Peter J Uhlhaas

Summary

Affiliation: Max Planck Institute for Brain Research
Country: Germany

Publications

  1. ncbi request reprint Theory of mind and perceptual context-processing in schizophrenia
    Peter J Uhlhaas
    Max Planck Institute for Brain Research, and Johann Wolfgang Goethe Universität, Frankfurt am Main, Germany
    Cogn Neuropsychiatry 11:416-36. 2006
  2. doi request reprint Visual perceptual organization deficits in Alzheimer's dementia
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Department of Psychiatry, Frankfurt am Main, Germany
    Dement Geriatr Cogn Disord 25:465-75. 2008
  3. pmc The development of neural synchrony reflects late maturation and restructuring of functional networks in humans
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, 60528 Frankfurt am Main, Germany
    Proc Natl Acad Sci U S A 106:9866-71. 2009
  4. ncbi request reprint Evidence for impaired visual context processing in schizotypy with thought disorder
    Peter J Uhlhaas
    Center for Computational and Cognitive Neuroscience and Department of Psychology, University of Stirling, Stirling FK 9 4 LA, UK
    Schizophr Res 68:249-60. 2004
  5. doi request reprint A new look at gamma? High- (>60 Hz) γ-band activity in cortical networks: function, mechanisms and impairment
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstr 46, Frankfurt am Main 60528, Germany
    Prog Biophys Mol Biol 105:14-28. 2011
  6. doi request reprint Neural synchrony and the development of cortical networks
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstr 46, 60528 Frankfurt am Main, Germany
    Trends Cogn Sci 14:72-80. 2010
  7. pmc Perceptual anomalies in schizophrenia: integrating phenomenology and cognitive neuroscience
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstrasse 46, Frankfurt am Main 60528, Germany
    Schizophr Bull 33:142-56. 2007
  8. ncbi request reprint Perceptual grouping in disorganized schizophrenia
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstr 46, Frankfurt am Main, 60528, Germany
    Psychiatry Res 145:105-17. 2006
  9. ncbi request reprint Neural synchrony in brain disorders: relevance for cognitive dysfunctions and pathophysiology
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstrasse 46, Frankfurt am Main, 60528, Germany
    Neuron 52:155-68. 2006
  10. ncbi request reprint Dysfunctional long-range coordination of neural activity during Gestalt perception in schizophrenia
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Frankfurt am Main, 60528, Germany
    J Neurosci 26:8168-75. 2006

