Wei Chen

Summary

Affiliation: Max Planck Institute for Molecular Genetics
Country: Germany

Publications

  1. pmc Estimating accuracy of RNA-Seq and microarrays with proteomics
    Xing Fu
    Key Lab of Systems Biology, Shanghai Institutes for Biological Sciences, China Academy of Sciences, Shanghai, 200031, PR China
    BMC Genomics 10:161. 2009
  2. pmc Deciphering the porcine intestinal microRNA transcriptome
    Soroush Sharbati
    Freie Universitat Berlin, Institute of Veterinary Biochemistry, Oertzenweg 19b, 14163 Berlin, Germany
    BMC Genomics 11:275. 2010
  3. pmc Mapping translocation breakpoints by next-generation sequencing
    Wei Chen
    Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany
    Genome Res 18:1143-9. 2008
  4. pmc CGHPRO -- a comprehensive data analysis tool for array CGH
    Wei Chen
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
    BMC Bioinformatics 6:85. 2005
  5. ncbi request reprint Characterization of interstitial Xp duplications in two families by tiling path array CGH
    Andreas Tzschach
    Max Planck Institute for Molecular Genetics, Berlin, Germany
    Am J Med Genet A 146:197-203. 2008
  6. ncbi request reprint Characterization of a 5.3 Mb deletion in 15q14 by comparative genomic hybridization using a whole genome "tiling path" BAC array in a girl with heart defect, cleft palate, and developmental delay
    Fikret Erdogan
    Max Planck Institute for Molecular Genetics, Berlin, Germany
    Am J Med Genet A 143:172-8. 2007
  7. pmc Breakpoint analysis of balanced chromosome rearrangements by next-generation paired-end sequencing
    Wei Chen
    Max Planck Institute for Molecular Genetics, Berlin, Germany
    Eur J Hum Genet 18:539-43. 2010
  8. ncbi request reprint Array CGH identifies reciprocal 16p13.1 duplications and deletions that predispose to autism and/or mental retardation
    Reinhard Ullmann
    Max Planck Institute for Molecular Genetics, Berlin, Germany
    Hum Mutat 28:674-82. 2007
  9. pmc Hybridisation-based resequencing of 17 X-linked intellectual disability genes in 135 patients reveals novel mutations in ATRX, SLC6A8 and PQBP1
    Lars R Jensen
    Department of Human Molecular Genetics, Max Planck Institute for Molecular Genetics, Berlin, Germany
    Eur J Hum Genet 19:717-20. 2011
  10. pmc ST3GAL3 mutations impair the development of higher cognitive functions
    Hao Hu
    Department for Human Molecular Genetics, Max Planck Institute for Molecular Genetics, Berlin, Germany
    Am J Hum Genet 89:407-14. 2011

Detail Information

Publications68

  1. pmc Estimating accuracy of RNA-Seq and microarrays with proteomics
    Xing Fu
    Key Lab of Systems Biology, Shanghai Institutes for Biological Sciences, China Academy of Sciences, Shanghai, 200031, PR China
    BMC Genomics 10:161. 2009
    ..At present, high throughput sequencing is emerging as an alternative methodology for transcriptome studies. Although free of many limitations imposed by microarray design, its potential to estimate absolute transcript levels is unknown...
  2. pmc Deciphering the porcine intestinal microRNA transcriptome
    Soroush Sharbati
    Freie Universitat Berlin, Institute of Veterinary Biochemistry, Oertzenweg 19b, 14163 Berlin, Germany
    BMC Genomics 11:275. 2010
    ..g. intestinal development or disease. Recent studies indicate that miRNAs are key regulators of intestinal development and their aberrant expression leads to intestinal malignancy...
  3. pmc Mapping translocation breakpoints by next-generation sequencing
    Wei Chen
    Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany
    Genome Res 18:1143-9. 2008
    ..Its implementation will greatly facilitate large-scale breakpoint mapping and gene finding in patients with disease-associated balanced translocations...
  4. pmc CGHPRO -- a comprehensive data analysis tool for array CGH
    Wei Chen
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
    BMC Bioinformatics 6:85. 2005
    ....
  5. ncbi request reprint Characterization of interstitial Xp duplications in two families by tiling path array CGH
    Andreas Tzschach
    Max Planck Institute for Molecular Genetics, Berlin, Germany
    Am J Med Genet A 146:197-203. 2008
    ..These comprise known mental retardation genes such as MAOA, NDP, TM4SF2, NDP, RSK2, and CDKL5. Duplication of MAOA will be discussed as a possible cause of obesity...
