Research Topics
Species | Tim C RoloffSummaryAffiliation: Max Planck Institute for Molecular Genetics Country: Germany Publications
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Detail Information
Publications
Comparative study of methyl-CpG-binding domain proteinsTim C Roloff
Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
BMC Genomics 4:1. 2003..So far, five vertebrate MBD proteins have been described as MBD family members: MBD1, MBD2, MBD3, MBD4 and MECP2...
Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndromeUlrike A Nuber
Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
Hum Mol Genet 14:2247-56. 2005..Given the known deleterious effect of glucocorticoid exposure on brain development, our data raise the possibility that disruption of MeCP2-dependent regulation of stress-responsive genes contributes to the symptoms of RTT...
Chromatin, epigenetics and stem cellsTim C Roloff
Max Planck Institute for Molecular Genetics, Ihnestrasse 73, D-14195 Berlin, Germany
Eur J Cell Biol 84:123-35. 2005..Moreover, a modification of the current epigenetics definition is proposed that is not restricted by the heritability of gene expression throughout cell divisions and excludes translational gene expression control...
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitorsFabio Mohn
Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland
Mol Cell 30:755-66. 2008..These data suggest a model how de novo DNA methylation and dynamic switches in Polycomb targets restrict pluripotency and define the developmental potential of progenitor cells...
