Inge Sillaber

Summary

Affiliation: Max Planck Institute of Psychiatry
Country: Germany

Publications

  1. ncbi request reprint Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors
    Inge Sillaber
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Science 296:931-3. 2002
  2. pmc Gene expression profiling in the stress control brain region hypothalamic paraventricular nucleus reveals a novel gene network including amyloid beta precursor protein
    Amalia Tsolakidou
    Max Planck Institute of Psychiatry, Munich, Germany
    BMC Genomics 11:546. 2010
  3. ncbi request reprint The temporal dynamics of intrahippocampal corticosterone in response to stress-related stimuli with different emotional and physical load: an in vivo microdialysis study in C57BL/6 and DBA/2 inbred mice
    Christoph K Thoeringer
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Psychoneuroendocrinology 32:746-57. 2007
  4. doi request reprint Profiling of behavioral changes and hippocampal gene expression in mice chronically treated with the SSRI paroxetine
    Inge Sillaber
    Max Planck Institute of Psychiatry, 80804 Munich, Germany
    Psychopharmacology (Berl) 200:557-72. 2008
  5. ncbi request reprint Stress and alcohol drinking
    Inge Sillaber
    Max Planck Institute of Psychiatry, Munich, Germany
    Ann Med 36:596-605. 2004
  6. ncbi request reprint Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress
    Marianne B Muller
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, Munich 80804, Germany
    Nat Neurosci 6:1100-7. 2003
  7. ncbi request reprint Identification of molecules potentially involved in mediating the in vivo actions of the corticotropin-releasing hormone receptor 1 antagonist, NBI30775 (R121919)
    Anke Post
    Max Planck Institute of Psychiatry, Kraepelinstrasse 10, 80804 Munich, Germany
    Psychopharmacology (Berl) 180:150-8. 2005
  8. doi request reprint Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1
    Damian Refojo
    Max Planck Institute of Psychiatry, Munich, Germany
    Science 333:1903-7. 2011
  9. doi request reprint Proteomic and metabolomic profiling reveals time-dependent changes in hippocampal metabolism upon paroxetine treatment and biomarker candidates
    Christian Webhofer
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany Graduate School of Systemic Neurosciences, Ludwig Maximilians University Munich, Planegg Martinsried, Germany
    J Psychiatr Res 47:289-98. 2013
  10. ncbi request reprint Location and size of dopaminergic and serotonergic cell populations are controlled by the position of the midbrain-hindbrain organizer
    Claude Brodski
    Max Planck Institute of Psychiatry, 80804 Munich, Germany, and GSF National Research Center for Environment and Health, Technical University Munich, Institute of Developmental Genetics, 85758 Oberschleissheim, Germany
    J Neurosci 23:4199-207. 2003

