Anne Spang

Summary

Affiliation: Max Planck Institute for Biological Cybernetics
Country: Germany

Publications

  1. pmc ARF-GAP-mediated interaction between the ER-Golgi v-SNAREs and the COPI coat
    Ulrike Rein
    Friedrich Miescher Laboratory, Max Planck Society, D 72076 Tubingen, Germany
    J Cell Biol 157:395-404. 2002
  2. ncbi request reprint Vesicle transport: a close collaboration of Rabs and effectors
    Anne Spang
    Friedrich Miescher Laboratory of the Max Planck Society, Spemannstrasse 39, D 72076, Tuebingen, Germany
    Curr Biol 14:R33-4. 2004
  3. pmc Arf1p provides an unexpected link between COPI vesicles and mRNA in Saccharomyces cerevisiae
    Mark Trautwein
    Friedrich Miescher Laboratorium, Max Planck Gesellschaft, D 72076 Tubingen, Germany
    Mol Biol Cell 15:5021-37. 2004
  4. doi request reprint Ypt1p is essential for retrograde Golgi-ER transport and for Golgi maintenance in S. cerevisiae
    Faustin Kamena
    Friedrich Miescher Laboratory of the Max Planck Society, Spemannstrasse 39, 72076 Tubingen, Germany
    J Cell Sci 121:1293-302. 2008
  5. ncbi request reprint Tip20p prohibits back-fusion of COPII vesicles with the endoplasmic reticulum
    Faustin Kamena
    Friedrich Miescher Laboratorium der Max Planck Gesellschaft, Spemannstrasse 39, D 72076 Tubingen, Germany
    Science 304:286-9. 2004
  6. ncbi request reprint Knockdown of the centrosomal component SAS-5 results in defects in nuclear morphology in Caenorhabditis elegans
    Cornelia Schmutz
    Friedrich Miescher Laboratorium der Max Planck Gesellschaft, D 72076, Tubingen, Germany
    Eur J Cell Biol 84:75-82. 2005
  7. pmc Involvement of the actin cytoskeleton and homotypic membrane fusion in ER dynamics in Caenorhabditis elegans
    Dmitry Poteryaev
    Friedrich Miescher Laboratorium, Max Planck Gesellschaft, D 72076 Tubingen, Germany
    Mol Biol Cell 16:2139-53. 2005
  8. pmc Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae
    Thomas Sandmann
    Friedrich Miescher Laboratorium der Max Planck Gesellschaft, D 72076 Tubingen, Germany
    Mol Biol Cell 14:3097-113. 2003
  9. pmc Auxin transport inhibitors impair vesicle motility and actin cytoskeleton dynamics in diverse eukaryotes
    Pankaj Dhonukshe
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Universitat Tubingen, Auf der Morgenstelle 3, D 72076 Tubingen, Germany
    Proc Natl Acad Sci U S A 105:4489-94. 2008
  10. pmc The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus
    Auxiliadora Aguilera-Romero
    Department of Cell Biology University of Seville, 41012 Seville, Spain
    J Cell Biol 180:713-20. 2008