Collaborators

Detail Information

Publications33

  1. ncbi request reprint Theory of mind and perceptual context-processing in schizophrenia
    Peter J Uhlhaas
    Max Planck Institute for Brain Research, and Johann Wolfgang Goethe Universität, Frankfurt am Main, Germany
    Cogn Neuropsychiatry 11:416-36. 2006
    ..However, the cognitive mechanisms underlying ToM deficits in schizophrenia are largely unknown. The present study examined the hypothesis that impaired ToM in schizophrenia can be understood as a deficit in context processing...
  2. doi request reprint Visual perceptual organization deficits in Alzheimer's dementia
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Department of Psychiatry, Frankfurt am Main, Germany
    Dement Geriatr Cogn Disord 25:465-75. 2008
    ..In the current study, we examined the hypothesis that perceptual organization is specifically impaired in AD compared to other dementias...
  3. pmc The development of neural synchrony reflects late maturation and restructuring of functional networks in humans
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, 60528 Frankfurt am Main, Germany
    Proc Natl Acad Sci U S A 106:9866-71. 2009
    ..These findings provide evidence for the relationship between neural synchrony and late brain development that has important implications for the understanding of adolescence as a critical period of brain maturation...
  4. ncbi request reprint Evidence for impaired visual context processing in schizotypy with thought disorder
    Peter J Uhlhaas
    Center for Computational and Cognitive Neuroscience and Department of Psychology, University of Stirling, Stirling FK 9 4 LA, UK
    Schizophr Res 68:249-60. 2004
    ..These results support the hypothesis that deficits in visual context processing are the manifestation of a larger disturbance of cognitive coordination in schizotypy and schizophrenia...
  5. doi request reprint A new look at gamma? High- (>60 Hz) γ-band activity in cortical networks: function, mechanisms and impairment
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstr 46, Frankfurt am Main 60528, Germany
    Prog Biophys Mol Biol 105:14-28. 2011
    ..In the final part of the paper, we will review physiological mechanisms underlying the generation of high γ-band oscillations and discuss the functional implications of low vs. high γ-band activity patterns in cortical networks...
  6. doi request reprint Neural synchrony and the development of cortical networks
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstr 46, 60528 Frankfurt am Main, Germany
    Trends Cogn Sci 14:72-80. 2010
    ..These findings highlight the role of neural synchrony for normal brain development as well as its potential importance for understanding neurodevelopmental disorders, such as autism spectrum disorders (ASDs) and schizophrenia...
  7. pmc Perceptual anomalies in schizophrenia: integrating phenomenology and cognitive neuroscience
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstrasse 46, Frankfurt am Main 60528, Germany
    Schizophr Bull 33:142-56. 2007
    ..Relationships of deficits in perceptual organization to cognitive and social dysfunction as well as the possible neurobiological mechanisms are discussed...
  8. ncbi request reprint Perceptual grouping in disorganized schizophrenia
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstr 46, Frankfurt am Main, 60528, Germany
    Psychiatry Res 145:105-17. 2006
    ....
  9. ncbi request reprint Neural synchrony in brain disorders: relevance for cognitive dysfunctions and pathophysiology
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstrasse 46, Frankfurt am Main, 60528, Germany
    Neuron 52:155-68. 2006
    ..Thus, focused search for abnormalities in temporal patterning may be of considerable clinical relevance...
  10. ncbi request reprint Dysfunctional long-range coordination of neural activity during Gestalt perception in schizophrenia
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Frankfurt am Main, 60528, Germany
    J Neurosci 26:8168-75. 2006
    ....
  11. ncbi request reprint The course and clinical correlates of dysfunctions in visual perceptual organization in schizophrenia during the remission of psychotic symptoms
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstr 46, Frankfurt am Main 60528, Germany
    Schizophr Res 75:183-92. 2005
    ....
  12. ncbi request reprint Perceptual organization in schizophrenia spectrum disorders: empirical research and theoretical implications
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Frankfurt am Main, Germany
    Psychol Bull 131:618-32. 2005
    ..These suggest that deficits in perceptual organization may be one manifestation of a wider disturbance in the integration of contextually related information across space and time...
  13. ncbi request reprint Evidence for dysregulated high-frequency oscillations during sensory processing in medication-naïve, first episode schizophrenia
    Limin Sun
