Henry N ChapmanSummaryAffiliation: Max-Planck-Unit for Structural Molecular Biology Country: Germany Publications
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Publications
Taking X-ray diffraction to the limit: macromolecular structures from femtosecond X-ray pulses and diffraction microscopy of cells with synchrotron radiationJianwei Miao
Stanford Synchrotron Radiation Laboratory, Stanford Linear Accelerator Center, Stanford University, Stanford, California 94309 0210, USA
Annu Rev Biophys Biomol Struct 33:157-76. 2004....- Applied physics. Focus on x-ray diffractionHenry N Chapman
Centre for Free-Electron Laser Science, University of Hamburg and Deutsches Elektronen-Synchrotron, Notkestrasse 85, 22607 Hamburg, Germany
Science 321:352-3. 2008 
Femtosecond X-ray protein nanocrystallographyHenry N Chapman
Center for Free Electron Laser Science, DESY, Notkestrasse 85, 22607 Hamburg, Germany
Nature 470:73-7. 2011..This offers a new approach to structure determination of macromolecules that do not yield crystals of sufficient size for studies using conventional radiation sources or are particularly sensitive to radiation damage...- X-ray imaging beyond the limitsHenry N Chapman
Centre for Free Electron Laser Science, University of Hamburg, and DESY, Notkestrasse 85, 22607 Hamburg, Germany
Nat Mater 8:299-301. 2009..From recent experiments and simulations one can envisage imaging macromolecules with X-rays without the need for crystallization... - Time-resolved protein nanocrystallography using an X-ray free-electron laserAndrew Aquila
Center for Free Electron Laser Science, DESY, Notkestraße 85, 22607 Hamburg, Germany
Opt Express 20:2706-16. 2012..This technique opens the door to time-resolved structural studies of reaction dynamics in biological systems... 
Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laserLars Redecke
Joint Laboratory for Structural Biology of Infection and Inflammation, Institute of Biochemistry and Molecular Biology, University of Hamburg, and Institute of Biochemistry, University of Lubeck, at Deutsches Elektronen Synchrotron, Notkestrasse 85, 22607 Hamburg, Germany
Science 339:227-30. 2013....- Molecular imaging using x-ray free-electron lasersAnton Barty
Center for Free Electron Laser Science, DESY, 22607 Hamburg, Germany email
Annu Rev Phys Chem 64:415-35. 2013..New techniques for determining the structure of systems that cannot be crystallized and for studying the time-resolved behavior of irreversible reactions at femtosecond timescales are now available... - High-efficiency x-ray gratings with asymmetric-cut multilayersSasa Bajt
Photon Science, DESY, Hamburg, Germany
J Opt Soc Am A Opt Image Sci Vis 29:216-30. 2012..Both the Laue (transmitting) and Bragg (reflecting) geometries are incorporated in our formalism, which is applied to the analysis of multilayer Laue lenses and focusing and dispersing Bragg optics... - Modeling of the damage dynamics of nanospheres exposed to x-ray free-electron-laser radiationStefan P Hau-Riege
Lawrence Livermore National Laboratory, Livermore, CA 94551, USA
Phys Rev E Stat Nonlin Soft Matter Phys 77:041902. 2008..8-5 keV and low fluences, focusing particularly on macroscopic collective effects such as particle charging, expansion, and average ionization of nanospheres... - Encapsulation and diffraction-pattern-correction methods to reduce the effect of damage in x-ray diffraction imaging of single biological moleculesStefan P Hau-Riege
Lawrence Livermore National Laboratory, Livermore, CA 94551, USA
Phys Rev Lett 98:198302. 2007..Simulations show that these methods greatly improve the image quality... - High-resolution ab initio three-dimensional x-ray diffraction microscopyHenry N Chapman
University of California, Lawrence Livermore National Laboratory, 94550, USA
J Opt Soc Am A Opt Image Sci Vis 23:1179-200. 2006.... - Pulse requirements for x-ray diffraction imaging of single biological moleculesStefan P Hau-Riege
Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94551, USA
Phys Rev E Stat Nonlin Soft Matter Phys 71:061919. 2005..We discuss several means to alleviate the pulse requirements, and compare the requirements with parameters of two planned x-ray lasers... - SPEDEN: reconstructing single particles from their diffraction patternsStefan P Hau-Riege
Physics and Advance Technology, Lawrence Livermore National Laboratory, PO Box 808, Livermore, CA 94539, USA
Acta Crystallogr A 60:294-305. 2004..The program could be used for determining the structures of radiation-tolerant samples and, eventually, of large biological molecular structures without the need for crystallization...