Helene Geddert

Summary

Affiliation: Medizinische Klinik
Country: Germany

Publications

  1. doi request reprint [Maxillary ameloblastoma extending into the sinonasal tract]
    H Geddert
    Institut fur Pathologie, St Vincentius Kliniken Karlsruhe, Südendstrasse 37, Karlsruhe, Germany
    Pathologe 34:335-7. 2013
  2. pmc Gene expression profiling for molecular distinction and characterization of laser captured primary lung cancers
    Astrid Rohrbeck
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University Duesseldorf, Duesseldorf, Germany
    J Transl Med 6:69. 2008
  3. doi request reprint EBV-infection in cardiac and non-cardiac gastric adenocarcinomas is associated with promoter methylation of p16, p14 and APC, but not hMLH1
    Helene Geddert
    Institute of Pathology, University Hospital of Dusseldorf, Dusseldorf, Germany
    Anal Cell Pathol (Amst) 33:143-9. 2010
  4. doi request reprint EBV-infection in cardiac and non-cardiac gastric adenocarcinomas is associated with promoter methylation of p16, p14 and APC, but not hMLH1
    Helene Geddert
    Institute of Pathology, University Hospital of Dusseldorf, Germany
    Cell Oncol (Dordr) 34:209-14. 2011
  5. ncbi request reprint Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract
    Helene Geddert
    Institute of Pathology, Heinrich Heine University, Postfach 101007, 40001, Duesseldorf, Germany
    J Cancer Res Clin Oncol 131:803-8. 2005
  6. ncbi request reprint Coexpression of fragile histidine triad and c-kit is relevant for prediction of survival in patients with small cell lung cancer
    Nina Rehfeld
    Klinik für Hämatologie, Onkologie und klinische Immunologie, Heinrich Heine Universitat Dusseldorf, Dusseldorf, Germany
    Cancer Epidemiol Biomarkers Prev 15:2232-8. 2006
  7. ncbi request reprint Correlation of hMLH1 and HPP1 hypermethylation in gastric, but not in esophageal and cardiac adenocarcinoma
    Helene Geddert
    Institute of Pathology, Heinrich Heine University, Dusseldorf, Germany
    Int J Cancer 110:208-11. 2004
  8. ncbi request reprint Hypermethylation of tumor suppressor genes (p16INK4A, p14ARF and APC) in adenocarcinomas of the upper gastrointestinal tract
    Mario Sarbia
    Institute of Pathology, Technical University, Munich, Germany
    Int J Cancer 111:224-8. 2004
  9. ncbi request reprint Methylenetetrahydrofolate reductase C677T polymorphism and risk of adenocarcinoma of the upper gastrointestinal tract
    Mario Sarbia
    Institute of Pathology, Technical University, Munich, Germany
    Scand J Gastroenterol 40:109-11. 2005
  10. ncbi request reprint The role of p63 and deltaNp63 (p40) protein expression and gene amplification in esophageal carcinogenesis
    Helene Geddert
    Institute of Pathology, Department of Surgery, University of Dusseldorf, Germany
    Hum Pathol 34:850-6. 2003

