Gregory J Velicer
Affiliation: Max Planck Institute for Biological Cybernetics
- Novel transcriptome patterns accompany evolutionary restoration of defective social development in the bacterium Myxococcus xanthusSupriya V Kadam
Max Planck Institute for Developmental Biology, Germany
Mol Biol Evol 25:1274-81. 2008..These results show that the restoration of a complex trait is accompanied by novel expression patterns across a large number and wide variety of genes, rather than by a large-scale return to ancestral expression patterns...
- Exploitative and hierarchical antagonism in a cooperative bacteriumFrancesca Fiegna
Max-Planck Institute for Developmental Biology, , Germany
PLoS Biol 3:e370. 2005..The finding of several cases of facultative social exploitation among these natural isolates suggests that such exploitation may occur frequently in nature in many prokaryotes with cooperative traits...
- Comprehensive mutation identification in an evolved bacterial cooperator and its cheating ancestorGregory J Velicer
Max Planck Institute for Developmental Biology, 72076 Tubingen, Germany
Proc Natl Acad Sci U S A 103:8107-12. 2006..These results provide insight into the genetic basis of two large adaptive transitions in a social bacterium...
- Social strife in the microbial worldGregory J Velicer
Department of Evolutionary Biology, Max-Planck Institute for Developmental Biology, Spemannstrasse 37, , Germany
Trends Microbiol 11:330-7. 2003
- Evolution of novel cooperative swarming in the bacterium Myxococcus xanthusGregory J Velicer
Department of Evolutionary Biology, Max Planck Institute for Developmental Biology, Spemannstrasse 35, 72076 Tubingen, Germany
Nature 425:75-8. 2003..Though costly to individuals, fibril production greatly enhanced population expansion in groups of interconnected cells. These results show that fundamental transitions to primitive cooperation can readily occur in bacteria...
- Evolution of cooperation: does selfishness restraint lie within?Gregory J Velicer
Max Planck Institut fur Entwicklungsbiologie, Spemannstr 37 39 IV, D 72076 Tubingen, Germany
Curr Biol 15:R173-5. 2005..A recent study at the genetic level suggests that cooperation may also be promoted by the evolution of gene-trait relationships that limit the range of possible cheating mechanisms that can evolve...
- Evolution of an obligate social cheater to a superior cooperatorFrancesca Fiegna
Max Planck Institute for Developmental Biology, Spemannstrasse 35, D 72076 Tubingen, Germany
Nature 441:310-4. 2006..Thus, a temporary state of obligate cheating served as an evolutionary stepping-stone to a novel state of autonomous social dominance...
- Genetic population structure of the soil bacterium Myxococcus xanthus at the centimeter scaleMichiel Vos
Max Planck Institute for Developmental Biology, Spemannstrasse 35, 72076 Tubingen, Germany
Appl Environ Microbiol 72:3615-25. 2006..xanthus evolution is largely clonal. This study shows that M. xanthus is surrounded by a variety of distinct conspecifics in its natural soil habitat at a spatial scale at which encounters among genotypes are likely...
- Experimental social evolution with Myxococcus xanthusGregory J Velicer
Department of Evolutionary Biology, Max-Planck-lnstitute for Developmental Biology, Tuebingen, Germany
Antonie Van Leeuwenhoek 81:155-64. 2002....
- Competitive fates of bacterial social parasites: persistence and self-induced extinction of Myxococcus xanthus cheatersFrancesca Fiegna
Department of Evolutionary Biology, Max-Planck Institute for Developmental Biology, , Germany
Proc Biol Sci 270:1527-34. 2003..Our results empirically demonstrate that social exploitation can destabilize a cooperative biological system and increase the risk of local extinction events...
- Isolation by distance in the spore-forming soil bacterium Myxococcus xanthusMichiel Vos
Max Planck Institute for Developmental Biology, Tubingen 72076, Germany
Curr Biol 18:386-91. 2008..Our results provide new insights into how genetic diversity within species of free-living microbes is distributed from centimeter to global scales...
- Natural variation of gliding motility in a centimetre-scale population of Myxococcus xanthusMichiel Vos
Max Planck Institute for Developmental Biology, Tubingen, Germany
FEMS Microbiol Ecol 64:343-50. 2008..These isolates also varied greatly in swarm morphology and in the effect of nutrient limitation on swarming rate. Our results show that diverse swarming phenotypes can coexist in a small-scale bacterial population...
- Rescue of social motility lost during evolution of Myxococcus xanthus in an asocial environmentGregory J Velicer
Department of Evolutionary Biology, Max Planck Institute for Developmental Biology, Spemannstrasse 37, D 72076 Tubingen, Germany
J Bacteriol 184:2719-27. 2002..Moreover, an amino acid substitution in an evolved genotype was located in a region predicted by genetic complementation analysis to bear an adaptive mutation...
- Strategies of microbial cheater controlMichael Travisano
Department of Biology and Biochemistry, University of Houston, Houston, Texas 77204, USA
Trends Microbiol 12:72-8. 2004..To generate an interpretive framework for future research in microbial behavioural ecology, here we outline a wide range of hypothetical mechanisms by which cheaters might be constrained...
- Resource level affects relative performance of the two motility systems of Myxococcus xanthusKristina L Hillesland
Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824, USA
Microb Ecol 49:558-66. 2005..Several likely benefits of S-motility to the M. xanthus life cycle are discussed, including synergistic interactions with A-motility across a wide variety of conditions...
- Ecological variables affecting predatory success in Myxococcus xanthusKristina L Hillesland
Department of Civil and Environmental Engineering, University of Washington, 167 Wilcox, Box 352700, Seattle, WA 98195, USA
Microb Ecol 53:571-8. 2007..xanthus quickly kills most nearby E. coli or M. luteus regardless of the surface. However, the ability of M. xanthus to search out patches of these prey is affected by surface hardness, the density of prey patches, and the prey species...
- Complete genome sequence of the myxobacterium Sorangium cellulosumSusanne Schneiker
Department of Genetics, Bielefeld University, PO Box 100131, D 33501 Bielefeld, Germany
Nat Biotechnol 25:1281-9. 2007..Seventeen secondary metabolite loci are encoded in the genome, as well as many enzymes with potential utility in industry...
- Discovering the hidden secondary metabolome of Myxococcus xanthus: a study of intraspecific diversityDaniel Krug
Institute for Pharmaceutical Biotechnology, Universitat des Saarlandes, Saarbrucken, Germany
Appl Environ Microbiol 74:3058-68. 2008..These results suggest that M. xanthus may be a promising source of future natural products and that thorough intraspecific screens of other species could reveal many new compounds of interest...
- Identification of the Omega4514 regulatory region, a developmental promoter of Myxococcus xanthus that is transcribed in vitro by the major vegetative RNA polymeraseTong Hao
Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824, USA
J Bacteriol 184:3348-59. 2002..xanthus operon that is transcribed by the major vegetative RNA polymerase, and its regulation appears to involve both negative autoregulation by ORF1 and positive regulation by one or more transcriptional activators...