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstr, 46, Frankfurt am Main, 60528, Germany Department of Radiology, Massachusetts General Hospital, Harvard University, Cambridge, MA 02129, USA
    Schizophr Res 150:519-25. 2013
    ..However, the presence of aberrant high-frequency oscillations in first-episode (FE), medication-naive patients during sensory processing is unclear...
  14. ncbi request reprint Source-reconstruction of event-related fields reveals hyperfunction and hypofunction of cortical circuits in antipsychotic-naive, first-episode schizophrenia patients during Mooney face processing
    Davide Rivolta
    Department of Neurophysiology, Max Planck Institute for Brain Research and Ernst Strüngmann Institute ESI for Neuroscience in Cooperation with Max Planck Society, Frankfurt am Main 60528, Germany, School of Psychology, University of East London, London E15 4LZ, United Kingdom, Laboratory of Cognitive and Computational Neuroscience, Center for Biomedical Technology, Universidad Politecnica de Madrid, Madrid 28223, Spain, MEG Unit, Brain Imaging Centre, Johann Wolfgang Goethe University, Frankfurt am Main 60529, Germany, Institute for Medical Psychology, Johann Wolfgang Goethe University, Frankfurt am Main 60054, Germany, Department of Psychiatry and Psychotherapy, University of Cologne, Cologne 50924, Germany, Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim 68159, Germany, Department of General Psychiatry, Medical Faculty Heidelberg, Heidelberg University, Heidelberg 69115, Germany, Frankfurt Institute for Advanced Studies, Johann Wolfgang Goethe University, Frankfurt am Main 60438, Germany, and Institute of Neuroscience and Psychology, University of Glasgow, Glasgow G12 8QB, United Kingdom
    J Neurosci 34:5909-17. 2014
    ....
  15. ncbi request reprint Neuroelectromagnetic correlates of perceptual closure processes
    Christine Grützner
    Department of Neurophysiology, Max Planck Institute for Brain Research, Frankfurt am Main, Germany
    J Neurosci 30:8342-52. 2010
    ..Later, at the moment of perceptual closure, inferior temporal cortex areas specialized for the perceived object are activated, i.e., the fusiform gyrus related to face processing for Mooney stimuli...
  16. doi request reprint Impaired gamma-band activity during perceptual organization in adults with autism spectrum disorders: evidence for dysfunctional network activity in frontal-posterior cortices
    Limin Sun
    Department of Neurophysiology, Max Planck Institute for Brain Research, 60528 Frankfurt am Main, Germany
    J Neurosci 32:9563-73. 2012
    ..These findings highlight the contribution of impaired gamma-band activity toward complex visual processing in ASD, suggesting atypical modulation of high-frequency power in frontoposterior networks...
  17. pmc The role of oscillations and synchrony in cortical networks and their putative relevance for the pathophysiology of schizophrenia
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Frankfurt am Main, Germany
    Schizophr Bull 34:927-43. 2008
    ..Perspectives for future research will be discussed in relationship to methodological issues, the utility of neural oscillations as a biomarker, and the neurodevelopmental hypothesis of schizophrenia...
  18. doi request reprint Resting-state functional network correlates of psychotic symptoms in schizophrenia
    Anna Rotarska-Jagiela
    Max Planck Institute for Brain Research, Department of Neurophysiology, Deutschordenstr 46, 60528 Frankfurt a M, Germany
    Schizophr Res 117:21-30. 2010
    ....
  19. ncbi request reprint Gamma-band activity in human prefrontal cortex codes for the number of relevant items maintained in working memory
    Frederic Roux
    MEG Unit, Brain Imaging Center, Johann Wolfgang Goethe University, 60528 Frankfurt am Main, Germany
    J Neurosci 32:12411-20. 2012
    ....
  20. doi request reprint Abnormal neural oscillations and synchrony in schizophrenia
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Frankfurt am Main, 60528, Germany
    Nat Rev Neurosci 11:100-13. 2010
    ..Dysfunctional oscillations may arise owing to anomalies in the brain's rhythm-generating networks of GABA (gamma-aminobutyric acid) interneurons and in cortico-cortical connections...
  21. ncbi request reprint Perceptual organization in ketamine users: preliminary evidence of deficits on night of drug use but not 3 days later
    Peter J Uhlhaas
    Max Planck Institute for Brain Research, Frankfurt, Germany
    J Psychopharmacol 21:347-52. 2007
    ..Levels of dissociation were also higher in ketamine users only on the night of drug use. These preliminary data provide some support for the role of NMDA-receptor hypofunctioning in dysfunctional coordination of cognitive activity...
  22. pmc The phase of thalamic alpha activity modulates cortical gamma-band activity: evidence from resting-state MEG recordings
    Frederic Roux
