Constance Scharff

Summary

Affiliation: Max Planck Institute for Molecular Genetics
Country: Germany

Publications

  1. ncbi FoxP2 expression in avian vocal learners and non-learners
    Sebastian Haesler
    Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany
    J Neurosci 24:3164-75. 2004
  2. ncbi Genetic components of vocal learning
    Constance Scharff
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
    Ann N Y Acad Sci 1016:325-47. 2004
  3. ncbi An evolutionary perspective on FoxP2: strictly for the birds?
    Constance Scharff
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany Freie Universität Berlin, Department of Animal Behavior, Grunewaldstrasse 34, 12165 Berlin, Germany
    Curr Opin Neurobiol 15:694-703. 2005
  4. ncbi Recruitment of FoxP2-expressing neurons to area X varies during song development
    Christelle Rochefort
    Laboratory of Animal Behavior, Freie Universitat Berlin, Takustr 6, 14195 Berlin, Germany
    Dev Neurobiol 67:809-17. 2007
  5. ncbi Incomplete and inaccurate vocal imitation after knockdown of FoxP2 in songbird basal ganglia nucleus Area X
    Sebastian Haesler
    Max Planck Institute for Molecular Genetics, Berlin, Germany
    PLoS Biol 5:e321. 2007
  6. ncbi Mutations in the polyglutamine binding protein 1 gene cause X-linked mental retardation
    Vera M Kalscheuer
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, D 14195 Berlin, Germany
    Nat Genet 35:313-5. 2003
  7. ncbi Gene expression changes in the course of neural progenitor cell differentiation
    Ulf Gurok
    Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany
    J Neurosci 24:5982-6002. 2004
  8. ncbi HVC interneurons are not renewed in adult male zebra finches
    Sophie Scotto Lomassese
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, Berlin, Germany
    Eur J Neurosci 25:1663-8. 2007
  9. ncbi Evo-devo, deep homology and FoxP2: implications for the evolution of speech and language
    Constance Scharff
    Department of Animal Behavior, Freie Universitat Berlin, Takustr 6, 14195 Berlin, Germany
    Philos Trans R Soc Lond B Biol Sci 366:2124-40. 2011
  10. ncbi Singing mice, songbirds, and more: models for FOXP2 function and dysfunction in human speech and language
    Stephanie A White
    Department of Physiological Science, University of California, Los Angeles, California 90095, USA
    J Neurosci 26:10376-9. 2006

Collaborators

Detail Information

Publications11

  1. ncbi FoxP2 expression in avian vocal learners and non-learners
    Sebastian Haesler
    Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany
    J Neurosci 24:3164-75. 2004
    ..We conclude that differential expression of FoxP2 in avian vocal learners might be associated with vocal plasticity...
  2. ncbi Genetic components of vocal learning
    Constance Scharff
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
    Ann N Y Acad Sci 1016:325-47. 2004
    ..These latter regions also express FoxP2 in mammals and reptiles. We conclude that FoxP2 is important for the building and function of brain pathways including, but not limited to, those essential for learned vocal communication...
  3. ncbi An evolutionary perspective on FoxP2: strictly for the birds?
    Constance Scharff
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany Freie Universität Berlin, Department of Animal Behavior, Grunewaldstrasse 34, 12165 Berlin, Germany
    Curr Opin Neurobiol 15:694-703. 2005
    ..This suggests that FoxP2 plays important roles both in the development of neural circuits and in the postnatal behaviors they mediate...
  4. ncbi Recruitment of FoxP2-expressing neurons to area X varies during song development
    Christelle Rochefort
    Laboratory of Animal Behavior, Freie Universitat Berlin, Takustr 6, 14195 Berlin, Germany
    Dev Neurobiol 67:809-17. 2007
    ..Together these results raise the possibility that neuronal recruitment and FoxP2 expression in Area X are associated with vocal learning...
  5. ncbi Incomplete and inaccurate vocal imitation after knockdown of FoxP2 in songbird basal ganglia nucleus Area X
    Sebastian Haesler
    Max Planck Institute for Molecular Genetics, Berlin, Germany
    PLoS Biol 5:e321. 2007
    ..Our findings provide the first example of a functional gene analysis in songbirds and suggest that normal auditory-guided vocal motor learning requires FoxP2...
  6. ncbi Mutations in the polyglutamine binding protein 1 gene cause X-linked mental retardation
    Vera M Kalscheuer
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, D 14195 Berlin, Germany
    Nat Genet 35:313-5. 2003
    ..PQBP1 has previously been implicated in the pathogenesis of polyglutamine expansion diseases. Our findings link this gene to XLMR and shed more light on the pathogenesis of this common disorder...
  7. ncbi Gene expression changes in the course of neural progenitor cell differentiation
    Ulf Gurok
    Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany
    J Neurosci 24:5982-6002. 2004
    ..Our results provide new insights into the genetic program of neural progenitor differentiation and give strong hints to as yet unknown cellular communications within the adult subventricular zone stem cell niche...
  8. ncbi HVC interneurons are not renewed in adult male zebra finches
    Sophie Scotto Lomassese
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, Berlin, Germany
    Eur J Neurosci 25:1663-8. 2007
    ..This implies that the sum of HVC(IN) expressing the different calcium-binding proteins constitute all inhibitory HVC(IN). Together these results strongly suggest that only HVC(RA) are recruited into the adult HVC...
  9. ncbi Evo-devo, deep homology and FoxP2: implications for the evolution of speech and language
    Constance Scharff
    Department of Animal Behavior, Freie Universitat Berlin, Takustr 6, 14195 Berlin, Germany
    Philos Trans R Soc Lond B Biol Sci 366:2124-40. 2011
    ..The emerging picture can help us understand how complex cognitive traits can 'descend with modification'...
  10. ncbi Singing mice, songbirds, and more: models for FOXP2 function and dysfunction in human speech and language
    Stephanie A White
    Department of Physiological Science, University of California, Los Angeles, California 90095, USA
    J Neurosci 26:10376-9. 2006
    ..Below, we describe genetic through behavioral techniques used currently to investigate FoxP2 in birds, rodents, and humans for discovery of the neural bases of vocal learning and language...
  11. ncbi A molecular neuroethological approach for identifying and characterizing a cascade of behaviorally regulated genes
    Kazuhiro Wada
    Department of Neurobiology and Duke Bioinformatics Shared Resource, Duke University Medical Center, Durham, NC 27710, USA
    Proc Natl Acad Sci U S A 103:15212-7. 2006
    ..This publicly accessible resource http://songbirdtranscriptome.net can now be used to study molecular neuroethological mechanisms of behavior...