P R Jungblut

Summary

Affiliation: Max-Planck-Institute for Infection Biology
Country: Germany

Publications

  1. ncbi Proteomics in human disease: cancer, heart and infectious diseases
    P R Jungblut
    Max Planck Institut für Infektionsbiologie, Protein Analyse Einheit, Berlin, Germany
    Electrophoresis 20:2100-10. 1999
  2. pmc Proteomic identification of secreted proteins of Propionibacterium acnes
    Carsten Holland
    Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany
    BMC Microbiol 10:230. 2010
  3. pmc Calibration of mass spectrometric peptide mass fingerprint data without specific external or internal calibrants
    Witold E Wolski
    Max Planck Institute for Molecular Genetics, Ihnestrasse 63 73, D 14195 Berlin, Germany
    BMC Bioinformatics 6:203. 2005
  4. doi Helicobacter pylori proteomics by 2-DE/MS, 1-DE-LC/MS and functional data mining
    Peter R Jungblut
    Core Facility Protein Analysis, Max Planck Institute for Infection Biology, 10117 Berlin, Germany
    Proteomics 10:182-93. 2010
  5. doi Towards the analysis of protein species: an overview about strategies and methods
    Peter R Jungblut
    Core Facility Protein Analysis, Max Planck Institute for Infection Biology, Chariteplatz 1, 10117, Berlin, Germany
    Amino Acids 41:219-22. 2011
  6. ncbi Proteome analysis of bacterial pathogens
    P R Jungblut
    Max Planck Institute for Infection Biology, Support Unit for Biochemistry, Schumann Str 21 22, 10117, Berlin, Germany
    Microbes Infect 3:831-40. 2001
  7. ncbi Comparative proteome analysis of Helicobacter pylori
    P R Jungblut
    Max Planck Institute for Infection Biology, Central Support Unit Biochemistry, Berlin, Germany
    Mol Microbiol 36:710-25. 2000
  8. ncbi Comprehensive detection of immunorelevant Borrelia garinii antigens by two-dimensional electrophoresis
    P R Jungblut
    Institute of Microbiology, Medical Faculty, University Innsbruck, Austria
    Electrophoresis 20:3611-22. 1999
  9. ncbi Comparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: towards functional genomics of microbial pathogens
    P R Jungblut
    Protein Analysis Unit, Max Planck Institute for Infection Biology, Berlin, Germany
    Mol Microbiol 33:1103-17. 1999
  10. ncbi Identification of proteins from Mycobacterium tuberculosis missing in attenuated Mycobacterium bovis BCG strains
    J Mattow
    Max-Planck-Institute for Infection Biology, Berlin, Germany
    Electrophoresis 22:2936-46. 2001

