F Ohl

Summary

Affiliation: Max Planck Institute of Psychiatry
Country: Germany

Publications

  1. ncbi request reprint Dimensions of emotionality in a rat model of innate anxiety
    F Ohl
    Behavioral Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
    Behav Neurosci 115:429-36. 2001
  2. ncbi request reprint The modified hole board as a differential screen for behavior in rodents
    F Ohl
    Max Planck Institute of Psychiatry, Kraepelinstr 2, D 80804 Munich, Germany
    Behav Res Methods Instrum Comput 33:392-7. 2001
  3. ncbi request reprint Cognitive performance in rats differing in their inborn anxiety
    Frauke Ohl
    Behavioral Phenotyping, Max Planck Institute of Psychiatry, Munich, Germany
    Behav Neurosci 116:464-71. 2002
  4. ncbi request reprint Behavioural screening in mutagenised mice--in search for novel animal models of psychiatric disorders
    Frauke Ohl
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804, Munich, Germany
    Eur J Pharmacol 480:219-28. 2003
  5. ncbi request reprint Impact of high and low anxiety on cognitive performance in a modified hole board test in C57BL/6 and DBA/2 mice
    Frauke Ohl
    Max Planck Institute of Psychiatry, Kraepelinstr 2, D 80804 Munich, Germany
    Eur J Neurosci 17:128-36. 2003
  6. doi request reprint Long-term anxiolytic and antidepressant-like behavioural effects of tiagabine, a selective GABA transporter-1 (GAT-1) inhibitor, coincide with a decrease in HPA system activity in C57BL/6 mice
    C K Thoeringer
    Max Planck Institute of Psychiatry, Munich, Germany
    J Psychopharmacol 24:733-43. 2010
  7. doi request reprint Consequences of chronic social stress on behaviour and vasopressin gene expression in the PVN of DBA/2OlaHsd mice--influence of treatment with the CRHR1-antagonist R121919/NBI 30775
    A Erhardt
    MD Max Planck Institute of Psychiatry, Munich, Germany
    J Psychopharmacol 23:31-9. 2009
  8. ncbi request reprint Differential analysis of behavior and diazepam-induced alterations in C57BL/6N and BALB/c mice using the modified hole board test
    F Ohl
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, D 80804 Munich, Germany
    J Psychiatr Res 35:147-54. 2001
  9. ncbi request reprint Unconditioned anxiety and social behaviour in two rat lines selectively bred for high and low anxiety-related behaviour
    M S Henniger
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804, Munich, Germany
    Behav Brain Res 111:153-63. 2000
  10. ncbi request reprint Repetitive transcranial magnetic stimulation increases the release of dopamine in the mesolimbic and mesostriatal system
    M E Keck
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804, Munich, Germany
    Neuropharmacology 43:101-9. 2002

