Affiliation: Max-Planck-Institute for Infection Biology
Knoll M, Yanagisawa Y, Simmons S, Engels N, Wienands J, Melchers F, et al. The non-Ig parts of the VpreB and ?5 proteins of the surrogate light chain play opposite roles in the surface representation of the precursor B cell receptor. J Immunol. 2012;188:6010-7 pubmed publisher
..By contrast, the non-Ig part of ?5 crosslinks preBCRs for downregulation and stimulation. ..