T Ulrichs

Summary

Affiliation: Max-Planck-Institute for Infection Biology
Country: Germany

Publications

  1. ncbi Differential organization of the local immune response in patients with active cavitary tuberculosis or with nonprogressive tuberculoma
    Timo Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, Institute for Infection Medicine, Charite University Medicine, Campus Benjamin Franklin, Berlin, Germany
    J Infect Dis 192:89-97. 2005
  2. ncbi Mycobacterial persistence and immunity
    Timo Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, Schumannstrabe 21 22, 10117 Berlin, Germany
    Front Biosci 7:d458-69. 2002
  3. ncbi New insights into the function of granulomas in human tuberculosis
    Timo Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Pathol 208:261-9. 2006
  4. ncbi Human tuberculous granulomas induce peripheral lymphoid follicle-like structures to orchestrate local host defence in the lung
    Timo Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Pathol 204:217-28. 2004
  5. ncbi [Immunology of tuberculosis: impact on the development of novel vaccines]
    T Ulrichs
    Max Planck Institut für Infektionsbiologie, Berlin
    Internist (Berl) 44:1374-84. 2003
  6. pmc Increased numbers of ESAT-6- and purified protein derivative-specific gamma interferon-producing cells in subclinical and active tuberculosis infection
    T Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, 10117 Berlin, Germany
    Infect Immun 68:6073-6. 2000
  7. ncbi Numbers of IFN-gamma-producing cells against ESAT-6 increase in tuberculosis patients during chemotherapy
    T Ulrichs
    Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany
    Int J Tuberc Lung Dis 4:1181-3. 2000
  8. ncbi Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection
    Peter Seiler
    Max Planck Institut für Infektionsbiologie, Berlin, Germany
    J Infect Dis 188:1326-31. 2003
  9. pmc Loss of receptor on tuberculin-reactive T-cells marks active pulmonary tuberculosis
    Mathias Streitz
    Institut für Medizinische Immunologie der Charité, Charite Universitatsmedizin Berlin, Berlin, Germany
    PLoS ONE 2:e735. 2007
  10. ncbi Modified immunohistological staining allows detection of Ziehl-Neelsen-negative Mycobacterium tuberculosis organisms and their precise localization in human tissue
    Timo Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Pathol 205:633-40. 2005

Collaborators

  • Stefan He Kaufmann
  • M E Munk
  • T Schaberg
  • F Kern
  • Jean Laurent Casanova
  • Laurel Nomura
  • Rino Rappuoli
  • DAVID BRANCH MOODY
  • L Morawietz
  • V Krenn
  • Peter Malfertheiner
  • Mathias Streitz
  • Helmy Rachman
  • Christiane Schewe
  • Peter Seiler
  • Bernd Rosenkranz
  • Daniela Tornese
  • Viola Schultze
  • Deborah Novicki
  • Bruce F Scharschmidt
  • Emanuela Palla
  • Duccio Berti
  • Samuele Peppoloni
  • S I Behr-Perst
  • Giuseppe Del Giudice
  • Jitendra Ganju
  • Mario Contorni
  • Francesco Norelli
  • Holden Maecker
  • Ali Quassem
  • Gerd Liebetrau
  • Ali Yahyazadeh
  • Hans Dieter Volk
  • Rodica Lenkei
  • Vedat Yildirim
  • Lydia Tesfa
  • George A Kosmiadi
  • David Eisenberg
  • Hans Mollenkopf
  • Michael Strong
  • Leander Grode
  • Johannes Schuchhardt
  • Gustavo B Baretton
  • Manfred Dietel
  • Marianne Grosser
  • Stefan Pahl
  • Torsten Goldmann
  • Karsten Schluns
  • Albert Zink
  • Iver Petersen
  • Andreas Nerlich
  • Ekkehard Vollmer
  • Sabine Jorg
  • Lydia Pradl
  • Silke Bandermann
  • Peter Aichele
  • R J Schulz

