Gaspar Jekely

Summary

Affiliation: Max Planck Institute for Biological Cybernetics
Country: Germany

Publications

  1. pmc Expression dynamics and protein localization of rhabdomeric opsins in Platynereis larvae
    Nadine Randel
    Max Planck Institute for Developmental Biology, Spemannstrasse 35, 72076 Tuebingen, Germany
    Integr Comp Biol 53:7-16. 2013
  2. pmc Global view of the evolution and diversity of metazoan neuropeptide signaling
    Gaspar Jekely
    Max Planck Institute for Developmental Biology, 72076 Tubingen, Germany
    Proc Natl Acad Sci U S A 110:8702-7. 2013
  3. pmc Whole-body gene expression pattern registration in Platynereis larvae
    Albina Asadulina
    Max Planck Institute for Developmental Biology, Spemannstrasse 35, Tubingen, 72076, Germany
    Evodevo 3:27. 2012
  4. pmc Antibodies against conserved amidated neuropeptide epitopes enrich the comparative neurobiology toolbox
    Markus Conzelmann
    Max Planck Institute for Developmental Biology, Spemannstrasse 35, Tubingen 72076, Germany
    Evodevo 3:23. 2012
  5. doi request reprint Mechanism of phototaxis in marine zooplankton
    Gaspar Jekely
    Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany
    Nature 456:395-9. 2008
  6. pmc Origin and early evolution of neural circuits for the control of ciliary locomotion
    Gaspar Jekely
    Max Planck Institute for Developmental Biology, Tubingen, Germany
    Proc Biol Sci 278:914-22. 2011
  7. pmc Evolution of phototaxis
    Gaspar Jekely
    Max Planck Institute for Developmental Biology, Spemannstrasse 35, 72076 Tubingen, Germany
    Philos Trans R Soc Lond B Biol Sci 364:2795-808. 2009
  8. pmc Origin of the nucleus and Ran-dependent transport to safeguard ribosome biogenesis in a chimeric cell
    Gaspar Jekely
    Max Planck Institute for Developmental Biology, Spemannstrasse 35 72076 Tübingen, Germany
    Biol Direct 3:31. 2008
  9. pmc Conserved MIP receptor-ligand pair regulates Platynereis larval settlement
    Markus Conzelmann
    Max Planck Institute for Developmental Biology, 72076 Tuebingen, Germany
    Proc Natl Acad Sci U S A 110:8224-9. 2013
  10. pmc Neuropeptides regulate swimming depth of Platynereis larvae
    Markus Conzelmann
    Max Planck Institute for Developmental Biology, 72076 Tubingen, Germany
    Proc Natl Acad Sci U S A 108:E1174-83. 2011

