Jorn Piel

Summary

Affiliation: Max Planck Institute for Chemical Ecology
Country: Germany

Publications

  1. ncbi request reprint Metabolites from symbiotic bacteria
    Jorn Piel
    Max Planck Institute for Chemical Ecology, Department of Bioorganic Chemistry, Hans Knoll Strasse 8, Beutenberg Campus, 07745 Jena, Germany
    Nat Prod Rep 21:519-38. 2004
  2. pmc A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles
    Jorn Piel
    Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, Winzerlaer Strasse 10, Beutenberg Campus, 07745 Jena, Germany
    Proc Natl Acad Sci U S A 99:14002-7. 2002
  3. ncbi request reprint Unprecedented diversity of catalytic domains in the first four modules of the putative pederin polyketide synthase
    Jorn Piel
    Max Planck Institute for Chemical Ecology, Department of Bioorganic Chemistry, 07745 Jena, Germany
    Chembiochem 5:93-8. 2004
  4. pmc Evidence for a symbiosis island involved in horizontal acquisition of pederin biosynthetic capabilities by the bacterial symbiont of Paederus fuscipes beetles
    Jorn Piel
    Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, 07745 Jena, Germany
    J Bacteriol 186:1280-6. 2004
  5. ncbi request reprint Targeting modular polyketide synthases with iteratively acting acyltransferases from metagenomes of uncultured bacterial consortia
    Jorn Piel
    Max Planck Institute for Chemical Ecology, Department of Bioorganics, Hans Knoll Strasse 8, Beutenberg Campus, 07745 Jena, Germany
    Environ Microbiol 6:921-7. 2004
  6. pmc Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei
    Jorn Piel
    Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, Hans Knoll Strasse 8, Beutenberg Campus, 07745 Jena, Germany
    Proc Natl Acad Sci U S A 101:16222-7. 2004
  7. doi request reprint Insights into the biosynthesis of hormaomycin, an exceptionally complex bacterial signaling metabolite
    Ivonne Höfer
    Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, 07745 Jena, Germany
    Chem Biol 18:381-91. 2011
  8. ncbi request reprint A novel Dps-type protein from insect gut bacteria catalyses hydrolysis and synthesis of N-acyl amino acids
    Liyan Ping
    Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, Hans Knöll Str 8, 07745 Jena, Germany
    Environ Microbiol 9:1572-83. 2007

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Metabolites from symbiotic bacteria
    Jorn Piel
    Max Planck Institute for Chemical Ecology, Department of Bioorganic Chemistry, Hans Knoll Strasse 8, Beutenberg Campus, 07745 Jena, Germany
    Nat Prod Rep 21:519-38. 2004
    ..This review describes natural products that are shown or suspected to be synthesized by symbiotic bacteria. It includes 349 references and covers the literature in this field through 2003...
  2. pmc A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles
    Jorn Piel
    Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, Winzerlaer Strasse 10, Beutenberg Campus, 07745 Jena, Germany
    Proc Natl Acad Sci U S A 99:14002-7. 2002
    ..The unexpected presence of additional polyketide synthase/nonribosomal peptide synthetase modules reveals surprising insights into the evolutionary relationship between pederin-type pathways in beetles and sponges...
  3. ncbi request reprint Unprecedented diversity of catalytic domains in the first four modules of the putative pederin polyketide synthase
    Jorn Piel
    Max Planck Institute for Chemical Ecology, Department of Bioorganic Chemistry, 07745 Jena, Germany
    Chembiochem 5:93-8. 2004
    ..With this work, all putative pederin genes have been identified. Their heterologous expression in a culturable bacterium will provide important insights into how sustainable sources of invertebrate-derived drug candidates can be created...
  4. pmc Evidence for a symbiosis island involved in horizontal acquisition of pederin biosynthetic capabilities by the bacterial symbiont of Paederus fuscipes beetles
    Jorn Piel
    Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, 07745 Jena, Germany
    J Bacteriol 186:1280-6. 2004
    ..A horizontal transfer of genes for the biosynthesis of protective substances could explain the widespread occurrence of pederin-type compounds in unrelated animals from diverse habitats...
  5. ncbi request reprint Targeting modular polyketide synthases with iteratively acting acyltransferases from metagenomes of uncultured bacterial consortia
    Jorn Piel
    Max Planck Institute for Chemical Ecology, Department of Bioorganics, Hans Knoll Strasse 8, Beutenberg Campus, 07745 Jena, Germany
    Environ Microbiol 6:921-7. 2004
    ..To demonstrate its practical value, we located two pederin-type PKS systems putatively involved in the biosynthesis of antitumour polyketides in the metagenomic DNA of beetles, sponges and their uncultivated bacterial symbionts...
  6. pmc Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei
    Jorn Piel
    Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, Hans Knoll Strasse 8, Beutenberg Campus, 07745 Jena, Germany
    Proc Natl Acad Sci U S A 101:16222-7. 2004
    ....
  7. doi request reprint Insights into the biosynthesis of hormaomycin, an exceptionally complex bacterial signaling metabolite
    Ivonne Höfer
    Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, 07745 Jena, Germany
    Chem Biol 18:381-91. 2011
    ..The NRPS contains numerous highly repetitive regions that suggest an evolutionary scenario for this unusual bacterial hormone, providing new opportunities for evolution-inspired metabolic engineering of novel nonribosomal peptides...
  8. ncbi request reprint A novel Dps-type protein from insect gut bacteria catalyses hydrolysis and synthesis of N-acyl amino acids
    Liyan Ping
    Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, Hans Knöll Str 8, 07745 Jena, Germany
    Environ Microbiol 9:1572-83. 2007
    ..The participation of a microbial enzyme in the homeostasis of N-acyl-glutamines in the insect gut adds further complexity to the interaction between plants and their herbivores...