Hellmuth Obrig

Summary

Affiliation: Max Planck Institute for Human Cognitive and Brain Sciences
Country: Germany

Publications

  1. doi request reprint NIRS in clinical neurology - a 'promising' tool?
    Hellmuth Obrig
    Clinic for Cognitive Neurology, University Clinic Leipzig, Leipzig, Germany Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany Dept Neurology, Charite, University Medicine Berlin, Berlin, Germany Electronic address
    Neuroimage 85:535-46. 2014
  2. doi request reprint Non-invasive optical imaging of stroke
    Hellmuth Obrig
    Department of Cognitive Neurology, University Hospital Leipzig, Liebigstraße 16, 04103 Leipzig, Germany
    Philos Trans A Math Phys Eng Sci 369:4470-94. 2011
  3. ncbi request reprint Cytochrome-c-oxidase redox changes during visual stimulation measured by near-infrared spectroscopy cannot be explained by a mere cross talk artefact
    Kamil Uludag
    Department of Neurology, Charite, Humboldt University, Berlin 10117, Germany
    Neuroimage 22:109-19. 2004
  4. ncbi request reprint Separability and cross talk: optimizing dual wavelength combinations for near-infrared spectroscopy of the adult head
    Kamil Uludag
    Department of Neurology, Charite, Humboldt University, Berlin 10117, Germany
    Neuroimage 22:583-9. 2004
  5. ncbi request reprint Correlates of alpha rhythm in functional magnetic resonance imaging and near infrared spectroscopy
    Matthias Moosmann
    Department of Neurology, Charite, Humboldt University, Berlin, Germany
    Neuroimage 20:145-58. 2003
  6. ncbi request reprint Towards a standard analysis for functional near-infrared imaging
    Matthias L Schroeter
    Day Clinic of Cognitive Neurology, University of Leipzig, 04103, Leipzig, Germany
    Neuroimage 21:283-90. 2004
  7. doi request reprint Stimulus-induced and state-dependent sustained gamma activity is tightly coupled to the hemodynamic response in humans
    Stefan P Koch
    Berlin NeuroImaging Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Neurosci 29:13962-70. 2009
  8. doi request reprint Implicit processing of phonotactic cues: evidence from electrophysiological and vascular responses
    Sonja Rossi
    Charite University Medicine, Berlin, Germany
    J Cogn Neurosci 23:1752-64. 2011
  9. ncbi request reprint Are VEP correlated fast optical signals detectable in the human adult by non-invasive nearinfrared spectroscopy (NIRS)?
    Frank Syré
    Neurologische Klinik, Charite, Humboldt Universitat zu Berlin, 10098 Berlin, Germany
    Adv Exp Med Biol 530:421-31. 2003
  10. doi request reprint Developmental changes in brain activation and functional connectivity during response inhibition in the early childhood brain
    Jan Mehnert
    Berlin NeuroImaging Center, Department of Neurology, Charite University Medicine, Chariteplatz 1, 10117 Berlin, Germany Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstrasse 1a, 04103 Leipzig, Germany Department of Machine Learning, Institute of Technology, Franklinstrasse 28 29, 10587 Berlin, Germany Department of Brain and Cognitive Engineering, Korea University, Anam Dong, Seongbuk gu, Seoul 136 713, Republic of Korea
    Brain Dev 35:894-904. 2013

