P Seiler

Summary

Affiliation: Max-Planck-Institute for Infection Biology
Country: Germany

Publications

  1. ncbi request reprint In vivo selection of neutralization-resistant virus variants but no evidence of B cell tolerance in lymphocytic choriomeningitis virus carrier mice expressing a transgenic virus-neutralizing antibody
    P Seiler
    Institute of Experimental Immunology, Department of Pathology, University of Zurich, Switzerland
    J Immunol 162:4536-41. 1999
  2. pmc Additive effect of neutralizing antibody and antiviral drug treatment in preventing virus escape and persistence
    P Seiler
    Department of Pathology, Institute of Experimental Immunology, University of Zurich, Switzerland
    J Virol 74:5896-901. 2000
  3. ncbi request reprint Crucial role of marginal zone macrophages and marginal zone metallophils in the clearance of lymphocytic choriomeningitis virus infection
    P Seiler
    Department of Pathology, University Hospital Zurich, Switzerland
    Eur J Immunol 27:2626-33. 1997
  4. pmc Enhanced virus clearance by early inducible lymphocytic choriomeningitis virus-neutralizing antibodies in immunoglobulin-transgenic mice
    P Seiler
    Department of Pathology, Institute of Experimental Immunology, University of Zurich, Switzerland
    J Virol 72:2253-8. 1998
  5. ncbi request reprint Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
    D Kagi
    Department of Pathology, University of Zurich, Switzerland
    Nature 369:31-7. 1994
  6. pmc Limited mycobacterial infection of the liver as a consequence of its microanatomical structure causing restriction of mycobacterial growth to professional phagocytes
    P Seiler
    Max Planck Institute for Infection Biology, D-10117 Berlin, Germany
    Infect Immun 69:7922-6. 2001
  7. ncbi request reprint Autoimmune intestinal pathology induced by hsp60-specific CD8 T cells
    U Steinhoff
    Department of Immunology, Max Planck Institute of Infection Biology, Germany
    Immunity 11:349-58. 1999
  8. ncbi request reprint Decontamination with vaporized hydrogen peroxide is effective against Mycobacterium tuberculosis
    A Kahnert
    Max Planck Institute for Infection Biology, Berlin, Germany
    Lett Appl Microbiol 40:448-52. 2005
  9. pmc Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice
    D Kagi
    Ontario Cancer Institute, Toronto M5G2M9, Canada
    J Exp Med 186:989-97. 1997
  10. ncbi request reprint Rabbit small intestinal trehalase. Purification, cDNA cloning, expression, and verification of glycosylphosphatidylinositol anchoring
    J Ruf
    Department of Biochemistry II, Swiss Federal Institute of Technology, Eidgenössische Technische Hochschule Zentrum, Zurich, Switzerland
    J Biol Chem 265:15034-9. 1990

Collaborators

Detail Information

Publications10

  1. ncbi request reprint In vivo selection of neutralization-resistant virus variants but no evidence of B cell tolerance in lymphocytic choriomeningitis virus carrier mice expressing a transgenic virus-neutralizing antibody
    P Seiler
    Institute of Experimental Immunology, Department of Pathology, University of Zurich, Switzerland
    J Immunol 162:4536-41. 1999
    ....
  2. pmc Additive effect of neutralizing antibody and antiviral drug treatment in preventing virus escape and persistence
    P Seiler
    Department of Pathology, Institute of Experimental Immunology, University of Zurich, Switzerland
    J Virol 74:5896-901. 2000
    ..Similar additive effects may be unexpectedly efficient and beneficial in humans after infections with persistent viruses such as hepatitis C virus and hepatitis B virus and possibly human immunodeficiency virus...
  3. ncbi request reprint Crucial role of marginal zone macrophages and marginal zone metallophils in the clearance of lymphocytic choriomeningitis virus infection
    P Seiler
    Department of Pathology, University Hospital Zurich, Switzerland
    Eur J Immunol 27:2626-33. 1997
    ..These findings suggest that MZM and MM play a crucial role in the early control of a LCMV infection by preventing immediate virus spread to peripheral organs, but are not essential for the induction of the LCMV-specific CTL response...
  4. pmc Enhanced virus clearance by early inducible lymphocytic choriomeningitis virus-neutralizing antibodies in immunoglobulin-transgenic mice
    P Seiler
    Department of Pathology, Institute of Experimental Immunology, University of Zurich, Switzerland
    J Virol 72:2253-8. 1998
    ..c. LCMV infection. Thus, early-inducible LCMV-neutralizing antibodies can contribute to viral clearance in the acute phase of the infection and do not cause antibody-dependent enhancement of disease...
  5. ncbi request reprint Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
    D Kagi
    Department of Pathology, University of Zurich, Switzerland
    Nature 369:31-7. 1994
    ..The mice fail to clear lymphocytic choriomeningitis virus and they eliminate fibrosarcoma tumour cells with reduced efficiency. Perforin is therefore a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis...
  6. pmc Limited mycobacterial infection of the liver as a consequence of its microanatomical structure causing restriction of mycobacterial growth to professional phagocytes
    P Seiler
    Max Planck Institute for Infection Biology, D-10117 Berlin, Germany
    Infect Immun 69:7922-6. 2001
    ..Unlike in organs more persistently seeded by M. tuberculosis, in the liver the bacteria do not infect cell types other than professional phagocytes...
  7. ncbi request reprint Autoimmune intestinal pathology induced by hsp60-specific CD8 T cells
    U Steinhoff
    Department of Immunology, Max Planck Institute of Infection Biology, Germany
    Immunity 11:349-58. 1999
    ..This report demonstrates that CD8 T cells with defined antigen specificity cause intestinal inflammation, emphasizing a link between infection and autoimmune disease...
  8. ncbi request reprint Decontamination with vaporized hydrogen peroxide is effective against Mycobacterium tuberculosis
    A Kahnert
    Max Planck Institute for Infection Biology, Berlin, Germany
    Lett Appl Microbiol 40:448-52. 2005
    ..To determine the efficacy of room fumigation with vaporized hydrogen peroxide (VHP) in decontamination of viable Mycobacterium tuberculosis...
  9. pmc Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice
    D Kagi
    Ontario Cancer Institute, Toronto M5G2M9, Canada
    J Exp Med 186:989-97. 1997
    ..However, in the absence of perforin chronic inflammation of the islets can lead to diabetogenic beta cell loss by less efficient secondary effector mechanisms...
  10. ncbi request reprint Rabbit small intestinal trehalase. Purification, cDNA cloning, expression, and verification of glycosylphosphatidylinositol anchoring
    J Ruf
    Department of Biochemistry II, Swiss Federal Institute of Technology, Eidgenössische Technische Hochschule Zentrum, Zurich, Switzerland
    J Biol Chem 265:15034-9. 1990
    ..This strongly suggests that rabbit small intestinal trehalase is anchored via glycosylphosphatidylinositol also when expressed in X. laevis oocytes...