Matthias Meyer

Summary

Affiliation: Max Planck Institute for Evolutionary Anthropology
Country: Germany

Publications

  1. ncbi Illumina sequencing library preparation for highly multiplexed target capture and sequencing
    Matthias Meyer
    Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Cold Spring Harb Protoc 2010:pdb.prot5448. 2010
  2. ncbi A genomic region evolving toward different GC contents in humans and chimpanzees indicates a recent and regionally limited shift in the mutation pattern
    Ingo Ebersberger
    Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    Mol Biol Evol 22:1240-5. 2005
  3. ncbi Targeted high-throughput sequencing of tagged nucleic acid samples
    Matthias Meyer
    Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
    Nucleic Acids Res 35:e97. 2007
  4. ncbi Parallel tagged sequencing on the 454 platform
    Matthias Meyer
    Max Planck Institute for Evolutionary Anthropology, Department of Evolutionary Genetics, Deutscher Platz 6, D 04103 Leipzig, Germany
    Nat Protoc 3:267-78. 2008
  5. ncbi A high-coverage genome sequence from an archaic Denisovan individual
    Matthias Meyer
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Science 338:222-6. 2012
  6. ncbi A phylogenetic estimate for golden moles (Mammalia, Afrotheria, Chrysochloridae)
    Robert J Asher
    Department of Zoology, University of Cambridge, Cambridge, UK
    BMC Evol Biol 10:69. 2010
  7. ncbi From micrograms to picograms: quantitative PCR reduces the material demands of high-throughput sequencing
    Matthias Meyer
    Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
    Nucleic Acids Res 36:e5. 2008
  8. ncbi A draft sequence of the Neandertal genome
    Richard E Green
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Science 328:710-22. 2010
  9. ncbi Targeted investigation of the Neandertal genome by array-based sequence capture
    Hernán A Burbano
    Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Science 328:723-5. 2010
  10. ncbi Road blocks on paleogenomes--polymerase extension profiling reveals the frequency of blocking lesions in ancient DNA
    Patricia Heyn
    Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
    Nucleic Acids Res 38:e161. 2010

