Research Topics
Genomes and Genes | Johannes KrauseSummaryAffiliation: Max Planck Institute for Evolutionary Anthropology Country: Germany Publications
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Detail Information
Publications
A complete mtDNA genome of an early modern human from Kostenki, RussiaJohannes Krause
Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
Curr Biol 20:231-6. 2010..We use these features to determine a complete mtDNA sequence from a approximately 30,000-year-old EMH from the Kostenki 14 site in Russia...
Genetic characterization of the ABO blood group in NeandertalsCarles Lalueza-Fox
Institut de Biologia Evolutiva, Barcelona, Spain
BMC Evol Biol 8:342. 2008..A paleogenetic analysis of the ABO blood group gene in Neandertals allows us to directly test for the presence of the ABO alleles in these extinct humans...- The complete mitochondrial DNA genome of an unknown hominin from southern SiberiaJohannes Krause
Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
Nature 464:894-7. 2010..The stratigraphy of the cave where the bone was found suggests that the Denisova hominin lived close in time and space with Neanderthals as well as with modern humans... - Targeted retrieval and analysis of five Neandertal mtDNA genomesAdrian W Briggs
Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
Science 325:318-21. 2009..Together with analyses of mtDNA protein evolution, these data suggest that the long-term effective population size of Neandertals was smaller than that of modern humans and extant great apes... - A draft sequence of the Neandertal genomeRichard E Green
Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
Science 328:710-22. 2010.... - Targeted investigation of the Neandertal genome by array-based sequence captureHernán A Burbano
Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
Science 328:723-5. 2010..By generating the sequence of one Neandertal and 50 present-day humans at these positions, we have identified 88 amino acid substitutions that have become fixed in humans since our divergence from the Neandertals... - The Neandertal genome and ancient DNA authenticityRichard E Green
Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
EMBO J 28:2494-502. 2009..For analyses of other fossil hominins, which may become possible in the future, we suggest a similar 'boot-strap' approach in which interim approaches are applied until sufficient data for more definitive direct assays are acquired... - A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencingRichard E Green
Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
Cell 134:416-26. 2008..There is evidence that purifying selection in the Neandertal mtDNA was reduced compared with other primate lineages, suggesting that the effective population size of Neandertals was small... - Patterns of damage in genomic DNA sequences from a NeandertalAdrian W Briggs
Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
Proc Natl Acad Sci U S A 104:14616-21. 2007..The results suggest that reliable genome sequences can be obtained from Pleistocene organisms... - From micrograms to picograms: quantitative PCR reduces the material demands of high-throughput sequencingMatthias Meyer
Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
Nucleic Acids Res 36:e5. 2008..The method should also apply to Illumina/Solexa and ABI/SOLiD sequencing, and should therefore help to widen the accessibility of all three platforms... 
The derived FOXP2 variant of modern humans was shared with NeandertalsJohannes Krause
Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103 Leipzig, Germany
Curr Biol 17:1908-12. 2007..Thus, these results illustrate the usefulness of retrieving direct genetic information from ancient remains for understanding recent human evolution...- Neanderthals in central Asia and SiberiaJohannes Krause
Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
Nature 449:902-4. 2007..Thus, the geographic range of Neanderthals is likely to have extended at least 2,000 km further to the east than commonly assumed... - Removal of deaminated cytosines and detection of in vivo methylation in ancient DNAAdrian W Briggs
Max Planck Institute for Evolutionary Anthropology, D 04103 Leipzig, Germany
Nucleic Acids Res 38:e87. 2010..In addition, our results demonstrate that Neandertal DNA retains in vivo patterns of CpG methylation, potentially allowing future studies of gene inactivation and imprinting in ancient organisms... - Multiplex amplification of the mammoth mitochondrial genome and the evolution of ElephantidaeJohannes Krause
Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
Nature 439:724-7. 2006..However, the divergence of mammoth, African and Asian elephants occurred over a short time, corresponding to only about 7% of the total length of the phylogenetic tree for the three evolutionary lineages... - Complete mitochondrial genomes reveal neolithic expansion into EuropeQiaomei Fu
Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
PLoS ONE 7:e32473. 2012..Our data show that contemporary mtDNA datasets can be used to study ancient population history if only limited ancient genetic data is available... - Analysis of one million base pairs of Neanderthal DNARichard E Green
Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
Nature 444:330-6. 2006..Existing technology and fossil resources are now sufficient to initiate a Neanderthal genome-sequencing effort... - Temporal patterns of nucleotide misincorporations and DNA fragmentation in ancient DNASusanna Sawyer
Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
PLoS ONE 7:e34131. 2012..These nucleotide misincorporations are thus a useful tool to distinguish recent from ancient DNA sources in specimens that have not been subjected to unusual or harsh treatments... - Mitochondrial genomes reveal an explosive radiation of extinct and extant bears near the Miocene-Pliocene boundaryJohannes Krause
Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
BMC Evol Biol 8:220. 2008..Widely divergent topologies have been suggested based on various data sets and methods... - Genetic analyses from ancient DNASvante Paabo
Max Planck Institute for Evolutionary Anthropology, D 04013 Leipzig, Germany
Annu Rev Genet 38:645-79. 2004..We also highlight some significant results and areas of promising future research... - Learning about human population history from ancient and modern genomesMark Stoneking
Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D04103 Leipzig, Germany
Nat Rev Genet 12:603-14. 2011..These new developments promise to reveal new stories about human population history, without having to resort to storytelling... - Functional analysis of human and chimpanzee promotersFlorian Heissig
Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, D 04103 Leipzig, Germany
Genome Biol 6:R57. 2005....