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Dimensions of emotionality in a rat model of innate anxiety
    F Ohl
    Behavioral Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
    Behav Neurosci 115:429-36. 2001
    ..The approach used might help to develop specific treatment strategies for anxiety disorders...
  2. ncbi request reprint The modified hole board as a differential screen for behavior in rodents
    F Ohl
    Max Planck Institute of Psychiatry, Kraepelinstr 2, D 80804 Munich, Germany
    Behav Res Methods Instrum Comput 33:392-7. 2001
    ..Therefore, the mHB represents an alternative to the common practice of using a series of more specific tests...
  3. ncbi request reprint Cognitive performance in rats differing in their inborn anxiety
    Frauke Ohl
    Behavioral Phenotyping, Max Planck Institute of Psychiatry, Munich, Germany
    Behav Neurosci 116:464-71. 2002
    ....
  4. ncbi request reprint Behavioural screening in mutagenised mice--in search for novel animal models of psychiatric disorders
    Frauke Ohl
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804, Munich, Germany
    Eur J Pharmacol 480:219-28. 2003
    ..Different strategies are being introduced, which are used in ENU-mutagenesis screens to identify behavioural mutants representing possible endophenotypes of psychiatric diseases...
  5. ncbi request reprint Impact of high and low anxiety on cognitive performance in a modified hole board test in C57BL/6 and DBA/2 mice
    Frauke Ohl
    Max Planck Institute of Psychiatry, Kraepelinstr 2, D 80804 Munich, Germany
    Eur J Neurosci 17:128-36. 2003
    ..Our findings support the idea that high anxiety may interact with specific cognitive processing, thus offering a promising animal model for future preclinical research on the interaction of anxiety and cognition...
  6. doi request reprint Long-term anxiolytic and antidepressant-like behavioural effects of tiagabine, a selective GABA transporter-1 (GAT-1) inhibitor, coincide with a decrease in HPA system activity in C57BL/6 mice
    C K Thoeringer
    Max Planck Institute of Psychiatry, Munich, Germany
    J Psychopharmacol 24:733-43. 2010
    ..This data indicate that both acute and long-term anxiolytic and antidepressant-like properties of brain GAT-1 inhibition coincide with a reduction in HPA system activity in mice...
  7. doi request reprint Consequences of chronic social stress on behaviour and vasopressin gene expression in the PVN of DBA/2OlaHsd mice--influence of treatment with the CRHR1-antagonist R121919/NBI 30775
    A Erhardt
    MD Max Planck Institute of Psychiatry, Munich, Germany
    J Psychopharmacol 23:31-9. 2009
    ....
  8. ncbi request reprint Differential analysis of behavior and diazepam-induced alterations in C57BL/6N and BALB/c mice using the modified hole board test
    F Ohl
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, D 80804 Munich, Germany
    J Psychiatr Res 35:147-54. 2001
    ..Therefore, this new strategy allows to reduce the number of experimental animals and the time needed, thus, representing an effective screening-tool for behavioral investigations...
  9. ncbi request reprint Unconditioned anxiety and social behaviour in two rat lines selectively bred for high and low anxiety-related behaviour
    M S Henniger
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804, Munich, Germany
    Behav Brain Res 111:153-63. 2000
    ....
  10. ncbi request reprint Repetitive transcranial magnetic stimulation increases the release of dopamine in the mesolimbic and mesostriatal system
    M E Keck
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804, Munich, Germany
    Neuropharmacology 43:101-9. 2002
    ..This increase in dopaminergic neurotransmission may contribute to the beneficial effects of rTMS in the treatment of affective disorders and Parkinson's disease...
  11. ncbi request reprint Maternal defence as an emotional stressor in female rats: correlation of neuroendocrine and behavioural parameters and involvement of brain oxytocin
    I D Neumann
    Max Planck Institute of Psychiatry, Kraepelinstr 2, D80804 Munich, Germany
    Eur J Neurosci 13:1016-24. 2001
    ....
  12. ncbi request reprint Differential disinhibition of the neonatal hypothalamic- pituitary-adrenal axis in brain-specific CRH receptor 1-knockout mice
    M V Schmidt
    Max Planck Institute of Psychiatry, RG Molecular Stress Physiology, Kraepelinstr 2 10, 80804 Munich, Germany
    Eur J Neurosci 24:2291-8. 2006
    ....
  13. ncbi request reprint Reduction of hypothalamic vasopressinergic hyperdrive contributes to clinically relevant behavioral and neuroendocrine effects of chronic paroxetine treatment in a psychopathological rat model
    Martin E Keck
    Max Planck Institute of Psychiatry, Munich, Germany
    Neuropsychopharmacology 28:235-43. 2003
    ..This novel mechanism of action of paroxetine on vasopressin gene regulation renders vasopressinergic neuronal circuits a promising target for the development of more causal antidepressant treatment strategies...