Collaborators

Detail Information

Publications26

  1. ncbi Proteomics in human disease: cancer, heart and infectious diseases
    P R Jungblut
    Max Planck Institut für Infektionsbiologie, Protein Analyse Einheit, Berlin, Germany
    Electrophoresis 20:2100-10. 1999
    ..Similarly, antibody reactivity to seven different marker antigens of T. gondii allowed differentiation between acute and latent toxoplasmosis, an important diagnostic tool in both pregnancy and immunosuppressed patients...
  2. pmc Proteomic identification of secreted proteins of Propionibacterium acnes
    Carsten Holland
    Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany
    BMC Microbiol 10:230. 2010
    ..acnes virulence factors remains scarce. Here, we identified proteins secreted during anaerobic cultivation of a range of skin and clinical P. acnes isolates, spanning the four known phylogenetic groups...
  3. pmc Calibration of mass spectrometric peptide mass fingerprint data without specific external or internal calibrants
    Witold E Wolski
    Max Planck Institute for Molecular Genetics, Ihnestrasse 63 73, D 14195 Berlin, Germany
    BMC Bioinformatics 6:203. 2005
    ..It relies on the comparison between experimentally determined and theoretical mass spectra. The PMF process requires calibration, usually performed with external or internal calibrants of known molecular masses...
  4. doi Helicobacter pylori proteomics by 2-DE/MS, 1-DE-LC/MS and functional data mining
    Peter R Jungblut
    Core Facility Protein Analysis, Max Planck Institute for Infection Biology, 10117 Berlin, Germany
    Proteomics 10:182-93. 2010
    ..Access to the PROMPT-generated diagrams in the Proteome Database allows the mining of experimental data with respect to other functional aspects...
  5. doi Towards the analysis of protein species: an overview about strategies and methods
    Peter R Jungblut
    Core Facility Protein Analysis, Max Planck Institute for Infection Biology, Chariteplatz 1, 10117, Berlin, Germany
    Amino Acids 41:219-22. 2011
    ..For determining the function of defined protein species a closer cooperation between cell biologists and proteomics experts is desirable...
  6. ncbi Proteome analysis of bacterial pathogens
    P R Jungblut
    Max Planck Institute for Infection Biology, Support Unit for Biochemistry, Schumann Str 21 22, 10117, Berlin, Germany
    Microbes Infect 3:831-40. 2001
    ..Immunoproteomics identifies specific and nonspecific antigens. For the management of the huge data amounts, bioinformatics is a valuable instrument for the construction of complex protein databases...
  7. ncbi Comparative proteome analysis of Helicobacter pylori
    P R Jungblut
    Max Planck Institute for Infection Biology, Central Support Unit Biochemistry, Berlin, Germany
    Mol Microbiol 36:710-25. 2000
    ..This basic knowledge of the proteome in the public domain will be an effective instrument for the identification of new virulence or pathogenic factors, and antigens of potentially diagnostic or curative value against H. pylori...
  8. ncbi Comprehensive detection of immunorelevant Borrelia garinii antigens by two-dimensional electrophoresis
    P R Jungblut
    Institute of Microbiology, Medical Faculty, University Innsbruck, Austria
    Electrophoresis 20:3611-22. 1999
    ..A 2-DE database of B. garinii was built up and is available on the World Wide Web (http://www.mpiib-berlin.mpg.de/2D-PAGE)...
  9. ncbi Comparative proteome analysis of Mycobacterium tuberculosis and Mycobacterium bovis BCG strains: towards functional genomics of microbial pathogens
    P R Jungblut
    Protein Analysis Unit, Max Planck Institute for Infection Biology, Berlin, Germany
    Mol Microbiol 33:1103-17. 1999
    ..It is to be hoped that the availability of the mycobacterial proteome will facilitate the design of novel measures for prevention and therapy of one of the great health threats, tuberculosis...
  10. ncbi Identification of proteins from Mycobacterium tuberculosis missing in attenuated Mycobacterium bovis BCG strains
    J Mattow
    Max-Planck-Institute for Infection Biology, Berlin, Germany
    Electrophoresis 22:2936-46. 2001
    ..bovis BCG. The remaining 20 spots unique for M. tuberculosis were identified as proteins encoded by genes that are not known to be missing in M. bovis BCG...
  11. ncbi A dynamic two-dimensional polyacrylamide gel electrophoresis database: the mycobacterial proteome via Internet
    H J Mollenkopf
    Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany
    Electrophoresis 20:2172-80. 1999
    ..Furthermore, the database facilitates not only interactive use, but also worldwide active participation of other scientific groups with their own data, requiring only minimal computer hardware and knowledge of information technology...
  12. ncbi Proteome analysis of the common human pathogen Helicobacter pylori
    D Bumann
    Max Planck Institute for Infection Biology, Department of Molecular Biology, Schumannstrasse 21 22, 10117 Berlin, Germany
    Proteomics 1:473-9. 2001
