Research Topics
Genomes and GenesSpecies | Korbinian SchneebergerSummaryAffiliation: Max Planck Institute for Biological Cybernetics Country: Germany Publications
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Detail Information
Publications
Simultaneous alignment of short reads against multiple genomesKorbinian Schneeberger
Department of Molecular Biology, Max Planck Institute for Developmental Biology, Spemannstrasse 37 39, D 72076 Tubingen, Germany
Genome Biol 10:R98. 2009..Demonstrated benefits include access to polymorphisms that cannot be identified by alignments against the reference alone. Download GenomeMapper at http://1001genomes.org...
Natural variation in biogenesis efficiency of individual Arabidopsis thaliana microRNAsMarco Todesco
Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tubingen, Germany
Curr Biol 22:166-70. 2012..Our results suggest that natural variation in miRNA biogenesis resulting from cis mutations is a common contributor to phenotypic variation in plants...
The rate and molecular spectrum of spontaneous mutations in Arabidopsis thalianaStephan Ossowski
Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tubingen, Germany
Science 327:92-4. 2010..We explain this very biased spectrum of base substitution mutations as a result of two main processes: deamination of methylated cytosines and ultraviolet light-induced mutagenesis...
Whole-genome sequencing of multiple Arabidopsis thaliana populationsJun Cao
Max Planck Institute for Developmental Biology, Tubingen, Germany
Nat Genet 43:956-63. 2011..thaliana diverged from its closest relative 10 million years ago with the spectrum observed in the laboratory. Recent species-wide selective sweeps are rare, and potentially deleterious mutations are more common in marginal populations...
Sequencing of natural strains of Arabidopsis thaliana with short readsStephan Ossowski
Department of Molecular Biology, Max Planck Institute for Developmental Biology, Tubingen, Germany
Genome Res 18:2024-33. 2008..Our pipeline for aligning reads and predicting SNPs and indels, SHORE, is available for download at http://1001genomes.org...
Genome-wide comparison of nucleotide-binding site-leucine-rich repeat-encoding genes in ArabidopsisYa Long Guo
Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tuebingen, Germany
Plant Physiol 157:757-69. 2011..Finally, in contrast to Drosophila, there is a clearly positive relationship between interspecific divergence and intraspecific polymorphisms...
Reference-guided assembly of four diverse Arabidopsis thaliana genomesKorbinian Schneeberger
Department of Molecular Biology, Max Planck Institute for Developmental Biology, D 72076 Tubingen, Germany
Proc Natl Acad Sci U S A 108:10249-54. 2011..Genome assemblies, raw reads, and further information are accessible through http://1001genomes.org/projects/assemblies.html...
Synteny-based mapping-by-sequencing enabled by targeted enrichmentVinicius C Galvão
Max Planck Institute for Developmental Biology, 72076 Tubingen, Germany
Plant J 71:517-26. 2012....
Structure determinants for accurate processing of miR172a in Arabidopsis thalianaSchallum Werner
Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tubingen, Germany
Curr Biol 20:42-8. 2010..Our ability to engineer de novo a functional minimal miRNA precursor highlights that we have discovered several elements both necessary and sufficient for accurate miRNA processing...
Fast-forward genetics enabled by new sequencing technologiesKorbinian Schneeberger
Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tubingen, Germany
Trends Plant Sci 16:282-8. 2011..Deployment of such genes to improve crops or engineer microbes that produce valuable compounds heralds a potential paradigm shift for plant biology...
A genetic defect caused by a triplet repeat expansion in Arabidopsis thalianaSridevi Sureshkumar
Department of Molecular Biology, Max Planck Institute for Developmental Biology, D 72076 Tubingen, Germany
Science 323:1060-3. 2009..The Bur-0 IIL1 defect thus presents a genetically tractable model for triplet repeat expansions and their variability in natural populations...
Evolution of Arabidopsis thaliana microRNAs from random sequencesFelipe Fenselau de Felippes
Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tubingen, Germany
RNA 14:2455-9. 2008..Subsequent stabilization through coevolution with initially fortuitous targets may lead to fixation of a small subset of these proto-miRNA genes...
