Aida M Andres
Affiliation: Max Planck Institute for Evolutionary Anthropology
- Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentationAida M Andres
Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA
PLoS Genet 6:e1001157. 2010..Although the precise selective pressure that maintains polymorphism is unknown, the demonstrated differences between the ERAP2 splice forms provide important insights into the potential mechanism for the action of selection...
- Reproduction and immunity-driven natural selection in the human WFDC locusZélia Ferreira
National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA
Mol Biol Evol 30:938-50. 2013..This study provides further evidence that the WFDC and SEMG loci have been under strong adaptive pressure within the short timescale of modern humans...