Rainer Haseneder

Summary

Affiliation: Max Planck Institute of Psychiatry
Country: Germany

Publications

  1. doi request reprint The xenon-mediated antagonism against the NMDA receptor is non-selective for receptors containing either NR2A or NR2B subunits in the mouse amygdala
    Rainer Haseneder
    Department of Anaesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, 81675 Munich, Germany
    Eur J Pharmacol 619:33-7. 2009
  2. doi request reprint Xenon attenuates excitatory synaptic transmission in the rodent prefrontal cortex and spinal cord dorsal horn
    Rainer Haseneder
    Department of Anesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, 81675 Munich, Germany
    Anesthesiology 111:1297-307. 2009
  3. ncbi request reprint Isoflurane reduces glutamatergic transmission in neurons in the spinal cord superficial dorsal horn: evidence for a presynaptic site of an analgesic action
    Rainer Haseneder
    Department of Anaesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Anesth Analg 98:1718-23, table of contents. 2004
  4. doi request reprint Isoflurane and sevoflurane dose-dependently impair hippocampal long-term potentiation
    Rainer Haseneder
    Department of Anaesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, 81675 Munich, Germany
    Eur J Pharmacol 623:47-51. 2009
  5. doi request reprint Xenon reduces N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated synaptic transmission in the amygdala
    Rainer Haseneder
    Department of Anesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse22, D 81675 Munich, Germany
    Anesthesiology 109:998-1006. 2008
  6. doi request reprint Tranexamic acid impairs γ-aminobutyric acid receptor type A-mediated synaptic transmission in the murine amygdala: a potential mechanism for drug-induced seizures?
    Stephan Kratzer
    From the Department of Anesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany S K, H I, C M, M B, E K, G R, and R H Department of Anesthesiology, Deutsches Herzzentrum Munchen, Klinik an der Technischen Universität München, Munich, Germany J K and RG Neuronal Network Dynamics, Max Planck Institut of Psychiatry, Munich, Germany M E
    Anesthesiology 120:639-49. 2014
  7. doi request reprint Xenon attenuates hippocampal long-term potentiation by diminishing synaptic and extrasynaptic N-methyl-D-aspartate receptor currents
    Stephan Kratzer
    Department of Anesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Anesthesiology 116:673-82. 2012
  8. ncbi request reprint GABA(A) receptor activation and open-channel block by volatile anaesthetics: a new principle of receptor modulation?
    Rainer Haseneder
    Department of Anaesthesiology, Technische Universitat Munchen, Ismaninger Str 22, 81675 Munich, Germany
    Eur J Pharmacol 451:43-50. 2002
  9. doi request reprint Isoflurane anaesthesia reversibly improves cognitive function and long-term potentiation (LTP) via an up-regulation in NMDA receptor 2B subunit expression
    Gerhard Rammes
    Department of Anaesthesiology, Technische Universitat Munchen, D 81675 Munich, Germany
    Neuropharmacology 56:626-36. 2009
  10. ncbi request reprint Isoflurane modulates glutamatergic and GABAergic neurotransmission in the amygdala
    Andreas Ranft
    Department of Anaesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, D 81675 Munich, Germany
    Eur J Neurosci 20:1276-80. 2004

