Matthias Kneussel

Summary

Affiliation: Max Planck Institute for Brain Research
Country: Germany

Publications

  1. ncbi request reprint Dynamic stabilization: Structural plasticity at inhibitory postsynaptic sites
    Matthias Kneussel
    Zentrum fur Molekulare Neurobiologie Hamburg, ZMNH, Universitat Hamburg, Falkenried 94, D 20251 Hamburg, Germany
    Traffic 7:1604-6. 2006
  2. ncbi request reprint Distribution of transcripts for the brain-specific GDP/GTP exchange factor collybistin in the developing mouse brain
    M Kneussel
    Department of Neurochemistry, Max Planck Institute for Brain Research, Deutschordenstrasse 46, D 60528 Frankfurt Main, Germany
    Eur J Neurosci 13:487-92. 2001
  3. pmc Activated radixin is essential for GABAA receptor alpha5 subunit anchoring at the actin cytoskeleton
    Sven Loebrich
    Zentrum für Molekulare Neurobiologie Hamburg ZMNH, Universitat Hamburg, Hamburg, Germany
    EMBO J 25:987-99. 2006
  4. ncbi request reprint Dynamic regulation of GABA(A) receptors at synaptic sites
    Matthias Kneussel
    Department of Neurochemistry, Max Planck Institute for Brain Research, Deutschordenstrasse 46, D 60528 Frankfurt Main, Germany
    Brain Res Brain Res Rev 39:74-83. 2002
  5. ncbi request reprint Rescue of molybdenum cofactor biosynthesis in gephyrin-deficient mice by a Cnx1 transgene
    Yannick Grosskreutz
    Department of Neurochemistry, Max Planck Institute for Brain Research, Deutschordenstrasse 46, D 60528 Frankfurt Main, Germany
    Biochem Biophys Res Commun 301:450-5. 2003
  6. ncbi request reprint GABARAP is not essential for GABA receptor targeting to the synapse
    Gregory A O'Sullivan
    Department of Neurochemistry, Max Planck Institute for Brain Research, Deutschordenstrasse 46, 60528 Frankfurt, Germany
    Eur J Neurosci 22:2644-8. 2005
  7. ncbi request reprint Spontaneous synaptic activity in an organotypic culture of the mouse retina
    Jorge Pérez-León
    Department of Neuroanatomy, Max Planck Institute for Brain Research, Frankfurt M, Germany
    Invest Ophthalmol Vis Sci 44:1376-87. 2003
  8. ncbi request reprint Interaction of synaptophysin with the AP-1 adaptor protein gamma-adaptin
    Hiroshi P M Horikawa
    Department of Neurochemistry, Max Planck Institute for Brain Research, Deutschordenstrasse 46, 60528, Frankfurt, Germany
    Mol Cell Neurosci 21:454-62. 2002
  9. ncbi request reprint Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes
    Jens C Fuhrmann
    Max Planck Institute for Brain Research, Department of Neurochemistry, D 60528 Frankfurt Main, Germany
    J Neurosci 22:5393-402. 2002
  10. pmc Neuronal cotransport of glycine receptor and the scaffold protein gephyrin
    Christoph Maas
    Zentrum fur Molekulare Neurobiologie Hamburg, Universitat Hamburg, D 20251 Hamburg, Germany
    J Cell Biol 172:441-51. 2006

Collaborators

  • Oussama El Far
  • Moritz J Frech
  • Heinz Wässle
  • Stefan Kins
  • Antoine Triller
  • Joachim Kirsch
  • Zvulun Elazar
  • Andreas Bracher
  • Marco Sassoè-Pognetto
  • Glen B Banks
  • Morgan H Sheng
  • Refik Kanjhan
  • Josephine Clare Adams
  • Sven Loebrich
  • Heinrich Betz
  • Nadia Tagnaouti
  • Christoph Maas
  • Pietro Pilo Boyl
  • Patrizia Panzanelli
  • Walter Witke
  • Masahisa Horiuchi
  • Henrike Neuhoff
  • Gregory A O'Sullivan
  • Yannick Grosskreutz
  • York Rudhard
  • Jorge Pérez-León
  • Jens C Fuhrmann
  • Vassiliy N Bavro
  • Hiroshi P M Horikawa
  • Elisabeth Georges-Labouesse
  • Susanne Fehr
  • Adele De Arcangelis
  • Vivian Costantini
  • Yvonne Pechmann
  • Frank Heisler
  • Emerald Perlas
  • Alessia Di Nardo
  • Christophe Mulle
  • Maurizio Giustetto
  • Hugo Vara
  • Marzia Massimi
  • Andrea Mele
  • Bardo Behrend
  • Corinna Lappe-Siefke
  • Robert Bähring
  • Tatsuya Katsuno
  • Sachiko Tsukita
  • Johann Helmut Brandstaetter
  • Juergen Roes
  • Cezar M Tigaret
  • Kurt H Backus
  • Ralf Schoepfer
  • Alexander J Annala
  • Jörn E Schröder
  • Mohammed A Nassar
  • Georg F Rast
  • Philip E Chen
  • Isabel Dean
  • Alasdair J Gibb
  • Stephen P Hunt
  • Frauke Fischer
  • Maria Sola
  • Winfried Weissenhorn
  • Philippe Rostaing

