Affiliation: Max Planck Institute of Molecular Cell Biology and Genetics
- Hundreds of conserved non-coding genomic regions are independently lost in mammalsMichael Hiller
Department of Developmental Biology, Stanford University, Stanford, California 94305, USA
Nucleic Acids Res 40:11463-76. 2012..Our study uncovers an interesting aspect of the evolution of functional DNA in mammalian genomes. Experiments are necessary to test if these independently lost CNEs are associated with parallel phenotype changes in mammals...
- A "forward genomics" approach links genotype to phenotype using independent phenotypic losses among related speciesMichael Hiller
Department of Developmental Biology, Stanford University, Stanford, CA 94305, USA
Cell Rep 2:817-23. 2012....
- GREAT improves functional interpretation of cis-regulatory regionsCory Y McLean
Department of Computer Science, Stanford University, Stanford, California, USA
Nat Biotechnol 28:495-501. 2010..The utility of GREAT is not limited to ChIP-seq, as it could also be applied to open chromatin, localized epigenomic markers and similar functional data sets, as well as comparative genomics sets...