Patrick Muller

Summary

Affiliation: Max Planck Institute for Biological Cybernetics
Country: Germany

Publications

  1. pmc Morphogen transport
    Patrick Muller
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Development 140:1621-38. 2013
  2. pmc Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system
    Patrick Muller
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Science 336:721-4. 2012
  3. pmc Extracellular movement of signaling molecules
    Patrick Muller
    Department of Molecular and Cellular Biology, Harvard Stem Cell Institute, Broad Institute, Center for Brain Science, FAS Center for Systems Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Dev Cell 21:145-58. 2011

Detail Information

Publications3

  1. pmc Morphogen transport
    Patrick Muller
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Development 140:1621-38. 2013
    ..We propose that most of the available data support the idea that morphogen gradients form by diffusion that is hindered by tortuosity and binding to extracellular molecules...
  2. pmc Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system
    Patrick Muller
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Science 336:721-4. 2012
    ..These results indicate that differential diffusivity is the major determinant of the differences in Nodal/Lefty range and provide biophysical support for reaction-diffusion models of activator/inhibitor-mediated patterning...
  3. pmc Extracellular movement of signaling molecules
    Patrick Muller
    Department of Molecular and Cellular Biology, Harvard Stem Cell Institute, Broad Institute, Center for Brain Science, FAS Center for Systems Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Dev Cell 21:145-58. 2011
    ..We discuss how signals are modified and assembled for transport, which routes they take to reach their targets, and how their range is affected by mobility and stability...