Detail Information

Publications19

  1. ncbi Illumina sequencing library preparation for highly multiplexed target capture and sequencing
    Matthias Meyer
    Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Cold Spring Harb Protoc 2010:pdb.prot5448. 2010
    ..Libraries can be prepared from any type of double-stranded DNA, even if present in subnanogram quantity...
  2. ncbi A genomic region evolving toward different GC contents in humans and chimpanzees indicates a recent and regionally limited shift in the mutation pattern
    Ingo Ebersberger
    Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    Mol Biol Evol 22:1240-5. 2005
    ..Based on our analysis, we suggest a recent and species-specific shift in the region's mutation pattern as the cause of its differing evolution in humans and chimpanzees...
  3. ncbi Targeted high-throughput sequencing of tagged nucleic acid samples
    Matthias Meyer
    Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
    Nucleic Acids Res 35:e97. 2007
    ..PTS dramatically increases the sequencing throughput of samples in parallel and thus fully mobilizes the resources of the 454 technology for targeted sequencing...
  4. ncbi Parallel tagged sequencing on the 454 platform
    Matthias Meyer
    Max Planck Institute for Evolutionary Anthropology, Department of Evolutionary Genetics, Deutscher Platz 6, D 04103 Leipzig, Germany
    Nat Protoc 3:267-78. 2008
    ..Most of the reactions can be performed in a multichannel setup on 96-well reaction plates, allowing for processing up to several hundreds of samples in a few days...
  5. ncbi A high-coverage genome sequence from an archaic Denisovan individual
    Matthias Meyer
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Science 338:222-6. 2012
    ....
  6. ncbi A phylogenetic estimate for golden moles (Mammalia, Afrotheria, Chrysochloridae)
    Robert J Asher
    Department of Zoology, University of Cambridge, Cambridge, UK
    BMC Evol Biol 10:69. 2010
    ..Here, we use a combined analysis of partial sequences of the nuclear GHR gene and morphological characters to derive a phylogeny of species in the family Chrysochloridae...
  7. ncbi From micrograms to picograms: quantitative PCR reduces the material demands of high-throughput sequencing
    Matthias Meyer
    Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
    Nucleic Acids Res 36:e5. 2008
    ..The method should also apply to Illumina/Solexa and ABI/SOLiD sequencing, and should therefore help to widen the accessibility of all three platforms...
  8. ncbi A draft sequence of the Neandertal genome
    Richard E Green
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Science 328:710-22. 2010
    ....
  9. ncbi Targeted investigation of the Neandertal genome by array-based sequence capture
    Hernán A Burbano
    Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Science 328:723-5. 2010
    ..By generating the sequence of one Neandertal and 50 present-day humans at these positions, we have identified 88 amino acid substitutions that have become fixed in humans since our divergence from the Neandertals...
  10. ncbi Road blocks on paleogenomes--polymerase extension profiling reveals the frequency of blocking lesions in ancient DNA
    Patricia Heyn
    Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
    Nucleic Acids Res 38:e161. 2010
    ....
  11. ncbi Removal of deaminated cytosines and detection of in vivo methylation in ancient DNA
    Adrian W Briggs
    Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Nucleic Acids Res 38:e87. 2010
    ..In addition, our results demonstrate that Neandertal DNA retains in vivo patterns of CpG methylation, potentially allowing future studies of gene inactivation and imprinting in ancient organisms...
  12. ncbi A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing
    Richard E Green
    Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Cell 134:416-26. 2008
    ..There is evidence that purifying selection in the Neandertal mtDNA was reduced compared with other primate lineages, suggesting that the effective population size of Neandertals was small...
  13. ncbi Patterns of damage in genomic DNA sequences from a Neandertal
    Adrian W Briggs
    Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
    Proc Natl Acad Sci U S A 104:14616-21. 2007
    ..The results suggest that reliable genome sequences can be obtained from Pleistocene organisms...
  14. ncbi Direct multiplex sequencing (DMPS)--a novel method for targeted high-throughput sequencing of ancient and highly degraded DNA
    Mathias Stiller
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    Genome Res 19:1843-8. 2009
    ..Embedded in our approach, we present a new protocol for the construction of barcoded sequencing libraries, which is compatible with all current high-throughput technologies and can be performed entirely in plate setup...
  15. ncbi A recent evolutionary change affects a regulatory element in the human FOXP2 gene
    Tomislav Maricic
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    Mol Biol Evol 30:844-52. 2013
    ....
  16. ncbi Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform
    Martin Kircher
    Max Planck Institute for Evolutionary Anthropology, Department of Evolutionary Genetics, 04103 Leipzig, Germany
    Nucleic Acids Res 40:e3. 2012
    ..Double-indexing eliminates these problems and increases both the scope and accuracy of multiplex sequencing on the Illumina platform...
  17. ncbi Single-stranded DNA library preparation for the sequencing of ancient or damaged DNA
    Marie Theres Gansauge
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    Nat Protoc 8:737-48. 2013
    ..We estimate that intact DNA strands are recovered in the library with ∼50% efficiency. Libraries can be generated from up to 12 DNA or oligonucleotide samples in parallel within 2 d...
  18. ncbi Length and GC-biases during sequencing library amplification: a comparison of various polymerase-buffer systems with ancient and modern DNA sequencing libraries
    Jesse Dabney
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    Biotechniques 52:87-94. 2012
    ....
  19. ncbi Multiplex amplification of ancient DNA
    Holger Römpler
    Molecular Biochemistry, Institute of Biochemistry, Medical Faculty, University of Leipzig, Johannisallee 30, 04103 Leipzig, Germany
    Nat Protoc 1:720-8. 2006
    ..It thus combines optimal template usage with a high specificity and can be performed within a day...