S Schweiger

Summary

Affiliation: Max Planck Institute for Molecular Genetics
Country: Germany

Publications

  1. pmc The Opitz syndrome gene product, MID1, associates with microtubules
    S Schweiger
    Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany
    Proc Natl Acad Sci U S A 96:2794-9. 1999
  2. ncbi request reprint AIRE encodes a nuclear protein co-localizing with cytoskeletal filaments: altered sub-cellular distribution of mutants lacking the PHD zinc fingers
    C Rinderle
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, D 14195 Berlin, Germany
    Hum Mol Genet 8:277-90. 1999
  3. ncbi request reprint Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22
    N A Quaderi
    Telethon Institute of Genetics and Medicine TIGEM, Milan, Italy
    Nat Genet 17:285-91. 1997
  4. ncbi request reprint MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation
    A Trockenbacher
    Institute of Biochemistry, Peter Mayr Strasse 1a, 6020 Innsbruck, Austria
    Nat Genet 29:287-94. 2001
  5. ncbi request reprint DXS6673E encodes a predominantly nuclear protein, and its mouse ortholog DXHXS6673E is alternatively spliced in a developmental- and tissue-specific manner
    M P Scheer
    Max Planck Institut fur Molekulare Genetik, Ihnestrasse 73, Berlin Dahlem, D 14195, Germany
    Genomics 63:123-32. 2000

Collaborators

  • A Trockenbacher
  • M P Scheer
  • C Rinderle
  • H H Ropers
  • N A Quaderi
  • J Winter
  • J Foerster
  • S Krauss
  • V Suckow
  • R Schneider
  • H Ropers
  • H G Nothwang
  • A Schulz
  • J Wirth
  • S van der Maarel
  • S K├╝bart
  • H Lehrach
  • M L Yaspo
  • H M Christensen
  • G Andolfi
  • M Volta
  • K Gaudenz
  • J M Opitz
  • R C Hennekam
  • A Ballabio
  • S Gilgenkrantz
  • E I Rugarli
  • W Berger
  • G J Feldman
  • B Franco
  • R W Marion
  • M Muenke

Detail Information

Publications5

  1. pmc The Opitz syndrome gene product, MID1, associates with microtubules
    S Schweiger
    Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany
    Proc Natl Acad Sci U S A 96:2794-9. 1999
    ..These data give an idea of the possible molecular pathomechanism underlying the OS phenotype...
  2. ncbi request reprint AIRE encodes a nuclear protein co-localizing with cytoskeletal filaments: altered sub-cellular distribution of mutants lacking the PHD zinc fingers
    C Rinderle
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, D 14195 Berlin, Germany
    Hum Mol Genet 8:277-90. 1999
    ..N-terminal AIRE fragments deleted for the PHD domain show altered nuclear localization, suggesting that the APECED mutations may elicit their primary effects in the nucleus...
  3. ncbi request reprint Opitz G/BBB syndrome, a defect of midline development, is due to mutations in a new RING finger gene on Xp22
    N A Quaderi
    Telethon Institute of Genetics and Medicine TIGEM, Milan, Italy
    Nat Genet 17:285-91. 1997
    ..The association of MID1 with OS suggests an important role for this gene in midline development...
  4. ncbi request reprint MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation
    A Trockenbacher
    Institute of Biochemistry, Peter Mayr Strasse 1a, 6020 Innsbruck, Austria
    Nat Genet 29:287-94. 2001
    ..Elevated PP2Ac causes hypophosphorylation of MAPs, a pathological mechanism that is consistent with the OS phenotype...
  5. ncbi request reprint DXS6673E encodes a predominantly nuclear protein, and its mouse ortholog DXHXS6673E is alternatively spliced in a developmental- and tissue-specific manner
    M P Scheer
    Max Planck Institut fur Molekulare Genetik, Ihnestrasse 73, Berlin Dahlem, D 14195, Germany
    Genomics 63:123-32. 2000
    ..Three distinct protein distribution patterns in COS-7 cells could be identified...