Detail Information

Publications20

  1. doi request reprint NIRS in clinical neurology - a 'promising' tool?
    Hellmuth Obrig
    Clinic for Cognitive Neurology, University Clinic Leipzig, Leipzig, Germany Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany Dept Neurology, Charite, University Medicine Berlin, Berlin, Germany Electronic address
    Neuroimage 85:535-46. 2014
    ..Additionally the potential to exploit the established position of NIRS as a functional imaging tool with regard to clinical questions such as preoperative functional assessment and neurorehabilitation is discussed. ..
  2. doi request reprint Non-invasive optical imaging of stroke
    Hellmuth Obrig
    Department of Cognitive Neurology, University Hospital Leipzig, Liebigstraße 16, 04103 Leipzig, Germany
    Philos Trans A Math Phys Eng Sci 369:4470-94. 2011
    ....
  3. ncbi request reprint Cytochrome-c-oxidase redox changes during visual stimulation measured by near-infrared spectroscopy cannot be explained by a mere cross talk artefact
    Kamil Uludag
    Department of Neurology, Charite, Humboldt University, Berlin 10117, Germany
    Neuroimage 22:109-19. 2004
    ..Further (invasive) validation studies are required...
  4. ncbi request reprint Separability and cross talk: optimizing dual wavelength combinations for near-infrared spectroscopy of the adult head
    Kamil Uludag
    Department of Neurology, Charite, Humboldt University, Berlin 10117, Germany
    Neuroimage 22:583-9. 2004
    ..We show the relevance of these theoretical results for noninvasive NIRS by testing the predictions on experimental data obtained in adults undergoing visual stimulation...
  5. ncbi request reprint Correlates of alpha rhythm in functional magnetic resonance imaging and near infrared spectroscopy
    Matthias Moosmann
    Department of Neurology, Charite, Humboldt University, Berlin, Germany
    Neuroimage 20:145-58. 2003
    ..Our data suggest that alpha activity in the occipital cortex is associated with metabolic deactivation. Mapping of spontaneously synchronizing distributed neuronal networks is thus shown to be feasible...
  6. ncbi request reprint Towards a standard analysis for functional near-infrared imaging
    Matthias L Schroeter
    Day Clinic of Cognitive Neurology, University of Leipzig, 04103, Leipzig, Germany
    Neuroimage 21:283-90. 2004
    ....
  7. doi request reprint Stimulus-induced and state-dependent sustained gamma activity is tightly coupled to the hemodynamic response in humans
    Stefan P Koch
    Berlin NeuroImaging Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Neurosci 29:13962-70. 2009
    ....
  8. doi request reprint Implicit processing of phonotactic cues: evidence from electrophysiological and vascular responses
    Sonja Rossi
    Charite University Medicine, Berlin, Germany
    J Cogn Neurosci 23:1752-64. 2011
    ..Differential brain responses between known and unknown phonotactic rules thus supply evidence for an implicit use of phonotactic cues to guide lexical activation mechanisms...
  9. ncbi request reprint Are VEP correlated fast optical signals detectable in the human adult by non-invasive nearinfrared spectroscopy (NIRS)?
    Frank Syré
    Neurologische Klinik, Charite, Humboldt Universitat zu Berlin, 10098 Berlin, Germany
    Adv Exp Med Biol 530:421-31. 2003
    ..Also they are so small that they are below the noise level of the presently available NIRS monitors...
  10. doi request reprint Developmental changes in brain activation and functional connectivity during response inhibition in the early childhood brain
    Jan Mehnert
    Berlin NeuroImaging Center, Department of Neurology, Charite University Medicine, Chariteplatz 1, 10117 Berlin, Germany Max Planck Institute for Human Cognitive and Brain Sciences, Stephanstrasse 1a, 04103 Leipzig, Germany Department of Machine Learning, Institute of Technology, Franklinstrasse 28 29, 10587 Berlin, Germany Department of Brain and Cognitive Engineering, Korea University, Anam Dong, Seongbuk gu, Seoul 136 713, Republic of Korea
    Brain Dev 35:894-904. 2013
    ..Our findings show that in children aged from 4 to 6 years fronto-parietal brain maturation plays a crucial part in the cognitive development of response inhibition...
  11. pmc Towards whole-body fluorescence imaging in humans
    Sophie K Piper
    Department of Neurology, Charite University Medicine Berlin, Berlin, Germany Machine Learning Department, Berlin Institute of Technology, Berlin, Germany Center for Stroke Research, Charite University Medicine Berlin, Berlin, Germany
