Research Topics
Genomes and Genes | Anna ShevchenkoSummaryAffiliation: Max Planck Institute of Molecular Cell Biology and Genetics Country: Germany Publications
| Collaborators
|
Detail Information
Publications
Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environmentAnna Shevchenko
MPI of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
Genome Biol 9:R167. 2008..Because uncertainties remain regarding the accuracy of proteomic data, several issues need to be resolved before comparative proteomics can be fruitful...
Identification of glycosylated marker proteins of epithelial polarity in MDCK cells by homology driven proteomicsJoachim Fullekrug
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
BMC Biochem 7:8. 2006..Monoclonal antibodies against apical gp114 and basolateral p58 have served as important tools in these studies. However, the molecular identity of these membrane glycoproteins has not been known...
A comparative analysis of an orthologous proteomic environment in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombeAssen Roguev
Genomics, Technische Universitat Dresden, c o Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
Mol Cell Proteomics 3:125-32. 2004..We speculate that conservation of the core components of protein assemblies and variability of hyperlinks represents a general principle in the molecular organization of eukaryotic proteomes...
The histone 3 lysine 36 methyltransferase, SET2, is involved in transcriptional elongationDaniel Schaft
BIOTEC, Technische Universitaet Dresden, MPI CBG, Pfotenhauerstrasse 108, D 01307, Germany
Nucleic Acids Res 31:2475-82. 2003..Since SET2 is also a histone methyltransferase, these results suggest a role for histone 3 lysine 36 methylation in transcriptional elongation...
High conservation of the Set1/Rad6 axis of histone 3 lysine 4 methylation in budding and fission yeastsAssen Roguev
BIOTEC, Technische Universitaet Dresden, c o Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, Germany
J Biol Chem 278:8487-93. 2003..Thus, we infer that Set1C is highly conserved in eukaryotes but observe that its links to the proteome are not...
Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's diseaseArun Pal
Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany
J Cell Biol 172:605-18. 2006..In revealing an unexpected link between Rab5, HAP40, and Htt, we uncovered a new mechanism regulating cytoskeleton-dependent endosome dynamics and its dysfunction under pathological conditions...
Deciphering protein complexes and protein interaction networks by tandem affinity purification and mass spectrometry: analytical perspectiveAnna Shevchenko
Max Planck Institute of Molecular Cell Biology and Genetics MPI CBG, Pfotenhauerstrasse 108, 01307 Dresden, Germany
Mol Cell Proteomics 1:204-12. 2002..Concordance with the results of genome-wide two-hybrid screening was poor (14% of identified interactors overlapped) suggesting that the two approaches may provide complementary views on physical interactions within the proteome...
APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartmentMarta Miaczynska
Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
Cell 116:445-56. 2004..Our findings identify an endosomal compartment bearing Rab5 and APPL proteins as an intermediate in signaling between the plasma membrane and the nucleus...
Crumbs regulates rhodopsin transport by interacting with and stabilizing myosin VShirin Meher Pocha
Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany
J Cell Biol 195:827-38. 2011..Our data provide, for the first time, a molecular mechanism for the light-dependent degeneration of PRCs observed in crb mutant retinas...
Horizontal carryover of proteins on one-dimensional polyacrylamide gels may jeopardize gel-enhanced liquid chromatography mass spectrometry proteomic interpretationsAndrea Knaust
MPI of Molecular Cell Biology and Genetics, 01307 Dresden, Germany
Anal Biochem 421:779-81. 2012..Therefore, we suggest that experimental and control samples should always be loaded on separate gels...
Sequence similarity-based proteomics in insects: characterization of the larvae venom of the Brazilian moth Cerodirphia speciosaAnna Shevchenko
Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
J Proteome Res 4:862-9. 2005..The protein composition of the venom suggested that envenoming by C. speciosa toxins might proceed through the contact with its hemolymph, similarly to another toxic Lepidoptera organism, Lonomia obliqua...
PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alphaIris Eke
OncoRay Center for Radiation Research in Oncology, Medical Faculty Carl Gustav Carus, Dresden University of Technology, 01307 Dresden, Germany
J Clin Invest 120:2516-27. 2010....
