Sonja Horstmann

Summary

Affiliation: Max Planck Institute of Psychiatry
Country: Germany

Publications

  1. pmc Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients
    Martin A Kohli
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, D 80804 Munich, Germany
    Arch Gen Psychiatry 67:348-59. 2010
  2. doi request reprint Suppressive effect of mirtazapine on the HPA system in acutely depressed women seems to be transient and not related to antidepressant action
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Psychoneuroendocrinology 34:238-48. 2009
  3. pmc Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Munich, Germany
    Neuropsychopharmacology 35:727-40. 2010
  4. doi request reprint Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project
    Johannes M Hennings
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    J Psychiatr Res 43:215-29. 2009
  5. doi request reprint A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
    Marcus Ising
    Max Planck Institute of Psychiatry, Munich 80804, Germany
    Arch Gen Psychiatry 66:966-75. 2009
  6. doi request reprint HTR2A gene variation is involved in antidepressant treatment response
    Susanne Lucae
    Max Planck Institute of Psychiatry, Munich, Germany
    Eur Neuropsychopharmacol 20:65-8. 2010
  7. ncbi request reprint Overweight and obesity affect treatment response in major depression
    Stefan Kloiber
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 62:321-6. 2007
  8. doi request reprint Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls
    Marcus Ising
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Eur J Neurosci 28:389-98. 2008
  9. doi request reprint Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients
    Angela Heck
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 150:104-14. 2009
  10. ncbi request reprint Persistent cognitive impairment in depression: the role of psychopathology and altered hypothalamic-pituitary-adrenocortical (HPA) system regulation
    Simone Reppermund
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 62:400-6. 2007

Detail Information

Publications14

  1. pmc Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients
    Martin A Kohli
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, D 80804 Munich, Germany
    Arch Gen Psychiatry 67:348-59. 2010
    ..Especially in suicide victims, lower postmortem brain messenger RNA and protein levels of neurotrophins and their receptors have been reported...
  2. doi request reprint Suppressive effect of mirtazapine on the HPA system in acutely depressed women seems to be transient and not related to antidepressant action
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Psychoneuroendocrinology 34:238-48. 2009
    ..Our results confirm that dex/CRH tests can be used as predictors of clinical course also under mirtazapine treatment...
  3. pmc Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Munich, Germany
    Neuropsychopharmacology 35:727-40. 2010
    ....
  4. doi request reprint Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project
    Johannes M Hennings
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    J Psychiatr Res 43:215-29. 2009
    ..We demonstrated that this subgroup can be characterized by a set of demographic, clinical and neuroendocrine variables allowing to predict unfavorable outcome at an early stage of treatment...
  5. doi request reprint A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
    Marcus Ising
    Max Planck Institute of Psychiatry, Munich 80804, Germany
    Arch Gen Psychiatry 66:966-75. 2009
    ..Genetic factors and clinical characteristics contribute to the failure of a favorable treatment outcome...
  6. doi request reprint HTR2A gene variation is involved in antidepressant treatment response
    Susanne Lucae
    Max Planck Institute of Psychiatry, Munich, Germany
    Eur Neuropsychopharmacol 20:65-8. 2010
    ....
  7. ncbi request reprint Overweight and obesity affect treatment response in major depression
    Stefan Kloiber
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 62:321-6. 2007
    ..To elucidate the impact of weight on the course of depression beyond comorbidity, we investigated psychopathology, attention, neuroendocrinology, weight change, and treatment response in MDD patients, depending on their weight...
  8. doi request reprint Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls
    Marcus Ising
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Eur J Neurosci 28:389-98. 2008
    ..This reaction pattern suggests that subjects carrying these variants are at risk of displaying chronically elevated cortisol levels after repeated stress constituting a risk factor for stress-related diseases...
  9. doi request reprint Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients
    Angela Heck
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 150:104-14. 2009
    ..These results suggest that the ACE gene is involved in the development of coping strategies...
  10. ncbi request reprint Persistent cognitive impairment in depression: the role of psychopathology and altered hypothalamic-pituitary-adrenocortical (HPA) system regulation
    Simone Reppermund
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 62:400-6. 2007
    ..This study examines the associations between HPA system regulation, cognitive functioning, and psychopathology in depressed inpatients on admission and at discharge...
  11. ncbi request reprint Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression - a potential biomarker?
    Marcus Ising
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 62:47-54. 2007
    ..In the present study, we examined whether change in HPA system function during the first weeks of hospitalization predicts response to antidepressant treatment in major depression and thus constitutes a potential biomarker...
  12. doi request reprint Glucocorticoids as predictors of treatment response in depression
    Sonja Horstmann
    Max Planck Institute of Psychiatry RG Molecular Genetics of Affective Disorders, Munich, Germany
    Harv Rev Psychiatry 19:125-43. 2011
    ..The purpose of this review is to evaluate the evidence for using glucocorticoid-related measures for personalized treatment of depression...
  13. doi request reprint Pharmacogenomics of antidepressant drugs
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Munich, Germany
    Pharmacol Ther 124:57-73. 2009
    ..Illustrated by examples from current candidate gene- and whole genome association studies, this manuscript critically discusses aspects of pharmacogenetic studies in antidepressant response related to study design and clinical relevance...
  14. pmc Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach
    Johannes M Hennings
    Max Planck Institute of Psychiatry, Munich, Germany
    PLoS ONE 8:e64947. 2013
    ..Genetic variations within the genes coding for the brain-derived neurotrophic factor (BDNF) and its key receptor Trkb (NTRK2) may therefore influence the response to antidepressant treatment...