A Kispert

Summary

Affiliation: Max-Planck Institute of Immunobiology
Country: Germany

Publications

  1. ncbi request reprint Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney
    A Kispert
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Development 125:4225-34. 1998
  2. ncbi request reprint Pax-2 regulatory sequences that direct transgene expression in the developing neural plate and external granule cell layer of the cerebellum
    D H Rowitch
    Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Brain Res Dev Brain Res 117:99-108. 1999
  3. ncbi request reprint Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips
    A Kispert
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Development 122:3627-37. 1996
  4. ncbi request reprint GDNF induces branching and increased cell proliferation in the ureter of the mouse
    C V Pepicelli
    Biolabs, Harvard University, 16 Divinity Avenue, Cambridge, Massachusetts 02138, USA
    Dev Biol 192:193-8. 1997
  5. ncbi request reprint Female development in mammals is regulated by Wnt-4 signalling
    S Vainio
    Department of Molecular and Cellular Biology, The Biolabs, Harvard University, Cambridge, Massachusetts 02138, USA
    Nature 397:405-9. 1999
  6. ncbi request reprint A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse
    F L Conlon
    Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, MA 02138
    Development 120:1919-28. 1994
  7. ncbi request reprint A protein kinase encoded by the t complex responder gene causes non-mendelian inheritance
    B G Herrmann
    Max Planck Institute of Immunobiology, Freiburg, Germany
    Nature 402:141-6. 1999
  8. ncbi request reprint The mouse Rsk3 gene maps to the Leh66 elements carrying the t-complex responder Tcr
    A Kispert
    Max Planck Institut fur Immunbiologie, Abt Molekulare Embryologie, Stubeweg 51, 79108 Freiburg, Germany
    Mamm Genome 10:794-802. 1999
  9. ncbi request reprint sFRP-2 is a target of the Wnt-4 signaling pathway in the developing metanephric kidney
    B Lescher
    Max Planck Institut fur Immunbiologie, Abteilung für Molekulare Embryologie, Freiburg, Germany
    Dev Dyn 213:440-51. 1998
  10. ncbi request reprint Identification of a Wnt/beta-catenin signaling pathway in human thyroid cells
    K Helmbrecht
    Department of Clinical Endocrinology, Medizinische Hochschule Hannover, D-30625 Hannover, Germany
    Endocrinology 142:5261-6. 2001