Detail Information

Publications19

  1. ncbi request reprint Dynamic stabilization: Structural plasticity at inhibitory postsynaptic sites
    Matthias Kneussel
    Zentrum fur Molekulare Neurobiologie Hamburg, ZMNH, Universitat Hamburg, Falkenried 94, D 20251 Hamburg, Germany
    Traffic 7:1604-6. 2006
    ..Taking into account that also surface membrane receptors are highly mobile, local coincidence of receptors and scaffold elements in adjacent layers at dendritic shafts might depend on regulatory processes underlying synaptic plasticity...
  2. ncbi request reprint Distribution of transcripts for the brain-specific GDP/GTP exchange factor collybistin in the developing mouse brain
    M Kneussel
    Department of Neurochemistry, Max Planck Institute for Brain Research, Deutschordenstrasse 46, D 60528 Frankfurt Main, Germany
    Eur J Neurosci 13:487-92. 2001
    ..Our data show that collybistin expression is upregulated when neurons become postmitotic and start to differentiate...
  3. pmc Activated radixin is essential for GABAA receptor alpha5 subunit anchoring at the actin cytoskeleton
    Sven Loebrich
    Zentrum für Molekulare Neurobiologie Hamburg ZMNH, Universitat Hamburg, Hamburg, Germany
    EMBO J 25:987-99. 2006
    ..Our data suggest radixin to represent a critical factor in receptor localization and/or downstream signaling...
  4. ncbi request reprint Dynamic regulation of GABA(A) receptors at synaptic sites
    Matthias Kneussel
    Department of Neurochemistry, Max Planck Institute for Brain Research, Deutschordenstrasse 46, D 60528 Frankfurt Main, Germany
    Brain Res Brain Res Rev 39:74-83. 2002
    ..This article discusses these recent data in the field of GABA(A)R dynamics...
  5. ncbi request reprint Rescue of molybdenum cofactor biosynthesis in gephyrin-deficient mice by a Cnx1 transgene
    Yannick Grosskreutz
    Department of Neurochemistry, Max Planck Institute for Brain Research, Deutschordenstrasse 46, D 60528 Frankfurt Main, Germany
    Biochem Biophys Res Commun 301:450-5. 2003
    ..Our data suggest that the loss of neurotransmitter receptor clustering at inhibitory synapses causes the early lethality of gephyrin deficient mice...
  6. ncbi request reprint GABARAP is not essential for GABA receptor targeting to the synapse
    Gregory A O'Sullivan
    Department of Neurochemistry, Max Planck Institute for Brain Research, Deutschordenstrasse 46, 60528 Frankfurt, Germany
    Eur J Neurosci 22:2644-8. 2005
    ..Thus, GABARAP is not essential for trafficking gamma2 subunit containing GABA(A)Rs to the neuronal plasma membrane or targeting them to inhibitory synapses...
  7. ncbi request reprint Spontaneous synaptic activity in an organotypic culture of the mouse retina
    Jorge Pérez-León
    Department of Neuroanatomy, Max Planck Institute for Brain Research, Frankfurt M, Germany
    Invest Ophthalmol Vis Sci 44:1376-87. 2003
    ..After a preceding anatomic study of the synaptic development, the electrical activity of the synaptic circuits within such cultures was studied in wild-type and gephyrin-deficient mice...
  8. ncbi request reprint Interaction of synaptophysin with the AP-1 adaptor protein gamma-adaptin
    Hiroshi P M Horikawa
    Department of Neurochemistry, Max Planck Institute for Brain Research, Deutschordenstrasse 46, 60528, Frankfurt, Germany
    Mol Cell Neurosci 21:454-62. 2002
    ..Our results are consistent with synaptophysin serving as a docking site for AP-1 during clathrin-dependent vesicle budding and/or kinesin-based transport reactions...
  9. ncbi request reprint Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes
    Jens C Fuhrmann
    Max Planck Institute for Brain Research, Department of Neurochemistry, D 60528 Frankfurt Main, Germany
    J Neurosci 22:5393-402. 2002
    ..Because Dlc-1 and Dlc-2 have been described as stoichiometric components of cytoplasmic dynein and myosin-Va complexes, our results suggest that motor proteins are involved in the subcellular localization of gephyrin...