  14. doi request reprint Chromosomal assignment of quantitative trait loci influencing modified hole board behavior in laboratory mice using consomic strains, with special reference to anxiety-related behavior and mouse chromosome 19
    Marijke C Laarakker
    Department of Animals, Science and Society, Division of Laboratory Animal Science, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 2, P O Box 80166, 3508 TD Utrecht, The Netherlands
    Behav Genet 38:159-84. 2008
    ..CSS-19 (C57BL/6J-Chr19(A)/NaJ) differed in avoidance behavior from the C57BL/6J, but not in locomotion. Thus pleiotropic contribution of locomotion could be excluded...
  15. ncbi request reprint The temporal dynamics of intrahippocampal corticosterone in response to stress-related stimuli with different emotional and physical load: an in vivo microdialysis study in C57BL/6 and DBA/2 inbred mice
    Christoph K Thoeringer
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Psychoneuroendocrinology 32:746-57. 2007
    ..In addition, our study highlights the use of in vivo microdialysis to assess the neuroendocrine endophenotype of animal models via profiling of stimulus-response patterns of stress hormones...
  16. ncbi request reprint Effects of light or dark phase testing on behavioural and cognitive performance in DBA mice
    Angelika Roedel
    Behavioural Phenotyping, Max Planck Institute of Psychiatry, Kraepelinstr 2, D 80804 Munich, Germany
    Lab Anim 40:371-81. 2006
    ..From the results we conclude that testing during the light phase induces a pronounced behavioural inhibition as well as a cognitive disruption in DBA mice, which should be taken into account when cognitively testing these animals...
  17. ncbi request reprint A pharmacological model for psychosis based on N-methyl-D-aspartate receptor hypofunction: molecular, cellular, functional and behavioral abnormalities
    Dan Rujescu
    Division of Molecular and Clinical Neurobiology, Department of Psychiatry, Ludwig Maximilians University, Munich, Germany
    Biol Psychiatry 59:721-9. 2006
    ....
  18. ncbi request reprint Listening to mutant mice: a spotlight on the role of CRF/CRF receptor systems in affective disorders
    Martin E Keck
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Neurosci Biobehav Rev 29:867-89. 2005
    ....
  19. ncbi request reprint Differences in serotonergic neurotransmission between rats displaying high or low anxiety/depression-like behaviour: effects of chronic paroxetine treatment
    Martin E Keck
    Max Planck Institute of Psychiatry, Munich, Germany
    J Neurochem 92:1170-9. 2005
    ..Chronic paroxetine enhanced the presynaptic responsivity in HAB rats, but not LAB rats, pointing to a preferential efficacy of paroxetine in rats with enhanced anxiety/depression-related behaviour...
  20. ncbi request reprint Identification of molecules potentially involved in mediating the in vivo actions of the corticotropin-releasing hormone receptor 1 antagonist, NBI30775 (R121919)
    Anke Post
    Max Planck Institute of Psychiatry, Kraepelinstrasse 10, 80804 Munich, Germany
    Psychopharmacology (Berl) 180:150-8. 2005
    ..Despite its therapeutic efficacy, there is only little information about its mechanisms of action on cellular and molecular targets...
  21. ncbi request reprint Mechanisms underlying the protective potential of alpha-tocopherol (vitamin E) against haloperidol-associated neurotoxicity
    Anke Post
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Neuropsychopharmacology 26:397-407. 2002
    ..Collectively, the data indicate the usefulness of vitamin E as an adjunct to haloperidol treatment and provide initial clues about the underlying molecular mechanisms involved in these effects...
  22. ncbi request reprint Activity patterns as a correlate for sleep-wake behaviour in mice
    Corinna Storch
    Section of Behavioural Phenotyping, Max Planck Institute of Psychiatry, Kraepelinstr 2, 80804 Munich, Germany
    J Neurosci Methods 133:173-9. 2004
    ..In summary, this minimum invasive method allows for the detection of quantitative alterations in sleep-wake behaviour in mice, thus, offering a useful, rapid pre-screen in animal sleep research...
  23. ncbi request reprint Regular voluntary exercise reduces anxiety-related behaviour and impulsiveness in mice
    Elke Binder
    Section of Behavioral Phenotyping, Max Planck Institute of Psychiatry, Munich D 80804, Germany
    Behav Brain Res 155:197-206. 2004
    ..Thus, our observations fit into the concept that regular exercise strengthens endogenous stress coping mechanisms, thereby protecting the organism against the deleterious effects of stress...
  24. ncbi request reprint Introducing the German Mouse Clinic: open access platform for standardized phenotyping
    Valerie Gailus-Durner
    Nat Methods 2:403-4. 2005
  25. ncbi request reprint Pathological anxiety in animals
    Frauke Ohl
    Department of Animals, Science and Society, Division of Laboratory Animal Science, Veterinary Faculty, Utrecht University, P O Box 80166, 3508 TD Utrecht, Netherlands
    Vet J 175:18-26. 2008
    ....