Research Topics
| Federico D BrownSummaryAffiliation: Max Planck Institute for Biological Cybernetics Country: Germany Publications
| Collaborators |
Detail Information
Publications
Whole body regeneration in a colonial ascidian, Botrylloides violaceusFederico D Brown
Biology Department, Center for Developmental Biology, and Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington, USA
J Exp Zool B Mol Dev Evol 312:885-900. 2009..We propose that multiple stem cell types are circulating within B. violaceus and that they undergo proliferation in the peripheral vasculature before differentiating into epithelial tissues for all three germ layers during WBR...
Evolution and development of budding by stem cells: ascidian coloniality as a case studyFederico D Brown
Biology Department, University of Washington, Seattle, 98195, USA
Dev Biol 369:151-62. 2012..We review hypotheses for changes in stem cell lineages in colonial species, describe what the current data suggest about the evolution of budding, and discuss where we believe further studies will be most fruitful...
Early lineage specification of long-lived germline precursors in the colonial ascidian Botryllus schlosseriFederico D Brown
Biology Department, Center for Developmental Biology, and Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98195, USA
Development 136:3485-94. 2009..Transient vasa knockdown did not have obvious effects on germline or somatic development in adult colonies, although it did result in a profound heterochrony, suggesting that vasa might play a homeostatic role in asexual development...
Vasa expression in a colonial ascidian, Botrylloides violaceusFederico D Brown
Biology Department, Center for Developmental Biology, and Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98195, USA
Evol Dev 9:165-77. 2007..We propose that expression of vasa in cells other than gonadal germ cells of zooids in a colonial ascidian may serve as a source of germ-line stem cells in the colony...
Man is but a worm: chordate originsFederico D Brown
Biology Department and Center for Developmental Biology, University of Washington, Seattle, Washington 98195, USA
Genesis 46:605-13. 2008..We conclude that "Man is but a worm...," that our chordate ancestors were worm-like deposit and/or filter feeders with pharyngeal slits, and an anterior tripartite unsegmented neurosensory region...
