Daniel Falush

Summary

Affiliation: Max-Planck-Institute for Infection Biology
Country: Germany

Publications

  1. pmc Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies
    Daniel Falush
    Department of Molecular Biology, Max Planck Institut für Infektionsbiologie, Schumann Strasse 21 22, 10117 Berlin, Germany
    Genetics 164:1567-87. 2003
  2. pmc An African origin for the intimate association between humans and Helicobacter pylori
    Bodo Linz
    Department of Molecular Biology, Max Planck Institut für Infektionsbiologie, D 10117 Berlin, Germany
    Nature 445:915-8. 2007
  3. pmc Microevolution of Helicobacter pylori during prolonged infection of single hosts and within families
    Giovanna Morelli
    Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany
    PLoS Genet 6:e1001036. 2010
  4. pmc Distinguishing human ethnic groups by means of sequences from Helicobacter pylori: lessons from Ladakh
    Thierry Wirth
    Department of Molecular Biology, Max Planck Institut für Infektionsbiologie, Schumannstrasse 21 22, 10117 Berlin, Germany
    Proc Natl Acad Sci U S A 101:4746-51. 2004
  5. ncbi Traces of human migrations in Helicobacter pylori populations
    Daniel Falush
    Department of Molecular Biology, Max Planck Institut für Infektionsbiologie, 10117 Berlin, Germany
    Science 299:1582-5. 2003
  6. pmc Sex and virulence in Escherichia coli: an evolutionary perspective
    Thierry Wirth
    Department of Molecular Biology, Schumannstrasse 21 22, Max Planck Institut für Infektionsbiologie, 10117 Berlin, Germany
    Mol Microbiol 60:1136-51. 2006
  7. ncbi Origin of extant domesticated sunflowers in eastern North America
    Abigail V Harter
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    Nature 430:201-5. 2004
  8. pmc Hybrid Vibrio vulnificus
    Naiel Bisharat
    University of Oxford, Oxford, United Kingdom
    Emerg Infect Dis 11:30-5. 2005
  9. pmc Inferring human colonization history using a copying model
    Garrett Hellenthal
    Department of Statistics, University of Oxford, Oxford, United Kingdom
    PLoS Genet 4:e1000078. 2008
  10. pmc A bimodal pattern of relatedness between the Salmonella Paratyphi A and Typhi genomes: convergence or divergence by homologous recombination?
    Xavier Didelot
    Department of Statistics, University of Oxford, Oxford OX1 3SY, United Kingdom
    Genome Res 17:61-8. 2007

