Laurence Pelletier

Summary

Affiliation: Max Planck Institute of Molecular Cell Biology and Genetics
Country: Germany

Publications

  1. ncbi request reprint Golgi and centrosome cycles in Toxoplasma gondii
    Jan Hartmann
    Department of Cell Biology, Ludwig Institute for Cancer Research, Yale University School of Medicine, New Haven, CT 06520, USA
    Mol Biochem Parasitol 145:125-7. 2006
  2. ncbi request reprint Genome-scale RNAi profiling of cell division in human tissue culture cells
    Ralf Kittler
    Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D 01307 Dresden, Germany
    Nat Cell Biol 9:1401-12. 2007
  3. ncbi request reprint Systems biology of mammalian cell division
    Ralf Kittler
    Department of Human Genetics and Institute of Genomics and Systems Biology, The University of Chicago, Chicago, Illinois, USA
    Cell Cycle 7:2123-8. 2008
  4. ncbi request reprint Centriole assembly in Caenorhabditis elegans
    Laurence Pelletier
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
    Nature 444:619-23. 2006
  5. ncbi request reprint The Caenorhabditis elegans centrosomal protein SPD-2 is required for both pericentriolar material recruitment and centriole duplication
    Laurence Pelletier
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
    Curr Biol 14:863-73. 2004
  6. pmc RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells
    Ralf Kittler
    Max Planck Institute for Molecular Cell Biology and Genetics, 01307 Dresden, Germany
    Proc Natl Acad Sci U S A 102:2396-401. 2005
  7. pmc Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis
    Kazuhisa Kinoshita
    Max Planck Institute of Molecular Cell Biology and Genetics MPI CBG, 01307 Dresden, Germany
    J Cell Biol 170:1047-55. 2005
  8. pmc BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals
    Ina Poser
    Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D 01307 Dresden, Germany
    Nat Methods 5:409-15. 2008
  9. ncbi request reprint An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division
    Ralf Kittler
    Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D 01307 Dresden, Germany
    Nature 432:1036-40. 2004
  10. ncbi request reprint Centriole assembly requires both centriolar and pericentriolar material proteins
    Alexander Dammermann
    Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Dev Cell 7:815-29. 2004