  6. ncbi request reprint Characterization of a 5.3 Mb deletion in 15q14 by comparative genomic hybridization using a whole genome "tiling path" BAC array in a girl with heart defect, cleft palate, and developmental delay
    Fikret Erdogan
    Max Planck Institute for Molecular Genetics, Berlin, Germany
    Am J Med Genet A 143:172-8. 2007
    ....
  7. pmc Breakpoint analysis of balanced chromosome rearrangements by next-generation paired-end sequencing
    Wei Chen
    Max Planck Institute for Molecular Genetics, Berlin, Germany
    Eur J Hum Genet 18:539-43. 2010
    ..Our results show the feasibility of paired-end sequencing of systematic breakpoint mapping and gene finding in patients with disease-associated chromosome rearrangements...
  8. ncbi request reprint Array CGH identifies reciprocal 16p13.1 duplications and deletions that predispose to autism and/or mental retardation
    Reinhard Ullmann
    Max Planck Institute for Molecular Genetics, Berlin, Germany
    Hum Mutat 28:674-82. 2007
    ..Thus we conclude that these aberrations represent recurrent genomic imbalances which predispose to autism and/or MR...
  9. pmc Hybridisation-based resequencing of 17 X-linked intellectual disability genes in 135 patients reveals novel mutations in ATRX, SLC6A8 and PQBP1
    Lars R Jensen
    Department of Human Molecular Genetics, Max Planck Institute for Molecular Genetics, Berlin, Germany
    Eur J Hum Genet 19:717-20. 2011
    ..For four mutations affecting ATRX (p.1761M>T), PQBP1 (p.155R>X) and SLC6A8 (p.390P>L and p.477S>L), we provide evidence for a functional involvement of these changes in the aetiology of intellectual disability...
  10. pmc ST3GAL3 mutations impair the development of higher cognitive functions
    Hao Hu
    Department for Human Molecular Genetics, Max Planck Institute for Molecular Genetics, Berlin, Germany
    Am J Hum Genet 89:407-14. 2011
    ..Our data provide conclusive evidence that glycotopes formed by ST3Gal-III are prerequisite for attaining and/or maintaining higher cognitive functions...
  11. ncbi request reprint Mutation screening of brain-expressed X-chromosomal miRNA genes in 464 patients with nonsyndromic X-linked mental retardation
    Wei Chen
    Max Planck Institute for Molecular Genetics, Berlin, Germany
    Eur J Hum Genet 15:375-8. 2007
    ..All the observed changes appear to be functionally neutral which, taken together with the rarity of detected nucleotide changes in miRNA genes, may reflect strong selection and thus underline the functional importance of miRNAs...
  12. pmc Retargeting transposon insertions by the adeno-associated virus Rep protein
    Ismahen Ammar
    Max Delbruck Center for Molecular Medicine, 13125 Berlin, Germany
    Nucleic Acids Res 40:6693-712. 2012
    ..This study provides a comparative insight into target site selection properties of transposons, as well as proof-of-principle for targeted chromosomal transposition by composite protein-protein and protein-DNA interactions...
  13. ncbi request reprint A novel X-linked recessive mental retardation syndrome comprising macrocephaly and ciliary dysfunction is allelic to oral-facial-digital type I syndrome
    Bartlomiej Budny
    Max Planck Institute for Molecular Genetics, Ihnestr 73, 14195, Berlin, Germany
    Hum Genet 120:171-8. 2006
    ..This family broadens the phenotypic spectrum of OFD1 mutations in an unexpected way and sheds light on the complexity of the underlying disease mechanisms...
  14. ncbi request reprint MicroRNAs in brain function and disease
    Andreas Walter Kuss
    Department for Human Molecular Genetics, Max Planck Institute for Molecular Genetics, Ihnestr 73, D 14195, Berlin, Germany
    Curr Neurol Neurosci Rep 8:190-7. 2008
    ..We also discuss the implications of these findings with respect to the involvement of miRNAs in the etiopathology of brain disorders and pinpoint the emerging therapeutic potential of miRNAs for the treatment of human diseases...
  15. ncbi request reprint Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia
    George Kirov
    Department of Psychological Medicine, Cardiff University, Henry Wellcome Building, Heath Park, Cardiff CF14 4XN, UK
    Hum Mol Genet 17:458-65. 2008
    ..Both genes have been affected by CNVs in patients with autism and mental retardation, but neither has been previously implicated in SZ...
