Research Topics
| C MeissnerSummaryCountry: Germany Publications
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Detail Information
Publications
Estimation of age at death based on quantitation of the 4977-bp deletion of human mitochondrial DNA in skeletal muscleC Meissner
Department of Legal Medicine, Medical University of Luebeck, Germany
Forensic Sci Int 105:115-24. 1999....
Mutations of mitochondrial DNA - cause or consequence of the ageing process?C Meissner
Department of Forensic Medicine, University Hospital of Schleswig Holstein, Kahlhorststrasse 31 35, 23562, Lubeck, Germany
Z Gerontol Geriatr 40:325-33. 2007..At the moment it is hard to decide, if mitochondrial mutations are the cause or consequence of human ageing, but it is suggested that mitochondrial point mutations are just the consequence, while deletions seem to play a causal role...
A new sensitive short pentaplex (ShoP) PCR for typing of degraded DNAC Meissner
Department of Forensic Medicine, Medical University of Luebeck, Kahlhorststrasse 31 35, 23562 Luebeck, Germany
Forensic Sci Int 166:121-7. 2007..This approach and other similar methods can aid in the analysis of samples where allelic drop out of larger fragments is observed. It is highly recommended to develop more of these multiplexes to improve poor quality DNA typing...
[The mitochondrial genome and aging]C Meissner
Institut für Rechtsmedizin des Universitätsklinikums Lübeck Kahlhorststrasse 31 35 23562 Lübeck, Germany
Z Gerontol Geriatr 34:447-51. 2001..Despite some criticisms of this free radical theory of aging, there is a lot of experimental evidence to support the important role of mitochondria in organismal aging...
Quantification of mitochondrial DNA in human blood cells using an automated detection systemC Meissner
Department of Legal Medicine, Medical University of Luebeck, Kahlhorststrasse 31 35, 23562, Luebeck, Germany
Forensic Sci Int 113:109-12. 2000..Our data did not show any accumulation of the 4977 bp deletion with increasing age as it was observed for several other tissues...
Sudden unexpected infant death due to fibroma of the heartC Meissner
Department of Legal Medicine, Medical University of Luebeck, Germany
J Forensic Sci 45:731-3. 2000..At autopsy, however, the cause of death was determined to be cardiac arrhythmia secondary to fibroma of the heart...
Gunshot injuries to the head and brain caused by low-velocity handguns and rifles. A reviewM Oehmichen
Institute of Legal Medicine, University Hospital Schleswig Holstein, Campus Lubeck, Lubeck, Germany
Forensic Sci Int 146:111-20. 2004....
Brain injury after survived gunshot to the head: reactive alterations at sites remote from the missile trackM Oehmichen
Department of Legal Medicine, Medical University of Lubeck, Kahlhorststrasse 31 35, D 23562, Lubeck, Germany
Forensic Sci Int 115:189-97. 2001....
Detection of the 4977 bp deletion of mitochondrial DNA in different human blood cellsS A Mohamed
Department of Legal Medicine, Medical University of Luebeck, Kahlhorststrasse 31-35, Luebeck 23562, Germany
Exp Gerontol 39:181-8. 2004..Differences of the accumulation pattern may be due to actual individual living behaviour or environmental factors...
Mitotic brain cells are just as prone to mitochondrial deletions as neurons: a large-scale single-cell PCR study of the human caudate nucleusT Storm
Department of Legal Medicine, Medical University of Luebeck, Kahlhorststrasse 31-35, 23562 Luebeck, Germany
Exp Gerontol 37:1389-400. 2002....
Regional potassium distribution in the brain in forensic relevant types of intoxication preliminary morphometric evaluation using a histochemical methodM Oehmichen
Institute of Legal Medicine, Medical University of Lubeck, Germany
Neurotoxicology 22:99-107. 2001..Although the study design allows no statistical analysis, these conclusions are supported by the marked differences in K+ levels in gray and white matter induced by the different toxicants...
