E B Binder

Summary

Affiliation: Max Planck Institute of Psychiatry
Country: Germany

Publications

  1. pmc Peripheral blood gene expression: it all boils down to the RNA collection tubes
    Andreas Menke
    Max Planck Institute of Psychiatry, Kraepelinstr, 10, D 80804 Munich, Germany
    BMC Res Notes 5:1. 2012
  2. pmc Gene expression studies in major depression
    Divya Mehta
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Curr Psychiatry Rep 12:135-44. 2010
  3. doi request reprint The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Munich, Germany
    Psychoneuroendocrinology 34:S186-95. 2009
  4. ncbi request reprint Effects of neurotensin receptor antagonism on latent inhibition in Sprague-Dawley rats
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Psychopharmacology (Berl) 161:288-95. 2002
  5. pmc A serotonin transporter gene polymorphism predicts peripartum depressive symptoms in an at-risk psychiatric cohort
    Elisabeth B Binder
    Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, USA
    J Psychiatr Res 44:640-6. 2010
  6. doi request reprint HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients
    E B Binder
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, D80804 Munich, Germany
    Psychoneuroendocrinology 34:99-109. 2009
  7. ncbi request reprint Pharmacological and nonpharmacological factors influencing hypothalamic-pituitary-adrenocortical axis reactivity in acutely depressed psychiatric in-patients, measured by the Dex-CRH test
    H E Künzel
    Department of Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany
    Neuropsychopharmacology 28:2169-78. 2003
  8. ncbi request reprint Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Nat Genet 36:1319-25. 2004
  9. ncbi request reprint Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating
    E B Binder
    Max Planck Institute for Psychiatry, 80804 Munich, Germany
    J Neurosci 21:601-8. 2001
  10. ncbi request reprint P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder
    Susanne Lucae
    The Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Hum Mol Genet 15:2438-45. 2006

Detail Information

Publications57

  1. pmc Peripheral blood gene expression: it all boils down to the RNA collection tubes
    Andreas Menke
    Max Planck Institute of Psychiatry, Kraepelinstr, 10, D 80804 Munich, Germany
    BMC Res Notes 5:1. 2012
    ..abstract:..
  2. pmc Gene expression studies in major depression
    Divya Mehta
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Curr Psychiatry Rep 12:135-44. 2010
    ..Finally, we discuss possible new strategies for the gene expression studies in MD that circumvent some of the addressed issues...
  3. doi request reprint The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Munich, Germany
    Psychoneuroendocrinology 34:S186-95. 2009
    ..In addition, they are also associated with faster response to antidepressant treatment. FKBP5 might thus be an interesting therapeutic target for the prevention and treatment of stress-related psychiatric disorders...
  4. ncbi request reprint Effects of neurotensin receptor antagonism on latent inhibition in Sprague-Dawley rats
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Psychopharmacology (Berl) 161:288-95. 2002
    ..A critical test of this hypothesis would be to determine if NT is involved in the expression of latent inhibition (LI), a psychophysiological and pharmacological model of schizophrenia...
  5. pmc A serotonin transporter gene polymorphism predicts peripartum depressive symptoms in an at-risk psychiatric cohort
    Elisabeth B Binder
    Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, USA
    J Psychiatr Res 44:640-6. 2010
    ..The aim of this study was to investigate associations of the serotonin-transporter linked polymorphic region (5-HTTLPR) genotype with peripartum MDD in an at-risk population...
  6. doi request reprint HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients
    E B Binder
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, D80804 Munich, Germany
    Psychoneuroendocrinology 34:99-109. 2009
    ..In male patients, a single measure of HPA-axis dysregulation at admission may serve as a predictor of response to antidepressant treatment in addition to the previously reported repeated measure of the Dex-CRH test...
  7. ncbi request reprint Pharmacological and nonpharmacological factors influencing hypothalamic-pituitary-adrenocortical axis reactivity in acutely depressed psychiatric in-patients, measured by the Dex-CRH test
    H E Künzel
    Department of Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany
    Neuropsychopharmacology 28:2169-78. 2003
    ..Finally, more severe vegetative symptoms are associated with an enhanced HPA-axis activity...