  16. ncbi request reprint Homozygosity mapping in consanguineous families reveals extreme heterogeneity of non-syndromic autosomal recessive mental retardation and identifies 8 novel gene loci
    Hossein Najmabadi
    Genetics Research Centre, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
    Hum Genet 121:43-8. 2007
    ..Our data suggest that in the Iranian population NS-ARMR is very heterogeneous, and they argue against the existence of frequent gene defects that account for more than a few percent of the cases...
  17. pmc Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis
    Damini Jawaheer
    Center for Genomics and Human Genetics, North Shore Long Island Jewish Research Institute, Manhasset, NY, 11030, USA
    Am J Hum Genet 71:585-94. 2002
    ....
  18. ncbi request reprint ConCept: de novo design of synthetic receptors for targeted ligands
    Wei Chen
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    J Chem Inf Model 47:425-34. 2007
    ..All three modes of operation are illustrated here through the design of novel adenine receptors...
  19. ncbi request reprint Autosomal genome scan for loci linked to blood pressure levels and trends since childhood: the Bogalusa Heart Study
    Wei Chen
    Tulane Center for Cardiovascular Health and Department of Epidemiology, Tulane School of Public Health and Tropical Medicine, New Orleans, LA, USA
    Hypertension 45:954-9. 2005
    ..Linkage evidence found in this community-based study indicates that regions on these chromosomes harbor genetic loci that affect the propensity for development of hypertension from childhood...
  20. pmc Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data
    Kerby Shedden
    Department of Statistics, University of Michigan, Ann Arbor, Michigan, USA
    BMC Bioinformatics 6:26. 2005
    ....
  21. ncbi request reprint A draft sequence of the rice genome (Oryza sativa L. ssp. indica)
    Jun Yu
    Beijing Genomics Institute Center of Genomics and Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China
    Science 296:79-92. 2002
    ..4% of predicted rice genes had a homolog in A. thaliana. The large proportion of rice genes with no recognizable homologs is due to a gradient in the GC content of rice coding sequences...
  22. doi request reprint Discovering microRNAs from deep sequencing data using miRDeep
    Marc R Friedländer
    Max Delbruck Centrum fur Molekulare Medizin, Robert Rossle Strasse 10, D 13125 Berlin Buch, Germany
    Nat Biotechnol 26:407-15. 2008
    ..miRDeep reports altogether approximately 230 previously unannotated miRNAs, of which four novel C. elegans miRNAs are validated by northern blot analysis...
  23. doi request reprint Novel breast cancer biomarkers identified by integrative proteomic and gene expression mapping
    Keli Ou
    Agenica Research Pte Ltd, National Cancer Centre of Singarope, and Genome Institute of Singapore, 11 Hospital Drive, Singapore 169610
    J Proteome Res 7:1518-28. 2008
    ..Our study thus illustrates how the systematic integration of proteomic and transcriptomic data from both cell line and primary tissue samples can prove advantageous for accelerating cancer biomarker discovery...
  24. ncbi request reprint Gene expression profile of salivary adenoid cystic carcinoma associated with perineural invasion
    Wei Chen
    Department of Oral and Maxillofacial Surgery, School of Stomatology, Fourth Military Medical University, Shaanxi, P R China
    Tohoku J Exp Med 212:319-34. 2007
    ..These identified novel genes deserve further investigations to elucidate their clinicopathological significance...
  25. doi request reprint Mapping and quantitative trait loci analysis of verticillium wilt resistance genes in cotton
    Hong Mei Wang
    National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China
    J Integr Plant Biol 50:174-82. 2008
    ..QTLs explaining large phenotypic variation were identified in this study, which may be quite useful in cotton anti-disease breeding...
  26. ncbi request reprint Towards map-based cloning: fine mapping of a recessive genic male-sterile gene (BnMs2) in Brassica napus L. and syntenic region identification based on the Arabidopsis thaliana genome sequences
    Shaolin Lei
    National Key Laboratory of Crop Genetic Improvement, National Sub center of Rapeseed Improvement in Wuhan, Huazhong Agricultural University, Wuhan 430070, China
    Theor Appl Genet 115:643-51. 2007
    ..Molecular markers developed from these investigations will facilitate the marker-assisted selection (MAS) of RGMS lines, and the fine map and syntenic region identified will greatly hasten the process of positional cloning of BnMs2 gene...
