Sonja Horstmann

Summary

Affiliation: Max Planck Institute of Psychiatry
Country: Germany

Publications

  1. ncbi Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients
    Martin A Kohli
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, D 80804 Munich, Germany
    Arch Gen Psychiatry 67:348-59. 2010
  2. ncbi Suppressive effect of mirtazapine on the HPA system in acutely depressed women seems to be transient and not related to antidepressant action
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Psychoneuroendocrinology 34:238-48. 2009
  3. ncbi Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Munich, Germany
    Neuropsychopharmacology 35:727-40. 2010
  4. ncbi Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project
    Johannes M Hennings
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    J Psychiatr Res 43:215-29. 2009
  5. ncbi HTR2A gene variation is involved in antidepressant treatment response
    Susanne Lucae
    Max Planck Institute of Psychiatry, Munich, Germany
    Eur Neuropsychopharmacol 20:65-8. 2010
  6. ncbi A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
    Marcus Ising
    Max Planck Institute of Psychiatry, Munich 80804, Germany
    Arch Gen Psychiatry 66:966-75. 2009
  7. ncbi Overweight and obesity affect treatment response in major depression
    Stefan Kloiber
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 62:321-6. 2007
  8. ncbi Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls
    Marcus Ising
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Eur J Neurosci 28:389-98. 2008
  9. ncbi Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression - a potential biomarker?
    Marcus Ising
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 62:47-54. 2007
  10. ncbi Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients
    Angela Heck
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 150:104-14. 2009

Detail Information

Publications13

  1. ncbi Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients
    Martin A Kohli
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, D 80804 Munich, Germany
    Arch Gen Psychiatry 67:348-59. 2010
    ..Especially in suicide victims, lower postmortem brain messenger RNA and protein levels of neurotrophins and their receptors have been reported...
  2. ncbi Suppressive effect of mirtazapine on the HPA system in acutely depressed women seems to be transient and not related to antidepressant action
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Psychoneuroendocrinology 34:238-48. 2009
    ..Our results confirm that dex/CRH tests can be used as predictors of clinical course also under mirtazapine treatment...
  3. ncbi Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Munich, Germany
    Neuropsychopharmacology 35:727-40. 2010
    ....
  4. ncbi Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project
    Johannes M Hennings
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    J Psychiatr Res 43:215-29. 2009
    ..We demonstrated that this subgroup can be characterized by a set of demographic, clinical and neuroendocrine variables allowing to predict unfavorable outcome at an early stage of treatment...
  5. ncbi HTR2A gene variation is involved in antidepressant treatment response
    Susanne Lucae
    Max Planck Institute of Psychiatry, Munich, Germany
    Eur Neuropsychopharmacol 20:65-8. 2010
    ....
  6. ncbi A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
    Marcus Ising
    Max Planck Institute of Psychiatry, Munich 80804, Germany
    Arch Gen Psychiatry 66:966-75. 2009
    ..Genetic factors and clinical characteristics contribute to the failure of a favorable treatment outcome...
  7. ncbi Overweight and obesity affect treatment response in major depression
    Stefan Kloiber
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 62:321-6. 2007
    ..To elucidate the impact of weight on the course of depression beyond comorbidity, we investigated psychopathology, attention, neuroendocrinology, weight change, and treatment response in MDD patients, depending on their weight...
  8. ncbi Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls
    Marcus Ising
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Eur J Neurosci 28:389-98. 2008
    ..This reaction pattern suggests that subjects carrying these variants are at risk of displaying chronically elevated cortisol levels after repeated stress constituting a risk factor for stress-related diseases...
  9. ncbi Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression - a potential biomarker?
    Marcus Ising
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 62:47-54. 2007
    ..In the present study, we examined whether change in HPA system function during the first weeks of hospitalization predicts response to antidepressant treatment in major depression and thus constitutes a potential biomarker...
  10. ncbi Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients
    Angela Heck
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 150:104-14. 2009
    ..These results suggest that the ACE gene is involved in the development of coping strategies...
  11. ncbi Persistent cognitive impairment in depression: the role of psychopathology and altered hypothalamic-pituitary-adrenocortical (HPA) system regulation
    Simone Reppermund
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 62:400-6. 2007
    ..This study examines the associations between HPA system regulation, cognitive functioning, and psychopathology in depressed inpatients on admission and at discharge...
  12. ncbi Pharmacogenomics of antidepressant drugs
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Munich, Germany
    Pharmacol Ther 124:57-73. 2009
    ..Illustrated by examples from current candidate gene- and whole genome association studies, this manuscript critically discusses aspects of pharmacogenetic studies in antidepressant response related to study design and clinical relevance...
  13. ncbi Glucocorticoids as predictors of treatment response in depression
    Sonja Horstmann
    Max Planck Institute of Psychiatry RG Molecular Genetics of Affective Disorders, Munich, Germany
    Harv Rev Psychiatry 19:125-43. 2011
    ..The purpose of this review is to evaluate the evidence for using glucocorticoid-related measures for personalized treatment of depression...