Collaborators

Detail Information

Publications17

  1. doi request reprint [Maxillary ameloblastoma extending into the sinonasal tract]
    H Geddert
    Institut fur Pathologie, St Vincentius Kliniken Karlsruhe, Südendstrasse 37, Karlsruhe, Germany
    Pathologe 34:335-7. 2013
    ..Despite the radical surgical approach a complete resection with wide margins cannot always be achieved. Maxillary ameloblastomas show the highest recurrence rates. ..
  2. pmc Gene expression profiling for molecular distinction and characterization of laser captured primary lung cancers
    Astrid Rohrbeck
    Department of Hematology, Oncology and Clinical Immunology, Heinrich Heine University Duesseldorf, Duesseldorf, Germany
    J Transl Med 6:69. 2008
    ....
  3. doi request reprint EBV-infection in cardiac and non-cardiac gastric adenocarcinomas is associated with promoter methylation of p16, p14 and APC, but not hMLH1
    Helene Geddert
    Institute of Pathology, University Hospital of Dusseldorf, Dusseldorf, Germany
    Anal Cell Pathol (Amst) 33:143-9. 2010
    ..In order to determine underlying distinct aberrant promoter methylation we tested cardiac and non-cardiac GC with regard to the presence of EBV...
  4. doi request reprint EBV-infection in cardiac and non-cardiac gastric adenocarcinomas is associated with promoter methylation of p16, p14 and APC, but not hMLH1
    Helene Geddert
    Institute of Pathology, University Hospital of Dusseldorf, Germany
    Cell Oncol (Dordr) 34:209-14. 2011
    ..In order to determine underlying distinct aberrant promoter methylation we tested cardiac and non-cardiac GC with regard to the presence of EBV...
  5. ncbi request reprint Polymorphism of p16 INK4A and cyclin D1 in adenocarcinomas of the upper gastrointestinal tract
    Helene Geddert
    Institute of Pathology, Heinrich Heine University, Postfach 101007, 40001, Duesseldorf, Germany
    J Cancer Res Clin Oncol 131:803-8. 2005
    ..We investigated the prevalence of single nucleotide polymorphisms in the p16 gene (C540G) and the cyclin D1 gene (G870A), both known to regulate function in G1 arrest and therefore, may play an important role in carcinogenesis...
  6. ncbi request reprint Coexpression of fragile histidine triad and c-kit is relevant for prediction of survival in patients with small cell lung cancer
    Nina Rehfeld
    Klinik für Hämatologie, Onkologie und klinische Immunologie, Heinrich Heine Universitat Dusseldorf, Dusseldorf, Germany
    Cancer Epidemiol Biomarkers Prev 15:2232-8. 2006
    ..In a retrospective analysis of 195 patients with small cell lung cancer (SCLC), we examined the prognostic value of a coexpression of fragile histidine triad (FHIT) protein and c-kit on patient's survival...
  7. ncbi request reprint Correlation of hMLH1 and HPP1 hypermethylation in gastric, but not in esophageal and cardiac adenocarcinoma
    Helene Geddert
    Institute of Pathology, Heinrich Heine University, Dusseldorf, Germany
    Int J Cancer 110:208-11. 2004
    ..Moreover, in gastric cancer, hMLH1 hypermethylation is correlated with hypermethylation of the HPP1 gene...
  8. ncbi request reprint Hypermethylation of tumor suppressor genes (p16INK4A, p14ARF and APC) in adenocarcinomas of the upper gastrointestinal tract
    Mario Sarbia
    Institute of Pathology, Technical University, Munich, Germany
    Int J Cancer 111:224-8. 2004
    ..Our results suggest that hypermethylation of p16(INK4A) and APC are frequent findings in esophageal, cardiac and gastric ADC. Additionally, the data point to a tumor specific methylation pattern in upper gastrointestinal ADC...
  9. ncbi request reprint Methylenetetrahydrofolate reductase C677T polymorphism and risk of adenocarcinoma of the upper gastrointestinal tract
    Mario Sarbia
    Institute of Pathology, Technical University, Munich, Germany
    Scand J Gastroenterol 40:109-11. 2005
  10. ncbi request reprint The role of p63 and deltaNp63 (p40) protein expression and gene amplification in esophageal carcinogenesis
    Helene Geddert
    Institute of Pathology, Department of Surgery, University of Dusseldorf, Germany
    Hum Pathol 34:850-6. 2003
    ..p63 gene amplification is an infrequent finding in esophageal SCCs and ADCs and does not correlate with protein overexpression...
  11. ncbi request reprint Association between NAD(P)H: quinone oxidoreductase 1 (NQ01) inactivating C609T polymorphism and adenocarcinoma of the upper gastrointestinal tract
    Mario Sarbia
    Institute of Pathology, Technical University of Munich, Munchen, Germany
    Int J Cancer 107:381-6. 2003
    ..In conclusion, determination of the NQO1 genotype may gain importance as a stratification marker in future prevention trials for adenocarcinoma of upper gastrointestinal tract...
  12. ncbi request reprint Expression of death-associated protein kinase during tumour progression of human renal cell carcinomas: hypermethylation-independent mechanisms of inactivation
    Nils Wethkamp
    Institute of Pathology, Heinrich Heine University, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    Eur J Cancer 42:264-74. 2006
    ..Despite persistent DAPK transcription and translation, however, the markedly reduced DAPK enzyme activity in our RCC cell lines suggested a post-translational inactivation of DAPK in RCCs...
  13. pmc High EpCAM expression is linked to proliferation and lauren classification in gastric cancer
    Feride Kroepil
    Department of Surgery A, Heinrich Heine University and University Hospital Duesseldorf, Moorenstrasse 5, 40225, Dusseldorf, Germany
    BMC Res Notes 6:253. 2013
    ..Here, we investigated the expression of EpCAM in gastric cancer subtypes and correlated the data to tumor cell proliferation and clinicopathologic factors...
  14. ncbi request reprint Training increases concordance in classifying pulmonary adenocarcinomas according to the novel IASLC/ATS/ERS classification
    Arne Warth
    Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany
    Virchows Arch 461:185-93. 2012
    ..Worldwide harmonization is clearly the next step on the way to a clinically meaningful, internationally accepted use of this novel prognostic and potentially predictive tool in lung pathology...
  15. ncbi request reprint Expression of cyclin B1 in the metaplasia-dysplasia-carcinoma sequence of Barrett esophagus
    Helene Geddert
    Institute of Pathology, University of Dusseldorf, Dusseldorf, Germany
    Cancer 94:212-8. 2002
    ..Cyclin B1 is a key protein for the regulation of G2-M-phase transition during the cell cycle and is essential for initiation of mitosis...
  16. ncbi request reprint C-KIT expression in ductal carcinoma in situ of the breast: co-expression with HER-2/neu
    Raihanatou Diallo
    Institute of Pathology, Heinrich Heine University of Dusseldorf, Germany
    Hum Pathol 37:205-11. 2006
    ..The implications of c-KIT and HER-2 co-expression for breast carcinogenesis should be further evaluated...
  17. ncbi request reprint Prognostic relevance of fragile histidine triad protein expression in patients with small cell lung cancer
    Ulrich Peter Rohr
    Klinik für Hämatologie, Onkologie und klinische Immunologie, Institut fur Pathologie, Heinrich Heine Universitat Dusseldorf, Dusseldorf, Germany
    Clin Cancer Res 11:180-5. 2005
    ..The fragile histidine triad protein (FHIT) is a putative tumor suppressor in patients with lung cancer. In this study, we examined the prognostic value of FHIT expression for survival in patients with small cell lung cancer (SCLC)...