  27. ncbi request reprint Association of EcoRI polymorphism of the metastasis-suppressor gene NME1 with susceptibility to and severity of non-small cell lung cancer
    Yih Shou Hsieh
    Institute of Biochemistry and Biotechnology, Chung Shan Medical University, No 110, Sec 1, Chien Kuo N Road, Taichung 402, Taiwan
    Lung Cancer 58:191-5. 2007
    ..With this allelic association study, we aimed to investigate the impact of polymorphisms of the NME1 gene on the susceptibility to and severity of non-small cell lung cancer (NSCLC)...
  28. ncbi request reprint A genome-wide association study of global gene expression
    Anna L Dixon
    National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK
    Nat Genet 39:1202-7. 2007
    ..We have created a downloadable database to facilitate use of our findings in the mapping of complex disease loci...
  29. pmc A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration
    Atsuhiro Kanda
    Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI 48105, USA
    Proc Natl Acad Sci U S A 104:16227-32. 2007
    ..We propose that rs10490924 represents a major susceptibility variant for AMD at 10q26. A likely biological mechanism is that the A69S change in the LOC387715/ARMS2 protein affects its presumptive function in mitochondria...
  30. ncbi request reprint Analysis of polymorphisms in the 3' untranslated region of the LDL receptor gene and their effect on plasma cholesterol levels and drug response
    Wei Chen
    VA Palo Alto Health Care System, Palo Alto, CA 94304, USA
    Int J Mol Med 21:345-53. 2008
    ....
  31. ncbi request reprint Genetic susceptibility to age-related macular degeneration: a paradigm for dissecting complex disease traits
    Anand Swaroop
    Department of Ophthalmology, University of Michigan, Ann Arbor, MI 48105, USA
    Hum Mol Genet 16:R174-82. 2007
    ....
  32. doi request reprint Effect of parental coronary artery disease on adverse effects of the metabolic syndrome and aging on carotid artery intima-media thickness (from the Bogalusa Heart Study)
    Wei Chen
    Tulane Center for Cardiovascular Health and Department of Epidemiology, Tulane University Health Sciences Center, New Orleans, Louisiana, USA
    Am J Cardiol 102:180-3. 2008
    ..These findings reinforce the value of using family history of CAD in risk assessment algorithm...
  33. ncbi request reprint Measuring stipple aesthetics in hand-drawn and computer-generated images
    Ross Maciejewski
    Purdue University, USA
    IEEE Comput Graph Appl 28:62-74. 2008
    ..To explore and explain these differences, the authors compare texture stippling in hand-drawn and computer-generated illustrations, using image-processing analysis techniques...
  34. ncbi request reprint Real-time detection of respiratory activity using an inertial measurement unit
    Henrik Gollee
    Centre for Rehabilitation Engineering, University of Glasgow, Glasgow, G12 8QQ, Scotland, UK
    Conf Proc IEEE Eng Med Biol Soc 2007:2230-3. 2007
    ..This novel method could therefore be suitable for use in automatic abdominal stimulation systems to support respiratory activity in tetraplegia where the stimulation is applied depending on the respirator activity of the subject...
  35. pmc Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis
    Timothy A Chan
    Cancer Biology Program, The Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States of America
    PLoS Med 5:e114. 2008
    ..We hypothesize that key tumor suppressor genes in cancer may be subject to mutation or hypermethylation...
  36. doi request reprint Relation of childhood risk factors to left ventricular hypertrophy (eccentric or concentric) in relatively young adulthood (from the Bogalusa Heart Study)
    Ahmet Toprak
    Tulane Center for Cardiovascular Health, New Orleans, Louisiana, USA
    Am J Cardiol 101:1621-5. 2008
    ..In conclusion, in this community-based study of young adults, eccentric LV hypertrophy was more frequent and obesity since childhood was the only consistent and significant determinant of this type of adverse cardiac remodeling...
  37. ncbi request reprint SAGE library screening reveals ILT7 as a specific plasmacytoid dendritic cell marker that regulates type I IFN production
    Minkwon Cho
    Department of Immunobiology, Ginkgo Biomedical Research Institute, Tokyo, Japan
    Int Immunol 20:155-64. 2008
    ..We conclude that ILT7 is a key regulator of human pDC function...