Collaborators

Detail Information

Publications15

  1. pmc ARF-GAP-mediated interaction between the ER-Golgi v-SNAREs and the COPI coat
    Ulrike Rein
    Friedrich Miescher Laboratory, Max Planck Society, D 72076 Tubingen, Germany
    J Cell Biol 157:395-404. 2002
    ..The mechanisms by which v-SNAREs interact with COPI and COPII coat proteins seem to be different and may play a key role in determining specificity in vesicle budding...
  2. ncbi request reprint Vesicle transport: a close collaboration of Rabs and effectors
    Anne Spang
    Friedrich Miescher Laboratory of the Max Planck Society, Spemannstrasse 39, D 72076, Tuebingen, Germany
    Curr Biol 14:R33-4. 2004
    ..COPII vesicles transport proteins destined for secretion from the ER to the Golgi apparatus. A recent study has shown that, in budding yeast, the formation of COPII vesicles requires Yip1p, an effector protein of a Rab GTPase...
  3. pmc Arf1p provides an unexpected link between COPI vesicles and mRNA in Saccharomyces cerevisiae
    Mark Trautwein
    Friedrich Miescher Laboratorium, Max Planck Gesellschaft, D 72076 Tubingen, Germany
    Mol Biol Cell 15:5021-37. 2004
    ..Hereby acts the SHE machinery in long-range mRNA transport, whereas COPI vesicles could act as short-range and localization vehicles. The endoplasmic reticulum (ER)-Golgi shuttle might be involved in concentrating mRNA at the ER...
  4. doi request reprint Ypt1p is essential for retrograde Golgi-ER transport and for Golgi maintenance in S. cerevisiae
    Faustin Kamena
    Friedrich Miescher Laboratory of the Max Planck Society, Spemannstrasse 39, 72076 Tubingen, Germany
    J Cell Sci 121:1293-302. 2008
    ..Finally, COPI vesicles generated from Deltaypt1/SLY1-20 Golgi membranes in vitro were depleted of Emp47p and Sec22p. These data demonstrate that Ypt1p plays an essential role in retrograde transport from the Golgi to the ER...
  5. ncbi request reprint Tip20p prohibits back-fusion of COPII vesicles with the endoplasmic reticulum
    Faustin Kamena
    Friedrich Miescher Laboratorium der Max Planck Gesellschaft, Spemannstrasse 39, D 72076 Tubingen, Germany
    Science 304:286-9. 2004
    ..However, a specific mutant of TIP20 did not interfere with COPII vesicle generation but allowed these vesicles to fuse back to the endoplasmic reticulum, a process that does not occur normally in the cell...
  6. ncbi request reprint Knockdown of the centrosomal component SAS-5 results in defects in nuclear morphology in Caenorhabditis elegans
    Cornelia Schmutz
    Friedrich Miescher Laboratorium der Max Planck Gesellschaft, D 72076, Tubingen, Germany
    Eur J Cell Biol 84:75-82. 2005
    ..Yet, this dispersion did neither trigger apoptosis nor affect nuclear envelope assembly. No intrinsic size control for the nucleus seems to exist in the early embryo...
  7. pmc Involvement of the actin cytoskeleton and homotypic membrane fusion in ER dynamics in Caenorhabditis elegans
    Dmitry Poteryaev
    Friedrich Miescher Laboratorium, Max Planck Gesellschaft, D 72076 Tubingen, Germany
    Mol Biol Cell 16:2139-53. 2005
    ..Both proteins have been implicated in homotypic ER membrane fusion. We provide evidence that homotypic membrane fusion is required to form the sheet structure in the early embryo...
  8. pmc Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae
    Thomas Sandmann
    Friedrich Miescher Laboratorium der Max Planck Gesellschaft, D 72076 Tubingen, Germany
    Mol Biol Cell 14:3097-113. 2003
    ..As a consequence, the amount of cargo that can bind COPI might be important for the regulation of the vesicle flow in the early secretory pathway...
  9. pmc Auxin transport inhibitors impair vesicle motility and actin cytoskeleton dynamics in diverse eukaryotes
    Pankaj Dhonukshe
    Zentrum für Molekularbiologie der Pflanzen ZMBP, Universitat Tubingen, Auf der Morgenstelle 3, D 72076 Tubingen, Germany
    Proc Natl Acad Sci U S A 105:4489-94. 2008
    ..These studies also provide an example of how the common eukaryotic process of actin-based vesicle motility can fulfill a plant-specific physiological role...
  10. pmc The yeast p24 complex is required for the formation of COPI retrograde transport vesicles from the Golgi apparatus
    Auxiliadora Aguilera-Romero
    Department of Cell Biology University of Seville, 41012 Seville, Spain
    J Cell Biol 180:713-20. 2008
    ....
  11. pmc Caenorhabditis elegans SAND-1 is essential for RAB-7 function in endosomal traffic
    Dmitry Poteryaev
    Biozentrum, University of Basel, Klingelbergstrasse, Basel, Switzerland
    EMBO J 26:301-12. 2007
    ..We show that SAND-1 is essential for RAB-7 function at the transition from early to late endosomes, but not for RAB-7 function at lysosomes...
  12. pmc Arf1p, Chs5p and the ChAPs are required for export of specialized cargo from the Golgi
    Mark Trautwein
    Friedrich Miescher Laboratorium, Max Planck Gesellschaft, Tubingen, Germany
    EMBO J 25:943-54. 2006
    ..In addition, they are all at least partially localized to the TGN in a Chs5p-dependent manner. Most importantly, several ChAPs can interact physically with Chs3p. We propose that the ChAPs facilitate export of cargo out of the Golgi...
  13. pmc The Gcs1 Arf-GAP mediates Snc1,2 v-SNARE retrieval to the Golgi in yeast
    Micah Robinson
    Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel
    Mol Biol Cell 17:1845-58. 2006
    ..Together, these results suggest that Gcs1 facilitates the incorporation of the Snc v-SNAREs into COPI recycling vesicles and subsequent endosome-Golgi sorting in yeast...
  14. pmc Control of Golgi morphology and function by Sed5 t-SNARE phosphorylation
    Adina Weinberger
    Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel
    Mol Biol Cell 16:4918-30. 2005
    ..Thus, a cycle of Sed5 phosphorylation and dephosphorylation is required for normal t-SNARE function and may choreograph Golgi ordering and dispersal...
  15. pmc The ArfGAP Glo3 is required for the generation of COPI vesicles
    Stephen M Lewis
    Departments of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada B3H 1X5
    Mol Biol Cell 15:4064-72. 2004
    ..Finally, we present evidence supporting a role for ArfGAP protein in the generation of COPI retrograde transport vesicles...