  8. ncbi request reprint Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Nat Genet 36:1319-25. 2004
    ..These findings support a central role of genes regulating the HPA axis in the causality of depression and the mechanism of action of antidepressant drugs...
  9. ncbi request reprint Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating
    E B Binder
    Max Planck Institute for Psychiatry, 80804 Munich, Germany
    J Neurosci 21:601-8. 2001
    ..These novel findings, together with previous observations, suggest that neurotensin receptor agonists may represent a novel class of antipsychotic drugs...
  10. ncbi request reprint P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder
    Susanne Lucae
    The Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Hum Mol Genet 15:2438-45. 2006
    ..This polymorphism results in an amino acid exchange in the C-terminal cytosolic domain of the P2RX7 channel protein, suggesting that the observed P2RX7 polymorphism might play a causal role in the development of depression...
  11. doi request reprint Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression
    A Menke
    Department of Molecular Genetics of Affective Disorders, Max Planck Institute of Psychiatry, D 80804 Munich, Germany
    Genes Brain Behav 12:289-96. 2013
    ..This finding suggests that endocrine alterations in depressed patients are determined by genetic variants and may allow identification of specific subgroups...
  12. doi request reprint Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression
    S Kloiber
    Max Planck Institute of Psychiatry, Munich, Germany
    Mol Psychiatry 15:736-47. 2010
    ..Identifying depressed patients at high risk for MetS using genetic variants could have direct clinical impact on individualized disease management and prevention strategies...
  13. doi request reprint TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies
    A Erhardt
    Max Planck Institute of Psychiatry, Munchen, Germany
    Mol Psychiatry 16:647-63. 2011
    ..TMEM132D may thus be an important new candidate gene for PD as well as more generally for anxiety-related behavior...
  14. doi request reprint Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project
    Johannes M Hennings
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    J Psychiatr Res 43:215-29. 2009
    ..We demonstrated that this subgroup can be characterized by a set of demographic, clinical and neuroendocrine variables allowing to predict unfavorable outcome at an early stage of treatment...
  15. doi request reprint Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 Munich, Germany
    Arch Gen Psychiatry 67:369-79. 2010
    ..The corticotropin-releasing factor (CRF, or corticotropin-releasing hormone) and arginine vasopressin systems have been implicated in the pathophysiology of anxiety and depressive disorders and response to antidepressant treatment...
  16. doi request reprint A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
    Marcus Ising
    Max Planck Institute of Psychiatry, Munich 80804, Germany
    Arch Gen Psychiatry 66:966-75. 2009
    ..Genetic factors and clinical characteristics contribute to the failure of a favorable treatment outcome...
  17. pmc The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders
    C K Thoeringer
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    J Neural Transm 116:649-57. 2009
    ..These data indicate a high load of genetic variance within SLC6A1 on pathological anxiety and highlight GAT-1 as a promising target for treatment of anxiety disorders with panic symptoms...
  18. pmc Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults
    Elisabeth B Binder
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia 30329, USA
    JAMA 299:1291-305. 2008
    ..Both genetic and environmental factors are contributory, with child abuse providing significant risk liability...
  19. ncbi request reprint Hypothalamus-pituitary-adrenal system regulation and suicidal behavior in depression
    Andrea Pfennig
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 57:336-42. 2005
    ..So far data on the involvement of the HPA axis in the pathophysiology of suicidal behavior in depressed patients are controversial...
  20. ncbi request reprint Association of a Met88Val diazepam binding inhibitor (DBI) gene polymorphism and anxiety disorders with panic attacks
    Christoph K Thoeringer
    Max Planck Institute of Psychiatry, Munich 80804, Germany
    J Psychiatr Res 41:579-84. 2007
    ..43; 95% CI: 0.19-0.95). In conclusion, these results suggest a central role of DBI genetic variants in the susceptibility for the development of anxiety disorders that are characterized by the occurrence of panic attacks...