  38. doi request reprint Using Chou's pseudo amino acid composition to predict protein quaternary structure: a sequence-segmented PseAAC approach
    Shao Wu Zhang
    College of Automation, Northwestern Polytechnical University, 710072, Xi an, China
    Amino Acids 35:591-8. 2008
    ..The overall jackknife success rates thus obtained were 88.2-89.1%, indicating that the new approach is quite promising for predicting protein quaternary structure...
  39. doi request reprint A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus
    Swapan K Nath
    Genetic Epidemiology Unit, Oklahoma Medical Research Foundation, 825 NE 13th St, Oklahoma City, Oklahoma 73104, USA
    Nat Genet 40:152-4. 2008
    ..0002 and 0.003; overall meta-analysis P = 6.9 x 10(-22)). The genetic association between ITGAM and SLE implicates the alpha(M)beta2-integrin adhesion pathway in disease development...
  40. ncbi request reprint Identification of 18S ribosomal DNA genotype of Acanthamoeba from patients with keratitis in North China
    Yan Zhang
    Beijing Tongren Hospital, Beijing Institute of Ophthalmology, Capital University of Medical Science, Beijing, China
    Invest Ophthalmol Vis Sci 45:1904-7. 2004
    ..To identify the genotype of 18S ribosomal RNA gene (18S rDNA, Rns) of the Acanthamoeba strains isolated from patients with keratitis in northern China...
  41. ncbi request reprint Analysis of similarity/dissimilarity of long DNA sequences based on three 2DD-curves
    Yusen Zhang
    Department of Applied Mathematics, Shandong University at Weihai, Weihai 264209, China
    Comb Chem High Throughput Screen 10:231-7. 2007
    ..In this paper, we present a new 2D graphical representation of DNA sequences without degeneracy. Furthermore, we propose two methods for the visualization and analysis of long DNA sequences...
  42. ncbi request reprint Agents with selective estrogen receptor (ER) modulator activity induce apoptosis in vitro and in vivo in ER-negative glioma cells
    Ai Min Hui
    Neuro Oncology Branch, National Cancer Institute, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, and Celgene, San Diego, California, USA
    Cancer Res 64:9115-23. 2004
    ....
  43. ncbi request reprint Gender-specific influence of NO synthase gene on blood pressure since childhood: the Bogalusa Heart Study
    Wei Chen
    Tulane Center for Cardiovascular Health and Department of Epidemiology, Tulane University Health Sciences Center, New Orleans, LA 70112, USA
    Hypertension 44:668-73. 2004
    ..In conclusion, the endothelial NO synthase gene influences the long-term burden and trend of blood pressure since childhood in females and may contribute to their predisposition to hypertension...
  44. pmc Calculation of cyclodextrin binding affinities: energy, entropy, and implications for drug design
    Wei Chen
    Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, Maryland 20850, USA
    Biophys J 87:3035-49. 2004
    ..In close analogy with the common experimental observation of entropy-enthalpy compensation, the computed entropy changes show a near-linear relationship with the changes in mean potential plus solvation energy...
  45. ncbi request reprint The beta(2)-adrenergic receptor Arg16-gly polymorphism and interactions involving beta(2)- and beta(3)-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: the Bogalusa Heart Study
    D Michael Hallman
    Human Genetics Center, University of Texas Health Sciences Center at Houston, Houston, TX 77225, USA
    Metabolism 53:1184-91. 2004
    ....
  46. ncbi request reprint Monitoring of gene expression profiles and isolation of candidate genes involved in pollination and fertilization in rice ( Oryza sativa L.) with a 10K cDNA microarray
    Lefu Lan
    Institute of Genetics and Development Biology, Chinese Academy of Science and National Center for Plant Gene Research, Beijing 100080, China
    Plant Mol Biol 54:471-87. 2004
    ..In addition, the genes that differentially expressed during pollination represent candidate genes for dissecting molecular mechanism of this important biological process in rice...
  47. ncbi request reprint Nitric oxide synthase gene polymorphism (G894T) influences arterial stiffness in adults: The Bogalusa Heart Study
    Wei Chen
    Tulane Center for Cardiovascular Health, Tulane University Health Sciences Center, New Orleans, Louisiana 70112, USA
    Am J Hypertens 17:553-9. 2004
    ..046) and YEM (P =.035). These results suggest that the allelic variation (G894T) of the eNOS gene or a locus closely linked to it is associated with lower arterial wall stiffness, adjusting for BP levels, in young adults...