    Basque Center on Cognition, Brain, and Language BCBL, 2009 Donostia San Sebastian, Spain, MEG Unit, Brain Imaging Center, Goethe University, 60528 Frankfurt am Main, Germany, Max Planck Institute for Brain Research, Department of Neurophysiology, 60438 Frankfurt am Main, Germany, Ernst Strüngmann Institute, 60528 Frankfurt am Main, Germany, Frankfurt Institute for Advanced Sciences, 60438 Frankfurt am Main, Germany, and Institute of Neuroscience and Psychology, Glasgow University, Glasgow, G12 8QB Scotland
    J Neurosci 33:17827-35. 2013
    ....
  23. pmc Deficits in high- (>60 Hz) gamma-band oscillations during visual processing in schizophrenia
    Christine Grützner
    Department of Neurophysiology, Max Planck Institute for Brain Research Frankfurt am Main, Germany
    Front Hum Neurosci 7:88. 2013
    ..Our findings demonstrate that deficits in high gamma-band oscillations as measured by MEG are a sensitive marker for aberrant cortical functioning in schizophrenia, suggesting an important aspect of the pathophysiology of the disorder...
  24. doi request reprint Neuronal dynamics and neuropsychiatric disorders: toward a translational paradigm for dysfunctional large-scale networks
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstr 46, Frankfurt am Main 60528, Germany
    Neuron 75:963-80. 2012
    ..Specifically, we will argue that deficits in temporal coordination lead to a disruption of functional large-scale networks, which in turn can account for several specific dysfunctions associated with these disorders...
  25. ncbi request reprint High-frequency oscillations in schizophrenia
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Frankfurt am Main, Germany
    Clin EEG Neurosci 42:77-82. 2011
    ..Perspectives for future research will be discussed in relationship to methodological issues, the utility of neural oscillations as a biomarker and the neurodevelopmental hypothesis of schizophrenia...
  26. pmc The development of neural synchrony and large-scale cortical networks during adolescence: relevance for the pathophysiology of schizophrenia and neurodevelopmental hypothesis
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Frankfurt am Main, Germany
    Schizophr Bull 37:514-23. 2011
    ....
  27. pmc High-frequency oscillations and the neurobiology of schizophrenia
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschorclenstr 46, Frankfurt am Main, 60528, Germany Ernst Strüngmann Institute ESI for Neuroscience, in Cooperation with Max Planck Society, Deutschorclenstr 46, Frankfurt am Main, 60528, Germany Institute of Neuroscience and Psychology, University of Glasgow, 58 Hillheacl Street, Glasgow G12 8QB, UK
    Dialogues Clin Neurosci 15:301-13. 2013
    ..Finally, we shall identify critical issues for future research in this area. ..
  28. doi request reprint Adolescent brain maturation and cortical folding: evidence for reductions in gyrification
    Daniel Klein
    Department of Neurophysiology, Max Planck Institute for Brain Research, Frankfurt am Main, Germany Ernst Strüngmann Institute ESI for Neuroscience in Cooperation with Max Planck Society, Frankfurt am Main, Germany
    PLoS ONE 9:e84914. 2014
    ..Our data suggest that the observed reductions in GI-values represent an additional, important modification of the cerebral cortex during late brain maturation which may be related to cognitive development. ..
  29. pmc Neural synchrony in cortical networks: history, concept and current status
    Peter J Uhlhaas
    Department of Neurophysiology, Max Planck Institute for Brain Research Frankfurt am Main, Germany
    Front Integr Neurosci 3:17. 2009
    ..We conclude this paper with suggestions for further research as well as with critical issues that need to be addressed in future studies...
  30. doi request reprint Thalamocortical synchronization and cognition: implications for schizophrenia?
    Peter J Uhlhaas
    Institute of Neuroscience and Psychology, University of Glasgow, Hillead St 58, Glasgow, G12 8QB, UK
    Neuron 77:997-9. 2013
    ..2013) investigated synchronization in thalamocortical pathways in an animal model to address the disconnection between brain regions as a mechanism for working memory impairments in the disorder...
  31. ncbi request reprint Perceptual organization in first episode schizophrenia and ultra-high-risk states
    Steven Silverstein
    Center for Cognitive Medicine and Department of Psychiatry, 912 South Wood Street, MC 913, University of Illinois at Chicago, 60612, USA
    Schizophr Res 83:41-52. 2006
    ....
  32. ncbi request reprint What do disturbances in neural synchrony tell us about autism?
    Peter J Uhlhaas
    Biol Psychiatry 62:190-1. 2007
  33. ncbi request reprint Gestalt psychology: the forgotten paradigm in abnormal psychology
    Steven M Silverstein
    Center for Cognitive Medicine, Department of Psychiatry, University of Illinois at Chicago, IL 60612, USA
    Am J Psychol 117:259-77. 2004
    ..Specifically, it appears that a breakdown of Gestalt organizational processes may characterize both the cognitive and the brain processes in schizophrenia...