Mingkun Li

Summary

Affiliation: Max Planck Institute for Evolutionary Anthropology
Country: Germany

Publications

  1. pmc Fidelity of capture-enrichment for mtDNA genome sequencing: influence of NUMTs
    Mingkun Li
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D04103, Leipzig, Germany
    Nucleic Acids Res 40:e137. 2012
  2. pmc A new approach for detecting low-level mutations in next-generation sequence data
    Mingkun Li
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D04103, Leipzig, Germany
    Genome Biol 13:R34. 2012
  3. pmc Detecting heteroplasmy from high-throughput sequencing of complete human mitochondrial DNA genomes
    Mingkun Li
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D04103 Leipzig, Germany
    Am J Hum Genet 87:237-49. 2010
  4. pmc The tendency to recreate ancestral CG dinucleotides in the human genome
    Mingkun Li
    CAS MPG Partner Institute of Computational Biology, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, 200000 Shanghai, PR China
    BMC Evol Biol 11:3. 2011
  5. pmc Early Austronesians: into and out of Taiwan
    Albert Min Shan Ko
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany
    Am J Hum Genet 94:426-36. 2014
  6. pmc High diversity of the saliva microbiome in Batwa Pygmies
    Ivan Nasidze
    Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    PLoS ONE 6:e23352. 2011
  7. pmc The saliva microbiome of Pan and Homo
    Jing Li
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig D 04103, Germany
    BMC Microbiol 13:204. 2013
  8. doi request reprint Contrasting maternal and paternal histories in the linguistic context of Burkina Faso
    Chiara Barbieri
    Max Planck Research Group on Comparative Population Linguistics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    Mol Biol Evol 29:1213-23. 2012
  9. pmc High-throughput sequencing of complete human mtDNA genomes from the Caucasus and West Asia: high diversity and demographic inferences
    Anna Schönberg
    Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig, Germany
    Eur J Hum Genet 19:988-94. 2011
  10. doi request reprint Larger mitochondrial DNA than Y-chromosome differences between matrilocal and patrilocal groups from Sumatra
    Ellen Dröfn Gunnarsdóttir
    Department of Evolutionary Anthropology, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    Nat Commun 2:228. 2011

Collaborators

Detail Information

Publications13

  1. pmc Fidelity of capture-enrichment for mtDNA genome sequencing: influence of NUMTs
    Mingkun Li
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D04103, Leipzig, Germany
    Nucleic Acids Res 40:e137. 2012
    ..g. heteroplasmy) is more challenging. We develop here a computational method to distinguish NUMT alleles from heteroplasmies, using sequence data from artificial mixtures to optimize the method...
  2. pmc A new approach for detecting low-level mutations in next-generation sequence data
    Mingkun Li
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D04103, Leipzig, Germany
    Genome Biol 13:R34. 2012
    ..In addition, we also discuss other problems in detecting low-level mutations, including chimeric reads and sample cross-contamination, and provide possible solutions to them...
  3. pmc Detecting heteroplasmy from high-throughput sequencing of complete human mitochondrial DNA genomes
    Mingkun Li
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D04103 Leipzig, Germany
    Am J Hum Genet 87:237-49. 2010
    ..With appropriate criteria for avoiding false positives due to sequencing errors, next-generation technologies can provide novel insights into genome-wide aspects of mtDNA heteroplasmy...
  4. pmc The tendency to recreate ancestral CG dinucleotides in the human genome
    Mingkun Li
    CAS MPG Partner Institute of Computational Biology, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, 200000 Shanghai, PR China
    BMC Evol Biol 11:3. 2011
    ..How these two conflicting processes regarding the fate of CG dinucleotides - i.e., high mutation rate destroying CG dinucleotides, vs. functional processes that require their preservation remains an unsolved question...
  5. pmc Early Austronesians: into and out of Taiwan
    Albert Min Shan Ko
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig 04103, Germany
    Am J Hum Genet 94:426-36. 2014
    ....
  6. pmc High diversity of the saliva microbiome in Batwa Pygmies
    Ivan Nasidze
    Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    PLoS ONE 6:e23352. 2011
    ..The distinctive composition of the salvia microbiome of the Batwa may have been influenced by their recent different lifestyle and diet...
  7. pmc The saliva microbiome of Pan and Homo
    Jing Li
    Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig D 04103, Germany
    BMC Microbiol 13:204. 2013
    ....
  8. doi request reprint Contrasting maternal and paternal histories in the linguistic context of Burkina Faso
    Chiara Barbieri
    Max Planck Research Group on Comparative Population Linguistics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    Mol Biol Evol 29:1213-23. 2012
    ..However, subsequent climatic fluctuations do not appear to have had an impact on the demography of the inhabitants of West Africa, probably reflecting the adaptive advantages of cultural innovations, such as pastoralism and agriculture...
  9. pmc High-throughput sequencing of complete human mtDNA genomes from the Caucasus and West Asia: high diversity and demographic inferences
    Anna Schönberg
    Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig, Germany
    Eur J Hum Genet 19:988-94. 2011
    ..These results illustrate the value of random sampling of complete mtDNA genome sequences that can be obtained with high-throughput sequencing platforms...
  10. doi request reprint Larger mitochondrial DNA than Y-chromosome differences between matrilocal and patrilocal groups from Sumatra
    Ellen Dröfn Gunnarsdóttir
    Department of Evolutionary Anthropology, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    Nat Commun 2:228. 2011
    ..We highlight the importance of using complete mtDNA sequences for such analyses, as using only partial sequences (as done in previous studies) can give misleading results...
  11. pmc High-throughput sequencing of complete human mtDNA genomes from the Philippines
    Ellen D Gunnarsdóttir
    Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Genome Res 21:1-11. 2011
    ..Our results clearly demonstrate that the high-throughput sequencing platforms are the methodology of choice for generating complete mtDNA genome sequences...
  12. pmc Complete mtDNA genomes of Filipino ethnolinguistic groups: a melting pot of recent and ancient lineages in the Asia-Pacific region
    Frederick Delfin
    1 Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz, Leipzig, Germany 2 DNA Analysis Laboratory, Natural Sciences Research Institute, University of the Philippines, Diliman, Quezon City, Philippines
    Eur J Hum Genet 22:228-37. 2014
    ....
  13. doi request reprint Comparative analysis of human saliva microbiome diversity by barcoded pyrosequencing and cloning approaches
    Ivan Nasidze
    Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
    Anal Biochem 391:64-8. 2009
    ....