Research Topics
Genomes and Genes | Hans MerzendorferSummaryCountry: Germany Publications
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Publications
A chymotrypsin-like serine protease interacts with the chitin synthase from the midgut of the tobacco hornwormGunnar Broehan
Department of Biology Chemistry, University of Osnabruck, D 49069 Osnabruck, Germany
J Exp Biol 210:3636-43. 2007..Based on our findings we propose that chitin synthesis is controlled by an intestinal proteolytic signalling cascade linking chitin synthase activity to the nutritional state of the larvae...
Microcompartments within the yeast plasma membraneHans Merzendorfer
Department of Biology Chemistry, University of Osnabruck, Animal Physiology, Barbarastr 11, 49076 Osnabruck, Germany
Biol Chem 394:189-202. 2013..Together, they ensure a proper cell division at the end of mitosis, an intricately regulated process, which is essential for the survival and proliferation not only of fungal, but of all eukaryotic cells...
Genomic and proteomic studies on the effects of the insect growth regulator diflubenzuron in the model beetle species Tribolium castaneumHans Merzendorfer
Department of Biology, University of Osnabruck, 49069 Osnabruck, Germany
Insect Biochem Mol Biol 42:264-76. 2012....
The cellular basis of chitin synthesis in fungi and insects: common principles and differencesHans Merzendorfer
University of Osnabruck, Faculty of Biology and Chemistry, Department of Animal Physiology, Barbarastrasse 11, 49076 Osnabruck, Germany
Eur J Cell Biol 90:759-69. 2011..In this review, common principles and differences will be worked out at the levels of gene organization, enzymatic properties, cellular localization and regulation...
Insect chitin synthases: a reviewHans Merzendorfer
Department of Biology Chemistry, Division of Animal Physiology, University of Osnabruck, Germany
J Comp Physiol B 176:1-15. 2006..In the present review, I will summarize recent advances in elucidating the structure, regulation and function of insect chitin synthases as they relate to what is known about fungal chitin synthases and other glycosyltransferases...
Chitin metabolism in insects: structure, function and regulation of chitin synthases and chitinasesHans Merzendorfer
Department of Biology Chemistry, University of Osnabruck, 49069 Osnabruck, Germany
J Exp Biol 206:4393-412. 2003..In this review, we will summarize recent advances in understanding chitin synthesis and its degradation in insects...
Chymotrypsin-like peptidases from Tribolium castaneum: a role in molting revealed by RNA interferenceGunnar Broehan
Department of Biology Chemistry, Division of Animal Physiology, University of Osnabruck, Barbarastr 11, 49069 Osnabruck, Germany
Insect Biochem Mol Biol 40:274-83. 2010..Finally, we performed systemic RNAi experiments. While injections of five TcCTLP-dsRNAs into penultimate larvae did not affect growth or development, injection of dsRNA for TcCTLP-5C and TcCTLP-6C resulted in severe molting defects...
Cloning and expression analysis of midgut chymotrypsin-like proteinases in the tobacco hornwormGunnar Broehan
Department of Biology Chemistry, University of Osnabruck, D 49069 Osnabruck, Germany
J Insect Physiol 54:1243-52. 2008....
A novel role of the yeast CaaX protease Ste24 in chitin synthesisDerek Meissner
Department of Biology Chemistry, University of Osnabruck, 49076 Osnabruck, Germany
Mol Biol Cell 21:2425-33. 2010....
The V-ATPase subunit C binds to polymeric F-actin as well as to monomeric G-actin and induces cross-linking of actin filamentsOlga Vitavska
Department of Biology/Chemistry, Division of Animal Physiology, , , Germany
J Biol Chem 280:1070-6. 2005..Since subunit C has the possibility to dimerize or even to oligomerize, spacing between actin filaments could be variable in size...
The insect plasma membrane H+ V-ATPase: intra-, inter-, and supramolecular aspectsHelmut Wieczorek
Department of Biology Chemistry, University of Osnabruck, 49069 Osnabruck, Germany
J Bioenerg Biomembr 35:359-66. 2003....
A novel role for subunit C in mediating binding of the H+-V-ATPase to the actin cytoskeletonOlga Vitavska
Department of Biology/Chemistry, Division of Animal Physiology, , , Germany
J Biol Chem 278:18499-505. 2003..When the V(1) complex was reconstituted with recombinant subunit C, enhanced binding to F-actin was observed. Thus, subunit C may function as an anchor protein regulating the linkage between V-ATPase and the actin-based cytoskeleton...
The adipokinetic hormone system in Culicinae (Diptera: Culicidae): molecular identification and characterization of two adipokinetic hormone (AKH) precursors from Aedes aegypti and Culex pipiens and two putative AKH receptor variants from A. aegyptiChristian Kaufmann
Department of Biology Chemistry, University of Osnabruck, 49069 Osnabruck, Germany
Insect Biochem Mol Biol 39:770-81. 2009..Based on phylogenetic data, we postulate two closely related types of AKH-receptors that could bind selectively the two AKH peptides found in A. aegypti...
Immunolocalization of chitin synthase in the tobacco hornwormLars Zimoch
Department of Biology, Division of Animal Physiology, , , Germany
Cell Tissue Res 308:287-97. 2002..Apical membranes of salivary glands and tracheal cells were labeled as well, but not those of Malpighian tubules. This is the first time that chitin synthase expression has been visualized in insect tissues on the level of proteins...
Purification of an active, oligomeric chitin synthase complex from the midgut of the tobacco hornwormLars Maue
Department of Biology Chemistry, Division of Animal Physiology, University of Osnabruck, 49069 Osnabruck, Germany
Insect Biochem Mol Biol 39:654-9. 2009..In summary, the chitin synthase from the midgut of Manduca may prove to be a good model for investigating the enzymes' mode of action...
Functional analysis of the ATP-binding cassette (ABC) transporter gene family of Tribolium castaneumGunnar Broehan
Department of Biology Chemistry, Animal Physiology, University of Osnabruck, Osnabrück 49069, Germany
BMC Genomics 14:6. 2013..Most are integral membrane proteins that transport a broad spectrum of substrates across lipid membranes. In insects, ABC transporters are of special interest because of their role in insecticide resistance...
Expression of Manduca sexta V-ATPase genes mvB, mvG and mvd is regulated by ecdysteroidsStephan Reineke
Department of Biology/Chemistry, Division of Animal Physiology, , , Germany
J Exp Biol 205:1059-67. 2002..These findings suggest that putative ecdysone-responsive elements are present in all three promoters. Taken together, our results suggest that the expression of V-ATPase genes is controlled in a coordinated manner by ecdysteroids...
Chitin synthase genes in Manduca sexta: characterization of a gut-specific transcript and differential tissue expression of alternately spliced mRNAs during developmentDavid G Hogenkamp
Department of Biochemistry, Kansas State University, 104 Willard Hall, Manhattan, Kansas 66506, USA
Insect Biochem Mol Biol 35:529-40. 2005....