  21. ncbi request reprint Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism
    T C Baghai
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University of Munich, Munich, Germany
    Mol Psychiatry 11:1003-15. 2006
    ..We could show that SNP rs4291 influences ACE activity and HPA-axis hyperactivity and might therefore represent a common pathophysiologic link for unipolar depression and cardiovascular disease...
  22. ncbi request reprint Impaired divided attention predicts delayed response and risk to relapse in subjects with depressive disorders
    M Majer
    Max Planck Institute of Psychiatry, Munich, Germany
    Psychol Med 34:1453-63. 2004
    ..This study addresses the complex relationship between cognitive function and the course of depression...
  23. ncbi request reprint ABCB1 (MDR1)-type P-glycoproteins at the blood-brain barrier modulate the activity of the hypothalamic-pituitary-adrenocortical system: implications for affective disorder
    Marianne B Muller
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, 80804 Munich, Germany
    Neuropsychopharmacology 28:1991-9. 2003
    ....
  24. ncbi request reprint Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder
    Paul G Unschuld
    Max Planck Institute of Psychiatry, Munchen, Germany
    Am J Med Genet B Neuropsychiatr Genet 144:424-9. 2007
    ..These results further underline a possible important role of genetic variations within the system controlling serotonergic neurotransmission for the development and course of disease in PD...
  25. ncbi request reprint Regulation of the hypothalamic-pituitary-adrenocortical system in patients with panic disorder
    Angelika Erhardt
    Max Planck Institute of Psychiatry, Munich, Germany
    Neuropsychopharmacology 31:2515-22. 2006
    ..However, differences in the suppression effects and psychopathological correlation patterns between depressed and panic patients suggest different biological mechanisms of HPA system dysregulation in both disorders...
  26. pmc Convergent animal and human evidence suggests the activin/inhibin pathway to be involved in antidepressant response
    K Ganea
    Max Planck Institute of Psychiatry, Munich, Germany
    Transl Psychiatry 2:e177. 2012
    ..Further, our data suggest this pathway to be a target for more rapid-acting antidepressants in the future...
  27. ncbi request reprint Neurotensin and dopamine interactions
    E B Binder
    Laboratory of Neuropsychopharmacology, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
    Pharmacol Rev 53:453-86. 2001
    ..Last, because of the extensive literature on NT/DA interactions available in the rat, our discussion will be based primarily on studies using this species...
  28. doi request reprint Pharmacogenomics of antidepressant drugs
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Munich, Germany
    Pharmacol Ther 124:57-73. 2009
    ..Illustrated by examples from current candidate gene- and whole genome association studies, this manuscript critically discusses aspects of pharmacogenetic studies in antidepressant response related to study design and clinical relevance...
  29. doi request reprint Regulation of mRNA expression encoding chaperone and co-chaperone proteins of the glucocorticoid receptor in peripheral blood: association with depressive symptoms during pregnancy
    E R Katz
    Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, USA
    Psychol Med 42:943-56. 2012
    ..Major depressive disorder during pregnancy associates with potentially detrimental consequences for mother and child. The current study examined peripheral blood gene expression as a potential biomarker for prenatal depressive symptoms...
  30. pmc Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment
    Sonja Horstmann
    Max Planck Institute of Psychiatry, Munich, Germany
    Neuropsychopharmacology 35:727-40. 2010
    ....
  31. pmc Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response
    Paul G Unschuld
    Max Planck Institute of Psychiatry, Munchen, Germany
    Neuropsychopharmacology 35:1583-92. 2010
    ..The reported associations in independent samples of AD and MDD support an estrogen-dependent function of GAL in pathophysiology of anxiety and depression, affecting response to antidepressant treatment...
  32. doi request reprint Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders
    Paul G Unschuld
    Max Planck Institute of Psychiatry, Munchen, Germany
    Am J Med Genet B Neuropsychiatr Genet 150:1100-9. 2009
    ..However, data from expression studies imply that these polymorphisms could tag functional effects on the neighboring gene MYO3A, which is also expressed in the brain, including the cingulate cortex and the amygdala...