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney
    A Kispert
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Development 125:4225-34. 1998
    ....
  2. ncbi request reprint Pax-2 regulatory sequences that direct transgene expression in the developing neural plate and external granule cell layer of the cerebellum
    D H Rowitch
    Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Brain Res Dev Brain Res 117:99-108. 1999
    ..Successful misexpression of Sonic hedgehog demonstrates that Pax-2 regulatory sequences should prove generally useful for transgenic gain-of-function approaches in mice...
  3. ncbi request reprint Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips
    A Kispert
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Development 122:3627-37. 1996
    ..We suggest that Wnt-11 acts as an autocrine factor within the ureter epithelium and that its expression is regulated at least in part by proteoglycans...
  4. ncbi request reprint GDNF induces branching and increased cell proliferation in the ureter of the mouse
    C V Pepicelli
    Biolabs, Harvard University, 16 Divinity Avenue, Cambridge, Massachusetts 02138, USA
    Dev Biol 192:193-8. 1997
    ..These results support a model in which GDNF supplied by the mesenchyme regulates growth and branching in the metanephric kidney through the local regulation of ureter tip-specific factors...
  5. ncbi request reprint Female development in mammals is regulated by Wnt-4 signalling
    S Vainio
    Department of Molecular and Cellular Biology, The Biolabs, Harvard University, Cambridge, Massachusetts 02138, USA
    Nature 397:405-9. 1999
    ..Wnt-4 may also be required for maintenance of the female germ line. Thus, the establishment of sexual dimorphism is under the control of both local and systemic signals...
  6. ncbi request reprint A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse
    F L Conlon
    Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, MA 02138
    Development 120:1919-28. 1994
    ..Data presented in this report demonstrate the involvement of a TGF beta-related molecule in axis formation in mammals...
  7. ncbi request reprint A protein kinase encoded by the t complex responder gene causes non-mendelian inheritance
    B G Herrmann
    Max Planck Institute of Immunobiology, Freiburg, Germany
    Nature 402:141-6. 1999
    ..Tcr transgene constructs cause non-mendelian transmission of chromosomes on which they are carried, which leads to sex-ratio distortion when Tcr cosegregates with the Y chromosome...
  8. ncbi request reprint The mouse Rsk3 gene maps to the Leh66 elements carrying the t-complex responder Tcr
    A Kispert
    Max Planck Institut fur Immunbiologie, Abt Molekulare Embryologie, Stubeweg 51, 79108 Freiburg, Germany
    Mamm Genome 10:794-802. 1999
    ..These data will facilitate the isolation of Tcr, a prerequisite for understanding transmission ratio distortion in mouse...
  9. ncbi request reprint sFRP-2 is a target of the Wnt-4 signaling pathway in the developing metanephric kidney
    B Lescher
    Max Planck Institut fur Immunbiologie, Abteilung für Molekulare Embryologie, Freiburg, Germany
    Dev Dyn 213:440-51. 1998
    ....
  10. ncbi request reprint Identification of a Wnt/beta-catenin signaling pathway in human thyroid cells
    K Helmbrecht
    Department of Clinical Endocrinology, Medizinische Hochschule Hannover, D-30625 Hannover, Germany
    Endocrinology 142:5261-6. 2001
    ..In summary, our data indicate that elements of the Wnt signaling pathway are expressed in thyroid cells and that this pathway is functionally active...
  11. ncbi request reprint Mutation of BSND causes Bartter syndrome with sensorineural deafness and kidney failure
    R Birkenhäger
    University Children s Hospital, Freiburg University, D 79106 Freiburg, Germany
    Nat Genet 29:310-4. 2001
    ..The gene encodes a hitherto unknown protein with two putative transmembrane alpha-helices and thus might function as a regulator for ion-transport proteins involved in aBS, or else as a new transporter or channel itself...
  12. ncbi request reprint Expression patterns of Wnt genes in mouse gut development
    H Lickert
    Department of Molecular Embryology, Max Planck Institute of Immunobiology, Stubeweg 51, D 79108, Freiburg, Germany
    Mech Dev 105:181-4. 2001
    ..5. Wnt11 is highly expressed at the gastro-esophageal junctions, while Wnt4 is found in the epithelium lining the pyloric region of the stomach but not in the epithelium of the prospective gland region...
  13. ncbi request reprint Embryonic expression of the murine homologue of SALL1, the gene mutated in Townes--Brocks syndrome
    A Buck
    Institut fur Humangenetik, Georg August Universitat Gottingen, Heinrich Düker Weg 12, 37073 Gottingen, Germany
    Mech Dev 104:143-6. 2001
    ..Other sites of expression include the meso- and metanephros, lens, olfactory bulbs, heart, primitive streak and the genital tubercle. Hence, Sall1 expression to a large degree reflects the structures affected in human TBS...
  14. ncbi request reprint Cloning and expression analysis of the mouse T-box gene tbx20
    F Kraus
    Max Planck Institut fur Immunbiologie, Abt Molekulare Embryologie, Stubeweg 51, 79108 Freiburg, Germany
    Mech Dev 100:87-91. 2001
    ..Expression is prominent in the extraembryonic mesoderm, in the developing heart, the eye anlage and motor neurons of hindbrain and spinal cord...
  15. ncbi request reprint Cloning and expression analysis of the mouse T-box gene Tbx18
    F Kraus
    Max Planck Institut fur Immunbiologie, Abt Molekulare Embryologie, Stubeweg 51, 79108 Freiburg, Germany
    Mech Dev 100:83-6. 2001
    ..Other sites of expression include the cranial paraxial mesoderm, the presomitic mesoderm, the anterior somite half, the genital ridge, and the developing limb buds...
  16. ncbi request reprint Nephrocystin: gene expression and sequence conservation between human, mouse, and Caenorhabditis elegans
    E Otto
    University Children s Hospital, Freiburg University, Germany
    J Am Soc Nephrol 11:270-82. 2000
    ..The previously described discrepancy between widespread tissue expression and the restriction of symptoms to the kidney has now been confirmed by an in-depth expression study...
  17. ncbi request reprint The T genes in embryogenesis
    B G Herrmann
    Max Planck Institut fur Entwicklungsbiologie, Abteilung Biochemie, Tubingen, Germany
    Trends Genet 10:280-6. 1994
    ..Homologous genes have been cloned from the frog Xenopus laevis, the zebrafish Brachydanio rerio and the ascidian Halocynthia roretzi. The T gene is an important tool for elucidating mesoderman and embryonic pattern formation...
  18. ncbi request reprint Homologs of the mouse Brachyury gene are involved in the specification of posterior terminal structures in Drosophila, Tribolium, and Locusta
    A Kispert
    Max Planck Institut fur Entwicklungsbiologie, Abteilung Biochemie, Tubingen, Germany
    Genes Dev 8:2137-50. 1994
    ..This conservation and the high similarity of T and Trg raise the question of a common evolutionary origin of the hindgut of insects and the notochord of chordates...
  19. ncbi request reprint A role for Pax-1 as a mediator of notochordal signals during the dorsoventral specification of vertebrae
    H Koseki
    Department of Developmental Biology, Max Planck Institute of Immunobiology, Freiburg, Germany
    Development 119:649-60. 1993
    ....
  20. ncbi request reprint Rescue of the tail defect of Brachyury mice
    D Stott
    Max Planck Institut fur Entwicklungsbiologie, Tubingen, Germany
    Genes Dev 7:197-203. 1993
    ..These data show the correlation of the level of T product with the extension of the anteroposterior axis, directly demonstrating the involvement of the T product in this process...
  21. ncbi request reprint Cloning and expression analysis of SALL4, the murine homologue of the gene mutated in Okihiro syndrome
    J Kohlhase
    Institut fur Humangenetik, Georg August Universitat Gottingen, Heinrich Düker Weg 12, 37073 Gottingen, Germany
    Cytogenet Genome Res 98:274-7. 2002
    ..Prominent expression in the developing midbrain, branchial arches and the limbs suggests an important function of SALL4 during development of these structures as expected from the observation in Okihiro syndrome patients...