Affiliation: Max Planck Institute for Molecular Genetics
- MetaReg: a platform for modeling, analysis and visualization of biological systems using large-scale experimental dataIgor Ulitsky
School of Computer Science, Tel Aviv University, Tel Aviv 69978, Israel
Genome Biol 9:R1. 2008..By summarizing prior knowledge and providing visual and computational aids, it helps the expert explore and understand her system better...
- Evidence for gene-specific rather than transcription rate-dependent histone H3 exchange in yeast coding regionsIrit Gat-Viks
Computational Molecular Biology Department, Max Planck Institute for Molecular Genetics, Berlin, Germany
PLoS Comput Biol 5:e1000282. 2009..Therefore, our results that gene-specific coding region histone H3 exchange is decoupled from transcription rate might hint at a new epigenetic mechanism of transcription regulation...
- Deregulation upon DNA damage revealed by joint analysis of context-specific perturbation dataEwa Szczurek
Computational Molecular Biology Department, Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
BMC Bioinformatics 12:249. 2011..Accumulating knowledge about biological networks creates an opportunity to study these changes in their cellular context...
- Elucidating regulatory mechanisms downstream of a signaling pathway using informative experimentsEwa Szczurek
Computational Molecular Biology Department, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany
Mol Syst Biol 5:287. 2009..In comparison with other approaches, MEED suggested the most informative experiments for unambiguous identification of transcriptional regulation in this system...