  10. pmc Neuronal cotransport of glycine receptor and the scaffold protein gephyrin
    Christoph Maas
    Zentrum fur Molekulare Neurobiologie Hamburg, Universitat Hamburg, D 20251 Hamburg, Germany
    J Cell Biol 172:441-51. 2006
    ....
  11. ncbi request reprint Cellular localization and subcellular distribution of Unc-33-like protein 6, a brain-specific protein of the collapsin response mediator protein family that interacts with the neuronal glycine transporter 2
    Masahisa Horiuchi
    Abteilung Neurochemie, Max Planck Institut für Hirnforschung, Frankfurt am Main, Germany
    J Neurochem 94:307-15. 2005
    ..Our data support a model in which Ulip6 transiently interacts with GlyT2 in a phosphorylation-dependent manner...
  12. ncbi request reprint Glycinergic and GABAergic synaptic activity differentially regulate motoneuron survival and skeletal muscle innervation
    Glen B Banks
    School of Biomedical Sciences, University of Queensland, St Lucia, 4072 Queensland, Australia
    J Neurosci 25:1249-59. 2005
    ....
  13. ncbi request reprint The actin-binding protein profilin I is localized at synaptic sites in an activity-regulated manner
    Henrike Neuhoff
    Zentrum fur Molekulare Neurobiologie Hamburg, ZMNH, University of Hamburg, Falkenried 94, D 20251 Hamburg, Germany
    Eur J Neurosci 21:15-25. 2005
    ..These results show that profilin I can be present at both pre- and postsynaptic sites and suggest a role for this actin-binding protein in activity-dependent remodelling of synaptic structure...
  14. pmc Crystal structure of the GABA(A)-receptor-associated protein, GABARAP
    Vassiliy N Bavro
    European Molecular Biology Laboratory EMBL, 6 rue Jules Horowitz, BP181, F 38042 Grenoble 9, France
    EMBO Rep 3:183-9. 2002
    ....
  15. pmc Postsynaptic scaffold proteins at non-synaptic sites. The role of postsynaptic scaffold proteins in motor-protein-receptor complexes
    Matthias Kneussel
    Zentrum fur Molekulare Neurobiologie Hamburg, ZMNH, Universitat Hamburg, Falkenried 94, D 20251 Hamburg, Germany
    EMBO Rep 6:22-7. 2005
    ....
  16. ncbi request reprint Absence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signaling
    York Rudhard
    Wellcome Laboratory for Molecular Pharmacology, University College London, London WC1E 6BT, United Kingdom
    J Neurosci 23:2323-32. 2003
    ..Our results show that coincidence detection by, and/or Ca2+ permeability of, NMDARs is necessary for the development of somatotopic maps in the brainstem and suggest that highly specific signaling underlies synaptic refinement...
  17. pmc Neuronal expression of muskelin in the rodent central nervous system
    Nadia Tagnaouti
    Zentrum fur Molekulare Neurobiologie Hamburg, ZMNH, Universitat Hamburg, Germany
    BMC Neurosci 8:28. 2007
    ..Since little is known about muskelin in neuronal tissues, we here analysed the tissue distribution of muskelin in rodent brain and analysed its subcellular localization using cultured neurons from multiple life stages...
  18. ncbi request reprint Trafficking and synaptic anchoring of ionotropic inhibitory neurotransmitter receptors
    Matthias Kneussel
    Zentrum fur Molekulare Neurobiologie Hamburg, ZMNH, Universitat Hamburg, Falkenried 94, Germany
    Biol Cell 99:297-309. 2007
    ..In the present review, we discuss the dynamic delivery, stabilization and removal of inhibitory receptors at synaptic sites...
  19. pmc Profilin2 contributes to synaptic vesicle exocytosis, neuronal excitability, and novelty-seeking behavior
    Pietro Pilo Boyl
    EMBL, Mouse Biology Unit, Adriano Buzzati Traverso Campus, Via Ramarini 32, 00015 Monterotondo, Italy
    EMBO J 26:2991-3002. 2007
    ..Our results highlight a novel, profilin2-dependent pathway, regulating synaptic physiology, neuronal excitability, and complex behavior...