Ann E Ehrenhofer-Murray
Affiliation: Max Planck Institute for Molecular Genetics
- Interactions within the mammalian DNA methyltransferase familyJean B Margot
Ludwig Maximilians University, Department of Biology II, Goethestr, 31, D 80336 Munich, Germany
BMC Mol Biol 4:7. 2003..Deletion analysis has revealed that a large part of the N-terminal domain is required for enzymatic activity...
- Dependence of ORC silencing function on NatA-mediated Nalpha acetylation in Saccharomyces cerevisiaeAntje Geissenhöner
Otto Warburg Laboratorium, Max Planck Institut fur Molekulare Genetik, Ihnestr 73, D 14195 Berlin, Germany
Mol Cell Biol 24:10300-12. 2004..In summary, we propose a model by which N(alpha) acetylation is required for the binding of silencing factors to the N terminus of Orc1p and Sir3p to recruit heterochromatic factors and establish repression...
- Chromatin dynamics at DNA replication, transcription and repairAnn E Ehrenhofer-Murray
Otto Warburg Laboratories, Max Planck Institute of Molecular Genetics, Berlin, Germany
Eur J Biochem 271:2335-49. 2004..This review will summarize the current knowledge of how chromatin remodeling and histone modifying complexes cooperate to break and remake chromatin during nuclear processes on the DNA template...
- Control of replication initiation and heterochromatin formation in Saccharomyces cerevisiae by a regulator of meiotic gene expressionHorst Irlbacher
Otto Warburg Laboratorium and Department for Computational Molecular Biology, Max Planck Institut fur Molekulare Genetik, D 14195 Berlin, Germany
Genes Dev 19:1811-22. 2005..Full initiation activity of these origins required Sum1, and their origin activity was decreased upon removal of the Sum1-binding site. Thus, Sum1 constitutes a novel global regulator of replication initiation in yeast...
- Nuclear import of the histone acetyltransferase complex SAS-I in Saccharomyces cerevisiaeSigrid Schaper
Otto Warburg Laboratories, Max Planck Institute of Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
J Cell Sci 118:1473-84. 2005..A database search based on the aligned consensus sequence revealed potential new import substrates of the Kap123p and Pse1p nuclear import pathways, which are connected to chromatin function...
- Genome-wide H4 K16 acetylation by SAS-I is deposited independently of transcription and histone exchangeFranziska Heise
Zentrum für Medizinische Biotechnologie, Abteilung Genetik, Universitat Duisburg Essen, Essen, Germany
Nucleic Acids Res 40:65-74. 2012....
- SIR-dependent repression of non-telomeric genes in Saccharomyces cerevisiae?Uta Marchfelder
Otto Warburg Laboratories, Max Planck Institut fur Molekulare Genetik, D 14195 Berlin, Germany
Yeast 20:797-801. 2003..However, we were unable to verify their SIR-dependent regulation, which suggests that SIR-mediated repression may be restricted to the known repressed regions...
- The effect of micrococcal nuclease digestion on nucleosome positioning dataHo Ryun Chung
Department of Computational Molecular Biology, MPI für Molekulare Genetik, Berlin, Germany
PLoS ONE 5:e15754. 2010..More generally, our results show that data generated after MNase digestion of chromatin requires a matched control experiment in order to determine nucleosome positions...
- A novel yeast silencer. the 2mu origin of Saccharomyces cerevisiae has HST3-, MIG1- and SIR-dependent silencing activityArnold Grünweller
Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany
Genetics 162:59-71. 2002..Also, Hst3 regulated the repression of the flipase gene, although this was likely an indirect effect of HST3 on FLP1 expression...
- A role for the Saccharomyces cerevisiae RENT complex protein Net1 in HMR silencingDaniela Kasulke
Max-Planck-Institute for Molecular Genetics, 14195 Berlin, Germany
Genetics 161:1411-23. 2002..In contrast, our data suggested that net1-1 acted indirectly in HMR silencing by releasing Sir2 from the nucleolus, thus shifting the internal competition for Sir2 from the silenced loci toward HMR...