Research Topics
| Daniel FalushSummaryAffiliation: Max-Planck-Institute for Infection Biology Country: Germany Publications
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Detail Information
Publications
Inference of population structure using multilocus genotype data: linked loci and correlated allele frequenciesDaniel Falush
Department of Molecular Biology, Max Planck Institut für Infektionsbiologie, Schumann Strasse 21 22, 10117 Berlin, Germany
Genetics 164:1567-87. 2003..The methods are implemented in a program, structure, version 2.0, which is available at http://pritch.bsd.uchicago.edu...- An African origin for the intimate association between humans and Helicobacter pyloriBodo Linz
Department of Molecular Biology, Max Planck Institut für Infektionsbiologie, D 10117 Berlin, Germany
Nature 445:915-8. 2007..pylori before their migrations from Africa and demonstrate that H. pylori has remained intimately associated with their human host populations ever since... - Microevolution of Helicobacter pylori during prolonged infection of single hosts and within familiesGiovanna Morelli
Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany
PLoS Genet 6:e1001036. 2010..Comparisons with the recent literature show that short-term mutation rates vary dramatically in different bacterial species and can span a range of several orders of magnitude... 
Traces of human migrations in Helicobacter pylori populationsDaniel Falush
Department of Molecular Biology, , 10117 Berlin, Germany
Science 299:1582-5. 2003..Subsequent spread can be attributed to human migratory fluxes such as the prehistoric colonization of Polynesia and the Americas, the neolithic introduction of farming to Europe, the Bantu expansion within Africa, and the slave trade...- Sex and virulence in Escherichia coli: an evolutionary perspectiveThierry Wirth
Department of Molecular Biology, Schumannstrasse 21 22, Max Planck Institut für Infektionsbiologie, 10117 Berlin, Germany
Mol Microbiol 60:1136-51. 2006..This long-term pattern of evolution was observed in genes distributed throughout the genome, and thereby is the likely result of episodic selection for strains that can escape the host immune response... - Distinguishing human ethnic groups by means of sequences from Helicobacter pylori: lessons from LadakhThierry Wirth
Department of Molecular Biology, Max Planck Institut für Infektionsbiologie, Schumannstrasse 21 22, 10117 Berlin, Germany
Proc Natl Acad Sci U S A 101:4746-51. 2004..H. pylori sequence analysis has the potential to become an important tool for unraveling short-term genetic changes in human populations... - Hybrid Vibrio vulnificusNaiel Bisharat
University of Oxford, Oxford, United Kingdom
Emerg Infect Dis 11:30-5. 2005..This novel observation shows yet another way in which epidemic organisms arise... - Inferring human colonization history using a copying modelGarrett Hellenthal
Department of Statistics, University of Oxford, Oxford, United Kingdom
PLoS Genet 4:e1000078. 2008..A detailed depiction of the peopling of the world is available in animated form... - Origin of extant domesticated sunflowers in eastern North AmericaAbigail V Harter
Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
Nature 430:201-5. 2004..We show that extant domesticates arose in eastern North America, with a substantial genetic bottleneck occurring during domestication... - A bimodal pattern of relatedness between the Salmonella Paratyphi A and Typhi genomes: convergence or divergence by homologous recombination?Xavier Didelot
Department of Statistics, University of Oxford, Oxford OX1 3SY, United Kingdom
Genome Res 17:61-8. 2007..We propose that recombination between Typhi and Paratyphi A has allowed the exchange of gene variants that are important for their adaptation to their common ecological niche, the human host... 
Convergence of Campylobacter species: implications for bacterial evolutionSamuel K Sheppard
Departments of Zoology and Statistics, University of Oxford, Peter Medawar Building, South Parks Road, Oxford OX1 3SY, UK
Science 320:237-9. 2008..Bacterial speciation can therefore occur by mechanisms analogous to those seen in metazoans, where genetic diversification and incipient speciation caused by ecological factors have been reported in several genera...- Plastic cells and populations: DNA substrate characteristics in Helicobacter pylori transformation define a flexible but conservative system for genomic variationSteven M Levine
Dept of Medicine, New York University School of Medicine, New York, NY 10016, USA
FASEB J 21:3458-67. 2007..pylori population biology... - Host-associated genetic import in Campylobacter jejuniNoel D McCarthy
Department of Zoology, University of Oxford, Oxford, United Kingdom
Emerg Infect Dis 13:267-72. 2007..Assignment using this signature enables improved prediction of source for pathogens that undergo frequent genetic recombination... - Inference of bacterial microevolution using multilocus sequence dataXavier Didelot
Department of Statistics, University of Oxford, Oxford OX1 3SY, United Kingdom
Genetics 175:1251-66. 2007..The software used in this article, ClonalFrame, is available from http://bacteria.stats.ox.ac.uk/... - Genome-wide association mapping in bacteria?Daniel Falush
Peter Medawar Building for Pathogen Research, South Parks Road, Oxford OX1 3SY, UK
Trends Microbiol 14:353-5. 2006..Here, we describe how association mapping could be successfully applied to bacteria and outline the necessary sampling and genotyping strategies... - Sequence typing and comparison of population biology of Campylobacter coli and Campylobacter jejuniKate E Dingle
Nuffield Department of Clinical Sciences, Oxford University, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
J Clin Microbiol 43:340-7. 2005..The use of a common MLST scheme allows direct comparisons of the population biology and molecular epidemiology of these two closely related human pathogens... - Genomic changes during chronic Helicobacter pylori infectionChristian Kraft
, Medizinische Hochschule Hannover, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany
J Bacteriol 188:249-54. 2006..These results suggest that adaptation of H. pylori to the host individual may principally occur through sequence changes rather than loss or gain of genes... - Mismatch induced speciation in Salmonella: model and dataDaniel Falush
Peter Medawar Building for Pathogen Research, Oxford University, Oxford OX1 3SY, UK
Philos Trans R Soc Lond B Biol Sci 361:2045-53. 2006..enterica subspecies enterica and do not provide the resolution to establish whether new species are presently being formed...