  48. ncbi request reprint Development of gene microarray in screening differently expressed genes in keloid and normal-control skin
    Wei Chen
    Department of Wound Healing, 304th Hospital, Beijing 100037, China
    Chin Med J (Engl) 117:877-81. 2004
    ..Keloid is an intricate lesion that is probably regulated by many genes. In this study, the authors used the technique of complementary DNA (cDNA) microarray to analyse abnormal gene expression in keloids and normal control skins...
  49. pmc The Chinese Visible Human (CVH) datasets incorporate technical and imaging advances on earlier digital humans
    Shao xiang Zhang
    Department of Anatomy, College of Medicine, Third Military Medical University, Chongqing 400038, China
    J Anat 204:165-73. 2004
    ..chinesevisiblehuman.com. (The male is 90.65 Gb and female 131.04 Gb). MPEG videos of direct records of real-time volume rendering are at: http://www.cse.cuhk.edu.hk/~crc..
  50. ncbi request reprint Interactive effects of MC1R and OCA2 on melanoma risk phenotypes
    David L Duffy
    Queensland Insititute of Medical Research, Brisbane, Australia
    Hum Mol Genet 13:447-61. 2004
    ..Amongst individuals with a R/R genotype (but not R/r), those who also had brown eyes had a mole count twice that of those with blue eyes. This suggests that other OCA2 polymorphisms influence mole count and remain to be described...
  51. ncbi request reprint A human CR1-like transcript containing sequence for a binding protein for iC4 is expressed in hematopoietic and fetal lymphoid tissue
    Christine M Logar
    Division of Nephrology, Department of Internal Medicine, The Ohio State University, N210 Means Hall, 1654 Upham Dr, Columbus, OH 43210, USA
    Mol Immunol 40:831-40. 2004
    ..Thus, expression of the CR1L transcript appears to be limited to hematopoietic and fetal lymphoid tissue...
  52. ncbi request reprint Molecular cloning, developmental expression, promoter analysis and functional characterization of the mouse CNBP gene
    Ken Shimizu
    Department of Cytokine Biology, The Forsyth Institute, Boston, MA 02115, USA
    Gene 307:51-62. 2003
    ..Our finds suggest that CNBP may play an important role in cell proliferation and tissue patterning during anterior-posterior axis, craniofacial and limb development by targeting c-Myc...
  53. ncbi request reprint Sequence and analysis of rice chromosome 4
    Qi Feng
    National Center for Gene Research, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 500 Caobao Road, Shanghai 200233, China
    Nature 420:316-20. 2002
    ..By contrast, there is little conservation in gene order between rice and Arabidopsis...
  54. ncbi request reprint Impact of multiple cardiovascular risk factors on femoral artery intima-media thickness in asymptomatic young adults (the Bogalusa Heart Study)
    Timir K Paul
    Tulane Center for Cardiovascular Health, Tulane University Health Sciences Center, New Orleans, Louisiana, USA
    Am J Cardiol 95:469-73. 2005
    ..Further, ultrasonography of the femoral artery in conjunction with multiple risk factor profiling can be helpful in risk stratification...
  55. ncbi request reprint [Oligonucleotide microarrays in the screening of differentially expressed genes in skin of rat fetus in early and late pregnancy ]
    Wei Chen
    State Key Laborary of Trauma Repair, No 304 Hospital of China PLA, Beijing 100037, China
    Zhonghua Yi Xue Za Zhi 85:487-9. 2005
  56. pmc Degenerated primer design to amplify the heavy chain variable region from immunoglobulin cDNA
    Ying Wang
    Center for Laboratory Medicine, First Teaching Hospital of Medical School, Xi an Jiaotong University, Xi an 710061, China
    BMC Bioinformatics 7:S9. 2006
    ..Using conventional protocols, the heavy-chain variable region genes often are not amplified successfully from the hybridoma cell lines...
  57. ncbi request reprint [The clinical significance of expression and amplification of FGF3 in bladder transitional cell carcinoma]
    Yong hai Zhang
    Department of Urology, Shantou Central Hospital, Guangdong 515031, China
    Zhonghua Yi Xue Za Zhi 86:2556-9. 2006
    ..To investigate the amplification and expression of FGF3 in bladder transitional cell carcinoma (BTCC) and its clinical significance...