Detail Information

Publications16

  1. ncbi Differential organization of the local immune response in patients with active cavitary tuberculosis or with nonprogressive tuberculoma
    Timo Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, Institute for Infection Medicine, Charite University Medicine, Campus Benjamin Franklin, Berlin, Germany
    J Infect Dis 192:89-97. 2005
    ..Failure of this containment leads to reactivation of postprimary tuberculosis (TB). The regional immune processes that sustain the delicate balance with persistent M. tuberculosis, however, remain unclear...
  2. ncbi Mycobacterial persistence and immunity
    Timo Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, Schumannstrabe 21 22, 10117 Berlin, Germany
    Front Biosci 7:d458-69. 2002
    ..The following article reviews our knowledge about both pathogen and host mechanisms involved in the immune response to M. tuberculosis...
  3. ncbi New insights into the function of granulomas in human tuberculosis
    Timo Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Pathol 208:261-9. 2006
    ..These findings lead to a revised view of the regional immune response in human tuberculosis. Novel insights into this dynamic cross-talk form the basis of novel intervention strategies...
  4. ncbi Human tuberculous granulomas induce peripheral lymphoid follicle-like structures to orchestrate local host defence in the lung
    Timo Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Pathol 204:217-28. 2004
    ..It is concluded that the follicular structures in the peripheral rim of granulomas serve as a morphological substrate for the orchestration of the enduring host response in pulmonary tuberculosis...
  5. ncbi [Immunology of tuberculosis: impact on the development of novel vaccines]
    T Ulrichs
    Max Planck Institut für Infektionsbiologie, Berlin
    Internist (Berl) 44:1374-84. 2003
    ..A new vaccine should elicit a better immune response than the natural infection and reliably protect from TB disease, regardless if given prior or post infection with M. tuberculosis...
  6. pmc Increased numbers of ESAT-6- and purified protein derivative-specific gamma interferon-producing cells in subclinical and active tuberculosis infection
    T Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, 10117 Berlin, Germany
    Infect Immun 68:6073-6. 2000
    ..Thus, ESAT-6 is a potential candidate for use in detection of early, as well as active, tuberculosis and for control of the disease...
  7. ncbi Numbers of IFN-gamma-producing cells against ESAT-6 increase in tuberculosis patients during chemotherapy
    T Ulrichs
    Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany
    Int J Tuberc Lung Dis 4:1181-3. 2000
    ..These results indicate that monitoring specific M. tuberculosis antigen reactivity during anti-tuberculosis chemotherapy may avoid premature termination of treatment and resistant strains...
  8. ncbi Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection
    Peter Seiler
    Max Planck Institut für Infektionsbiologie, Berlin, Germany
    J Infect Dis 188:1326-31. 2003
    ..bovis Bacille-Calmette-Guérin serum continued with persistence of infection. These findings have important implications for diagnosis, as well as for both chemotherapy and development of vaccine strategies.'..
  9. pmc Loss of receptor on tuberculin-reactive T-cells marks active pulmonary tuberculosis
    Mathias Streitz
    Institut für Medizinische Immunologie der Charité, Charite Universitatsmedizin Berlin, Berlin, Germany
    PLoS ONE 2:e735. 2007
    ..This includes surface marker expression and functionality of mycobacterial antigen specific T-cells...
  10. ncbi Modified immunohistological staining allows detection of Ziehl-Neelsen-negative Mycobacterium tuberculosis organisms and their precise localization in human tissue
    Timo Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Pathol 205:633-40. 2005
    ..The positive pAbBCG staining results were confirmed either by PCR analysis of microdissected stained tissue or by culture from tissue. This immunostaining approach allows precise localization of the pathogen in infected tissue...
  11. ncbi Phenotypically activated gammadelta T lymphocytes in the peripheral blood of patients with tuberculosis
    S I Behr-Perst
    Max Planck Institute for Infection Biology, Department of Immunology, 10117 Berlin, Germany
    J Infect Dis 180:141-9. 1999
    ..The activation phenotype of peripheral gammadelta T cells in patients with tuberculosis emphasizes the role of these T cells in controlling the inflammatory process during tuberculosis and perhaps other microbial infections...
  12. ncbi Variable outcome of experimental interferon-gamma therapy of disseminated Bacillus Calmette-Guerin infection in two unrelated interleukin-12Rbeta1-deficient Slovakian children
    Timo Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    Eur J Pediatr 164:166-72. 2005
    ....
  13. pmc Unique transcriptome signature of Mycobacterium tuberculosis in pulmonary tuberculosis
    Helmy Rachman
    Max Planck Institute for Infection, Immunology, Schumannstrasse 21 22, Berlin 10117, Germany
    Infect Immun 74:1233-42. 2006
    ..tuberculosis actively transcribes a number of genes involved in active fortification and evasion from host defense systems. These genes may provide targets for novel intervention strategies...
  14. pmc T-cell responses to CD1-presented lipid antigens in humans with Mycobacterium tuberculosis infection
    Timo Ulrichs
    Department of Microbiology and Immunology, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York 10461, USA
    Infect Immun 71:3076-87. 2003
    ..tuberculosis-reactive T cells in healthy individuals with previous exposure to M. tuberculosis...
  15. ncbi Inter-laboratory validation of PCR-based detection of Mycobacterium tuberculosis in formalin-fixed, paraffin-embedded tissues
    Christiane Schewe
    Charite Campus Mitte, Institute of Pathology, Universitatsmedizin Berlin, Schumannstr 20 21, 10098 Berlin, Germany
    Virchows Arch 447:573-85. 2005
    ..oligene.com/). All molecular pathology laboratories are invited to participate in this quality assurance initiative...
  16. doi Safety and immunogenicity of an intramuscular Helicobacter pylori vaccine in noninfected volunteers: a phase I study
    Peter Malfertheiner
    Otto von Guericke Universitaet, Department of Gastroenterology, Hepatology and Infectious Diseases, Magdeburg, Germany
    Gastroenterology 135:787-95. 2008
    ....