy and Embryology, Georg August University of Gottingen, Germany
    Dev Dyn 237:953-61. 2008
    ..The uneven distribution of cardiac jelly seems to prefigure the future AV and cono-truncal endocardial cushions...
  4. ncbi request reprint Early morphogenesis of the sinuatrial region of the chick heart: a contribution to the understanding of the pathogenesis of direct pulmonary venous connections to the right atrium and atrial septal defects in hearts with right isomerism of the atrial appe
    Jörg Männer
    Department of Anatomy and Embryology, Georg August University, Gottingen, Germany
    Anat Rec (Hoboken) 290:168-80. 2007
    ..Our findings shed new light on the pathogenesis of direct pulmonary venous connections to the right atrium and atrial septal defects in hearts with right isomerism of the atrial appendages...
  5. doi request reprint In vivo imaging of the cyclic changes in cross-sectional shape of the ventricular segment of pulsating embryonic chick hearts at stages 14 to 17: a contribution to the understanding of the ontogenesis of cardiac pumping function
    Jörg Männer
    Department of Anatomy and Embryology, Georg August University of Gottingen, Gottingen, Germany
    Dev Dyn 238:3273-84. 2009
    ..The functional significance of our data is discussed with respect to early cardiac pumping function...
  6. ncbi request reprint Extracardiac tissues and the epigenetic control of myocardial development in vertebrate embryos
    Jörg Männer
    Abteilung Anatomie und Embryologie, Georg August Universität zu Göttingen, Kreuzbergring 36, 37075 Gottingen, Germany
    Ann Anat 188:199-212. 2006
    ..These two aspects are, firstly, the development of the so-called heart-forming fields and, secondly, the morphogenesis of the outer compact layer of the myocardial wall...
  7. ncbi request reprint Ontogenetic development of the helical heart: concepts and facts
    Jörg Männer
    Department of Anatomy Embryology, Georg August University of Gottingen, Kreuzbergring 36, 37075 Gottingen, Germany
    Eur J Cardiothorac Surg 29:S69-74. 2006
    ....
  8. ncbi request reprint The morphogenesis of the exstrophy-epispadias complex: a new concept based on observations made in early embryonic cases of cloacal exstrophy
    Jörg Männer
    Abteilung Anatomie Embryologie, Georg August Universität zu Göttingen, Kreuzbergring 36, 37075, Gottingen, Germany
    Anat Embryol (Berl) 210:51-7. 2005
    ..In this paper, we present chick embryos that show cloacal exstrophy at early developmental stages. To the best of our knowledge, this is the first documentation of this rare malformation in young embryos...
  9. ncbi request reprint Experimental analyses of the function of the proepicardium using a new microsurgical procedure to induce loss-of-proepicardial-function in chick embryos
    Jörg Männer
    Department of Anatomy Embryology, Georg August University of Gottingen, Gottingen, Germany
    Dev Dyn 233:1454-63. 2005
    ..We have additionally obtained new data that suggest that the embryonic epicardium may make important contributions to the passive mechanics of the developing heart...
  10. doi request reprint How does the tubular embryonic heart work? Looking for the physical mechanism generating unidirectional blood flow in the valveless embryonic heart tube
    Jörg Männer
    Department of Anatomy and Cell Biology, Georg August University of Gottingen, D 37075 Gottingen, Germany
    Dev Dyn 239:1035-46. 2010
    ..We show that the tubular embryonic heart works neither as a technical peristaltic pump nor as a classic Liebau pump. The question regarding how the embryonic heart tube works still awaits an answer...
  11. ncbi request reprint A chicken model to study the embryology of cloacal exstrophy
    Jörg Männer
    Department of Embryology, Georg August University, Gottingen, Germany
    J Pediatr Surg 38:678-81. 2003
    ..Here, the authors present cases of cloacal exstrophies found in chick embryos subsequent to the application of suramin and trypan blue. This animal model might facilitate insight into the embryology of cloacal exstrophy...
  12. doi request reprint Development of the venous pole of the heart in the frog Xenopus laevis: a morphological study with special focus on the development of the venoatrial connections
    Maike Jahr
    Department of Anatomy and Embryology, Georg August University of Gottingen, Gottingen, Germany
    Dev Dyn 240:1518-27. 2011
    ..This complex arises from the anlage of the interatrial septum and the left half of the sinu-atrial ridge...
  13. ncbi request reprint Morphological and molecular left-right asymmetries in the development of the proepicardium: a comparative analysis on mouse and chick embryos
    Inga Schulte
    Department of Anatomy and Embryology, Georg August University of Gottingen, Germany
    Dev Dyn 236:684-95. 2007
    ..In all three experiments, only the right PE develops the full PE phenotype. Our results suggest that PE development might be controlled by the L-R pathway in the chick but not in the mouse embryo...
  14. doi request reprint Development of the proepicardium in Xenopus laevis
    Maike Jahr
    Department of Anatomy and Embryology, Georg August University of Gottingen, Germany
    Dev Dyn 237:3088-96. 2008
    ..Xenopus might be a good model to uncover the role of left-right signaling pathways in the control of asymmetric PE development...
  15. ncbi request reprint The proepicardium delivers hemangioblasts but not lymphangioblasts to the developing heart
    Jörg Wilting
    Children s Hospital, Pediatrics I, University of Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Dev Biol 305:451-9. 2007
    ..5, indicating a contribution of immigrating lymphangioblasts to the cardiac lymphatic system. Our studies show that coronary blood and lymph vessels are derived from different sources, but grow in close association with each other...
  16. ncbi request reprint A model for left juxtaposition of the atrial appendages in the chick
    Jörg Männer
    Department of Embryology, Center of Anatomy, Georg August University Gottingen, Gottingen, Germany
    Cardiol Young 13:152-60. 2003
    ....
  17. ncbi request reprint On rotation, torsion, lateralization, and handedness of the embryonic heart loop: new insights from a simulation model for the heart loop of chick embryos
    Jörg Männer
    Department of Anatomy and Embryology, Center of Anatomy, Georg August University of Gottingen, Kreuzbergring 36, D 37075 Gottingen, Germany
    Anat Rec A Discov Mol Cell Evol Biol 278:481-92. 2004
    ..The chirality of their helical configuration should be defined, too. The implications of these data with respect to molecular and experimental data are discussed...
  18. pmc Germ layer differentiation during early hindgut and cloaca formation in rabbit and pig embryos
    Romia Hassoun
    Department of Anatomy and Embryology, Gottingen University, Gottingen, Germany
    J Anat 217:665-78. 2010
    ..The results highlight the structural requirements for endoderm formation during development of the hindgut and suggest new mechanisms for the pathogenesis of common urogenital and anorectal malformations...
  19. ncbi request reprint Teratogenic effects of suramin on the chick embryo
    Jörg Männer
    Department of Embryology, Georg August University of Gottingen, Kreuzbergring 36, 37075, Gottingen, Germany
    Anat Embryol (Berl) 206:229-37. 2003
    ..Use of suramin in experimental teratology might help to clarify the morphogenesis of median facial clefts and of some congenital heart defects...