    ..The results that have been obtained led to a more detailed understanding of the Helicobacter biology and pathology and open further interesting fields for future work...
  13. ncbi Identification of a tyrosine-phosphorylated 35 kDa carboxy-terminal fragment (p35CagA) of the Helicobacter pylori CagA protein in phagocytic cells: processing or breakage?
    S Moese
    Max Planck Institut für Infektionsbiologie, Abt, Molekulare Biologie, Schumannstr 20 21, D 10117 Berlin, Germany
    Proteomics 1:618-29. 2001
    ..The possible function of CagA in host signal transduction and development of gastric disease is discussed...
  14. pmc Proteomics reveals open reading frames in Mycobacterium tuberculosis H37Rv not predicted by genomics
    P R Jungblut
    Core Facility for Protein Analysis, Max Planck Institute for Infection Biology, Berlin, Germany
    Infect Immun 69:5905-7. 2001
    ....
  15. ncbi Identification of acidic, low molecular mass proteins of Mycobacterium tuberculosis strain H37Rv by matrix-assisted laser desorption/ionization and electrospray ionization mass spectrometry
    J Mattow
    Max Planck Institute for Infection Biology, Department of Immunology, Schumannstr 21 22, D 10117 Berlin, Germany
    Proteomics 1:494-507. 2001
    ..Six additional spots were shown to comprise proteins encoded by open reading frames that have not been predicted for M. tuberculosis H37Rv by genomic investigations...
  16. ncbi Analysis of missed cleavage sites, tryptophan oxidation and N-terminal pyroglutamylation after in-gel tryptic digestion
    B Thiede
    Max Planck Institut für Infektionsbiologie, Monbijoustrasse 2, D 10117 Berlin, Germany
    Rapid Commun Mass Spectrom 14:496-502. 2000
    ..These data can be used for the refinement of protein searches by peptide mass fingerprinting...
  17. ncbi Matrix-assisted laser desorption-ionization mass spectrometry peptide mass fingerprinting for proteome analysis: identification efficiency after on-blot or in-gel digestion with and without desalting procedures
    S Lamer
    Max-Planck-Institute for Infection Biology, Central Support Unit Biochemistry, Berlin, Germany
    J Chromatogr B Biomed Sci Appl 752:311-22. 2001
    ..Whereas higher signal intensities resulted after concentration, hydrophilic peptides are better detected by direct measurement of the peptide mix without POROS R2 concentration...
  18. ncbi The necessity of functional proteomics: protein species and molecular function elucidation exemplified by in vivo alpha A crystallin N-terminal truncation
    W Hoehenwarter
    Max Planck Institute for Infection Biology, Core Facility Protein Analysis, Berlin, Germany
    Amino Acids 31:317-23. 2006
    ..We assess the present state of technology and suggest a shift in resources and paradigm for the routine attainment of the protein species level in proteomics...
  19. ncbi Immunization with gp96 from Listeria monocytogenes-infected mice is due to N-formylated listerial peptides
    A M Sponaas
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Immunol 167:6480-6. 2001
    ..We assume a unique role of gp96 in Ag processing through the H2-M3 pathway...
  20. ncbi Eye lens proteomics
    W Hoehenwarter
    Max Planck Institute for Infection Biology, Core Facility Protein Analysis, Berlin, Germany
    Amino Acids 30:369-89. 2006
    ..Proteomics methodology is therefore ideal to further comprehensive understanding of this organ and the factors involved in cataractogenesis...
  21. ncbi Tyrosine phosphorylation patterns and size modification of the Helicobacter pylori CagA protein after translocation into gastric epithelial cells
    S Backert
    , Abt. Molekulare Biologie, Schumannstr. 20/21, D-10117 Berlin, Germany
    Proteomics 1:608-17. 2001
    ..Translocation, tyrosine phosphorylation and size modification of CagA might be involved in host signal transduction and development of gastric disease...
  22. ncbi Separation and identification of human heart proteins
    D Jager
    Department of Medicine III, Martin Luther University, Halle Wittenberg, Germany
    J Chromatogr B Analyt Technol Biomed Life Sci 771:131-53. 2002
    ..In concert with genomic data functional proteomics will hold the key for a better understanding and therapeutical management of cardiovascular diseases in the future...
  23. ncbi Proteome analysis of rat hepatomas: carcinogen-dependent tumor-associated protein variants
    E Zeindl-Eberhart
    Institute of Pathology, University of Munich, Germany
    Electrophoresis 22:3009-18. 2001
    ..The hypothesis is proposed that carcinogens leave specific fingerprints at the proteome level of manifest liver tumors...
  24. ncbi Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions
    A Villarino
    Unité de Biochimie Structurale URA 2185 CNRS, Institut Pasteur, Paris, France
    J Mol Biol 350:953-63. 2005
    ..The ensuing model of PknB-GarA interactions suggests a substrate recruitment mechanism that might apply to other mycobacterial kinases bearing multiple phosphorylation sites in their activation loops...