Dieter Wicher

Summary

Affiliation: Max Planck Institute for Chemical Ecology
Country: Germany

Publications

  1. ncbi request reprint Metabolic regulation and behavior: how hunger produces arousal - an insect study
    Dieter Wicher
    Department of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Hans Knoell Str 8, 07745 Jena, Germany
    Endocr Metab Immune Disord Drug Targets 7:304-10. 2007
  2. ncbi request reprint TRPgamma channels are inhibited by cAMP and contribute to pacemaking in neurosecretory insect neurons
    Dieter Wicher
    Department of Neurohormones, Saxon Academy of Sciences, 07743 Jena, Germany
    J Biol Chem 281:3227-36. 2006
  3. ncbi request reprint Differential receptor activation by cockroach adipokinetic hormones produces differential effects on ion currents, neuronal activity, and locomotion
    Dieter Wicher
    Department of Neurohormones, Saxon Academy of Sciences, Jena, Germany
    J Neurophysiol 95:2314-25. 2006
  4. doi request reprint Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels
    Dieter Wicher
    Department of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Hans Knöll St 8, D 07745 Jena, Germany
    Nature 452:1007-11. 2008
  5. doi request reprint dOr83b--receptor or ion channel?
    Dieter Wicher
    Max Planck Institute for Chemical Ecology, Jena, Germany
    Ann N Y Acad Sci 1170:164-7. 2009
  6. doi request reprint Physiological and morphological characterization of local interneurons in the Drosophila antennal lobe
    Yoichi Seki
    Max Planck Institute for Chemical Ecology, Department of Evolutionary Neuroethology, Jena, Germany
    J Neurophysiol 104:1007-19. 2010
  7. ncbi request reprint Peptidergic counter-regulation of Ca(2+)- and Na(+)-dependent K(+) currents modulates the shape of action potentials in neurosecretory insect neurons
    Dieter Wicher
    Saxon Academy of Sciences, Dept Neurohormones, Erbertstr 1, 07743 Jena, Germany
    J Neurophysiol 95:311-22. 2006
  8. pmc Insect odorant response sensitivity is tuned by metabotropically autoregulated olfactory receptors
    Merid N Getahun
    Department Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Jena, Germany
    PLoS ONE 8:e58889. 2013
  9. pmc Temporal response dynamics of Drosophila olfactory sensory neurons depends on receptor type and response polarity
    Merid N Getahun
    Department of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology Jena, Germany
    Front Cell Neurosci 6:54. 2012
  10. doi request reprint A conserved dedicated olfactory circuit for detecting harmful microbes in Drosophila
    Marcus C Stensmyr
    Department of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Hans Knoll Strasse 8, 07745 Jena, Germany
    Cell 151:1345-57. 2012