    PLoS ONE 8:e83749. 2013
    ..Since the whole-body approach demonstrates sensitivity to circumscribed alterations in skinperfusion, it may be used to target autonomous changes in polyneuropathy and to screen for peripheral vascular diseases. ..
  12. ncbi request reprint Relevance of depth resolution for cerebral blood flow monitoring by near-infrared spectroscopic bolus tracking during cardiopulmonary bypass
    Jens Steinbrink
    Clinic of Neurology, German Heart Institute, Berlin, Germany
    J Thorac Cardiovasc Surg 132:1172-8. 2006
    ..Contamination of the cerebral signal by contamination from overlaying extracerebral tissue, however, has been proposed to reduce sensitivity and cerebral selectivity of this promising technique...
  13. ncbi request reprint Neurovascular coupling analyzed non-invasively in the human brain
    Bruno Marcel Mackert
    Neurophysics Group, Department of Neurology, Campus Benjamin Franklin, Charite, University Medicine Berlin, Freie Universitat, Hindenburgdamm 30, 12200 Berlin, Germany
    Neuroreport 15:63-6. 2004
    ....
  14. doi request reprint Facilitation of inferior frontal cortex by transcranial direct current stimulation induces perceptual learning of severely degraded speech
    Bernhard Sehm
    Department of Neurology, and Max Planck Research Group Auditory Cognition, Max Planck Institute for Human Cognitive and Brain Sciences, 04103 Leipzig, Germany, Clinic of Cognitive Neurology, University of Leipzig, 04103 Leipzig, Germany, and Department of Linguistics, University of Erfurt, 99089 Erfurt, Germany
    J Neurosci 33:15868-78. 2013
    ..Our results supply first evidence that neural facilitation of higher-order language areas can induce perceptual learning of severely degraded speech...
  15. ncbi request reprint Beyond the visible--imaging the human brain with light
    Hellmuth Obrig
    Department of Neurology, Charite, Humboldt University, Berlin, Germany
    J Cereb Blood Flow Metab 23:1-18. 2003
    ..The authors conclude that NIRS imaging has two major advantages: it can address issues concerning neurovascular coupling in the human adult and can extend functional imaging approaches to the investigation of the diseased brain...
  16. doi request reprint Electrophysiological evidence for modulation of lexical processing after repetitive exposure to foreign phonotactic rules
    Sonja Rossi
    Clinic for Cognitive Neurology, University Hospital Leipzig, Medical Faculty, University of Leipzig, Liebigstr 18, D 04103 Leipzig, Germany Max Planck Institute for Human Cognitive and Brain Sciences, Department of Neurology, Stephanstr 1a, D 04103 Leipzig, Germany Electronic address
    Brain Lang 127:404-14. 2013
    ..On the contrary, Categorization Training introduces a 'protosemantic' context overriding prelexical selection processes. ..
  17. ncbi request reprint Habituation of the visually evoked potential and its vascular response: implications for neurovascular coupling in the healthy adult
    Hellmuth Obrig
    Neurologische Klinik, Charite, Humboldt Universitat zu Berlin, 10098 Berlin, Germany
    Neuroimage 17:1-18. 2002
    ....
  18. ncbi request reprint The processing of prosody: Evidence of interhemispheric specialization at the age of four
    Isabell Wartenburger
    Berlin NeuroImaging Center and Department of Neurology, Charite University Medicine Berlin, Campus Mitte, Berlin, Germany
    Neuroimage 34:416-25. 2007
    ..e. prosodic) information. Generally in accordance with the imaging data reported in adults, our finding underlines the notion that interhemispheric specialization is a continuous process during the development of language...
  19. pmc Focal retrograde amnesia: voxel-based morphometry findings in a case without MRI lesions
    Bernhard Sehm
    Clinic of Cognitive Neurology, University of Leipzig, Leipzig, Germany
    PLoS ONE 6:e26538. 2011
    ..Beyond the implications for the diagnosis and etiology of FRA, our results advocate the use of VBM in conditions that do not show abnormalities in clinical radiological assessment, but show distinct neuropsychological deficits...
  20. doi request reprint Learning by doing? The effect of gestures on implicit retrieval of newly acquired words
    Klaus Martin Krönke
    Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany Electronic address
    Cortex 49:2553-68. 2013
    ..The findings are discussed regarding their implications for theoretical accounts and for empirical approaches of gesture-based strategies in language (re)learning. ..