  58. ncbi request reprint Polymorphisms of p53 and p21 genes in chronic obstructive pulmonary disease
    Yao Ling Lee
    School of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan
    J Lab Clin Med 147:228-33. 2006
    ..To investigate the involvement of genetic polymorphisms of p53 and p21 in the pathogenesis of COPD, the authors performed a case-control study involving 206 subjects with COPD and 210 healthy smokers as control subjects...
  59. ncbi request reprint Targets of genome copy number reduction in primary breast cancers identified by integrative genomics
    Wei Chen
    Agenica Research, Singapore 169610, Republic of Singapore
    Genes Chromosomes Cancer 46:288-301. 2007
    ..This article contains Supplementary Material available at http://www.interscience.wiley.com/jpages/1045-2257/suppmat...
  60. ncbi request reprint Race (black-white) and gender divergences in the relationship of childhood cardiovascular risk factors to carotid artery intima-media thickness in adulthood: the Bogalusa Heart Study
    Shengxu Li
    Tulane Center for Cardiovascular Health, New Orleans, LA 70112, USA
    Atherosclerosis 194:421-5. 2007
    ..In conclusion, the predictability of childhood CV risk factors for increased carotid IMT in adulthood varies by race and gender. The prevention implications of these findings need further investigation...
  61. ncbi request reprint Adiponectin and its correlates of cardiovascular risk in young adults: the Bogalusa Heart Study
    Dharmendrakumar A Patel
    Tulane Center for Cardiovascular Health, Tulane University Health Science Center, New Orleans, LA 70112, USA
    Metabolism 55:1551-7. 2006
    ....
  62. ncbi request reprint A computer-aided method to expedite the evaluation of prognosis for childhood acute lymphoblastic leukemia
    Xingwei Wang
    Center for Bioengineering and School of Electrical and Computer Engineering, University of Oklahoma, Oklahoma, USA
    Technol Cancer Res Treat 5:429-36. 2006
    ..The results demonstrated the feasibility or potential of using a computerized method to replace the tedious and the reader-dependent diagnostic methods commonly used in genetic laboratories to date...
  63. ncbi request reprint Invariants of DNA sequences based on 2DD-curves
    Yusen Zhang
    School of Information and Engineering, Shandong University at Weihai, Weihai 264209, China
    J Theor Biol 242:382-8. 2006
    ..We can use it as an alternative invariant to characterize the DNA sequence. The utility of the new parameter is illustrated on the DNA sequences of 11 species...
  64. ncbi request reprint [Screening and identification of heterogeneous phenotype-associated genes in human bladder cancer]
    Yu cong Yang
    Center of Laboratory Medicine, First Affiliated Hospital, Medical School of Xi an Jiaotong University, Xi an 710061, China
    Nan Fang Yi Ke Da Xue Xue Bao 26:270-4. 2006
    ..To screen and identify heterogeneous phenotype-associated genes of human bladder transitional cell carcinoma...
  65. ncbi request reprint Increased subclinical atherosclerosis in young adults with metabolic syndrome: the Bogalusa Heart Study
    Wendy S Tzou
    Atherosclerosis Imaging Research Program, Section of Cardiovascular Medicine, University Medical School, Madison, Wisconsin 53792, USA
    J Am Coll Cardiol 46:457-63. 2005
    ..The purpose of this study was to investigate the association of metabolic syndrome (MetS) with subclinical atherosclerosis, determined by ultrasound carotid intima-media thickness (CIMT) measurements, in young adults...
  66. pmc Preoperative antibiotics and mortality in the elderly
    Jeffrey H Silber
    Center for Outcomes Research, Children s Hospital of Philadelphia, Philadelphia, PA, USA
    Ann Surg 242:107-14. 2005
    ..The objective of this study was to determine whether preoperative antibiotics are associated with a reduced risk of death...
  67. ncbi request reprint Identification and preliminary characterization of cell-wall-anchored proteins of Staphylococcus epidermidis
    M Gabriela Bowden
    Center for Extracellular Matrix Biology, Institute of Biosciences and Technology, Texas A and M University Health Science Center, Houston, TX 77030 3303, USA
    Microbiology 151:1453-64. 2005
    ..Western blot analyses of early-logarithmic and late-stationary in vitro cultures suggest that different regulatory mechanisms control the expression of the Ses proteins...
  68. ncbi request reprint A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
    Hiromu Suzuki
    The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins University School of Medicine, 1650 Orleans Street, Baltimore, Maryland 21231, USA
    Nat Genet 31:141-9. 2002
    ....