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Golgi and centrosome cycles in Toxoplasma gondii
    Jan Hartmann
    Department of Cell Biology, Ludwig Institute for Cancer Research, Yale University School of Medicine, New Haven, CT 06520, USA
    Mol Biochem Parasitol 145:125-7. 2006
  2. ncbi request reprint Genome-scale RNAi profiling of cell division in human tissue culture cells
    Ralf Kittler
    Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D 01307 Dresden, Germany
    Nat Cell Biol 9:1401-12. 2007
    ..Our work provides an experimental framework from which the systematic analysis of novel genes necessary for cell division in human cells can begin...
  3. ncbi request reprint Systems biology of mammalian cell division
    Ralf Kittler
    Department of Human Genetics and Institute of Genomics and Systems Biology, The University of Chicago, Chicago, Illinois, USA
    Cell Cycle 7:2123-8. 2008
    ..While a fully integrated model of mammalian cell division remains a distant goal, a framework of a systems understanding of this medically relevant process is beginning to emerge...
  4. ncbi request reprint Centriole assembly in Caenorhabditis elegans
    Laurence Pelletier
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
    Nature 444:619-23. 2006
    ..These results define a structural pathway for the assembly of a daughter centriole and should have general relevance for future studies on centriole assembly in other organisms...
  5. ncbi request reprint The Caenorhabditis elegans centrosomal protein SPD-2 is required for both pericentriolar material recruitment and centriole duplication
    Laurence Pelletier
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
    Curr Biol 14:863-73. 2004
    ..To date, however, the molecular mechanisms that govern these two processes still remain poorly understood...
  6. pmc RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells
    Ralf Kittler
    Max Planck Institute for Molecular Cell Biology and Genetics, 01307 Dresden, Germany
    Proc Natl Acad Sci U S A 102:2396-401. 2005
    ..We show that this technique can be extended to allow the creation of tagged transgenes, expressed at physiological levels, for the further study of gene function...
  7. pmc Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis
    Kazuhisa Kinoshita
    Max Planck Institute of Molecular Cell Biology and Genetics MPI CBG, 01307 Dresden, Germany
    J Cell Biol 170:1047-55. 2005
    ..We propose that Aurora A regulation of TACC3 activity defines a centrosome-specific mechanism for regulation of microtubule polymerization in mitosis...
  8. pmc BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals
    Ina Poser
    Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D 01307 Dresden, Germany
    Nat Methods 5:409-15. 2008
    ..The same high-throughput approach will be generally applicable to other model systems...
  9. ncbi request reprint An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division
    Ralf Kittler
    Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D 01307 Dresden, Germany
    Nature 432:1036-40. 2004
    ..Thus, our study uncovers new aspects of cell division and establishes esiRNA as a versatile approach for genomic RNAi screens in mammalian cells...
  10. ncbi request reprint Centriole assembly requires both centriolar and pericentriolar material proteins
    Alexander Dammermann
    Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Dev Cell 7:815-29. 2004
    ..Thus, both centriolar and pericentriolar material proteins contribute to centriole assembly...
  11. doi request reprint The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis
    Fei Zhu
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada
    Curr Biol 18:136-41. 2008
    ..Both proteins are then required for NEDD-1 recruitment and the subsequent assembly of gamma-TuRCs and other factors into fully functional centrosomes...
  12. pmc Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
    Nadine K Kolas
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto M5G1X5, Ontario, Canada
    Science 318:1637-40. 2007
    ..These results demonstrate how the DNA-damage response is orchestrated by ATM-dependent phosphorylation of MDC1 and RNF8-mediated ubiquitination...
  13. pmc Transferrin receptor recycling in the absence of perinuclear recycling endosomes
    David Sheff
    Department of Cell Biology, Ludwig Institute for Cancer Research, Yale University School of Medicine, New Haven, CT 06520
    J Cell Biol 156:797-804. 2002
    ....
  14. ncbi request reprint Centrioles: duplicating precariously
    Laurence Pelletier
    Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada
    Curr Biol 17:R770-3. 2007
    ..Recent work showing that the overexpression of centriolar proteins can lead to the formation of multiple centrioles in the absence of pre-existing centrioles challenges the idea that it is a self-replicating organelle...
  15. ncbi request reprint Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I
    Christian G Riedel
    Research Institute of Molecular Pathology IMP, Dr Bohr Gasse 7, A 1030 Vienna, Austria
    Nature 441:53-61. 2006
    ..Our data are consistent with the notion that efficient cleavage of Rec8 requires phosphorylation of cohesin and that this is blocked by PP2A at meiosis I centromeres...
  16. ncbi request reprint Golgin tethers define subpopulations of COPI vesicles
    Jorg Malsam
    Department of Cell Biology, Ludwig Institute for Cancer Research, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520 8002, USA
    Science 307:1095-8. 2005
    ..Microinjected golgin-84 or CASP also inhibited Golgi-enzyme transport to the endoplasmic reticulum, further implicating this tether in retrograde transport. These and other golgins may modulate the flow patterns within the Golgi stack...
  17. ncbi request reprint Golgi biogenesis in Toxoplasma gondii
    Laurence Pelletier
    Department of Cell Biology, Ludwig Institute for Cancer Research, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Nature 418:548-52. 2002
    ..Our results indicate that new Golgi grow by autonomous duplication and raise the possibility that the Golgi is a paired structure that is analogous to centrioles...
  18. doi request reprint Centrosomes: keeping tumors in check
    Laurence Pelletier
    Samuel Lunenfeld Research Institute, Toronto, Ontario M5G 1X5, Canada
    Curr Biol 18:R702-4. 2008
    ..Recent work in Drosophila suggests that centrosome defects in asymmetrically dividing cells can induce tumors at a higher frequency than other conditions known to cause genomic instability...