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors
    Inge Sillaber
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Science 296:931-3. 2002
    ..Alterations in the CRH1 receptor gene and adaptional changes in NR2B subunits may constitute a genetic risk factor for stress-induced alcohol drinking and alcoholism...
  2. pmc Gene expression profiling in the stress control brain region hypothalamic paraventricular nucleus reveals a novel gene network including amyloid beta precursor protein
    Amalia Tsolakidou
    Max Planck Institute of Psychiatry, Munich, Germany
    BMC Genomics 11:546. 2010
    ..Gene expression and regulation was determined by microarray analyses and further evaluated by bioinformatics tools including pathway and cluster analyses...
  3. ncbi request reprint The temporal dynamics of intrahippocampal corticosterone in response to stress-related stimuli with different emotional and physical load: an in vivo microdialysis study in C57BL/6 and DBA/2 inbred mice
    Christoph K Thoeringer
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Psychoneuroendocrinology 32:746-57. 2007
    ..In addition, our study highlights the use of in vivo microdialysis to assess the neuroendocrine endophenotype of animal models via profiling of stimulus-response patterns of stress hormones...
  4. doi request reprint Profiling of behavioral changes and hippocampal gene expression in mice chronically treated with the SSRI paroxetine
    Inge Sillaber
    Max Planck Institute of Psychiatry, 80804 Munich, Germany
    Psychopharmacology (Berl) 200:557-72. 2008
    ..Monoamine-based antidepressants inhibit neurotransmitter reuptake within short time. However, it commonly takes several weeks until clinical symptoms start to resolve--indicating the involvement of effects distant from reuptake inhibition...
  5. ncbi request reprint Stress and alcohol drinking
    Inge Sillaber
    Max Planck Institute of Psychiatry, Munich, Germany
    Ann Med 36:596-605. 2004
    ..Individuals with a dysfunctional HPA axis, inherited and/or acquired, might represent such a subgroup of stress-motivated drinkers...
  6. ncbi request reprint Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress
    Marianne B Muller
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, Munich 80804, Germany
    Nat Neurosci 6:1100-7. 2003
    ..Furthermore, we provide evidence for a new role of limbic Crhr1 in neuroendocrine adaptation to stress...
  7. ncbi request reprint Identification of molecules potentially involved in mediating the in vivo actions of the corticotropin-releasing hormone receptor 1 antagonist, NBI30775 (R121919)
    Anke Post
    Max Planck Institute of Psychiatry, Kraepelinstrasse 10, 80804 Munich, Germany
    Psychopharmacology (Berl) 180:150-8. 2005
    ..Despite its therapeutic efficacy, there is only little information about its mechanisms of action on cellular and molecular targets...
  8. doi request reprint Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1
    Damian Refojo
    Max Planck Institute of Psychiatry, Munich, Germany
    Science 333:1903-7. 2011
    ..These results define a bidirectional model for the role of CRHR1 in anxiety and suggest that an imbalance between CRHR1-controlled anxiogenic glutamatergic and anxiolytic dopaminergic systems might lead to emotional disorders...
  9. doi request reprint Proteomic and metabolomic profiling reveals time-dependent changes in hippocampal metabolism upon paroxetine treatment and biomarker candidates
    Christian Webhofer
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany Graduate School of Systemic Neurosciences, Ludwig Maximilians University Munich, Planegg Martinsried, Germany
    J Psychiatr Res 47:289-98. 2013
    ....
  10. ncbi request reprint Location and size of dopaminergic and serotonergic cell populations are controlled by the position of the midbrain-hindbrain organizer
    Claude Brodski
    Max Planck Institute of Psychiatry, 80804 Munich, Germany, and GSF National Research Center for Environment and Health, Technical University Munich, Institute of Developmental Genetics, 85758 Oberschleissheim, Germany
    J Neurosci 23:4199-207. 2003
    ..In addition, our data suggest that the position of the MHO during embryogenesis can modulate adult locomotor activity...
  11. ncbi request reprint Importance of NO/cGMP signalling via cGMP-dependent protein kinase II for controlling emotionality and neurobehavioural effects of alcohol
    Claudia Werner
    Institut fur Pharmakologie und Toxikologie, Technische Universitat Munchen, Biedersteiner Strasse 29, 80802 Munchen, Germany
    Eur J Neurosci 20:3498-506. 2004
    ..No taste differences to sweet solutions were observed compared to control animals. In summary, our data show that cGKII activity modulates anxiety-like behaviour and neurobehavioural effects of alcohol...
  12. ncbi request reprint The neuronal nitric oxide synthase gene is critically involved in neurobehavioral effects of alcohol
    Rainer Spanagel
    Department of Psychopharmacology, Central Institute of Mental Health, University of Heidelberg, 68159 Mannheim, Germany
    J Neurosci 22:8676-83. 2002
    ..In summary, the nNOS gene is critically involved in the regulation of neurobehavioral effects of alcohol...
  13. pmc Corticotropin-releasing hormone activates ERK1/2 MAPK in specific brain areas
    Damian Refojo
    Departamento Fisiología y Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Laboratorio de Fisiologia y Biologia Molecular, Universidad de Buenos Aires, 1428 Buenos Aires, Argentina
    Proc Natl Acad Sci U S A 102:6183-8. 2005
    ..These findings underscore the fact that CRH activates p-ERK1/2 through CRHR1 only in selected brain regions, pointing to a specific role of this pathway in mediating behavioral adaptation to stress...
  14. ncbi request reprint The glucocorticoid receptor as a potential target to reduce cocaine abuse
    Véronique Deroche-Gamonet
    Institut National de la Sante et de la Recherche Medicale, Unité 588, Bordeaux 33077, France
    J Neurosci 23:4785-90. 2003
    ..This suggests that targeting GR function in the brain could provide new therapeutic strategies to treat cocaine addiction for which there is no available treatment...