  33. doi request reprint Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus
    Mathias V Schmidt
    Research Group Neurobiology of Stress, Max Planck Institute of Psychiatry, 80804 Munich, Germany
    J Neurosci 30:16949-58. 2010
    ..Those individual differences can be predicted by the assessment of short-term memory, thereby opening up the possibility for a specific treatment by enhancing AMPA receptor function...
  34. pmc Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms
    Kerry J Ressler
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 954 Gatewood Drive, Atlanta, GA 30329, USA
    Am J Med Genet B Neuropsychiatr Genet 153:812-24. 2010
    ....
  35. pmc Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients
    Martin A Kohli
    Max Planck Institute of Psychiatry, Kraepelinstrasse 2 10, D 80804 Munich, Germany
    Arch Gen Psychiatry 67:348-59. 2010
    ..Especially in suicide victims, lower postmortem brain messenger RNA and protein levels of neurotrophins and their receptors have been reported...
  36. ncbi request reprint Successful antidepressant therapy restores the disturbed interplay between TNF-alpha system and HPA axis
    Hubertus Himmerich
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 60:882-8. 2006
    ....
  37. ncbi request reprint The combined dexamethasone/CRH test as a potential surrogate marker in depression
    Marcus Ising
    Max Planck Institute of Psychiatry, Kraepelinstr 10, D 80804 Munich, Germany
    Prog Neuropsychopharmacol Biol Psychiatry 29:1085-93. 2005
    ..Further systematic research is required and already ongoing to confirm the suitability of the combined dex/CRH test as a surrogate marker in depression...
  38. ncbi request reprint Pharmacogenomics and antidepressant drugs
    Elisabeth B Binder
    Max Planck Institute of Psychiatry, Munich, Germany
    Ann Med 38:82-94. 2006
    ..These studies mark the beginning of an emerging standard SNP profiling system that ultimately allows identifying the right drug for the right patient at the right time...
  39. ncbi request reprint Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression - a potential biomarker?
    Marcus Ising
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 62:47-54. 2007
    ..In the present study, we examined whether change in HPA system function during the first weeks of hospitalization predicts response to antidepressant treatment in major depression and thus constitutes a potential biomarker...
  40. ncbi request reprint Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders
    Angelika Erhardt
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, D 80804 München, Germany
    J Affect Disord 101:159-68. 2007
    ..This region contains two candidate genes for purinergic ligand-gated ion channels, P2RX7 and P2RX4, and one gene coding for calmodulin-dependent protein kinase kinase b (CaMKKb)...
  41. ncbi request reprint Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder
    Paul G Unschuld
    Max Planck Institute of Psychiatry, Kraepelinstr 2 10, 80804 München, Germany
    J Affect Disord 105:177-84. 2008
    ..Furthermore, GAL is involved in hypothalamic-hypophysiotropic signalling and cosecreted with luteinizing hormone-releasing hormone (LHRH), possibly acting as a mediator of estrogen action...
  42. doi request reprint Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression
    Manfred Uhr
    Max Planck Institute of Psychiatry, Kraepelinstr 10, 80804 Munich, Germany
    Neuron 57:203-9. 2008
    ..This finding can be viewed as a further step into personalized antidepressant treatment...
  43. doi request reprint Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder
    Martin E Keck
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Med Genet B Neuropsychiatr Genet 147:1196-204. 2008
    ..These data suggest that polymorphisms in the AVPR1B and the CRHR1 genes alter the susceptibility to panic disorder...
  44. pmc Replication and meta-analysis of TMEM132D gene variants in panic disorder
    A Erhardt
    Max Planck Institute of Psychiatry, Munich, Germany
    Transl Psychiatry 2:e156. 2012
    ..Our results also indicate that patient ascertainment and genetic background could be important sources of heterogeneity modifying this association signal in different populations...