Collaborators

Detail Information

Publications18

  1. pmc Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies
    Daniel Falush
    Department of Molecular Biology, Max Planck Institut für Infektionsbiologie, Schumann Strasse 21 22, 10117 Berlin, Germany
    Genetics 164:1567-87. 2003
    ..The methods are implemented in a program, structure, version 2.0, which is available at http://pritch.bsd.uchicago.edu...
  2. pmc An African origin for the intimate association between humans and Helicobacter pylori
    Bodo Linz
    Department of Molecular Biology, Max Planck Institut für Infektionsbiologie, D 10117 Berlin, Germany
    Nature 445:915-8. 2007
    ..pylori before their migrations from Africa and demonstrate that H. pylori has remained intimately associated with their human host populations ever since...
  3. pmc Microevolution of Helicobacter pylori during prolonged infection of single hosts and within families
    Giovanna Morelli
    Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany
    PLoS Genet 6:e1001036. 2010
    ..Comparisons with the recent literature show that short-term mutation rates vary dramatically in different bacterial species and can span a range of several orders of magnitude...
  4. pmc Distinguishing human ethnic groups by means of sequences from Helicobacter pylori: lessons from Ladakh
    Thierry Wirth
    Department of Molecular Biology, Max Planck Institut für Infektionsbiologie, Schumannstrasse 21 22, 10117 Berlin, Germany
    Proc Natl Acad Sci U S A 101:4746-51. 2004
    ..H. pylori sequence analysis has the potential to become an important tool for unraveling short-term genetic changes in human populations...
  5. ncbi Traces of human migrations in Helicobacter pylori populations
    Daniel Falush
    Department of Molecular Biology, Max Planck Institut für Infektionsbiologie, 10117 Berlin, Germany
    Science 299:1582-5. 2003
    ..Subsequent spread can be attributed to human migratory fluxes such as the prehistoric colonization of Polynesia and the Americas, the neolithic introduction of farming to Europe, the Bantu expansion within Africa, and the slave trade...
  6. pmc Sex and virulence in Escherichia coli: an evolutionary perspective
    Thierry Wirth
    Department of Molecular Biology, Schumannstrasse 21 22, Max Planck Institut für Infektionsbiologie, 10117 Berlin, Germany
    Mol Microbiol 60:1136-51. 2006
    ..This long-term pattern of evolution was observed in genes distributed throughout the genome, and thereby is the likely result of episodic selection for strains that can escape the host immune response...
  7. ncbi Origin of extant domesticated sunflowers in eastern North America
    Abigail V Harter
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    Nature 430:201-5. 2004
    ..We show that extant domesticates arose in eastern North America, with a substantial genetic bottleneck occurring during domestication...
  8. pmc Hybrid Vibrio vulnificus
    Naiel Bisharat
    University of Oxford, Oxford, United Kingdom
    Emerg Infect Dis 11:30-5. 2005
    ..This novel observation shows yet another way in which epidemic organisms arise...
  9. pmc Inferring human colonization history using a copying model
    Garrett Hellenthal
    Department of Statistics, University of Oxford, Oxford, United Kingdom
    PLoS Genet 4:e1000078. 2008
    ..A detailed depiction of the peopling of the world is available in animated form...
  10. pmc A bimodal pattern of relatedness between the Salmonella Paratyphi A and Typhi genomes: convergence or divergence by homologous recombination?
    Xavier Didelot
    Department of Statistics, University of Oxford, Oxford OX1 3SY, United Kingdom
    Genome Res 17:61-8. 2007
    ..We propose that recombination between Typhi and Paratyphi A has allowed the exchange of gene variants that are important for their adaptation to their common ecological niche, the human host...
  11. doi Convergence of Campylobacter species: implications for bacterial evolution
    Samuel K Sheppard
    Departments of Zoology and Statistics, University of Oxford, Peter Medawar Building, South Parks Road, Oxford OX1 3SY, UK
    Science 320:237-9. 2008
    ..Bacterial speciation can therefore occur by mechanisms analogous to those seen in metazoans, where genetic diversification and incipient speciation caused by ecological factors have been reported in several genera...
  12. ncbi Plastic cells and populations: DNA substrate characteristics in Helicobacter pylori transformation define a flexible but conservative system for genomic variation
    Steven M Levine
    Dept of Medicine, New York University School of Medicine, New York, NY 10016, USA
    FASEB J 21:3458-67. 2007
    ..pylori population biology...
  13. pmc Host-associated genetic import in Campylobacter jejuni
    Noel D McCarthy
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    Emerg Infect Dis 13:267-72. 2007
    ..Assignment using this signature enables improved prediction of source for pathogens that undergo frequent genetic recombination...
  14. pmc Genomic changes during chronic Helicobacter pylori infection
    Christian Kraft
    Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    J Bacteriol 188:249-54. 2006
    ..These results suggest that adaptation of H. pylori to the host individual may principally occur through sequence changes rather than loss or gain of genes...
  15. pmc Inference of bacterial microevolution using multilocus sequence data
    Xavier Didelot
    Department of Statistics, University of Oxford, Oxford OX1 3SY, United Kingdom
    Genetics 175:1251-66. 2007
    ..The software used in this article, ClonalFrame, is available from http://bacteria.stats.ox.ac.uk/...
  16. pmc Sequence typing and comparison of population biology of Campylobacter coli and Campylobacter jejuni
    Kate E Dingle
    Nuffield Department of Clinical Sciences, Oxford University, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    J Clin Microbiol 43:340-7. 2005
    ..The use of a common MLST scheme allows direct comparisons of the population biology and molecular epidemiology of these two closely related human pathogens...
  17. ncbi Genome-wide association mapping in bacteria?
    Daniel Falush
    Peter Medawar Building for Pathogen Research, South Parks Road, Oxford OX1 3SY, UK
    Trends Microbiol 14:353-5. 2006
    ..Here, we describe how association mapping could be successfully applied to bacteria and outline the necessary sampling and genotyping strategies...
  18. pmc Mismatch induced speciation in Salmonella: model and data
    Daniel Falush
    Peter Medawar Building for Pathogen Research, Oxford University, Oxford OX1 3SY, UK
    Philos Trans R Soc Lond B Biol Sci 361:2045-53. 2006
    ..enterica subspecies enterica and do not provide the resolution to establish whether new species are presently being formed...