Natural deathM Oehmichen
Institute of Legal Medicine, Medical University of Lubeck, Germany
Gerontology 46:105-10. 2000..In the industrialized countries of the West, for example 'natural death' is thought of as the opposite of non-natural types of death such as accidental death, suicide, and homicide...
Histochemical characterization of cytotoxic brain edema. Potassium concentrations after cerebral ischemia and during the postmortem intervalM Oehmichen
Institute of Legal Medicine, Medical University Lubeck, Germany
Exp Toxicol Pathol 52:348-52. 2000..In autoptic human cases, therefore, this technique is of no practical utility in detecting cytotoxic brain edema in postmortem tissue...
Brain injury after gunshot wounding: morphometric analysis of cell destruction caused by temporary cavitationM Oehmichen
Institute of Legal Medicine, Medical University of Lubeck, Germany
J Neurotrauma 17:155-62. 2000..The destruction was probably produced by the temporary cavitation and accords with theoretical considerations and experimental observations...
Fall or shaken: traumatic brain injury in children caused by falls or abuse at home - a review on biomechanics and diagnosisM Oehmichen
Institut fur Rechtsmedizin, Universitatsklinikum Schleswig Holstein, Campus Lubeck, Germany
Neuropediatrics 36:240-5. 2005..The shaken baby syndrome will usually be observed within the first year of life. The doctor has to manifest his diagnosis to the caregivers and - before informing the caregivers - he must be sure of his diagnosis...
Creutzfeldt-Jakob disease (CJD) in a case of suspected chronic heavy metal poisoningM Oehmichen
Department of Legal Medicine, Medical University of Lubeck, Germany
J Forensic Sci 46:702-7. 2001....
Forensic pathological aspects of postmortem imaging of gunshot injury to the head: documentation and biometric dataM Oehmichen
Institute of Legal Medicine, University Hospital Schleswig Holstein, Campus Lubeck, Kahlhorststrasse 31 35, 23562, Lubeck, Germany
Acta Neuropathol 105:570-80. 2003....
Mast cell reactivity at the margin of human skin wounds: an early cell marker of wound survival?M Oehmichen
Department of Legal Medicine, University Hospital of Schleswig Holstein, Kiel Lübeck, Germany
Forensic Sci Int 191:1-5. 2009....
Time of drug elimination in chronic drug abusers. Case study of 52 patients in a "low-step" detoxification wardA Reiter
Department of Legal Medicine, , Kahlhorststrasse 31-35, , Germany
Forensic Sci Int 119:248-53. 2001..3h, total dihydrocodeine (DHC) in urine up to 314.8h, free DHC in urine up to 273.3h, total and free DHC in serum up to 50.1h. Cocaine and its metabolites were largely undetectable in the present study...
Life shortening and physician assistance in dying: euthanasia from the viewpoint of German legal medicineM Oehmichen
Department of Legal Medicine, Medical University of Lubeck, Germany
Gerontology 46:212-8. 2000..Around the world heated debates have broken out on the topic of active euthanasia. Specialists in the field of 'forensic medicine' have taken full part in these discussions...
Mitochondrial DNA deletions and the aging heartSalah A Mohamed
Department of Cardiac Surgery, University of Schleswig Holstein, Campus Luebeck, Ratzeburger Allee 160, 23538 Luebeck, Germany
Exp Gerontol 41:508-17. 2006..Since, apoptosis was induced by the mitochondria-mediated pathway only in transformed cells, the role for apoptosis in normal tissue of the aging heart remains unclear...
Quantification of human mitochondrial DNA in a real time PCRN von Wurmb-Schwark
Institute of Legal Medicine, Christian Albrecht University of Kiel, 24105, Kiel, Germany
Forensic Sci Int 126:34-9. 2002..quot;..
[Mechanisms of ageing from a biogerontological view - new concepts of treatment for elder patients?]C Meissner
Z Gerontol Geriatr 40:311-3. 2007
