Verena Lohr

Summary

Affiliation: Max Planck Institute for Dynamics of Complex Technical Systems
Country: Germany

Publications

  1. pmc Live attenuated influenza viruses produced in a suspension process with avian AGE1.CR.pIX cells
    Verena Lohr
    Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstr 1, 39106 Magdeburg, Germany
    BMC Biotechnol 12:79. 2012
  2. doi request reprint New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: studies on growth, metabolism and virus propagation
    V Lohr
    Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Sandtorstr 1, 39106 Magdeburg, Germany
    Vaccine 27:4975-82. 2009
  3. ncbi request reprint A new MDCK suspension line cultivated in a fully defined medium in stirred-tank and wave bioreactor
    V Lohr
    Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Sandtorstr 1, 39106 Magdeburg, Germany
    Vaccine 28:6256-64. 2010
  4. pmc Metabolic and kinetic analyses of influenza production in perfusion HEK293 cell culture
    Emma Petiot
    Biotechnology Research Institute, 6100 Royalmount Avenue, Montreal, H4P 2R2 Quebec, Canada
    BMC Biotechnol 11:84. 2011
  5. pmc The avian cell line AGE1.CR.pIX characterized by metabolic flux analysis
    Verena Lohr
    Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstr, 1, 39106 Magdeburg, Germany
    BMC Biotechnol 14:72. 2014

Collaborators

Detail Information

Publications5

  1. pmc Live attenuated influenza viruses produced in a suspension process with avian AGE1.CR.pIX cells
    Verena Lohr
    Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstr 1, 39106 Magdeburg, Germany
    BMC Biotechnol 12:79. 2012
    ..In the near future influenza vaccines for human use will also be available from adherent MDCK or Vero cell cultures, but a scalable suspension process may facilitate production and supply with vaccines...
  2. doi request reprint New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: studies on growth, metabolism and virus propagation
    V Lohr
    Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Sandtorstr 1, 39106 Magdeburg, Germany
    Vaccine 27:4975-82. 2009
    ..CR.pIX, respectively. Both viruses were produced to high titres (3.5 logHA/100 microL for influenza virus, 3.2x10(8)pfu/mL for MVA). Hence, the CR cell lines are an appropriate substrate for pharmaceutical influenza and MVA production...
  3. ncbi request reprint A new MDCK suspension line cultivated in a fully defined medium in stirred-tank and wave bioreactor
    V Lohr
    Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Sandtorstr 1, 39106 Magdeburg, Germany
    Vaccine 28:6256-64. 2010
    ..Overall, the MDCK.SUS2 cell line represents a new cell substrate for a robust influenza vaccine production in a fully defined process...
  4. pmc Metabolic and kinetic analyses of influenza production in perfusion HEK293 cell culture
    Emma Petiot
    Biotechnology Research Institute, 6100 Royalmount Avenue, Montreal, H4P 2R2 Quebec, Canada
    BMC Biotechnol 11:84. 2011
    ..In the same study, it was suggested that beyond 4 × 10(6) cells/mL, viral production was limited by a lack of nutrients or an accumulation of toxic products...
  5. pmc The avian cell line AGE1.CR.pIX characterized by metabolic flux analysis
    Verena Lohr
    Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstr, 1, 39106 Magdeburg, Germany
    BMC Biotechnol 14:72. 2014
    ..Therefore, we derived previously a continuous suspension cell line, AGE1.CR.pIX, from muscovy duck and established chemically-defined media for virus propagation...