Eckhard Lammert

Summary

Affiliation: Max Planck Institute of Molecular Cell Biology and Genetics
Country: Germany

Publications

  1. ncbi request reprint Role of endothelial cells in early pancreas and liver development
    Eckhard Lammert
    Department of Molecular and Cellular Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA
    Mech Dev 120:59-64. 2003
  2. ncbi request reprint Role of VEGF-A in vascularization of pancreatic islets
    Eckhard Lammert
    Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany
    Curr Biol 13:1070-4. 2003
  3. doi request reprint The vascular trigger of type II diabetes mellitus
    E Lammert
    Max Planck Institute of Molecular Cell Biology and Genetics and Institute of Animal Physiology, Heinrich Heine University, Dusseldorf, Germany
    Exp Clin Endocrinol Diabetes 116:S21-5. 2008
  4. ncbi request reprint The vascular niche and its basement membrane
    Ganka Nikolova
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr 108, D 01307 Dresden, Germany
    Trends Cell Biol 17:19-25. 2007
  5. ncbi request reprint Vascular lumen formation from a cell biological perspective
    Tomas Kucera
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr 108, D 01307 Dresden, Germany
    Novartis Found Symp 283:46-56; discussion 56-60, 238-41. 2007
  6. ncbi request reprint The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation
    Ganka Nikolova
    Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany
    Dev Cell 10:397-405. 2006
  7. ncbi request reprint Interdependent development of blood vessels and organs
    Ganka Nikolova
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasssse 108, 01307, Dresden, Germany
    Cell Tissue Res 314:33-42. 2003
  8. ncbi request reprint EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets
    Irena Konstantinova
    Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany
    Cell 129:359-70. 2007
  9. pmc Mechanoinduction of lymph vessel expansion
    Lara Planas-Paz
    Institute of Metabolic Physiology, Heinrich Heine University, Dusseldorf, Germany
    EMBO J 31:788-804. 2012
  10. doi request reprint A new collagenase blend increases the number of islets isolated from mouse pancreas
    Pinar Yesil
    Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
    Islets 1:185-90. 2009

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Role of endothelial cells in early pancreas and liver development
    Eckhard Lammert
    Department of Molecular and Cellular Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA
    Mech Dev 120:59-64. 2003
    ..This review summarizes reports on EC signaling during organogenesis and cell differentiation...
  2. ncbi request reprint Role of VEGF-A in vascularization of pancreatic islets
    Eckhard Lammert
    Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany
    Curr Biol 13:1070-4. 2003
    ..The second step involves paracrine VEGF-A signaling to elaborate the interaction of islets with the circulatory system...
  3. doi request reprint The vascular trigger of type II diabetes mellitus
    E Lammert
    Max Planck Institute of Molecular Cell Biology and Genetics and Institute of Animal Physiology, Heinrich Heine University, Dusseldorf, Germany
    Exp Clin Endocrinol Diabetes 116:S21-5. 2008
    ..Whereas vascular complications have been widely accepted as a result of type II diabetes, we suggest that changes within the vascular system may act at an earlier stage and trigger the onset of type II diabetes...
  4. ncbi request reprint The vascular niche and its basement membrane
    Ganka Nikolova
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr 108, D 01307 Dresden, Germany
    Trends Cell Biol 17:19-25. 2007
    ..We further propose that these cells require a vascular niche when they retain a high degree of plasticity...
  5. ncbi request reprint Vascular lumen formation from a cell biological perspective
    Tomas Kucera
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr 108, D 01307 Dresden, Germany
    Novartis Found Symp 283:46-56; discussion 56-60, 238-41. 2007
    ..In addition, we point to a number of questions that need to be addressed to understand better the cell biology that drives the formation of a vascular lumen...
  6. ncbi request reprint The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation
    Ganka Nikolova
    Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany
    Dev Cell 10:397-405. 2006
    ..The proposed mechanism explains why beta cells must interact with endothelial cells, and it may apply to other cellular processes in which endothelial signals are required...
  7. ncbi request reprint Interdependent development of blood vessels and organs
    Ganka Nikolova
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasssse 108, 01307, Dresden, Germany
    Cell Tissue Res 314:33-42. 2003
    ..Such signals give EC organ-specific features that the organ needs to interact with the circulatory system. This review provides the reader with specific examples of an interdependent development of organs and blood vessels...
  8. ncbi request reprint EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets
    Irena Konstantinova
    Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany
    Cell 129:359-70. 2007
    ..Thus, we explain how beta cell communication in pancreatic islets conversely affects basal and glucose-stimulated insulin secretion to improve glucose homeostasis...
  9. pmc Mechanoinduction of lymph vessel expansion
    Lara Planas-Paz
    Institute of Metabolic Physiology, Heinrich Heine University, Dusseldorf, Germany
    EMBO J 31:788-804. 2012
    ..Thus, we propose a new and physiologically relevant mode of VEGFR3 activation, which is based on mechanotransduction and is essential for normal development and fluid homeostasis in a mammalian embryo...
  10. doi request reprint A new collagenase blend increases the number of islets isolated from mouse pancreas
    Pinar Yesil
    Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
    Islets 1:185-90. 2009
    ..Furthermore, this study also points to a possibility to increase the number and mass of islets isolated from human pancreases, for which only a limited donor pool exists...
  11. doi request reprint Resolving cell-cell junctions: lumen formation in blood vessels
    Martin Zeeb
    Institute of Metabolic Physiology, Heinrich Heine University, Dusseldorf, Germany
    Curr Opin Cell Biol 22:626-32. 2010
    ..Here we review the role of EC junctions in vascular lumen formation within different vascular beds...
  12. doi request reprint Vascular lumen formation
    Jennifer Axnick
    Institute of Metabolic Physiology, Heinrich Heine University, Dusseldorf, Germany
    Curr Opin Hematol 19:192-8. 2012
    ..Here, we discuss the molecular and cellular mechanisms underlying vascular lumen formation in invertebrates and vertebrates and highlight a new hypothesis describing oxygen transport in human malignant tumors...
  13. doi request reprint Age- and diet-dependent requirement of DJ-1 for glucose homeostasis in mice with implications for human type 2 diabetes
    Deepak Jain
    Institute of Metabolic Physiology, Heinrich Heine University, D 40225 Dusseldorf, Germany
    J Mol Cell Biol 4:221-30. 2012
    ..Our data suggest that DJ-1 is more generally involved in age- and lifestyle-related human diseases and show for the first time that DJ-1 plays a key role in glucose homeostasis and might serve as a novel drug target for T2DM...
  14. ncbi request reprint Islet dynamics: a glimpse at beta cell proliferation
    Pinar Yesil
    Max Planck Institute of Molecular Cell Biology and Genetics MPI CBG, Dresden, Germany
    Histol Histopathol 23:883-95. 2008
    ..Once established, these methods would have profound benefits for diabetic patients...
  15. ncbi request reprint Microvascular development: learning from pancreatic islets
    Irena Konstantinova
    Max Planck Institute of Molecular Cell Biology and Genetics, Dresden Germany
    Bioessays 26:1069-75. 2004
    ..At the end, we look at the islet microvasculature from a medical point of view, thus describing its critical role during type I diabetes and islet transplantation...