Detail Information

Publications12

  1. doi request reprint The xenon-mediated antagonism against the NMDA receptor is non-selective for receptors containing either NR2A or NR2B subunits in the mouse amygdala
    Rainer Haseneder
    Department of Anaesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, 81675 Munich, Germany
    Eur J Pharmacol 619:33-7. 2009
    ..These results provide evidence, that the Xe-induced antagonism against NMDA receptors is non-selective against NR2A- or NR2B-containing receptors...
  2. doi request reprint Xenon attenuates excitatory synaptic transmission in the rodent prefrontal cortex and spinal cord dorsal horn
    Rainer Haseneder
    Department of Anesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, 81675 Munich, Germany
    Anesthesiology 111:1297-307. 2009
    ..In the current study, the authors examined the effects of xenon on synaptic transmission in the prefrontal cortex and the spinal cord dorsal horn (substantia gelatinosa)...
  3. ncbi request reprint Isoflurane reduces glutamatergic transmission in neurons in the spinal cord superficial dorsal horn: evidence for a presynaptic site of an analgesic action
    Rainer Haseneder
    Department of Anaesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Anesth Analg 98:1718-23, table of contents. 2004
    ..This effect may contribute to an antinociceptive action of volatile anesthetics at the spinal cord level...
  4. doi request reprint Isoflurane and sevoflurane dose-dependently impair hippocampal long-term potentiation
    Rainer Haseneder
    Department of Anaesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, 81675 Munich, Germany
    Eur J Pharmacol 623:47-51. 2009
    ..7-fold (1.7- and 2.2-fold) MAC, LTP was blocked. Our results indicate, that both anaesthetics influence synaptic strength to a similar degree, with only high concentrations blocking hippocampal CA1 stratum radiatum long-term potentiation...
  5. doi request reprint Xenon reduces N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated synaptic transmission in the amygdala
    Rainer Haseneder
    Department of Anesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse22, D 81675 Munich, Germany
    Anesthesiology 109:998-1006. 2008
    ..In the current study, the authors evaluated for the first time the effect of xenon on synaptic transmission in the basolateral amygdala in an in vitro brain slice preparation of the mouse...
  6. doi request reprint Tranexamic acid impairs γ-aminobutyric acid receptor type A-mediated synaptic transmission in the murine amygdala: a potential mechanism for drug-induced seizures?
    Stephan Kratzer
    From the Department of Anesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany S K, H I, C M, M B, E K, G R, and R H Department of Anesthesiology, Deutsches Herzzentrum Munchen, Klinik an der Technischen Universität München, Munich, Germany J K and RG Neuronal Network Dynamics, Max Planck Institut of Psychiatry, Munich, Germany M E
    Anesthesiology 120:639-49. 2014
    ..The neuronal mechanisms underlying this proconvulsant action of TXA are not fully understood. In this study, the authors investigated the effects of TXA on neuronal excitability and synaptic transmission in the basolateral amygdala...
  7. doi request reprint Xenon attenuates hippocampal long-term potentiation by diminishing synaptic and extrasynaptic N-methyl-D-aspartate receptor currents
    Stephan Kratzer
    Department of Anesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    Anesthesiology 116:673-82. 2012
    ..In hippocampal brain slices, the authors investigated in area CA1 whether xenon affects LTP, NMDA receptor-mediated neurotransmission, and intracellular calcium concentrations...
  8. ncbi request reprint GABA(A) receptor activation and open-channel block by volatile anaesthetics: a new principle of receptor modulation?
    Rainer Haseneder
    Department of Anaesthesiology, Technische Universitat Munchen, Ismaninger Str 22, 81675 Munich, Germany
    Eur J Pharmacol 451:43-50. 2002
    ..Open-channel blocks might also be operative in other ligand-gated ion channels to modulate synaptic strength...
  9. doi request reprint Isoflurane anaesthesia reversibly improves cognitive function and long-term potentiation (LTP) via an up-regulation in NMDA receptor 2B subunit expression
    Gerhard Rammes
    Department of Anaesthesiology, Technische Universitat Munchen, D 81675 Munich, Germany
    Neuropharmacology 56:626-36. 2009
    ..The present data suggests that isoflurane anaesthesia induces a hippocampus-specific elevation of NR2B subunit composition, enhances LTP in CA1 neurones, and produces hippocampal-dependent cognitive improvement...
  10. ncbi request reprint Isoflurane modulates glutamatergic and GABAergic neurotransmission in the amygdala
    Andreas Ranft
    Department of Anaesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Ismaninger Strasse 22, D 81675 Munich, Germany
    Eur J Neurosci 20:1276-80. 2004
    ..The present results may contribute to the understanding of how stress reactions and long-lasting neuroplastic processes are suppressed under general anaesthesia...
  11. pmc Sevoflurane anesthesia improves cognitive performance in mice, but does not influence in vitro long-term potentation in hippocampus CA1 stratum radiatum
    Rainer Haseneder
    Department of Anesthesiology, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany
    PLoS ONE 8:e64732. 2013
    ..In this study, we investigated the impact of sevoflurane anesthesia on cognitive performance and cellular mechanisms involved in learning and memory...
  12. ncbi request reprint Cloned human and murine serotonin(3A) receptors expressed in human embryonic kidney 293 cells display different single-channel kinetics
    Gerhard Hapfelmeier
    Department of Anaesthesiology, Technische Universitat Munchen, Munich, Germany
    Neurosci Lett 335:44-8. 2002
    ..1+/-2.9 ms vs. 4.1+/-0.8 ms) indicating species-dependent gating mechanisms of 5-HT(3) receptors...