Knud H Nierhaus
Affiliation: Max Planck Institute for Molecular Genetics
Nierhaus K. Mg2+, K+, and the ribosome. J Bacteriol. 2014;196:3817-9 pubmed publisher
..Akanuma et al., J. Bacteriol. 196:3820-3830, 2014, doi:10.1128/JB.01896-14) report a surprising genetic link between ribosome amounts per cell and the intracellular Mg(2+) concentrations. ..
Achenbach J, Jahnz M, Bethge L, Paal K, Jung M, Schuster M, et al
. Outwitting EF-Tu and the ribosome: translation with d-amino acids. Nucleic Acids Res. 2015;43:5687-98 pubmed publisher
..Furthermore, ribosomal incorporation of d-aa into polypeptides may greatly expand the armamentarium of in vitro translation towards the identification of peptides and proteins with new properties and functions. ..
Nikolay R, Schmidt S, Schlömer R, Deuerling E, Nierhaus K. Ribosome Assembly as Antimicrobial Target. Antibiotics (Basel). 2016;5: pubmed publisher
..Furthermore, we present an in vivo screening strategy that focuses on ribosome assembly by a direct fluorescence based read-out that aims to identify and characterize small molecules acting as primary assembly inhibitors. ..
Achenbach J, Nierhaus K. The mechanics of ribosomal translocation. Biochimie. 2015;114:80-9 pubmed publisher
..This review inspects and surveys these achievements. ..