Collaborators

Detail Information

Publications21

  1. pmc Expression dynamics and protein localization of rhabdomeric opsins in Platynereis larvae
    Nadine Randel
    Max Planck Institute for Developmental Biology, Spemannstrasse 35, 72076 Tuebingen, Germany
    Integr Comp Biol 53:7-16. 2013
    ....
  2. pmc Global view of the evolution and diversity of metazoan neuropeptide signaling
    Gaspar Jekely
    Max Planck Institute for Developmental Biology, 72076 Tubingen, Germany
    Proc Natl Acad Sci U S A 110:8702-7. 2013
    ..The reconstruction of the neuropeptide-signaling repertoire at deep nodes of the animal phylogeny allowed the formulation of a testable scenario of the evolution of animal neuroendocrine systems...
  3. pmc Whole-body gene expression pattern registration in Platynereis larvae
    Albina Asadulina
    Max Planck Institute for Developmental Biology, Spemannstrasse 35, Tubingen, 72076, Germany
    Evodevo 3:27. 2012
    ..abstract:..
  4. pmc Antibodies against conserved amidated neuropeptide epitopes enrich the comparative neurobiology toolbox
    Markus Conzelmann
    Max Planck Institute for Developmental Biology, Spemannstrasse 35, Tubingen 72076, Germany
    Evodevo 3:23. 2012
    ..abstract:..
  5. doi request reprint Mechanism of phototaxis in marine zooplankton
    Gaspar Jekely
    Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany
    Nature 456:395-9. 2008
    ..We propose that the underlying direct coupling of light sensing and ciliary locomotor control was a principal feature of the proto-eye and an important landmark in the evolution of animal eyes...
  6. pmc Origin and early evolution of neural circuits for the control of ciliary locomotion
    Gaspar Jekely
    Max Planck Institute for Developmental Biology, Tubingen, Germany
    Proc Biol Sci 278:914-22. 2011
    ..The sensory-motor nervous systems of cnidarians and ciliated larvae of diverse phyla show that brains, like all biological structures, are not irreducibly complex...
  7. pmc Evolution of phototaxis
    Gaspar Jekely
    Max Planck Institute for Developmental Biology, Spemannstrasse 35, 72076 Tubingen, Germany
    Philos Trans R Soc Lond B Biol Sci 364:2795-808. 2009
    ..We can conclude that it is relatively easy to evolve phototaxis once cell polarity, ciliary swimming and a stable cell shape are present...
  8. pmc Origin of the nucleus and Ran-dependent transport to safeguard ribosome biogenesis in a chimeric cell
    Gaspar Jekely
    Max Planck Institute for Developmental Biology, Spemannstrasse 35 72076 Tübingen, Germany
    Biol Direct 3:31. 2008
    ..Such an autogenous scenario is cell biologically feasible, but it is not clear what were the selective or neutral mechanisms that had led to the origin of the nuclear compartment...
  9. pmc Conserved MIP receptor-ligand pair regulates Platynereis larval settlement
    Markus Conzelmann
    Max Planck Institute for Developmental Biology, 72076 Tuebingen, Germany
    Proc Natl Acad Sci U S A 110:8224-9. 2013
    ..We demonstrate by morpholino-mediated knockdown that MIP signals via this receptor to trigger settlement. These results reveal a role for a conserved MIP receptor-ligand pair in regulating marine annelid settlement...
  10. pmc Neuropeptides regulate swimming depth of Platynereis larvae
    Markus Conzelmann
    Max Planck Institute for Developmental Biology, 72076 Tubingen, Germany
    Proc Natl Acad Sci U S A 108:E1174-83. 2011
    ..We propose that the simple circuitry found in these ciliated larvae represents an ancestral state in nervous system evolution...
  11. ncbi request reprint Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration
    Gaspar Jekely
    Developmental Biology Program, European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Dev Cell 9:197-207. 2005
    ..Cbl and Sprint both regulate early steps of RTK endocytosis. Thus, a physiological role of RTK endocytosis is to ensure localized intracellular response to guidance cues by stimulating spatial restriction of signaling...
  12. pmc The evolution of nervous system centralization
    Detlev Arendt
    Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany
    Philos Trans R Soc Lond B Biol Sci 363:1523-8. 2008
    ..This way, different aspects of the molecular architecture of the urbilaterian nervous system are reconstructed and yield insight into the degree of centralization that was in place in the bilaterian ancestors...
  13. ncbi request reprint Origin of eukaryotic endomembranes: a critical evaluation of different model scenarios
    Gaspar Jekely
    European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Adv Exp Med Biol 607:38-51. 2007
    ..I argue that such models can best satisfy the major constraints of membrane topology, membrane heredity and straightforwardly account for selection pressures while being consistent with genomic findings...
  14. ncbi request reprint Evolution of intraflagellar transport from coated vesicles and autogenous origin of the eukaryotic cilium
    Gaspar Jekely
    European Molecular Biology Laboratory, Heidelberg, Germany
    Bioessays 28:191-8. 2006
    ..We propose a scenario for how the initial membrane patch gradually protruded to enhance exposure to the environment, then started to move, and finally compartmentalised to render receptor signalling and ciliary beating more efficient...
  15. pmc Deep transcriptome-sequencing and proteome analysis of the hydrothermal vent annelid Alvinella pompejana identifies the CvP-bias as a robust measure of eukaryotic thermostability
    Thomas Holder
    Max Planck Institute for Developmental Biology, Spemannstr, 35, Tubingen, D 72076, Germany
    Biol Direct 8:2. 2013
    ..A. pompejana is one of the most thermotolerant metazoans, making this animal a subject of great interest for studies of eukaryotic thermoadaptation...
  16. ncbi request reprint Cellular resolution expression profiling using confocal detection of NBT/BCIP precipitate by reflection microscopy
    Gaspar Jekely
    Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
    Biotechniques 42:751-5. 2007
    ..Whole-mount reflection CLSM will thus greatly facilitate large-scale cellular resolution expression profiling in vertebrate and invertebrate model organisms...
  17. ncbi request reprint Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in bilateria
    Alexandru S Denes
    Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, 69117, Germany
    Cell 129:277-88. 2007
    ..Our data indicate that this mediolateral architecture was present in the last common bilaterian ancestor and thus support a common origin of nervous system centralization in Bilateria...
  18. ncbi request reprint Small GTPases and the evolution of the eukaryotic cell
    Gaspar Jekely
    European Molecular Biology Laboratory, Developmental Biology, Meyerhofstrasse 1, 69117 Heidelberg, Germany
    Bioessays 25:1129-38. 2003
    ..Based on the reconstruction of putative roles for ancestral small GTPases, a hypothetical scenario on the origins of the first endomembranes, the nucleus, and phagocytosis is presented...
  19. pmc The neuropeptide complement of the marine annelid Platynereis dumerilii
    Markus Conzelmann
    Max Planck Institute for Developmental Biology, Spemannstrasse 35, 72076, Tubingen, Germany
    BMC Genomics 14:906. 2013
    ..Despite these advances, comprehensive peptidome resources have yet to be reported...
  20. pmc Evolution in a nutshell. EMBL PhD student symposium on evolution
    Gaspar Jekely
    European Molecular Biology Laboratory, Meyerhofstrasse 1, D 69117 Heidelberg, Germany
    EMBO Rep 3:307-11. 2002
  21. pmc Hrs mediates downregulation of multiple signalling receptors in Drosophila
    Gaspar Jekely
    European Molecular Biology Laboratory, Developmental Biology Program, Heidelberg, Germany
    EMBO Rep 4:1163-8. 2003
    ..Finally, most hrs-dependent receptor turnover appears to be ligand independent. Thus, both active and inactive signalling receptors are targeted for degradation in vivo and Hrs is required for their removal...