  45. pmc The CRF system, stress, depression and anxiety-insights from human genetic studies
    E B Binder
    Max Planck Institute of Psychiatry, Munich, Germany
    Mol Psychiatry 15:574-88. 2010
    ..In-depth characterization of these variants will likely be important in furthering our understanding of the long-term consequences of adverse experience...
  46. ncbi request reprint Neurotensin receptor antagonist SR 142948A alters Fos expression and extrapyramidal side effect profile of typical and atypical antipsychotic drugs
    Elisabeth B Binder
    Laboratory of Neuropsychopharmacology, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA
    Neuropsychopharmacology 29:2200-7. 2004
    ..The effects of the NT receptor antagonist were paralleled by its effects on catalepsy in olanzapine--but not haloperidol--treated animals...
  47. ncbi request reprint The role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs
    E B Binder
    Max Planck Institute for Psychiatry, Munich, Germany
    Biol Psychiatry 50:856-72. 2001
    ..This review summarizes the evidence in support of a role for the NT system in both the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs...
  48. ncbi request reprint Toward a reliable distinction between patients with mild cognitive impairment and Alzheimer-type dementia versus major depression
    Anke Post
    Max Planck Institute of Psychiatry, Munich, Germany
    Biol Psychiatry 59:858-62. 2006
    ....
  49. ncbi request reprint Identification of molecules potentially involved in mediating the in vivo actions of the corticotropin-releasing hormone receptor 1 antagonist, NBI30775 (R121919)
    Anke Post
    Max Planck Institute of Psychiatry, Kraepelinstrasse 10, 80804 Munich, Germany
    Psychopharmacology (Berl) 180:150-8. 2005
    ..Despite its therapeutic efficacy, there is only little information about its mechanisms of action on cellular and molecular targets...
  50. pmc Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies
    Divya Mehta
    Max Planck Institute of Psychiatry, Kraepelinstrasse, Munich, Germany
    Arch Gen Psychiatry 68:901-10. 2011
    ..Polymorphisms in the gene encoding the glucocorticoid receptor (GR) regulating co-chaperone FKBP5 have been shown to alter GR sensitivity and are associated with an increased risk to develop posttraumatic stress disorder (PTSD)...
  51. ncbi request reprint Implications for the practice of psychiatry
    Elisabeth B Binder
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 101 Woodruff Circle, Suite 4000, Atlanta, GA 30322, USA
    Prog Brain Res 158:275-93. 2006
  52. ncbi request reprint Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression
    Johannes Schumacher
    Institute of Human Genetics, University of Bonn, Bonn
    Biol Psychiatry 58:307-14. 2005
    ....
  53. ncbi request reprint Polymorphisms of the glucocorticoid receptor gene and major depression
    Elisabeth F C van Rossum
    Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    Biol Psychiatry 59:681-8. 2006
    ..The N363S and BclI polymorphisms have been associated with hypersensitivity to glucocorticoids, whereas the ER22/23EK polymorphism is related to glucocorticoid resistance...
  54. ncbi request reprint Changes in the hypothalamic-pituitary-adrenal axis and leptin levels during antidepressant treatment
    Hubertus Himmerich
    Max Planck Institut fur Psychiatrie, Munchen, Deutschland
    Neuropsychobiology 55:28-35. 2007
    ..Glucocorticoids themselves are reported to increase leptin synthesis and secretion in humans...
  55. pmc Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene
    Rebekah G Bradley
    Atlanta VA Medical Center, Georgia, USA
    Arch Gen Psychiatry 65:190-200. 2008
    ..Child abuse and trauma alter the endogenous stress response, principally corticotropin-releasing hormone and its downstream effectors, suggesting that a gene x environment interaction at this locus may be important in depression...
  56. doi request reprint Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation
    Andreas Menke
    Am J Psychiatry 165:917-8. 2008
  57. ncbi request reprint Ziprasidone-related tardive dyskinesia
    Martin E Keck
    Am J Psychiatry 161:175-6. 2004