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Metabolic regulation and behavior: how hunger produces arousal - an insect study
    Dieter Wicher
    Department of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Hans Knoell Str 8, 07745 Jena, Germany
    Endocr Metab Immune Disord Drug Targets 7:304-10. 2007
    ..Systemically injected AKH I stimulates locomotion in contrast to AKH II. This behavioral difference corresponds to the different effectiveness of the AKHs on the level of G-proteins...
  2. ncbi request reprint TRPgamma channels are inhibited by cAMP and contribute to pacemaking in neurosecretory insect neurons
    Dieter Wicher
    Department of Neurohormones, Saxon Academy of Sciences, 07743 Jena, Germany
    J Biol Chem 281:3227-36. 2006
    ..We thus propose that the pTRPgamma protein is involved in forming the channel passing the Ca2+ pakemaking background current in DUM neurons...
  3. ncbi request reprint Differential receptor activation by cockroach adipokinetic hormones produces differential effects on ion currents, neuronal activity, and locomotion
    Dieter Wicher
    Department of Neurohormones, Saxon Academy of Sciences, Jena, Germany
    J Neurophysiol 95:2314-25. 2006
    ..Our findings also show that AKHs act through the same basic mechanisms on neuronal and nonneuronal cells, and they support an integration of metabolic and neuronal effects in homoeostatic mechanisms...
  4. doi request reprint Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels
    Dieter Wicher
    Department of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Hans Knöll St 8, D 07745 Jena, Germany
    Nature 452:1007-11. 2008
    ..Thereby, they provide rapid and transient as well as sensitive and prolonged odorant signalling...
  5. doi request reprint dOr83b--receptor or ion channel?
    Dieter Wicher
    Max Planck Institute for Chemical Ecology, Jena, Germany
    Ann N Y Acad Sci 1170:164-7. 2009
    ..Insect odorant receptors thus form ligand-gated channels as well as complexes of odorant-sensing units and cyclic nucleotide-activated nonselective cation channels...
  6. doi request reprint Physiological and morphological characterization of local interneurons in the Drosophila antennal lobe
    Yoichi Seki
    Max Planck Institute for Chemical Ecology, Department of Evolutionary Neuroethology, Jena, Germany
    J Neurophysiol 104:1007-19. 2010
    ....
  7. ncbi request reprint Peptidergic counter-regulation of Ca(2+)- and Na(+)-dependent K(+) currents modulates the shape of action potentials in neurosecretory insect neurons
    Dieter Wicher
    Saxon Academy of Sciences, Dept Neurohormones, Erbertstr 1, 07743 Jena, Germany
    J Neurophysiol 95:311-22. 2006
    ..The possible physiological relevance of this dual effect is discussed in respect to transmitter release and synaptic integration...
  8. pmc Insect odorant response sensitivity is tuned by metabotropically autoregulated olfactory receptors
    Merid N Getahun
    Department Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Jena, Germany
    PLoS ONE 8:e58889. 2013
    ..Our results indicate that Orco-mediated regulation of OR sensitivity provides tunable ionotropic receptors capable of detecting odors over a wider range of concentrations, providing broadened sensitivity over IRs themselves...
  9. pmc Temporal response dynamics of Drosophila olfactory sensory neurons depends on receptor type and response polarity
    Merid N Getahun
    Department of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology Jena, Germany
    Front Cell Neurosci 6:54. 2012
    ..This diversity increases the capacity of the insect olfactory system to respond to the diverse spatiotemporal signals in the natural environment...
  10. doi request reprint A conserved dedicated olfactory circuit for detecting harmful microbes in Drosophila
    Marcus C Stensmyr
    Department of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Hans Knoll Strasse 8, 07745 Jena, Germany
    Cell 151:1345-57. 2012
    ..The geosmin detection system is a conserved feature in the genus Drosophila that provides flies with a sensitive, specific means of identifying unsuitable feeding and breeding sites...
  11. doi request reprint Piezo controlled microinjection: an in vivo complement for in vitro sensory studies in insects
    Shannon B Olsson
    Department of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Hans Knoell Str 8, Jena 07745, Germany
    J Neurosci Methods 201:385-9. 2011
    ..This approach provides an improved in vivo method to investigate questions in sensory neuron physiology as a complement to heterologous expression systems...
  12. ncbi request reprint Different Ca2+ signalling cascades manifested by mastoparan in the prothoracic glands of the tobacco hornworm, Manduca sexta, and the silkworm, Bombyx mori
    Skarlatos G Dedos
    Saxon Academy of Sciences at Leipzig, Department of Neurohormones, Jena, Germany
    Arch Insect Biochem Physiol 65:52-64. 2007
    ..We propose that in B. mori, mastoparan stimulates Ca(2+) mobilization from ryanodine-sensitive intracellular Ca(2+) stores in prothoracic gland cells...
  13. pmc Antennal transcriptome of Manduca sexta
    Ewald Grosse-Wilde
    Department for Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, 07745 Jena, Germany
    Proc Natl Acad Sci U S A 108:7449-54. 2011
    ..Finally, we compare the expression of the near-complete transcript sets in male and female antennae...
  14. ncbi request reprint A new regulation of non-capacitative calcium entry in insect pacemaker neurosecretory neurons. Involvement of arachidonic acid, no-guanylyl cyclase/cGMP, and cAMP
    Dieter Wicher
    Saxon Academy of Sciences, Department Neurohormones, Erbertstrasse 1, 07743 Jena, Germany
    J Biol Chem 279:50410-9. 2004
    ..We also demonstrate that any mechanism increasing the cGMP level can induce NCCE...
  15. ncbi request reprint Four novel sequences in Drosophila melanogaster homologous to the auxiliary Para sodium channel subunit TipE
    Christian Derst
    Center for Anatomy, Charite Berlin, Philippstr 12, 10115 Berlin, Germany
    Biochem Biophys Res Commun 339:939-48. 2006
    ..We conclude that members of the TEH-family are auxiliary subunits for Para sodium channels and possibly other ion channels...
  16. ncbi request reprint Regulation of capacitative Ca2+ entry by prothoracicotropic hormone in the prothoracic glands of the silkworm, Bombyx mori
    Skarlatos G Dedos
    Saxon Academy of Sciences at Leipzig, Dept Neurohormones, PF 100322, 07703 Jena, Germany
    J Exp Zool A Comp Exp Biol 303:101-12. 2005
    ....
  17. ncbi request reprint BmBKTx1, a novel Ca2+-activated K+ channel blocker purified from the Asian scorpion Buthus martensi Karsch
    Chen Qi Xu
    Key Laboratory of Proteomics, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Graduate School, Shanghai 200031, China
    J Biol Chem 279:34562-9. 2004
    ..As the first reported toxin active on the Drosophila Slo channel dSlo, it will also greatly facilitate studying the physiological role of BK channels in this model organism...